Patents
Patents for C07D 451 - Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.02,4] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof (5,273)
05/1989
05/02/1989US4826838 Analgesic carbocyclic and heterocyclic carbonylmethylene-and carbonylmethypipidines and-pyrrolidines
04/1989
04/26/1989EP0313393A2 Benzoxazine compounds and pharmaceutical use thereof
04/05/1989EP0310073A2 Non-peptidyl beta-aminoacyl aminodiol carbamates as anti-hypertensive agents
04/05/1989EP0310072A2 Non-peptidyl beta-succinamidoacyl aminodiols as anti-hypertensive agents
04/05/1989EP0310071A2 Non-peptidyl alpha-aminoacyl aminodiol carbamates as anti-hypertensive agents
04/05/1989EP0310070A2 Alpha-aminoacyl beta-aminoacyl aminodiols as anti-hypertensive agents
03/1989
03/29/1989EP0309424A2 New amidino derivatives
03/29/1989EP0309423A2 New benzimidazoline-2-oxo-1-carboxylic acid derivatives useful as 5-ht receptor antagonists
03/29/1989EP0309422A2 New amidino tricycle derivatives
03/22/1989CN1031841A Improvements in or relating to specific 5-ht3 antagonists
03/15/1989EP0307172A2 Improvements in or relating to specific 5-HT3 antagonists
03/15/1989CN1031701A Improvement relating to n-substituted benzamides
03/08/1989EP0306148A2 Azabicyclic ethers
03/08/1989EP0305744A2 Quinoline, naphthyridine and benzoxazine-carboxylic acid derivatives and their use as antibacterial agents
03/02/1989DE3827253A1 Esters and amides of cyclic carboxylic acids and cyclic alcohols and amines, processes for their preparation and therapeutic compositions containing them
02/1989
02/28/1989US4808588 Headaches, central nervous system disorders, antiarrhythmia antiemetic agents
02/28/1989US4808582 Learning enhancement
02/15/1989EP0303512A1 Substituted dibenzocycloheptenimines
02/15/1989EP0303421A1 Polyhydro derivatives of dibenzocyclohexen-, dibenzocyclohepten-, and dibenzocyclooctenimines
02/08/1989EP0302699A2 Improvements relating to n-substituted benzamides
02/07/1989US4803199 Pharmaceutically useful heterocyclic and carbocyclic acid esters and amides of alkylene bridged piperidines
01/1989
01/17/1989CA1248956A1 Endo-8,8-dialkyl-8-azoniabicyclo ¬3.2.1| octane-6, 7-exo-epoxy-3-alkyl-carboxylate salts, a process for their preparation, and therapeutic compositions which contain them as active principle
01/10/1989US4797406 Amides and esters containing bridged piperidines and use as serotonin M antagonists
01/10/1989US4797387 Certain pharmaceutically useful ureas
12/1988
12/07/1988EP0294292A2 Derivative of benzo[b]thiophene-7-carboxylic acid, process for its preparation and pharmaceutical compositions containing it
12/06/1988US4789673 Antiserotonine agents
11/1988
11/22/1988US4786643 Treatment of migraine, cluster headaches and trigeminal neuralgia
11/08/1988US4783534 N-alkylnorscopines and acid addition salts thereof
11/08/1988US4783478 Treatment of emesis, nausea and vomiting
11/02/1988EP0289170A2 Azabicyclic compounds, process for their preparation and pharmaceutical compositions containing them
11/01/1988CA1244028A1 Pyrimidine derivatives
10/1988
10/25/1988US4780467 Esters of N-alkyl-nortropines and their quaternary derivatives having anti-bronchospastic activity, and pharmaceutical compositions containing them
10/19/1988EP0287196A1 Indole derivatives, process for their preparation and pharmaceutical compositions containing them
09/1988
09/27/1988US4774249 Bactericides
09/20/1988US4772706 Process for quinoline-3-carboxylic acid antibacterial agents
09/20/1988US4772695 Process for the preparation of vinyl carbamates
08/1988
08/31/1988EP0279990A2 Use of heterocyclic derivatives in the treatment of cognitive disorders
08/24/1988EP0279512A2 Use of certain 5-HT3 receptor antagonists in the treatment of visceral pain
08/24/1988EP0279114A1 Medicaments for the treatment or prevention of the withdrawal syndrome
08/17/1988EP0278173A2 Use of heterocyclic derivatives in the treatment of depressions
08/09/1988US4762832 Treating cerebral insufficiency
07/1988
07/05/1988US4755603 Process for the preparation of norscopine
06/1988
06/16/1988WO1988004172A1 Pharmaceutical compositions for treatment of hyperproliferate skin disease
06/02/1988WO1988003801A1 Medicaments for treatment or prevention of withdrawal syndrome
04/1988
04/20/1988EP0264183A1 Derivatives of 5-methyl-10,11-dihydro-5H-dibenzo-(a,d) cyclohepten-5,10-imine
04/12/1988CA1235121A1 Process for the preparation of vinyl carbamates and novel vinyl carbamates
03/1988
03/30/1988EP0261964A2 Azabicyclic compounds and their use as 5-ht3 receptor antagonists
03/30/1988EP0261763A1 Novel bridged bicyclic N-heterocycles
03/09/1988EP0258800A2 3-Bromo-2,6-dimethoxybenzamides, their preparation and use
02/1988
02/23/1988US4727160 Hypotensive intermediates
02/18/1988DE3724059A1 Verwendung von mono- und bicyclischen carbocyclischen und heterocyclischen carbonsaeureestern und -amiden von stickstoffhaltigen alkoholen und aminen sowie deren saeureadditionssalzen und quaternaeren ammoniumsalzen sowie von imidazolyl-carbazolen zur behandlung von psychiatrischen stoerungen wie sozialen entzugserscheinungen, manisch-depressiven psychosen, psychosen und anderen in verbindung mit stress stehende krankheiten, stoerungen des wachheitszustandes wie geriatrischen krankheitsbildern, ferner zur behandlung der rhinitis, der lungenembolie und zur verbesserung der nasalen resorption anderer wirkstoffe .......... Use of mono- and bicyclic carbocyclic and heterocyclic carbonsaeureestern and amides of nitrogen-containing alcohols and amines and ammonium salts saeureadditionssalzen thereof and quaternary, as well as imidazolyl -carbazoles for the treatment of psychiatric disorders such as social withdrawal symptoms, manic-depressive psychosis, psychosis and others in connection with stress related diseases, disorders of the alertness state as geriatric disease images, and also for the treatment of rhinitis, pulmonary embolism and for the improvement of nasal resorption other ingredients ..........
02/16/1988US4725603 Antiemetics; nervous system disorders; headaches; antiarrhythmia agents
02/03/1988EP0255297A2 Azabicyclic compounds, process for their preparation, and their pharmaceutical use
01/1988
01/26/1988US4721783 Anti-spasmodic agents having a heterocyclic ring
01/26/1988US4721720 Irritable bowel syndrome
12/1987
12/02/1987EP0247266A1 Indole derivatives having an azabicyclic side chain, process for their preparation, intermediates, and pharmaceutical compositions
11/1987
11/18/1987CN87102972A Oxadiazoles useful in the treatment of senile dementia
11/10/1987US4705858 Azabicyclo[3.3.1]nonanes
10/1987
10/22/1987DE3706978A1 Process for obtaining alkaloids
09/1987
09/30/1987EP0239309A2 Oxadiazoles useful in the treatment of senile dementia
09/30/1987EP0238982A1 Anticholinergic compounds, pharmaceutical compositions and method of treatment
09/24/1987WO1987005603A1 Anticholinergic compounds, pharmaceutical compositions and method of treatment
09/22/1987CA1227195A1 Cinnamoic compounds, the process for preparing same and the use thereof in therapeutics
09/16/1987EP0236673A2 Process for quinoline-3-carboxylic acid antibacterial agents
09/09/1987EP0235878A2 Novel compounds
09/02/1987EP0234872A1 Carboxamides useful as antiemetic or antipsychotic agents
09/02/1987EP0234400A1 Esters of N-alkyl-nortropines and their quaternary derivatives having anti-bronchospastic activity, process for their preparation and pharmaceutical compositions containing them
08/1987
08/19/1987CN87100298A Improved process for quinoline-3-carboxylic acid antibacterial agents
08/13/1987WO1987004710A1 Process for obtaining a tropa-alcaloid raw extract from undried plant elements
08/13/1987DE3603678A1 Verfahren zur gewinnung eines tropa-alkaloids-rohextraktes aus ungetrockneten pflanzenteilen Process for the recovery of a tropa-alkaloid crude extract from undried parts of plants
08/05/1987EP0230718A1 Substituted benzamides and benzoates
07/1987
07/22/1987EP0229444A2 Medicaments for the treatment of anxiety
07/15/1987CN86107627A Process for preparation of 4-benzyl-1-(2h)-phthalazinonr derivates
06/1987
06/02/1987US4670456 4-Aminocarbonylaminomethyl-1-benzylpyrrolidin-2-ones as nootropic agents and as agents for treating cerebral insufficiency
05/1987
05/27/1987EP0223385A2 8-Azabicyclo[3,2,1]octane and 9-azabicyclo[3,3,1]nonane derivatives
05/20/1987EP0222191A1 4-Benzyl-1-2(H)-phthalazinone derivatives
05/19/1987US4666993 Alkenoyl isocyanate addition polymers
05/19/1987CA1221969A1 3-methylflavone-8-carboxylic acid esters
05/14/1987DE3634942A1 Novel 4-benzyl-1-(2H)-phthalazinone derivatives
05/06/1987EP0220339A1 Azabicycloalkyl derivatives
04/1987
04/14/1987CA1220473A2 Nortropyl (alkyl) benzamides
04/07/1987CA1220141A1 Treatment of migraine with tropyl benzoate derivatives
03/1987
03/25/1987EP0215545A2 Use of benzamido-azabicyclo compounds in the treatment of migraine, nausea, vomiting and cardiac arrhythmia
03/18/1987EP0214600A2 Cephalosporin derivatives
03/17/1987CA1219266A1 Pseudotropyl halogenobenzoates and their use in migraine treatment
03/12/1987DE3531282A1 Therapeutic use of mono- or dicarbocyclic or heterocyclic carboxylic acid or sulphonic acid esters or amides
03/12/1987DE3531281A1 Therapeutic use of mono- or dicarbocyclic or heterocyclic carboxylic acid or sulphonic acid esters or amides
02/1987
02/17/1987US4643995 Analgesic pyridine-2-ethers or pyridine-2-thioethers having a nitrogen-containing cycloaliphatic ring
02/17/1987CA1218062A1 Nortropyl (alkyl) benzamides
01/1987
01/07/1987EP0207621A2 Functional polymers and their production
12/1986
12/23/1986CA1215714A1 Tropyl and pseudotropyl alkyl-benzoates and their use in migraine treatment
11/1986
11/12/1986EP0201165A2 Medicaments for the treatment of emesis
11/05/1986EP0200444A2 Azabicyclononyl-indazole-carboxamide having 5-HT antagonist activity
11/05/1986EP0200307A1 Improved process for production of quinoline-3-carboxylic acid antibacterial agents
10/1986
10/15/1986CN85101353A Process for the preparation of new pyridine-2-ethers or pyridine-2-thioethers having a nitrogen-containing cycloalkyl ring
09/1986
09/24/1986EP0195498A2 Tropane derivatives, their synthesis and their use
09/24/1986CN86101806A Improved process for quinoline-3-cabroxylic acid antibacterial agents
08/1986
08/26/1986US4608377 Quaternary 6,11-dihydro-dibenzo-[b,e]-thiepine-11-N-alkylnorscopine ethers having spasmolytic activity
08/12/1986CA1209574A1 Nor-tropane and granatane derivatives, the process for preparing the same and their application in therapeutics
07/1986
07/30/1986EP0189002A2 Treatment of gastrointestinal disorders using 5-HT3 antagonists
1 ... 41 42 43 44 45 46 47 48 49 50 51 52 53