| Patents for C07D 451 - Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.02,4] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof (5,273) |
|---|
| 07/15/2014 | US8779143 Crystalline forms of maraviroc phosphate and process for maraviroc amorphous form |
| 07/10/2014 | US20140194349 HIV Protease Inhibiting Compounds |
| 07/08/2014 | US8772492 Substituted isoquinoline and isoquinolinone derivatives |
| 07/08/2014 | CA2650009C Il-8 receptor antagonists |
| 07/08/2014 | CA2635850C Heterocyclic janus kinase 3 inhibitors |
| 07/03/2014 | WO2014102829A1 Crystalline atropine sulfate |
| 07/03/2014 | WO2014102589A1 Quinazolin-4(3h)-one-type piperidine compounds and uses thereof |
| 07/03/2014 | US20140187544 Oxime-substituted-quinoxaline-type piperidine compounds and uses thereof |
| 07/03/2014 | US20140187531 Apoptosis promoters |
| 07/02/2014 | CN102718760B 一种曲司氯铵合成工艺 One kind of trospium chloride synthesis process |
| 06/25/2014 | CN103889951A 唑类衍生物 Azole derivative |
| 06/25/2014 | CN103880837A 一种西托溴铵的合成方法 Synthesis method Esposito bromide |
| 06/19/2014 | WO2014092100A1 Heterocyclic compound |
| 06/19/2014 | US20140171404 Autotaxin inhibitors |
| 06/18/2014 | CN103864777A Simple synthesis method of scopolamine butylbromide |
| 06/18/2014 | CN102007124B Pyrimidine-2-amine compounds and their use as inhibitors of jak kinases |
| 06/18/2014 | CN101506140B Cyclic 11-beta hydroxysteroid dehydrogenase type I inhibitors |
| 06/12/2014 | US20140163063 Quinolinone-carboxamide compounds as 5-ht4 receptor agonists |
| 06/12/2014 | US20140163062 Remedy for psychoneurotic diseases |
| 06/12/2014 | US20140162999 Pim kinase inhibitors and preparation methods and use in medicinal manufacture thereof |
| 06/12/2014 | US20140162983 Compositions and Methods for the Production of Pyrimidine and Pyridine Compounds with BTK Inhibitory Activity |
| 06/11/2014 | EP2739622A1 Precursor compounds for the radiosynthesis of [18f]norchloro-fluorohomoepibatidine |
| 06/11/2014 | CN101595100B Heterocyclic-substituted piperidine as orl-1 ligands |
| 06/10/2014 | US8748457 2-amino-2- [8-(dimethyl carbamoyl)- 8-aza- bicyclo [3.2.1] oct-3-yl]-exo- ethanoyl derivatives as potent DPP-IV inhibitors |
| 06/05/2014 | US20140155418 Receptor-Type Kinase Modulators and Methods of Use |
| 06/05/2014 | US20140155408 Pyruvate kinase activators for use in therapy |
| 06/04/2014 | CN1585772B Chemokine receptor antagonists and methods of use thereof |
| 06/03/2014 | CA2568804C Pyrrolopyrimidine and pyrrolopyridine derivatives substituted with a cyclic amino group as crf antagonists |
| 05/27/2014 | CA2789645C Cyclic amine compound and acaricide |
| 05/27/2014 | CA2631949C Micronization method for preparing virtually anhydrous tiotropium bromide monohydrate |
| 05/27/2014 | CA2603654C Crystalline hydrochloride salt of a quinolinone-carboxamide compound or a solvate thereof |
| 05/22/2014 | WO2014078611A1 Dihydropyrazole gpr40 modulators |
| 05/14/2014 | CN103787954A 一类氟取代的环状胺类化合物及其制备方法、药物组合物和用途 A class of fluorine-substituted cyclic amine compounds and their preparation, pharmaceutical compositions and uses |
| 05/14/2014 | CN101484424B 治疗化合物 Therapeutic compounds |
| 05/08/2014 | WO2014067499A1 Stabilization of tiotropium solvates |
| 05/07/2014 | CN103781784A 用于辐射合成[<sup>18</sup>F]去氯-氟占据最高分子轨道地棘蛙素的前驱体化合物 Fluorine precursor compounds occupy the highest molecular orbital epibatidine of - for radiation synthesis [<sup> 18 </ sup> F] to chlorine |
| 05/07/2014 | CN103772379A 一种曲司氯铵关键中间体的制备方法 Preparation method of trospium chloride key intermediates |
| 05/07/2014 | CN101648950B 噻托铵盐、其医药制剂及其用途 Tiotropium salts, their pharmaceutical formulations and their use |
| 05/06/2014 | CA2573373C Method for producing tiotropium salts and silicon derivatives as intermediates |
| 05/01/2014 | WO2014063587A1 Fluorine substituted cyclic amine compounds and preparation methods, pharmaceutical compositions, and uses thereof |
| 04/29/2014 | CA2661741C N-pyridylpiperidine compound, method for producing the same, and pest control agent |
| 04/23/2014 | EP2721008A1 Hydroxy substituted isoquinolinone derivatives |
| 04/22/2014 | US8703165 Spiro fused 1-amino-piperdine pyrrolidine dione derivatives with pesticidal activity |
| 04/22/2014 | CA2637214C Process for preparing 8-azabicylo[3.2.1]octan-3-one intermediates to 5-ht4 receptor agonist compounds |
| 04/22/2014 | CA2620418C Benztropine compounds and uses thereof |
| 04/17/2014 | WO2014056083A1 Kinase inhibitors and method of treating cancer with same |
| 04/16/2014 | EP2718280A1 Compounds having muscarinic receptor antagonist and beta2 adrenergic receptor agonist activity |
| 04/10/2014 | WO2014054053A1 Spirocyclic compounds, compositions and medicinal applications thereof |
| 04/03/2014 | US20140094450 Benzoimidazole-carboxylic acid amide derivatives as apj receptor modulators |
| 04/03/2014 | US20140093518 Chemically Programmed Vaccination |
| 04/01/2014 | US8686148 Process for preparing new tiotropium salts, new tiotropium salts as such and pharmaceutical compositions thereof |
| 03/27/2014 | WO2014045031A1 Bicyclic aza compounds as muscarinic m1 receptor agonists |
| 03/27/2014 | WO2014044738A1 Benzoimidazole-carboxylic acid amide derivatives as apj receptor modulators |
| 03/27/2014 | US20140088086 Compounds and methods for treatment of hypertension |
| 03/25/2014 | US8680115 Tetrahydroquinoline analogues as muscarinic agonists |
| 03/20/2014 | WO2014042605A1 New tiotropium bromide crystalline form |
| 03/20/2014 | US20140080856 Crystalline forms of an 8-azabicyclo[3.2.1]octane compound |
| 03/20/2014 | US20140080855 8-azabicyclo[3.2.1]octyl-2-hydroxybenzamide compounds as mu opioid receptor antagonists |
| 03/20/2014 | US20140079634 Labeled pe2i formulation and method |
| 03/19/2014 | CN103649084A 1,4-disubstituted 1,2,3-triazoles, methods for preparing same, and diagnostic and therapeutic uses thereof |
| 03/19/2014 | CN103641816A Compounds and compositions as protein kinase inhibitors |
| 03/13/2014 | US20140073635 Substituted Imidazopyridinyl-Aminopyridine Compounds |
| 03/12/2014 | EP2705838A1 Tiotropium preparations |
| 03/12/2014 | CN203469997U Device for preparing key intermediate of trospium chloride |
| 03/11/2014 | US8669367 Method for producing 2-azaadamantane |
| 03/05/2014 | EP2702053A2 Novel rock inhibitors |
| 03/04/2014 | US8664242 8-azabicyclo[3.2.1]octane compounds as mu opioid receptor antagonists |
| 02/27/2014 | US20140057935 Novel forms of tiotropium bromide and processes for preparation thereof |
| 02/26/2014 | EP2699570A1 1,4-disubstituted 1,2,3-triazoles, methods for preparing same, and diagnostic and therapeutic uses thereof |
| 02/25/2014 | US8658796 Complexes of ruthenium, method of production thereof and use thereof as (pre)catalysts of the metathesis reaction |
| 02/25/2014 | US8658671 Crystalline form of a quinolinone-carboxamide compound |
| 02/25/2014 | US8658654 Receptor-type kinase modulators and methods of use |
| 02/20/2014 | WO2014026330A1 3-AMINOCYCLOALKYL COMPOUNDS AS RORgammaT INHIBITORS AND USES THEREOF |
| 02/20/2014 | US20140051687 Substituted indole compounds having nos inhibitory activity |
| 02/20/2014 | US20140051679 Kinase inhibitors and method of treating cancer with same |
| 02/20/2014 | US20140051676 Triazine-oxadiazoles |
| 02/18/2014 | US8653145 Method for alleviating climacteric symptoms |
| 02/13/2014 | US20140045817 Triazolopyridine compounds as pim kinase inhibitors |
| 02/12/2014 | CN101573354B Substituted isoquinolines and their use as Rho-kinase inhibitors |
| 02/06/2014 | US20140038980 Compounds, compositions and methods for the treatment of amyloid diseases and synucleinopathies such as alzheimer's disease, type 2 diabetes, and parkinson's disease |
| 02/05/2014 | CN103562198A Compounds having muscarinic receptor antagonist and beta2 adrenergic receptor agonist activity |
| 02/04/2014 | US8642764 Julolidine conjugates and methods for their preparation and use |
| 02/04/2014 | CA2491191C Receptor-type kinase modulators and methods of use |
| 01/30/2014 | US20140031349 Inhibitors of the renal outer medullary potassium channel |
| 01/30/2014 | US20140030191 1,4-disubstituted 1,2,3-triazoles, methods for preparing same, and diagnostic and therapeutic uses thereof |
| 01/29/2014 | EP2078010B1 Polycyclic heteroaryl substituted triazoles useful as axl inhibitors |
| 01/29/2014 | CN102267993B Polyhydroxy desmethyl tropane compounds and preparation method and use thereof |
| 01/23/2014 | WO2014014962A1 5ht3 receptor antagonists |
| 01/23/2014 | WO2014014951A1 5-ht3 receptor antagonists |
| 01/23/2014 | US20140024643 Bridged heterocyclic compounds and methods of use |
| 01/22/2014 | CN103534249A Novel rock inhibitors |
| 01/21/2014 | US8633218 8-azabicyclo[3.2.1]oct-2-ene derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
| 01/16/2014 | WO2014009447A1 ARYL SULTAM DERIVATIVES AS RORc MODULATORS |
| 01/16/2014 | US20140018317 Targeted nitroxide agents |
| 01/16/2014 | CA2876449A1 Aryl sultam derivatives as rorc modulators |
| 01/15/2014 | EP2684871A1 Heteroaryl pyrrolidinyl and piperidinyl ketone derivatives |
| 01/14/2014 | US8628759 Soft anticholinergic esters |
| 01/09/2014 | WO2014007144A1 Method for producing alicyclic n-oxyl compound |
| 01/09/2014 | WO2014005274A1 Multi-substituted 8-nitrogen heterocyclic ring [3.2.1] octane compound |
| 01/08/2014 | EP2681213A1 Anhydrous crystalline form of tiotropium bromide |