Patents
Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892)
08/1986
08/06/1986EP0189784A1 Human natural inhibitor of collagenases
08/06/1986EP0189707A2 Recombinant DNA which can be introduced into plant cells
08/06/1986EP0189481A1 Insulin-like Growth factor II.
08/05/1986US4604359 Microbial expression of a gene for human growth hormone
07/1986
07/31/1986WO1986004244A1 Chemical probes for left-handed dna and chiral metal complexes as z-specific antitumor agents
07/31/1986WO1986004239A1 Brain derivable polypeptide factors and antibodies
07/30/1986EP0188677A2 Genes from pichia histidine pathway and uses thereof
07/29/1986US4603112 Modified vaccinia virus
07/22/1986US4601980 Microbial expression of a gene for human growth hormone
07/22/1986CA1208147A1 Oligonucleotide therapeutic agent and methods of making same
07/17/1986WO1986004064A1 A compound and a composition for therapeutic or diagnostic use and the use of such compound and composition for therapeutic treatment and isolation of shigatoxine
07/16/1986EP0187391A2 Graft polymers from cross-linked polymers and polyoxyethylene, their preparation and use
07/15/1986CA1207686A1 High efficiency eukaryotic metallothionein promoter system
07/15/1986CA1207685A1 Chimeric cloning vectors for use in streptomyces and e. coli
07/15/1986CA1207684A1 Cloning vehicles for polypeptide expression in microbial hosts
07/15/1986CA1207683A1 Nonionic nucleic acid alkyl and aryl methylphosphonates and processes for manufacture and use thereof
07/08/1986US4599303 Nucleic acid hybridization assay employing probes crosslinkable to target sequences
07/08/1986CA1207251A1 Vectors and methods for making such vectors and for expressing cloned genes
07/03/1986WO1986003775A1 Dog and horse interferons
07/03/1986WO1986003774A1 A method of transforming fungi with a vector
07/03/1986WO1986003751A2 Purification, production and use of tumor necrosis factors
07/02/1986EP0186482A2 Hypocholesterolemically active RNA fractions
07/02/1986EP0186098A1 Equine interferons
07/01/1986US4598049 General purpose gene synthesizer
06/1986
06/25/1986EP0185573A1 Expression and excretion of polypeptides in eucaryotes under the control of an adenovirus promoter
06/25/1986EP0185547A2 Polynucleotide hybridization assays employing catalyzed luminescence
06/25/1986EP0185512A1 Method for stabilizing extra-chromosomal elements in bacteria during cultivation, extra-chromosomal elements, transformed bacteria and a method of producing a desired product in transformed bacteria
06/25/1986EP0185494A2 Detection of specific sequences in nucleic acids
06/24/1986CA1206457A1 Synthesis of compounds
06/19/1986WO1986003520A1 Method for the production of erythropoietin
06/19/1986WO1986003410A1 A cloning vehicle for cloning a large fragment of dna and a vaccine comprising 987p fimbrial protein
06/19/1986WO1986003408A1 Recombinant alveolar surfactant protein
06/11/1986EP0184365A2 Improvements in the treatment of tumors in mammals
06/11/1986EP0184187A2 Mouse-human chimaeric immunoglobulin heavy chain, and chimaeric DNA encoding it
06/11/1986EP0184056A2 Large scale production of DNA probes
06/11/1986EP0183800A1 Method of detection nucleic acid sequences
06/10/1986CN85106190A Hepatitis b virus surface antigen and production thereof
06/10/1986CA1205764A1 Cloning vectors for polypeptide expression in microbial hosts
06/05/1986WO1986003225A1 cDNA CLONES CODING FOR POLYPEPTIDES EXHIBITING HUMAN GRANULOCYTE MACROPHAGE AND EOSINOPHIL CELLULAR GROWTH FACTOR ACTIVITY
06/04/1986EP0183071A2 Regulatory region for heterologous gene expression in yeast
06/03/1986US4593089 Determining aminoglycosides
06/03/1986CA1205400A1 Hla typing method and cdna probes used therein
05/1986
05/28/1986EP0182562A2 Process for a thermo-inducible gene expression in Gram positive bacteria, Bacillus subtilis strains containing plasmids which induce such an expression and portable vector systems
05/28/1986EP0182383A1 Process for the preparation of oligo- and polydeoxyribonucleotides
05/27/1986US4591614 Preparation of oligodeoxyribonucleoside alkyl or arylphosphonates
05/27/1986CA1205026A1 Expression of polypeptides in yeast
05/22/1986WO1986002929A1 Nucleotide analogs for nucleic acid labeling and detection
05/21/1986EP0181491A1 Device for simultaneously carrying out a plurality of chemical reaction steps
05/20/1986US4590162 Inserting foreign dna into chromosome of gramnegative bacterium
05/20/1986CA1204682A1 Adaptors, and synthesis and cloning of proinsulin genes
05/20/1986CA1204681A1 Method and vector organism for controlled accumulation of cloned heterologous gene products in bacillus subtilis ii
05/20/1986CA1204680A1 Multiple reactor system and method for polynucleotide synthesis
05/16/1986EP0165313A4 Nucleic acid hybridization assay.
05/14/1986EP0181150A1 Recombinant proteins of viruses associated with lymphadenopathy syndrome and/or acquired immune deficiency syndrome
05/14/1986EP0180964A1 Recombinant DNA, microorganism transformed therewith, and process for producing human Cu-Zn superoxide dismutase using the transformed microorganism
05/14/1986EP0180945A2 Nucleotide derivative
05/13/1986US4588684 a-Factor and its processing signals
05/13/1986US4588682 Denaturing, immobilization, solvents
05/13/1986CA1204398A1 Microbial degradation of obnoxious organic wastes into innocuous materials
05/09/1986WO1986002666A1 Methods for protein binding enzyme complementation assays
05/06/1986US4587044 Linkage of proteins to nucleic acids
05/06/1986CA1204108A1 Uracil derivatives, and production and use of same
04/1986
04/24/1986WO1986002383A1 Envelope antigens of lymphadenopathy associated virus and their applications
04/24/1986WO1986002381A1 Human tumor necrosis factor
04/24/1986WO1986002271A1 Promotion of wound healing with human epidermal growth factor prepared from recombinant dna
04/23/1986EP0178978A1 Cloned DNA sequences, hybridizable with genomic RNA of lymphadenopathy-associated virus (LAV)
04/16/1986EP0177957A2 Expression of biologically active platelet derived growth factor analogs in eucaryotic cells
04/16/1986EP0177827A2 Synthetic signal sequence for the transportation of proteins in expression systems
04/16/1986EP0177497A1 Immobilization of nucleic acids
04/15/1986US4582800 Interferon cloned onto bacteria plasmid
04/15/1986US4582789 Containing alkylating intercalation moiety
04/15/1986EP0155950A4 Oligonucleotide polymeric support system.
04/15/1986CA1203237A1 Phosphoramidite compounds and processes
04/15/1986CA1203185A1 Cloned streptomycete gene
04/10/1986WO1986002094A1 A gene for lignin degradation and uses thereof
04/10/1986WO1986002077A1 Production of streptavidin-like polypeptides
04/09/1986EP0177382A1 Mixed probe and its application, its precursor, its preparation and derivatives containing a modified base for this preparation
04/09/1986EP0176916A2 Process for production of gamma-interferon
04/08/1986CA1202918A1 Eukaryotic autonomously replicating segment
04/02/1986EP0176396A1 Probes containing modified adenine groups, their preparation and uses
04/02/1986EP0176321A1 Recombinant dna cosmid shuttle vectors
04/02/1986EP0176170A1 Herpes simplex virus as a vector
04/02/1986EP0175776A1 Hybridization histochemistry.
04/02/1986EP0135587A4 Defined sequence single strand oligonucleotides incorporating reporter groups, process for the chemical synthesis thereof, and nucleosides useful in such synthesis.
04/01/1986US4579941 Thermally-denatured deoxyribonucleic acid MD-011 and antitumor agent
04/01/1986CA1202581A1 Adaptor molecules for dna and their application to synthesis of gene-derived products
03/1986
03/27/1986WO1986001827A1 Cloned dna sequences, hybridizable with genomic rna of lymphadenopathy-associated virus (lav)
03/27/1986WO1986001802A1 Antigens of plasmodium falciparum
03/25/1986CA1202258A1 Expression vector carrying a gene coding for a phosphate-binding protein, a method for preparing the same and a method for producing a polypeptide using the same
03/25/1986CA1202256A2 Microbial expression of quasi-synthetic genes
03/25/1986CA1202255A1 Multifunctional cloning vectors for use in streptomyces, bacillus, and e. coli
03/25/1986CA1202254A1 Oligonucleotide derivatives and production thereof
03/25/1986CA1202253A1 Phosphorylating agent and process for the phosphorylation of organic hydroxyl compounds
03/19/1986EP0174879A1 Polynucleotides covalently bonded to a solid support, and method for their preparation
03/19/1986EP0174525A2 Process for the purification of synthetic oligonucleotides
03/13/1986WO1986001533A1 Production of chimeric antibodies
03/13/1986WO1986001514A1 Solid phase synthesis linkage
03/12/1986EP0174143A1 Novel, distinct family of human leukocyte interferons, compositions containing them, methods for their production, and DNA and transfected hosts therefor
03/12/1986EP0173887A1 Novel interferon alphas
03/11/1986CA1201670A1 Dna fragments taged at least on one end with modified ribonucleotids which can be identified by affine molecules and process for the analyse of such dna fragments