Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892) |
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08/06/1986 | EP0189784A1 Human natural inhibitor of collagenases |
08/06/1986 | EP0189707A2 Recombinant DNA which can be introduced into plant cells |
08/06/1986 | EP0189481A1 Insulin-like Growth factor II. |
08/05/1986 | US4604359 Microbial expression of a gene for human growth hormone |
07/31/1986 | WO1986004244A1 Chemical probes for left-handed dna and chiral metal complexes as z-specific antitumor agents |
07/31/1986 | WO1986004239A1 Brain derivable polypeptide factors and antibodies |
07/30/1986 | EP0188677A2 Genes from pichia histidine pathway and uses thereof |
07/29/1986 | US4603112 Modified vaccinia virus |
07/22/1986 | US4601980 Microbial expression of a gene for human growth hormone |
07/22/1986 | CA1208147A1 Oligonucleotide therapeutic agent and methods of making same |
07/17/1986 | WO1986004064A1 A compound and a composition for therapeutic or diagnostic use and the use of such compound and composition for therapeutic treatment and isolation of shigatoxine |
07/16/1986 | EP0187391A2 Graft polymers from cross-linked polymers and polyoxyethylene, their preparation and use |
07/15/1986 | CA1207686A1 High efficiency eukaryotic metallothionein promoter system |
07/15/1986 | CA1207685A1 Chimeric cloning vectors for use in streptomyces and e. coli |
07/15/1986 | CA1207684A1 Cloning vehicles for polypeptide expression in microbial hosts |
07/15/1986 | CA1207683A1 Nonionic nucleic acid alkyl and aryl methylphosphonates and processes for manufacture and use thereof |
07/08/1986 | US4599303 Nucleic acid hybridization assay employing probes crosslinkable to target sequences |
07/08/1986 | CA1207251A1 Vectors and methods for making such vectors and for expressing cloned genes |
07/03/1986 | WO1986003775A1 Dog and horse interferons |
07/03/1986 | WO1986003774A1 A method of transforming fungi with a vector |
07/03/1986 | WO1986003751A2 Purification, production and use of tumor necrosis factors |
07/02/1986 | EP0186482A2 Hypocholesterolemically active RNA fractions |
07/02/1986 | EP0186098A1 Equine interferons |
07/01/1986 | US4598049 General purpose gene synthesizer |
06/25/1986 | EP0185573A1 Expression and excretion of polypeptides in eucaryotes under the control of an adenovirus promoter |
06/25/1986 | EP0185547A2 Polynucleotide hybridization assays employing catalyzed luminescence |
06/25/1986 | EP0185512A1 Method for stabilizing extra-chromosomal elements in bacteria during cultivation, extra-chromosomal elements, transformed bacteria and a method of producing a desired product in transformed bacteria |
06/25/1986 | EP0185494A2 Detection of specific sequences in nucleic acids |
06/24/1986 | CA1206457A1 Synthesis of compounds |
06/19/1986 | WO1986003520A1 Method for the production of erythropoietin |
06/19/1986 | WO1986003410A1 A cloning vehicle for cloning a large fragment of dna and a vaccine comprising 987p fimbrial protein |
06/19/1986 | WO1986003408A1 Recombinant alveolar surfactant protein |
06/11/1986 | EP0184365A2 Improvements in the treatment of tumors in mammals |
06/11/1986 | EP0184187A2 Mouse-human chimaeric immunoglobulin heavy chain, and chimaeric DNA encoding it |
06/11/1986 | EP0184056A2 Large scale production of DNA probes |
06/11/1986 | EP0183800A1 Method of detection nucleic acid sequences |
06/10/1986 | CN85106190A Hepatitis b virus surface antigen and production thereof |
06/10/1986 | CA1205764A1 Cloning vectors for polypeptide expression in microbial hosts |
06/05/1986 | WO1986003225A1 cDNA CLONES CODING FOR POLYPEPTIDES EXHIBITING HUMAN GRANULOCYTE MACROPHAGE AND EOSINOPHIL CELLULAR GROWTH FACTOR ACTIVITY |
06/04/1986 | EP0183071A2 Regulatory region for heterologous gene expression in yeast |
06/03/1986 | US4593089 Determining aminoglycosides |
06/03/1986 | CA1205400A1 Hla typing method and cdna probes used therein |
05/28/1986 | EP0182562A2 Process for a thermo-inducible gene expression in Gram positive bacteria, Bacillus subtilis strains containing plasmids which induce such an expression and portable vector systems |
05/28/1986 | EP0182383A1 Process for the preparation of oligo- and polydeoxyribonucleotides |
05/27/1986 | US4591614 Preparation of oligodeoxyribonucleoside alkyl or arylphosphonates |
05/27/1986 | CA1205026A1 Expression of polypeptides in yeast |
05/22/1986 | WO1986002929A1 Nucleotide analogs for nucleic acid labeling and detection |
05/21/1986 | EP0181491A1 Device for simultaneously carrying out a plurality of chemical reaction steps |
05/20/1986 | US4590162 Inserting foreign dna into chromosome of gramnegative bacterium |
05/20/1986 | CA1204682A1 Adaptors, and synthesis and cloning of proinsulin genes |
05/20/1986 | CA1204681A1 Method and vector organism for controlled accumulation of cloned heterologous gene products in bacillus subtilis ii |
05/20/1986 | CA1204680A1 Multiple reactor system and method for polynucleotide synthesis |
05/16/1986 | EP0165313A4 Nucleic acid hybridization assay. |
05/14/1986 | EP0181150A1 Recombinant proteins of viruses associated with lymphadenopathy syndrome and/or acquired immune deficiency syndrome |
05/14/1986 | EP0180964A1 Recombinant DNA, microorganism transformed therewith, and process for producing human Cu-Zn superoxide dismutase using the transformed microorganism |
05/14/1986 | EP0180945A2 Nucleotide derivative |
05/13/1986 | US4588684 a-Factor and its processing signals |
05/13/1986 | US4588682 Denaturing, immobilization, solvents |
05/13/1986 | CA1204398A1 Microbial degradation of obnoxious organic wastes into innocuous materials |
05/09/1986 | WO1986002666A1 Methods for protein binding enzyme complementation assays |
05/06/1986 | US4587044 Linkage of proteins to nucleic acids |
05/06/1986 | CA1204108A1 Uracil derivatives, and production and use of same |
04/24/1986 | WO1986002383A1 Envelope antigens of lymphadenopathy associated virus and their applications |
04/24/1986 | WO1986002381A1 Human tumor necrosis factor |
04/24/1986 | WO1986002271A1 Promotion of wound healing with human epidermal growth factor prepared from recombinant dna |
04/23/1986 | EP0178978A1 Cloned DNA sequences, hybridizable with genomic RNA of lymphadenopathy-associated virus (LAV) |
04/16/1986 | EP0177957A2 Expression of biologically active platelet derived growth factor analogs in eucaryotic cells |
04/16/1986 | EP0177827A2 Synthetic signal sequence for the transportation of proteins in expression systems |
04/16/1986 | EP0177497A1 Immobilization of nucleic acids |
04/15/1986 | US4582800 Interferon cloned onto bacteria plasmid |
04/15/1986 | US4582789 Containing alkylating intercalation moiety |
04/15/1986 | EP0155950A4 Oligonucleotide polymeric support system. |
04/15/1986 | CA1203237A1 Phosphoramidite compounds and processes |
04/15/1986 | CA1203185A1 Cloned streptomycete gene |
04/10/1986 | WO1986002094A1 A gene for lignin degradation and uses thereof |
04/10/1986 | WO1986002077A1 Production of streptavidin-like polypeptides |
04/09/1986 | EP0177382A1 Mixed probe and its application, its precursor, its preparation and derivatives containing a modified base for this preparation |
04/09/1986 | EP0176916A2 Process for production of gamma-interferon |
04/08/1986 | CA1202918A1 Eukaryotic autonomously replicating segment |
04/02/1986 | EP0176396A1 Probes containing modified adenine groups, their preparation and uses |
04/02/1986 | EP0176321A1 Recombinant dna cosmid shuttle vectors |
04/02/1986 | EP0176170A1 Herpes simplex virus as a vector |
04/02/1986 | EP0175776A1 Hybridization histochemistry. |
04/02/1986 | EP0135587A4 Defined sequence single strand oligonucleotides incorporating reporter groups, process for the chemical synthesis thereof, and nucleosides useful in such synthesis. |
04/01/1986 | US4579941 Thermally-denatured deoxyribonucleic acid MD-011 and antitumor agent |
04/01/1986 | CA1202581A1 Adaptor molecules for dna and their application to synthesis of gene-derived products |
03/27/1986 | WO1986001827A1 Cloned dna sequences, hybridizable with genomic rna of lymphadenopathy-associated virus (lav) |
03/27/1986 | WO1986001802A1 Antigens of plasmodium falciparum |
03/25/1986 | CA1202258A1 Expression vector carrying a gene coding for a phosphate-binding protein, a method for preparing the same and a method for producing a polypeptide using the same |
03/25/1986 | CA1202256A2 Microbial expression of quasi-synthetic genes |
03/25/1986 | CA1202255A1 Multifunctional cloning vectors for use in streptomyces, bacillus, and e. coli |
03/25/1986 | CA1202254A1 Oligonucleotide derivatives and production thereof |
03/25/1986 | CA1202253A1 Phosphorylating agent and process for the phosphorylation of organic hydroxyl compounds |
03/19/1986 | EP0174879A1 Polynucleotides covalently bonded to a solid support, and method for their preparation |
03/19/1986 | EP0174525A2 Process for the purification of synthetic oligonucleotides |
03/13/1986 | WO1986001533A1 Production of chimeric antibodies |
03/13/1986 | WO1986001514A1 Solid phase synthesis linkage |
03/12/1986 | EP0174143A1 Novel, distinct family of human leukocyte interferons, compositions containing them, methods for their production, and DNA and transfected hosts therefor |
03/12/1986 | EP0173887A1 Novel interferon alphas |
03/11/1986 | CA1201670A1 Dna fragments taged at least on one end with modified ribonucleotids which can be identified by affine molecules and process for the analyse of such dna fragments |