Patents
Patents for C07D 217 - Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems (11,865)
03/1999
03/11/1999WO1998051672A3 A method for the preparation of tertiary amines, a compound useful therefor and alpha-2-receptor active tetrahydroisoquinoline derivatives
03/11/1999CA2294118A1 Oxo-substituted compounds, process of making, and compositions and methods for inhibiting parp activity
03/11/1999CA2294110A1 Alkoxy-substituted compounds, methods, and compositions for inhi biting parp activity
03/11/1999CA2294074A1 Parp inhibitors, pharmaceutical compositions comprising same, and methods of using same
03/10/1999EP0900214A1 Process for preparation of pyrimidine derivatives
03/10/1999CN1210521A Isoquinoline derivatives and drugs
03/09/1999US5880285 Asymmetric hydrogenation of an imine derivative in the presence of an optically active complex containing a diphosphine ligand and iridium
03/04/1999WO1999010313A1 N-aroylphenylalanine derivatives
03/04/1999WO1999009984A1 Pyrrolidine and piperidine modulators of chemokine receptor activity
03/04/1999CA2300121A1 N-alkanoylphenylalanine derivatives
03/04/1999CA2298813A1 Pyrrolidine and piperidine modulators of chemokine receptor activity
03/03/1999EP0898567A1 Novel n-aminoalkyl-1-biphenylenyl-2-carboxamides; new dopamine receptor subtype specific ligands
03/03/1999EP0724570B1 Amidino derivatives useful as nitric oxide synthase inhibitors
03/02/1999US5877278 Solid phase synthesis using two submonomers-an acylating agent, e.g. a haloacetic acid, and a primary amine; cyclization to produce mimetics of drugs; elimination of the necessity of protection groups
03/02/1999US5877185 Therapy for cancer or retrovirus
02/1999
02/24/1999EP0897912A1 Amidino derivatives useful as nitric oxide synthase inhibitors
02/23/1999US5874443 Biosynthesis
02/23/1999US5874023 Electrooptics, displays
02/18/1999WO1999007672A1 Derivatives of 2,5- and 3,5-disubstituted anilines, their preparation and use
02/17/1999EP0896531A1 Il-8 receptor antagonists
02/17/1999CN1208404A Nitrogenous heterocyclic compounds
02/16/1999US5872117 Treating cerebrovascular dementia, senile dementia, alzheimer's dementia, sequelae of ischemic encephalopathy and cerebral apoplexy
02/11/1999WO1999006433A1 Compounds which inhibit leukocyte adhesion mediated by vla-4
02/11/1999CA2290746A1 Compounds which inhibit leukocyte adhesion mediated by vla-4
02/09/1999US5869518 Azacycloalkane derivatives, their preparation and their application in therapy
02/04/1999WO1999005096A2 Urokinase inhibitors
02/04/1999WO1999004775A2 Method of treating dopaminergic and gaba-nergic disorders
02/04/1999CA2297410A1 Method of treating dopaminergic and gaba-nergic disorders
02/04/1999CA2294300A1 Urokinase inhibitors
02/03/1999EP0894085A1 Benzyl(idene)-lactam derivatives, their preparation and their use as selective (ant)agonists of 5-ht1a- and/or 5-ht1d receptors
02/03/1999CN1206589A Process for preparing medicine composition
02/02/1999US5866612 Acetamidine derivatives and their use as inhibitors for the nitric oxide synthase
02/02/1999US5866610 Substituted benzoylguanidines, process for their preparation, their use as a pharmaceutical as inhibitors of the cellular NA+/H+ exchange or as a diagnostic, and pharmaceutical containing them
02/02/1999US5866587 Hydroxamide derivatives of fused piperidine derivatives
02/02/1999US5866583 Substituted 2,4-diaminopyrimidines
01/1999
01/27/1999EP0892787A1 NOVEL $g(a)-HYDROXYLIC ACID DERIVATIVES, THEIR PRODUCTION AND USE
01/27/1999EP0892784A1 Aminoisoquinolines and aminothienopyridine derivatives and their use as anti-inflammatory agents
01/27/1999EP0796243B1 Diaminocyclobutene-3,4-diones
01/26/1999US5863950 Amides or thio amide compounds with hydroxy or ether groups
01/26/1999US5863929 Anticoagulant agents
01/21/1999WO1999002502A2 Sulphonamide derivatives being 5-ht6 receptor antagonists and process for their preparation
01/21/1999WO1999002153A1 Glycol and hydroxyphosphonate peptidomimetics as inhibitors of aspartyl proteases
01/21/1999WO1999002150A1 β-ALKOXYACRYLATES AGAINST MALARIA
01/21/1999WO1999002146A1 Amino acid derivatives
01/21/1999DE19730326A1 New N-substituted sulphonamide or sulphamide compounds
01/21/1999CA2296033A1 Novel compounds
01/21/1999CA2294931A1 .beta.-alkoxyacrylates against malaria
01/19/1999US5861535 Reductive alkylation process to prepare tertiary aminoaryl compounds
01/19/1999US5861412 Dihydro-isoquinoline compounds and their use as pharmaceuticals
01/12/1999US5859248 Process for the production of a β-amino alcohol
01/12/1999US5859051 Antidiabetic agents
01/12/1999US5859027 Antimicrobial agent
01/12/1999US5859002 HIV protease inhibitors
01/07/1999WO1999000371A1 Phenylalkyl derivatives with thrombin-inhibiting effect
01/07/1999EP0889036A1 HIV protease inhibitors
01/07/1999EP0888346A1 Coralyne analogs as topoisomerase inhibitors
01/07/1999EP0888320A1 Novel n-aminoalkyl-2-anthracenecarboxamides; new dopamine receptor subtype specific ligands
01/07/1999EP0888278A1 Antidiabetic agents
01/07/1999DE19727117A1 Phenylalkylderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung Phenylalkylderivate, pharmaceutical compositions containing them and methods for their preparation
01/07/1999CA2288744A1 Phenylalkyl derivatives, pharmaceutical compositions containing these compounds and processes for preparing them
01/05/1999US5856503 Anticholesterol agents
01/05/1999US5856338 Sulfonamide-substituted compounds, processes for their preparation, their use as a medicament or diagnostic, and pharmaceutical preparation comprising them
01/05/1999US5856310 Inhibition of farnesyltransferase
12/1998
12/30/1998WO1998058911A2 Prostaglandin agonists
12/30/1998WO1998058902A1 INHIBITORS OF α4β1MEDIATED CELL ADHESION
12/30/1998EP0887345A1 4'-trifluoromethylbiphenyl-2-carboxylic acid-[2-(2-acetylaminoethyl)-1,2,3,4-tetrahydroisoquinolin-6-yl]amide hydrochloride as apo B-secretion/MTP inhibitors
12/30/1998EP0886637A1 Inhibitors of microsomal triglyceride transfer protein and method
12/30/1998EP0618889B1 Tri-substituted phenyl derivatives and processes for their preparation
12/29/1998US5854234 Amidino dervatives useful as nitric oxide synthase inhibitors
12/29/1998US5853003 Treatment and diagnosis of respiratory disorders using fluorocarbon liquids
12/23/1998EP0885888A1 Isoquinoline derivatives and drugs
12/23/1998EP0729457B1 Diaminocyclobutene-3,4-diones as smooth muscle relaxants
12/23/1998CN1202888A Isoquinoline derivatives and isoquinoline combinatorial libraries
12/23/1998CA2241164A1 Apo b-secretion/mtp inhibitor hydrochloride salt
12/22/1998US5852043 HIV protease inhibitors
12/22/1998US5852007 Cysteine and serine protease inhibitors containing D-amino acid at the P2 position, methods of making same, and methods of using same
12/16/1998CN1202156A Cyclic and heterocyclic n-substituted 'alpha'-iminohydroxamic acid carboxylic acids
12/15/1998US5849923 Heterocyclic-substituted naphthalenyl retinobenzoic acid derivatives
12/15/1998US5849917 Process for the preparation of isoquinoline compounds
12/15/1998US5849775 Substituted benzoylguanidines process for their preparation, their use as a medicament or diagnostic, and pharmaceutical containing them
12/15/1998US5849755 3-amidochromanylsulfonyl(thio)ureas, processes for their preparation, their use, and pharmaceutical preparations comprising them
12/15/1998US5849732 Phenol compound having antioxidative activity and the process for preparing the same
12/10/1998WO1998055449A1 Hydroxamic acid compounds having anticancer and anti-parasitic properties
12/09/1998EP0882717A1 Nitrogenous heterocyclic compounds
12/09/1998EP0882029A1 Heterocyclic derivatives as antidiabetic and antiobesity agents
12/09/1998EP0882020A1 Process for the preparation and isolation of atracurium besylate
12/09/1998CN1201486A Color-safe bleach boosters, compositions and laundry methods employing same
12/09/1998CN1041087C Arylacetamides, preparation method and use thereof
12/08/1998US5847144 Process for manufacturing α,α'-diaminoalcohol
12/08/1998US5847115 Azetidinone compound and process for preparation thereof
12/08/1998US5847008 Method of treating diabetes and related disease states
12/08/1998US5846993 HIV protease inhibitors
12/03/1998WO1998054149A1 Process for obtaining quinapryl hydrochloride and solvates useful for isolating and purifying quinapryl hydrochloride
12/03/1998WO1998054135A1 Nitrogenous heterocyclic compounds and hyperlipemia remedy containing the same
12/03/1998WO1998053817A1 Biarylalkanoic acids as cell adhesion inhibitors
12/03/1998CA2291762A1 Biarylalkanoic acids as cell adhesion inhibitors
12/03/1998CA2291630A1 Nitrogen-containing heterocyclic compounds and therapeutic agents for hyperlipidemia comprising the same
12/02/1998EP0880893A1 Method for controlling algae
12/02/1998EP0583358B1 Partial liquid breathing of fluorocarbons
12/02/1998CN1200374A Vitronectin receptor antagonists, their prepn. and their use
1 ... 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 ... 119