Patents
Patents for C07D 217 - Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems (11,865)
12/1999
12/21/1999US6004978 Methods of treating cancer with aromatic nitro and nitroso compounds and their metabolites
12/16/1999WO1999064412A1 Tetrahydroisoquinoline derivatives as modulators of dopamine d3 receptors
12/16/1999WO1999064400A1 INHIBITORS OF p38
12/16/1999WO1999064395A1 Heterocyclic amide compounds as cell adhesion inhibitors
12/16/1999WO1999064394A1 Neuropeptide y5 receptor antagonists
12/16/1999WO1999064011A1 Drugs
12/16/1999CA2334814A1 Tetrahydroisoquinoline derivatives as modulators of dopamine d3 receptors
12/15/1999CN1238764A ApoB-secretion/MTP inhibitory amides
12/14/1999US6001851 HIV protease inhibitors
12/14/1999CA2186485C An improved method of synthesis for 6,9-bis((2-aminoethyl)amino)benzo(g)isoquinoline-5,10-dione and its dimaleate salt
12/08/1999EP0961615A1 Antimicrobial agent
12/08/1999CN1237961A Aminoguanidines and alkoxyguanidines as protease inhibitors
12/07/1999US5998624 Haloisoquinoline carboxamide
12/07/1999US5998399 Hypotensive agents
12/07/1999US5998087 Preferably a graphic arts recording material. high gradation and excellent hard dot quality are obtained.
12/02/1999WO1999061424A1 Conformationally constrained amino acid compounds having affinity for the alpha2delta subunit of a calcium channel
12/02/1999WO1999061423A1 New heterocyclically substituted amides, their production and their use
12/02/1999WO1999060985A2 Compounds, compositions and methods for treating erectile dysfunction
12/01/1999EP0960108A1 Matrix metalloproteinase inhibitors
12/01/1999EP0828716B1 Trifluortetrahydro-isoquinoline derivatives and the use thereof in liquid crystalline mixtures
12/01/1999EP0825987B1 1-fluorisoquinoline derivatives and the use thereof in liquid crystalline mixtures
12/01/1999EP0824521B1 1-fluor-6,7-dihydro-5h-isoquinoline-8-one-derivatives and the use thereof in liquid crystalline mixtures
12/01/1999EP0655056B1 Azacyclyl-terminated n-(dihydroxy alkyl)-ethynyl-alanine amides for treatment of hypertension
11/1999
11/30/1999US5994555 Process for the production of a β-amino alcohol
11/30/1999US5994545 Process for producing optically active amides
11/25/1999WO1999059974A1 Tetraisoquinololine derivatives as modulators of dopamine d3 receptors
11/25/1999WO1999059973A1 Carboxamide compounds, compositions, and methods for inhibiting parp activity
11/25/1999WO1999059570A1 Protease inhibitors
11/25/1999WO1999059499A2 Serotonergic 5ht7 receptor compounds for treating ocular and cns disorders
11/25/1999DE3943678C2 New isoquinoline:sulphonamide and naphthalene:sulphonamide cpds.
11/25/1999CA2332505A1 Serotonergic 5ht7 receptor compounds for treating ocular and cns disorders
11/25/1999CA2332492A1 Protease inhibitors
11/25/1999CA2332316A1 Tetraisoquinololine derivatives as modulators of dopamine d3 receptors
11/25/1999CA2332279A1 Carboxamide compounds, compositions, and methods for inhibiting parp activity
11/24/1999EP0957913A1 N-linked sulfonamides of heterocyclic thioesters
11/24/1999CN1046713C Tetrahydroisoquinoline compound, pharmaceutical composition containing them and its producing method and use
11/23/1999US5990311 Producing 5,6-dimethyl-2-(4-fluorophenylamino)-4-(1-methyl)-1,2,3,4 -tetrahydroisoquinolin-2-yl)pyrimidine by condensing 5,6-dimethyl-2-(4-fluorophenylamino)pyrimidine with 1-methyl-1,2,3,4-tetrahydroisoquinoline
11/23/1999US5990158 Carboxylic acid derivatives, method of manufacturing the same and therapeutic agents containing these compounds
11/18/1999WO1999058531A1 Novel substituted aryl hydroxamic acids as metalloproteinase inhibitors
11/18/1999WO1999058125A1 Metabolites of ecteinascidin 743
11/18/1999CA2330108A1 Novel substituted aryl hydroxamic acids as metalloproteinase inhibitors
11/17/1999EP0957093A2 Retrovial protease inhibitors
11/17/1999EP0957092A1 Ring-closed dihydropyridines and their use in the preparation of pharmaceutical compositions
11/16/1999US5985870 Sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors
11/16/1999CA1340821C Heterocyclic compounds and anticancer-drug reinforcing agents containing them as effective components
11/11/1999WO1999057221A1 Compounds for organic el element and organic el element
11/11/1999WO1999057220A1 Compounds for organic el devices and organic el devices
11/11/1999WO1999057098A2 Substituted beta-amino acid inhibitors of methionine aminopeptidase-2
11/11/1999WO1999042457A3 Substituted alxoxycarbonyl compounds
11/11/1999CA2329704A1 Substituted beta-amino acid inhibitors of methionine aminopeptidase-2
11/10/1999CN1046269C HIV protease inhibitors
11/09/1999US5981521 Tetrahydroisoquinoline derivatives as LHRH antagonists
11/09/1999US5981435 Methods for controlling algae
11/09/1999CA2102321C Partial liquid breathing of fluorocarbons
11/04/1999WO1999055679A1 Isoquinoline compound melanocortin receptor ligands and methods of using same
11/04/1999WO1999055661A1 Aminomethyl-benzoic ester derivatives as tryptase inhibitors
11/02/1999US5977388 Compounds useful for preparing an α,α'-diaminoalcohol
10/1999
10/28/1999WO1999054320A1 Novel heterocyclically substituted amides with cysteine protease-inhibiting effect
10/28/1999WO1999054313A1 Bicyclic compounds having an anti-thrombitic effect
10/28/1999WO1999054306A1 Isoquinolinesulfonamide derivatives and drugs containing the same as the active ingredient
10/28/1999CA2328720A1 Novel heterocyclically substituted amides with cysteine protease-inhibiting effect
10/28/1999CA2327276A1 Isoquinolinesulfonamide derivatives and drugs containing the same as the active ingredient
10/28/1999CA2323606A1 Bicyclic compounds having an anti-thrombitic effect
10/27/1999EP0824522B1 1,8-difluorisoquinoline derivatives and the use thereof in liquid crystalline mixtures
10/27/1999EP0584088B1 Substituted guanidines and derivatives thereof as modulators of neurotransmitter release and novel methodology for identifying neurotransmitter release blockers
10/26/1999US5973188 Anticoagulant; prevention cell, protein binding
10/21/1999WO1999037623A3 Sulphonamide derivatives for treatment of cns disorders
10/21/1999WO1999026927A3 Metabotropic glutamate receptor antagonists for treating central nervous system diseases
10/21/1999DE19816983A1 New bicyclic heteroaromatic amidine or nitrile compounds, used as thrombin inhibitors, antithrombotic agents or intermediates
10/20/1999CN1232455A Intermediates for making HIV-protease inhibitors and method of making HIV-protease inhibitors
10/19/1999US5969175 Purification of nitrile
10/19/1999US5968985 Benzoylguanidine derivatives as medicaments
10/19/1999US5968950 Treatment of hypertriglyceridemia with decreasing apo b secretion for treatment of atheriosclerosis, pancreatitis, obesity or diabetes
10/19/1999US5968949 Substituted hydroisoquinoline derivatives and their use as pharmaceuticals
10/19/1999US5968948 Annelated dihydropyridines and the use thereof for preparing pharmaceutical preparations
10/14/1999WO1999051572A1 Sulfonamide derivatives
10/14/1999WO1999051571A1 Benzamide and sulfonamide substituted aminoguanidines and alkoxyguanidines as protease inhibitors
10/14/1999WO1999051241A1 Calcilytic compounds and method of use
10/14/1999CA2327290A1 Sulfonamide derivatives
10/14/1999CA2327188A1 Calcilytic compounds and method of use
10/14/1999CA2326759A1 Benzamide and sulfonamide substituted aminoguanidines and alkoxyguanidines as protease inhibitors
10/13/1999EP0783486B1 Novel prostaglandin synthase inhibitors
10/13/1999CN1231660A Pictet-spengler reaction for the synthesis of tetrahydroisoquinolines and related heterocyclic compounds
10/12/1999US5965733 Process for manufacturing an αα'-diaminoalcohol
10/12/1999US5965539 Peptidomimetics; anti-cancer drugs
10/07/1999WO1999050237A1 Sulfonamide derivatives and drugs containing the same as the active ingredient
10/07/1999CA2325997A1 Sulfonamide derivatives and drugs containing the same as the active ingredient
10/06/1999EP0946520A1 Isoquinolinamine and phthalazinamine derivatives which interact with crf receptors
10/06/1999EP0946502A1 Sulfonamide interleukin-beta converting enzyme inhibitors
10/06/1999EP0824520B1 1-fluor-5,6,7,8-tetrahydroisoquinoline derivatives and their use in liquid crystal mixtures
10/06/1999CN1230951A Hetaroyl cyclohexanedione derivatives with herbicidal effect
10/05/1999US5962725 Chemical intermediate; blocks reproduction of virus
10/05/1999US5962506 Glycol and hydroxyphosphonate peptidomimetics as inhibitors of aspartyl proteases
10/05/1999US5962471 Substituted 6- and 7-aminotetrahydroisoquinolinecarboxylic acids
10/05/1999US5962469 Cyclic nitrones
09/1999
09/30/1999WO1999048492A1 Amide derivatives and nociceptin antagonists
09/30/1999CA2325638A1 Amide derivatives and nociceptin antagonists
09/29/1999EP0944602A1 Apo b-secretion/mtp inhibitory amides
09/29/1999EP0944590A2 Aminoguanidines and alkoxyguanidines as protease inhibitors
09/29/1999CN1230110A Cell adhesion inhibitors
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