Patents
Patents for C07D 217 - Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems (11,865)
06/1999
06/04/1999CA2255180A1 N-(4-carbamimido-phenyl)-phenylglycinamid derivatives
06/03/1999WO1999026927A2 Metabotropic glutamate receptor antagonists for treating central nervous system diseases
06/03/1999WO1999026921A1 SUBSTITUTED β-ALANINE DERIVATIVES AS CELL ADHESION INHIBITORS
06/03/1999WO1999005096A3 Urokinase inhibitors
06/03/1999WO1999002502A3 Sulphonamide derivatives being 5-ht6 receptor antagonists and process for their preparation
06/03/1999CA2311131A1 Metabotropic glutamate receptor antagonists for treating central nervous system diseases
06/03/1999CA2309341A1 Substituted .beta.-alanine derivatives as cell adhesion inhibitors
06/02/1999EP0918761A1 Certain amido- and amino-substituted benzylamine derivatives; a new class of neuropeptite y1 specific ligands
06/02/1999CN1218473A Naphthyridine derivatives and their analogues inhibiting cytomegalovirus
06/02/1999CN1218465A 2,4-diaminopyrimidine derivatives
06/02/1999CN1218454A Preparation of 1-alkoxycarbonyl-3-phenylpropyl derivatives
06/01/1999CA1340570C Process for synthesizing n-alkylated amino-acides and the esters thereof. their use for synthesizing carboxyalkyl dipeptides
05/1999
05/27/1999WO1999025709A1 Isoquinoline derivatives and their therapeutical use
05/27/1999CA2309905A1 Isoquinoline derivatives and their therapeutical use
05/26/1999EP0917530A1 Tetrahydroisoquinoline derivatives as modulators of dopamine d3 receptors
05/26/1999EP0917462A1 Cell adhesion inhibitors
05/26/1999CN1217722A Process for preparing pyrimidine derivatives
05/19/1999EP0915879A1 Novel compounds
05/19/1999EP0690851B1 Guanidine derivatives useful in therapy
05/18/1999US5905155 Process for the preparation of an optically pure tetrahydroquinoline carboxylic acid
05/18/1999US5905077 Inhibitors of HIV protease useful for the treatment of AIDS
05/18/1999US5904877 Trifluoratetrahydroisoquinoline derivatives, and the use thereof in liquid-crystalline mixtures
05/12/1999EP0914605A1 Molecular model for vla-4 inhibitors
05/12/1999EP0914332A1 Isoquinolines useful as analgesics
05/12/1999EP0914130A2 Novel anti-viral compounds
05/12/1999EP0583433B1 Diphosphine ligands
05/06/1999WO1999021848A2 Novel 1-(n'-(arylalkylaminoalkyl))aminoisoindoles; a new class of dopamine receptor subtype specific ligands
05/06/1999WO1999021836A1 Substituted isoquinoline derivatives and their use as anticonvulsants
05/06/1999WO1999021834A1 Heteroaryl diazacycloalkanes as cholinergic ligands at nicotinic acetylcholine receptors
05/06/1999WO1999021557A1 Antagonists of gonadotropin releasing hormone
05/06/1999DE19748433A1 1-Fluoro-isoquinoline-8-carbonitrile derivatives, used as components of liquid crystal mixtures
05/06/1999CA2308069A1 Antagonists of gonadotropin releasing hormone
05/06/1999CA2307030A1 Substituted isoquinoline derivatives and their use as anticonvulsants
05/05/1999CN1215990A IL-8 receptor antagonists
04/1999
04/29/1999WO1999020608A1 Isoquinolines as urokinase inhibitors
04/29/1999WO1999020599A1 Pharmaceutically active compounds and methods of use
04/29/1999WO1999004775A9 Method of treating dopaminergic and gaba-nergic disorders
04/29/1999CA2307597A1 Pharmaceutically active compounds and methods of use
04/28/1999EP0911340A2 Substituted Isoquinolin-3-Carboxyamides, their preparation and medical use
04/28/1999EP0910564A1 D-amino acid derived inhibitors of cysteine and serine proteases
04/28/1999EP0910562A2 A method for the preparation of tertiary amines, a compound useful therefor and alpha-2-receptor active tetrahydroisoquinoline derivatives
04/28/1999EP0787721B1 4a-ARYLDECAHYDROISOQUINOLINE COMPOUNDS AND MEDICINAL USES THEREOF
04/22/1999WO1999018960A1 Novel combination
04/22/1999WO1999018941A2 Ih-MODULATORS
04/22/1999WO1999011624B1 Oxo-substituted compounds, process of making, and compositions and methods for inhibiting parp activity
04/22/1999WO1999002146A8 Amino acid derivatives
04/22/1999CA2305180A1 Ih-modulators
04/22/1999CA2305141A1 Novel combination
04/21/1999EP0695184B1 Hiv protease inhibitors
04/21/1999EP0579797B1 Diphosphine ligands
04/20/1999CA2250664A1 Substituted isoquinoline-3-carboxamides, their preparation and their use as pharmaceuticals
04/15/1999WO1999018077A1 Fused pyridine derivatives
04/15/1999WO1999017776A1 Novel cycloalkenyl substituted compounds
04/15/1999WO1999002153A9 Glycol and hydroxyphosphonate peptidomimetics as inhibitors of aspartyl proteases
04/15/1999CA2306077A1 Novel cycloalkenyl substituted compounds
04/14/1999EP0908178A1 Partial liquid breathing of fluorocarbons
04/14/1999CN1214043A Benzyl(idene)-lactam derivatives, their prepn. and their use as selective (ant) agaonists of 5-ht1A-and/or 5-ht1D receptors
04/08/1999WO1999016752A1 β3-ADRENORECEPTOR AGONISTS, AGONIST COMPOSITIONS AND METHODS OF USING
04/08/1999WO1999016747A1 Sulfonyl derivatives
04/08/1999WO1999016746A1 Aminoalkylphenol derivatives and related compounds
04/08/1999CA2304285A1 Sulfonyl derivatives
04/07/1999EP0906283A1 Substituted benzamide derivatives and their use as anticonvulsants
04/07/1999EP0906091A1 Amidinohydrazones as protease inhibitors
04/06/1999US5892044 Asymmetrically hydrogenating 1-(p-methoxybenzyl)-3,4,5,6,7,8-hexahydroisoquinoline or salt thereof in presence of catalytically effective optically active iridium-phosphine complex
04/06/1999US5891909 Amidinohydrazones as protease inhibitors
04/01/1999WO1999015508A1 Vitronectin receptor antagonists
04/01/1999WO1999015490A1 C3a receptor ligands
04/01/1999CA2303883A1 C3a receptor ligands
04/01/1999CA2303487A1 Vitronectin receptor antagonists
03/1999
03/31/1999EP0904079A1 Antidiabetic agents
03/30/1999US5889163 Method for producing azo dye compounds
03/30/1999US5889042 Method of treating diseases and conditions with estrogen agonists and antagonists
03/30/1999US5889018 Heterocyclic compounds, pharmaceutical compositions comprising them and process for the preparation thereof
03/25/1999WO1999014198A1 Separation of enantiomers of octahydroisoquinoline
03/25/1999WO1999014197A1 Substituted isoquinolines as anticonvulsivants
03/25/1999CA2303972A1 Separation of enantiomers of octahydroisoquinoline
03/25/1999CA2303777A1 Substituted isoquinolines as anticonvulsivants
03/24/1999EP0903337A1 Process for the preparation of 1-alkoxycarbonyl-3-phenylpropyl derivatives
03/24/1999EP0902781A1 Preparation of (s)-decahydroisoquinoline-3-carboxylic acid t-butylamide
03/24/1999EP0563128B1 New 3,4-dihydroisoquinoline derivates and new pharmaceutical use of carbocyclically and heterocyclically annulated dihydropyridines
03/24/1999CN1211990A Isoquinolines useful as analgesics
03/23/1999US5886044 IL-8 receptor antagonists
03/23/1999US5885985 Antiinflammatory agents
03/18/1999WO1998058911A3 Prostaglandin agonists
03/17/1999EP0901996A1 Process for producing optically active amines
03/17/1999EP0901488A1 2,4-diaminopyrimidine derivatives
03/17/1999EP0901465A1 Compounds with anti-inflammatory and immunosuppressive activities
03/17/1999EP0655058B1 Pyridinyl/quinolinyl-terminated alkylamino ethynyl alanine amino diol compounds for treatment of hypertension
03/17/1999CN1211252A Coralyne analogs as topoisomerase inhibitors
03/16/1999US5883257 N-piperidinyl- and N-tetrahydropyridinyl-2-anthracenecarboxamides: dopamine receptor subtype specific ligands
03/16/1999US5883125 Benzyloxy substituted aromatics and their use as fungicides and insecticides
03/16/1999US5883099 Treatment of athersclerosis, pancreatitis obesity or hyperglycemia
03/16/1999US5882546 1,8-Difluorisoquinoline derivatives and the use thereof in liquid crystalline mixtures
03/11/1999WO1999011658A1 Meta-benzamidine derivatives as serin protease inhibitors
03/11/1999WO1999011657A1 1-amino-7-isoquinoline derivatives as serine protease inhibitors
03/11/1999WO1999011649A2 Parp inhibitors, pharmaceutical compositions comprising same, and methods of using same
03/11/1999WO1999011628A1 Alkoxy-substituted compounds, methods, and compositions for inhi biting parp activity
03/11/1999WO1999011624A1 Oxo-substituted compounds, process of making, and compositions and methods for inhibiting parp activity
03/11/1999WO1999011623A1 Thioalkyl compounds, methods, and compositions for inhibiting parp activity
03/11/1999WO1999011622A1 Amino-substituted compounds, methods, and compositions for inhibiting parp activity
1 ... 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 ... 119