Patents
Patents for C07D 217 - Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems (11,865)
04/2008
04/16/2008EP1910277A1 Quadratic acid derivatives in the form of a protein kinase inhibitors
04/16/2008CN100381424C Biaryl sulfonamides and methods for using same
04/15/2008US7358359 Antibacterial agents
04/15/2008US7358220 Alkoxylated polyol containing bleach activating terminating functional groups
04/10/2008WO2008041087A1 An improved process for preparation of amorphous nelfinavir mesylate
04/10/2008WO2008003702A3 Fused bicyclic compounds interacting with the histamine h4 receptor
04/10/2008WO2007144652A3 Parp inhibitors
04/10/2008US20080085917 7-(2-(4-(3-trifluoromethyl-phenyl)-1,2,3,6-tetrahydropyrid-1-yl)ethyl)isoquinoline besylate salt, preparation and therapeutic use thereof
04/10/2008US20080085894 Alpha-(n-sulfonamido)acetamide derivatives as beta-amyloid inhibitors
04/10/2008US20080085893 N-Hydroxy (2S)-2-hydroxy phenyl or heteroaryl sulfonamide derivatives; for example, N-Hydroxy (2S)-2-hydroxy-3-{N-[4-(4- chlorophenoxy)phenyl], N- methanesulfonylamino}propionamide; for treating disorders related to matrix metalloproteases, particularly useful for treating strokes;
04/10/2008US20080085890 Substituted isoquinoline-1,3(2H,4H)-diones, 1-thioxo-1,4-dihydro-2H-isoquinoline-3-ones and 1,4-dihydro-3 (2H)-isoquinolones and methods of use thereof
04/09/2008EP1906962A2 Octahydroisoquinoline compounds as opioid receptor modulators
04/08/2008US7354944 protein kinase B inhibitors; abnormal cell growth, cancer, inflammation, and metabolic disordersp; 3-(3-Fluoro-phenyl)-N-[5-(3-methyl-1H-indazol-5-yl)-[1,3,4]thiadiazol-2-yl]-propane-1,2-diamine
04/03/2008WO2008039645A1 Compounds which modulate the cb2 receptor
04/03/2008WO2008037482A1 Biofilm-inhibiting effect and anti-infective activity of n,c-linked arylisoquinolines and the use thereof
04/03/2008WO2008014199A3 Sulfonyl compounds which modulate the cb2 receptor
04/03/2008US20080081802 Thiazolyl-Dihydro-Indazole
04/03/2008CA2664310A1 Compounds which modulate the cb2 receptor
04/02/2008CN101153023A Tetrahydrochysene isoquinoline derivant, its producing method and uses of the same
04/02/2008CN101153022A Isoquinolinium compound, producing method and application of its salt
04/02/2008CN101153021A Isoquinolinium compound, producing method and application of its salt
04/01/2008US7351825 4-[5-((1S,2R)-1-Carboxy-2-phenyl-cyclopropylsulfamoyl)-thiophen-2-yl]-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester; aggrecanase and matrix metalloproteinase (with zinc in the catalytic active center) (MMP) inhibitor; antiarthritic agent: osteoarthritis, rheumatoid arthritis
04/01/2008US7351703 Which modulate the endogenous production of cyclic guanosine monophosphate (cGMP); for therapy and prophylaxis of cardiovascular disorders such as high blood pressure, angina pectoris, cardiac insufficency, thromboses, and/or atherosclerosis
03/2008
03/27/2008WO2008036172A1 Preparation of substituted morphinan-6-ones and salts and intermediates thereof
03/27/2008US20080076784 Bicyclic, Nitrogen-Containing Heterocycles and Aromatase Inhibitors
03/27/2008CA2663909A1 Preparation of substituted morphinan-6-ones and salts and intermediates thereof
03/26/2008CN101151250A Processes for preparing morphinans and intermediates thereof
03/26/2008CN100377004C Image forming material and ammonium compound
03/25/2008US7348427 Substituted with an amido heterocylic groups; infection by Gram-positive bacteria.
03/25/2008US7348359 Retinoid X receptor modulators
03/25/2008CA2268709C Hiv protease inhibitors
03/20/2008WO2008033757A2 2-(1-oxo-1h-isoquinolin-2-yl) acetamide derivatives
03/20/2008WO2008031509A1 ISOSERINE DERIVATIVES FOR USE AS COAGULATION FACTOR IXa INHIBITORS
03/20/2008WO2008031508A1 TARTRATE DERIVATIVES FOR USE AS COAGULATION FACTOR IXa INHIBITORS
03/20/2008WO2008005910A3 Pyridone/hydroxypyridine 11-beta hydroxysteroid dehydrogenase type i inhibitors
03/20/2008US20080070935 Isoquinoline, Quinazoline and Phthalazine Derivatives
03/20/2008CA2663544A1 Isoserine derivatives for use as coagulation factor ixa inhibitors
03/20/2008CA2663543A1 Tartrate derivatives for use as coagulation factor ixa inhibitors
03/20/2008CA2663193A1 2-(1-oxo-1h-isoquinolin-2-yl)acetamide derivatives
03/20/2008CA2663161A1 Quinazolinone and isoquinolinone acetamide derivatives
03/19/2008EP1899322A1 Isoquinoline derivatives as inhibitors of rho-kinase
03/19/2008EP1363630B1 Kappa opioid receptor ligands
03/19/2008EP1283711B1 Peptide deformylase inhibitors
03/19/2008CN101146808A Phenyl methanone derivatives and their use as glycine transporter 1 inhibitors
03/19/2008CN101146779A Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents
03/19/2008CN101143846A Metal salt of quinaprilat
03/18/2008CA2293705C Process for obtaining quinapryl hydrochloride and solvates useful for isolating and purifying quinapryl hydrochloride
03/13/2008WO2008029199A1 Positively charged water-soluble prodrugs of n-arylanthranilic acids with very fast skin penetration rate
03/13/2008WO2007146838A3 Substituted phenyl acetic acids as dp-2 antagonists
03/13/2008US20080064714 Novel Pyrrolodihydroisoquinolines
03/13/2008US20080064690 Neuropathic or inflammatory pain relief; inhibiting ion flux through channel including PN3 subunit; potency
03/13/2008US20080064687 Vanilloid receptor modulators; analgesic, antiinflammatory and antiulcer effects; such as 1-(1H-indol-5-ylmethyl)-3-phenethylthiourea
03/13/2008US20080064678 N-tert-Butyl-2-[3-(4-fluoro-3-methoxyphenyl)-1-oxo-7-(3-pyrrolidin-1-ylpropoxy)-1H-isoquinolin-2-yl]acetamide; 2-[3-(3-Chlorophenyl)-7-((S)-2-methyl-3-pyrrolidin-1-ylpropoxy)-1-oxo-1H-isoquinolin-2-yl]-N-isopropylacetamide; antidepressants; hypothalamo-pituitary-adrenal axis modulators
03/12/2008EP1897881A2 Compounds useful for the treatment of obesity, type II diabetes and CNS disorders
03/12/2008EP1897876A2 Compounds useful for the treatment of obesity, type II diabetes and CNS disorders
03/12/2008EP1896561A2 Process of producing bleach boosters
03/12/2008EP1896420A1 Process of producing bleach boosters
03/12/2008EP1896419A1 3,4-dihydroisoquinolinium salt derivatives
03/12/2008EP1763515B1 4-trifluoromethoxyphenoxybenzol-4'-sulfonic acids, method for the production and use thereof in medicaments
03/12/2008EP1495009B1 Cyanamides useful as reversible inhibitors of cysteine proteases
03/12/2008CN101142187A 离子型有机化合物 Ionic organic compounds
03/11/2008US7342013 Benzamides and related inhibitors of factor Xa
03/06/2008WO2008026704A1 Isoquinoline derivative
03/06/2008WO2008025240A1 Composition comprising amino heterocyclic compound for hair dyeing and dyeing method
03/06/2008US20080058335 Pain, inflammatory or immune disorders, neurological disorders, cancers of the immune system, respiratory disorders, cardiovascular disorders, neuroprotection; e.g. 5-chloro-N-[(2Z)-5-(1-hydroxy-1-methylethyl)-3-[((cis)-3-methoxycyclobutyl)methyl]-4-methyl-1,3-thiazol-2(3H)-ylidene]-2-methoxybenzamide
03/06/2008US20080058328 Substituted 4-phenyltetrahydroisoquinolines, pharmaceuitcal compositions comprising them and therapeutic methods for their use
03/05/2008EP1893573A1 Inhibitors of hcv replication
03/05/2008CN101137650A 2-[(isoquinolin-3-carbonyl)amino]-propionic acid derivatives as inhibitors of factors xi and ix for the treatment of thrombosis
02/2008
02/28/2008WO2008023357A1 Heterocyclic derivatives binding to the peripheral-type benzodiazepine receptor (pbr)
02/28/2008CA2661307A1 Heterocyclic derivatives binding to the peripheral-type benzodiazepine receptor (pbr)
02/27/2008EP1399423B9 Anthranilic acid amides with a heteroarylsulfonyl side chain, method for the production thereof, use thereof as a medicament or diagnostic agent and pharmaceutical preparations containing said compounds
02/27/2008EP1248612B1 Novel compounds and compositions as protease inhibitors
02/27/2008EP1246806B1 Arly- and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine and serotonin
02/27/2008CN101133060A Enzyme inhibitors
02/27/2008CN100371318C Aryl sulfonamides and analogues thereof and their use in the treatment of neurodegenerative diseases
02/26/2008US7335678 Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1(VR1) receptor
02/26/2008US7335659 Substituted 10-aryl-11H-benzo[b]fluorenes and 7-aryl-5, 6-dihydro-benzo[a]anthracenes for selective effects on estrogen receptors
02/21/2008WO2008020081A1 6-substituted isoquinoline derivatives as rock-1 inhibitors
02/21/2008US20080045566 6-substituted isoquinoline derivatives
02/21/2008US20080045546 Tetradydro-Naphthalene And Urea Derivatives
02/21/2008US20080045534 Derivatives of 1,3-diamino benzene as potassium channel modulators
02/21/2008US20080045530 Organic Compounds and Their Uses
02/21/2008US20080045516 Viral Polymerase Inhibitors
02/21/2008CA2660911A1 Thiourea compounds
02/21/2008CA2660489A1 6-substituted isoquinoline derivatives as rock-1 inhibitors
02/20/2008EP1889837A1 VR1 vanilloid receptor antagonists with a iononic substructure
02/20/2008EP1888566A1 2-[(isoquinolin-3-carbonyl)amino]-propionic acid derivatives as inhibitors of factors xi and ix for the treatment of thrombosis
02/20/2008EP1888518A1 Novel 8-sulfonyl-3 aminosubstituted chroman or tetrahydronaphtalene derivatives modulating the 5ht6 receptor
02/20/2008EP1697304B1 Peroxisome proliferator activated receptor modulators
02/20/2008EP1427417B1 3-substituted 6,7-dihydroxytetrahydroisoquinoline derivatives for use as antibacterial agents
02/20/2008CN101128434A Amide derivatives
02/20/2008CN101128433A Isoquinoline derivatives as calpain inhibitors
02/20/2008CN101128432A Tetrahydroisoquinoline compounds for treatment of cns disorders
02/19/2008US7332524 Adamantyl acetamides as 11-beta hydroxysteroid dehydrogenase inhibitors
02/19/2008US7332511 Vanilloid receptor ligands and their use in treatments
02/19/2008US7332233 Multilayer; charge generating compound, charge transfer compound; blue phosphorescence
02/14/2008WO2008019356A2 Process for the preparation of substituted-1,2,3,4-tetrahydroisoquinoline derivates
02/14/2008WO2008018544A1 Sulfonamide compound or salt thereof
02/14/2008WO2008017588A1 Verapamil analogues with inhibition activity on abc (atp binding cassette) cell extrusion pumps
02/14/2008US20080039494 8-Phenyl-5,6,7,8-Hydroquinoline Tachykinin Receptor Antagonists
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