Patents
Sitemap › C07 - Organic chemistry › C07D - Heterocyclic compounds › C07D 217 - Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
Patents for C07D 217 - Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems (11,865)
11/2008
11/05/2008CN101300241A Piperazine derivatives as antimalarial agents
11/04/2008US7446115 To treat pain, drug addiction, or tinnitus; selectively inhibit sodium or calcium ion channels and agonize or antagonize mu -opioid receptors; N-Benzyl-N-(2-dimethylamino-ethyl)-2-(S)-[3-(4-fluorophenyl)-ureido]-3-methyl-butyramide
11/04/2008US7446109 Carbonylamino-derivatives as novel inhibitors of histone deacetylase
11/04/2008US7446103 N-[4-(3-Piperidin-1-ylpropoxy)-benzoyl]-5-fluoroisoindoline; Alzheimer's disease; cognition enhancers; amidation
10/2008
10/30/2008WO2008130319A2 Novel n-tetrahydronaphtalene or n-chromane carboxamide derivatives for the treatment of pain
10/30/2008WO2008129276A1 Disulfonamides useful in the treatment of inflammation
10/30/2008WO2008129029A1 Phthalazine and isoquinoline derivatives with slp receptor modulating activities
10/30/2008WO2008022204A3 Thiourea compounds
10/30/2008US20080269296 Diaryl ethers as opioid receptor antagonists
10/30/2008US20080269221 Antibacterial agents
10/30/2008US20080269199 Therapy for obesity, diabetes, sleep disorders, Alzheimer's disease, Parkinson's disease; attention deficit disorders; antiepileptic agents; schizophrenia; antidepressants; anxiolytic agents
10/30/2008US20080269197 antipsychotic agents; phenylsulfonyl compounds; 7-Methoxy-8-(3-phenoxy-benzenesulfonyl)-2,3,4,5-tetrahydro-1H-3-benzazepine; schizophrenia
10/30/2008CA2684965A1 Phthalazine and isoquinoline derivatives with s1p receptor modulating activities
10/29/2008EP1985615A1 Method for producing benzazepinone
10/29/2008EP1984358A1 Method for resolving enantiomers from racemic mixture having chiral carbon in alpha position of nitrogen
10/29/2008EP1216228B1 BENZAMIDES AND RELATED INHIBITORS OF FACTOR Xa
10/28/2008USRE40558 Peroxisome proliferator-activated receptors agonists/ antagonists; 2-methyl-6-[3-(quinolin-2-ylmethoxy)-propoxymethyl]-benzoic acid; eating diorders; physiological detrimental blood level of insulin, glucose, free fatty acids, or triglycerides; hyperlipemia; atherosclerosis; antidiabetic agent
10/28/2008US7442794 Stereoisomers ; reacting with Lewis acid; purification
10/28/2008US7442710 Substituted phenyl methanones
10/28/2008US7442448 Phenyl pyridine-iridium metal complex compounds for organic electroluminescent device and organic electroluminescent device using thereof
10/28/2008US7442447 Binaphthol based chromophores for the fabrication of blue organic light emitting diodes
10/23/2008WO2008021849A3 Novel compounds as antagonists or inverse agonists at opioid receptors
10/23/2008US20080262231 Cyclization of a bicyclic ketone; water scavenger adjuvant; chemical intermediates for analgesics
10/23/2008US20080261994 4-[5-((1S,2R)-1-Carboxy-2-phenyl-cyclopropylsulfamoyl)-thiophen-2-yl]-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester; aggrecanase and matrix metalloproteinase (with zinc in the catalytic active center) inhibitor; antiarthritic agent: osteoarthritis, rheumatoid arthritis
10/23/2008US20080261272 reporter system reflecting the transport process that transports GPI-anchored proteins to the cell wall was constructed and compounds inhibiting this process were discovered; antifungal agents; inhibiting expression of cell wall glycoproteins and preventing pathogens from showing pathogenicity; DNA
10/22/2008EP1658269B1 Fused compounds that inhibit vanilloid receptor subtype 1 (vr1) receptor
10/22/2008EP1417190B1 Substituted piperazines as modulators of the melanocortin receptor
10/21/2008US7439363 Substituted indazoly(indoly)maleimide derivatives as kinase inhibitors
10/21/2008US7439257 Aryloxyalkylcarbamate-type derivatives, preparation method thereof and use of same in therapeutics
10/21/2008US7439254 Compounds, compositions, and methods
10/21/2008US7439242 PPARγ modulators
10/16/2008WO2008123582A1 Tetrahydroisoquinoline compound
10/16/2008WO2008123207A1 Ornithine derivative
10/16/2008WO2008122765A1 New compounds and their uses 707
10/16/2008US20080255221 Novel hydroxamates as therapeutic agents
10/16/2008US20080255214 Novel hydroxamates as therapeutic agents
10/16/2008US20080255188 Muscarinic Receptor Antagonists
10/16/2008US20080255154 Cycloalkylcarbonyl-3H-spiro[2-benzofuran-1,3'-pyrrolidin]-3-ones: N-methyl-5-[4-(1-{[3-oxo-1'H,3H-spiro[2-benzofuran-1,3'-pyrrolidin]-1'-yl]carbonyl}cyclopropyl)phenyl]pyridine-2-carboxamide; 11- beta hydroxyl steroid dehydrogenase type 1 inhibitors; mineralcorticoid receptor antagonists; diabetes
10/16/2008US20080255152 Diaryl ethers as opioid receptor antagonists
10/16/2008US20080255109 Antigonadotrophins; breast and prostate cancer, endometriosis, benign prostate hyperplasia; regulation of fertility; 4-(3-Chloro-4-{{(4-chloro-benzenesulfonyl)-methyl-amino]-methyl}-thiophene-2-carbonyl)-3,4-dihydro-2H-benzo[1,4]oxazine-2carboxylic acid (3-methyl-[1,2,4]oxadiazol-5-ylmethyl)-amide
10/16/2008US20080255095 Benzylamine analogues
10/16/2008CA2681861A1 Ornithine derivative
10/16/2008CA2681221A1 Isoquinolinone derivatives and their uses
10/15/2008EP1660455B1 Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (vr1) receptor
10/14/2008US7435823 2,3-Dihydro-4H-1,4-benzoxazine derivatives containing an optionally fused pyridine or pyrimidine ring; 7-((6,7-bis(methyloxy)-4-quinolinyl)oxy)-N-phenyl-2,3-dihydro-4H-1,4-benzoxazine-4-carboxamide; kinase inhibitors; inflammation, angiogenesis and cancer
10/14/2008US7435815 Sulfonylamino-acetic acid derivatives
10/14/2008US7435729 using estrogen antagonist ; anticancer agents
10/09/2008WO2008073390A3 Preparation of 3,4-dihydroisoquinolines from an acid and an amine
10/08/2008EP1976840A1 Cyclohexyl piperazinyl methanone derivatives and their use as histamine h3 receptor modulators
10/08/2008CN101282935A Isoquinolines derivatives as IGF-1R inhibitors
10/07/2008US7432281 4-(2,2-dichloro)-N-(quinolin-3-yl)benzamide; (1R,2R)2-methyl-N-(quinolin-3-yl)-4-(2-(trifluoromethyl)cyclopropyl)benzamide; inflammation-related conditions in mammals, arthritis, Parkinson's/Alzheimer's diseases, stroke, asthma; acute/chronic or neuropathic pain; VR1 agonist/antagonist
10/02/2008WO2008117861A1 Intraocular pressure lowering agents containing phenylenediamine derivatives as the active ingredient
10/02/2008WO2008117271A1 (1r,1'r)-atracurium salts separation process
10/02/2008US20080242861 Synthesis of amino-protected cyclohexane-1,4-diyldimethanamine and its derivatives
10/02/2008US20080242699 Cyclohexylamin isoquinolone derivatives
10/02/2008US20080242698 Antiepilrptic agents; antiischemic agents; vision defects; skin disorders; muscular disorders; anticonvulsants;analgesics; Parkinson's disease; huntington's disease; amyotrophic lateral sclerosis; multiple sclerosis
10/02/2008CA2681060A1 (1r,1'r)-atracurium salts separation process
10/01/2008CN101277939A Acyclic ikur inhibitors
10/01/2008CN100422156C Isoquinolinium compound, producing method and application of its salt
09/2008
09/30/2008US7429667 suc as 5-[4-(2,5-Dichloro-phenoxy)-3-fluoro-phenylamino]-3-hydroxy-N-isopropyl-isothiazole-4-carboxamidine; anticarcinogenic agent
09/30/2008US7429664 Indazoles, benzothiazoles, and benzoisothiazoles, and preparation and uses thereof
09/30/2008US7429586 Non-imidazole aryloxyalkylamines
09/25/2008WO2008097428A3 Compounds and compositions as modulators of gpr119 activity
09/25/2008WO2008073389A3 Preparation of hexahydroisoquinolines from dihydroisoquinolines
09/25/2008US20080234274 Novel Compounds
09/25/2008US20080234268 Effective for prophylaxis and treatment of diseases, such as ("c-Met") hepatocyte growth factor receptor mediated diseases; N-(4-(3-amino-1H-indazol-4-yl)-3-fluorophenyl)-1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide; treatment of neoplasia selected from lung, breast, colon cancer
09/25/2008US20080234266 Squaric Acid Derivatives II
09/25/2008US20080234254 anticarcinogenic agents for treating leukaemia, non-small cell lung cancers, colonic cancers, breast cancers, ovarian cancers, renal cancers and melanoma; in vivo hydrolysable ester or amide; N-(2-amino-phenyl)-4-[1-(3,4-dihydroisoquinolin-2(1H)-ylmethyl)vinyl]benzamide; solid phase synthesis
09/24/2008CN101270086A Sulfonation technique for isoliensinine, arrhythmia resistant function of products produced thereby
09/18/2008WO2007090068A3 Cyanoisoquinoline compounds that stabilize hypoxia inducible factor (hif)
09/18/2008US20080227778 6-Methoxy-3-(methoxymethyl)-2-methyl-4-phenylisoquinolin-1(2H)-one; treat cardiac arrhythmias
09/17/2008EP1968938A1 Substituted propiolic acid amides and their use for producing drugs
09/17/2008EP1392639B1 Pyruvate derivatives
09/17/2008CN101268054A Substituted 4-phenyltetrahydroisoquinolines, process for their preparation, pharmaceutical compositions and therapeutic use
09/17/2008CN101265231A Method for preparing isoquinoline-N-oxide
09/17/2008CN100418955C Novel Benzo-fused heterocycles
09/16/2008US7425631 Compounds and methods of use
09/16/2008US7425563 Excellent poly (ADP-ribose) synthetase inhibitors; various ischemic diseases, inflammatory diseases, neurodegenerative diseases, diabetes, septic shock, cephalic injury; 1,2-Dihydro-4-[4-(dimethylaminomethyl)phenyl]-5-hydroxy-1-oxoisoquinoline
09/12/2008WO2008109336A1 Tetrahydroisoquinoline compounds as modulators of the histamine h3 receptor
09/12/2008WO2008109179A1 Metalloprotease inhibitors containing a squaramide moiety
09/12/2008WO2008109178A1 Metalloprotease inhibitors containing a squaramide moiety
09/12/2008WO2008107887A2 (1r,1'r)-atracurium salts separation process
09/12/2008CA2680277A1 (1r,1'r)-atracurium salts separation process
09/12/2008CA2680177A1 Metalloprotease inhibitors containing a heterocyclic moiety
09/12/2008CA2679735A1 Tetrahydroisoquinoline compounds as modulators of the histamine h3 receptor
09/10/2008EP1965805A1 Urea derivatives useful as calcium receptor modulators
09/09/2008US7423177 Carboxamide derivatives as therapeutic agents
09/09/2008US7423049 e.g., 2-(5-fluoro-2-tolyl)-4-(4-aminocarbonylpiperazinylmethyl)-6-[a-aminocarbonyl-2,6-dichlorobenzyl]pyridine; mitogen-activated protein kinase inhibitor; antiinflammatory agent, autoimmune diseases
09/04/2008US20080214819 Using an isoquinoline compound; alkylation of benzonitrile; reduction ofnitrile to an amine; cyclization
09/04/2008US20080214524 e.g. N-[2-(3-fluorophenyl)ethyl]-N'-isoquinolin-5-ylurea; opioid receptor inhibitor; analgesic, antiinflammatory agent; inflammatory thermal hyperalgesia, urinary incontinence and bladder overactivity
09/04/2008US20080214427 Using polymeric structure of sugar based polyols and other polyols as starting materials for attachment of organic bleach catalysts; benefits in detergents such as soil suspension, bleaching action and increased surfactant availability in the presence of free hardness
09/04/2008US20080214426 Alkoxylated polyol containing bleach activating terminating functional groups
09/04/2008US20080210907 Gelling agent, carbon nanotubes aqueous dispersing agent; simple synthesis from low cost, readily available raw materials; rapid elastic modulus recovery; environmentally friendly
09/03/2008EP1963291A1 Pet radiotracers
09/03/2008EP1963273A2 Substituted isoquinoline-1,3(2h,4h)-diones, 1-thioxo-1,4-dihydro-2h-isoquinoline-3-ones and 1,4-dihydro-3(2h)-isoquinolones and use thereof as kinase inhibitors
09/03/2008EP1761497B1 Azadecalin glucocorticoid receptor modulators
09/03/2008CN101258130A Isoquinolines as igf-1r inhibitors
09/03/2008CN101255135A Optical isomer of tilisolol as well as preparation method and medical use thereof
09/03/2008CN100415737C Indole derivatives useful for treatment of CNS disorders
09/03/2008CN100415718C CASPASE inhibitors and use thereof
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