Patents
Patents for C07D 217 - Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems (11,865)
07/2009
07/14/2009US7560460 2-[(4-Chlorophenyl)methyl]-1-(4- {2-[(cyclopropylmethyl)-(methylsulfonyl)amino]phenyl }-piperazinyl) -4-(2-(1,2,3,4-tetrahydroisoquinolyl))butane-1,4-dione; obesity/dietietics; melanocortin receptor angonists; prophylaxis/treatment of diseases involving activation of the melanocortin recepetors (MCR)
07/09/2009WO2009083903A1 Trisubstituted 3,4-dihydro-1h-isoquinolin compound, process for its preparation, and its use
07/09/2009WO2009083899A2 Process for the preparation of an enantiomeric trisubstituted 3,4-dihydro-isoquinoline derivative
07/09/2009US20090176822 Pyrrolidine inhibitors of iap
07/09/2009US20090176774 Compounds and methods of use
07/09/2009US20090176307 Compounds, Compositions and Methods
07/09/2009CA2709694A1 Trisubstituted 3,4-dihydro-1h-isoquinolin compound, process for its preparation, and its use
07/09/2009CA2708889A1 Process for the preparation of an enantiomeric trisubstituted 3,4-dihydro-isoquinoline derivative
07/08/2009CN101479238A Amine derivative having npyy5 receptor antagonist activity
07/08/2009CN101475530A Method for separating and purifying cisatracurium besylate by preparative liquid chromatography
07/08/2009CN101475529A Mixed solvent crystallization resolution method for tetrahydrochysene isoquinoline racemate
07/08/2009CN100510098C Optically active, heteroaromatic beta-hydroxy esters, processes for their preparation from beta-keto esters and processes for the preparation of these beta-keto esters
07/08/2009CN100509790C Aryl- and heteroarylcarbonylpiperazines and their use for the treatment of benign and malignant oncoses
07/07/2009US7557123 Heterocyclic compound and medicinal use thereof
07/07/2009US7557118 4-Phenyl-6H-(1)Benzopyrano(4',3':4,5)pyrrolo(2,1-a)isoquinolin-6-one's and analogues, optionally mixed with acceptable carriers, excipients or diluents, used for treating multidrug resistant tumors, for inducing apoptosis and as immunology modulators
07/07/2009CA2539969C Process for the preparation of carboxylic acids of nitrogen-containing aromatic heterocyclic compounds
07/02/2009WO2009080728A1 Oxadiazole derivatives active on sphingosine-1-phosphate (sip)
07/02/2009WO2009080724A1 Oxadiazole derivatives active on sphingosine-1-phosphate (s1p)
07/02/2009US20090171090 Method for producing benzazepinone
07/02/2009US20090170881 New inhibitors of histone deacetylase
07/02/2009US20090170838 Bicycloheteroaryl compounds as P2X7 modulators and uses thereof
07/02/2009US20090170836 New inhibitors of histone deacetylase
07/02/2009US20090170824 Diarylsulfones as 5-HT2A Antagonists
07/02/2009CA2710067A1 Oxadiazole derivatives active on sphingosine-1-phosphate (s1p)
07/01/2009EP2074100A1 Biofilm-inhibiting effect and anti-infective activity of n,c-linked arylisoquinolines and the use thereof
07/01/2009EP2074084A1 Compounds which modulate the cb2 receptor
07/01/2009EP1611104B1 Tetrahydroisoquinolyl acetamide derivatives for use as orexin receptor antagonists
07/01/2009CN100506788C Arylalkylcarbamate derivatives production and use thereof in therapy
06/2009
06/30/2009US7553966 Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
06/30/2009US7553852 Caspase inhibitors and uses thereof
06/25/2009US20090163719 Catalyst compositions and their use in the de-enrichment of enantiomerically enriched substrates
06/25/2009US20090163542 5-ht7 receptor antagonists
06/25/2009US20090163496 Antibacterial agents
06/25/2009US20090162694 Electroluminescent iridium compounds having red-orange or red emission and devices made with such compounds
06/25/2009US20090162420 Matrix-Controlled Transdermal System Comprising Salts of ACE Inhibitor Dicarboxylic Acids
06/24/2009CN101466683A Inhibitors of AKT (protein kinase B)
06/24/2009CN100503599C Carbonylamino-derivatives as novel inhibitors of histone deacetylase
06/24/2009CN100503573C Method for generating (3S,4aS,8aS)-decahydroquinoline-3-carboxylic tert-butyl amine catalyzed and hydrogenated by (S)-tetrahydrosquinoline-3-carboxylic tert-butyl amine
06/24/2009CN100503572C Caspase inhibitors and uses thereof
06/24/2009CN100503571C Tetrahydro isoquinoline derivative and its preparation process and medicine use
06/18/2009WO2009044019A3 1-oxo-isoindoline-4-carboxamide and 1-oxo-1,2,3,4-tetrahydroisoquinoline-5-carboxamide derivatives, preparation and therapeutic use thereof
06/18/2009WO2009044018A3 Derivatives of 1-oxo-1,2-dihydroisoquinoline-5-carboxamides and of 4-oxo-3,4-dihydroquinazoline-8-carboxamides, preparation thereof and application thereof in therapeutics
06/18/2009US20090156823 Sulfonamide compound and crystal thereof
06/18/2009US20090155906 Cell differentiation suppressing agent, method of culturing cells using the same, culture solution, and cultured cell line
06/17/2009EP2069315A2 Quinazolinone and isoquinolinone acetamide derivatives
06/17/2009EP2069289A1 ISOSERINE DERIVATIVES FOR USE AS COAGULATION FACTOR IXa INHIBITORS
06/17/2009EP2069288A1 TARTRATE DERIVATIVES FOR USE AS COAGULATION FACTOR IXa INHIBITORS
06/17/2009EP1611088B1 Hydroxamates as therapeutic agents
06/16/2009US7547731 Antiinflammatory agents; antiallergens; respiratory system disorders
06/16/2009US7547716 Sulfonamide derivatives
06/16/2009CA2284802C Substituted isoquinolines as ultra short acting neuromuscular blockers
06/11/2009WO2009073545A2 Tetrahydro-isoquinoline ppat inhibitors as antibacterial agents
06/11/2009WO2009073203A1 Trp-m8 receptor ligands and their use in treatments
06/11/2009WO2009071449A1 Pyridylmethyl-sulfonamide compounds
06/11/2009WO2009071448A1 Pyridylmethyl-sulfonamide compounds
06/11/2009WO2009008920A3 Hydroxamic acid derivatives of 4-phenyl 4-hydroxy, 4-phenyl 4-alkoxy and 4-phenyl 4-arylalkoxy butyric acid useful as therapeutic agents for treating anthrax poisoning
06/11/2009WO2008135524A3 Substituted anthranilamides and analogues, manufacturing and use thereof as medicaments
06/11/2009US20090149444 Benzylamine analogues
06/11/2009CA2707445A1 Tetrahydro-isoquinoline ppat inhibitors as antibacterial agents
06/11/2009CA2705489A1 Pyridylmethyl-sulfonamide compounds
06/10/2009EP2066640A2 2-(1-oxo-1h-isoquinolin-2-yl) acetamide derivatives
06/10/2009CN101454289A Substituted tetrahydroisoquinoline compounds, their preparation and use in medicaments
06/10/2009CN101450934A Sulfonyl-derivatives as novel inhibitors of histone deacetylase
06/10/2009CN100497358C Iridium compound and organic electroluminescent device using the same
06/10/2009CN100497314C Substituted 4-phenyltetrahydroisoquinolinium, process for their preparation, their use as a medicament, and medicament containing them
06/10/2009CN100497313C New isoquinoline compounds, their preparation method and medicine composition containing them
06/09/2009US7544699 Aryl and heteroaryl compounds, compositions, and methods of use
06/09/2009CA2583764C Thrombopoietin activity modulating compounds and methods
06/04/2009US20090143402 Isoquinolinone derivatives as nk3 antagonists
06/04/2009US20090143372 Chemical compounds
06/04/2009US20090143354 P2X7 Receptor Antagonists and Their Use
06/04/2009US20090143272 Organic catalyst with enhanced solubility
06/03/2009CN101445501A Fused compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor
06/03/2009CN100494180C Preparation method and uses of isoquinolinium compound and its salt
06/02/2009US7541467 N,N,N',N'-tetrakis(2-quinolylmethyl)ethylenediamine; reacting with Zinc ions; inhibition of photoinduced electron transfer (PET)
06/02/2009US7541369 Amino-derivatives as novel inhibitors of histone deacetylase
06/02/2009US7541357 Aryl- and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
06/02/2009US7541332 reporter system reflecting the transport process that transports GPI-anchored proteins to the cell wall was constructed and compounds inhibiting this process were discovered; antifungal agents; inhibiting expression of cell wall glycoproteins and preventing pathogens from showing pathogenicity
05/2009
05/28/2009US20090137594 Pentafluorosulphanyl-Substituted Compound And Its Use For Producing Medicaments
05/27/2009EP2061764A1 Heterocyclic derivatives binding to the peripheral-type benzodiazepine receptor (pbr)
05/27/2009EP2061763A2 Process for the preparation of substituted-1,2,3,4-tetrahydroisoquinoline derivates
05/27/2009EP2061465A2 Derivatives of 4-(n-azacycloalkyl) anilides as potassium channel modulators
05/27/2009EP1730141B1 Compounds for the treatment of diseases
05/27/2009CN101443315A Bicycloheteroaryl compounds as P2X7 modulators and uses thereof
05/27/2009CN101440097A 1-(3',4',5'- trisubstituted phenyl)- isoquinoline compound and medical use thereof
05/27/2009CN101440096A 1-(3',4',5'- trisubstituted phenyl)- tetrahydroisoquinoline compound and its use
05/26/2009US7538241 Such as methyl 3,5-dihydroxy-2-phenylphenylacetate; antitumor activity; leukemia, multiple myeloma, lymphoma; heat shock protein 90 (Hsp90) suppression
05/26/2009US7538121 Vanilloid receptor modulators
05/26/2009CA2533685C Nitrogen-containing fused heterocyclic carboxylic acid compounds
05/26/2009CA2344058C Diaminopropionic acid derivatives
05/22/2009WO2009064959A1 Isoquinoline modulators of atp-binding cassette transporters
05/22/2009CA2705562A1 Isoquinoline modulators of atp-binding cassette transporters
05/21/2009US20090131505 chronic lymphocytic leukemia or acute lymphoblastic leukemia; use of specific compound (1R)-cyclopropanecarboxylic acid {2-[2-carbamoyl-1-(3-ethoxy-4-methoxy-phenyl)-ethyl]-7-chloro-3-oxo-2,3-dihydro-1H-isoindol-4-yl}-amide
05/21/2009US20090131473 2-(aryloxy) acetamide factor viia inhibitors useful as anticoagulants
05/21/2009US20090131456 Caspase inhibitors and uses thereof
05/21/2009US20090131411 monoamidino-containing compounds having good bioavailability and/or solubility, used as potent and specific inhibitors of blood coagulation in mammals, and as therapeutic agents for disease states characterized by coagulation disorders
05/21/2009US20090126125 Styryl tetrahydroquinolinium thiol/disulfide dye compound and method for lightening keratin materials using the same
05/20/2009CN100488508C Pharmaceutical composition containing tetrahydroisoquinoline compounds
05/19/2009CA2209167C Hydroxylamine derivatives useful for enhancing the molecular chaperon production and the preparation thereof
05/14/2009WO2009060835A1 Novel ubiquilin-binding small molecule
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