| Patents for C07D 217 - Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems (11,865) |
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| 06/26/2008 | US20080153868 Substituted Tetrahydroisoquinolines as Beta-secretase Inhibitors |
| 06/26/2008 | US20080153843 Bradykinin 1 receptor (B1R) antagonists for treating various inflammatory diseases, pain, obesity; compounds bind to both rat and human receptors for pharmacological testing; ether and amide-functional N-heterocycle sulfonamides |
| 06/26/2008 | US20080153812 Novel compounds |
| 06/26/2008 | US20080153799 Novel Quinoline-Carbaxamides as Jak3 Kinase Modulators |
| 06/26/2008 | CA2695613A1 Sulfonamide derivatives with therapeutic indications |
| 06/25/2008 | EP1933622A2 Bicycloheteroaryl compounds as p2x7 modulators and uses thereof |
| 06/25/2008 | CN101208305A 3,4-dihydroisoquinolinium salt derivatives |
| 06/25/2008 | CN100396679C Piperazinyl-, piperidinyl- and morpholinyl-derivatives as novel inhibitors of histone deacetylase |
| 06/24/2008 | US7390902 N-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-ethyl]-2-methoxy-5-iodo-benzamide; high affinity and high selectivity for sigma 2 receptors; Bromine, Iodine, Carbon, Tritium radioisitops; PET and SPECT; breast cancer |
| 06/24/2008 | US7390833 osteoarthritis; compounds inhibit Aggrecanase Activity of a disintegrin and metalloprotease with thrombosondin type I motifs; biaryl sulfonamid derivatives; N-({4'-[2-4-methylisoquinolin-3-yl)ethyl]-1,1 '-biphenyl-4-yl}sulfonyl)-D-valine |
| 06/24/2008 | US7390820 Substituted quinolinone derivatives and methods of use |
| 06/19/2008 | WO2008073390A2 Preparation of 3,4-dihydroisoquinolines from an acid and an amine |
| 06/19/2008 | WO2008073389A2 Preparation of hexahydroisoquinolines from dihydroisoquinolines |
| 06/19/2008 | US20080146642 Propanesulfonic acid amino acid prodrugs that can deliver 3-amino-1-propanesulfonic acid (3APS) by minimizing metabolism associated with that drug, particularly compounds that block or protect amino group of 3APS such that it avoids metabolism by transaminases or monoamine oxidase; Alzheimer's disease |
| 06/19/2008 | US20080146597 Therapeutic Tetrahydroisoquinoline-Based Compositions for Cancer Therapy |
| 06/19/2008 | US20080146566 treatment of diseases mediated by cytokines; N-cyclopropyl-4-methyl-3-(1-oxoisoquinolin-2(1H)-yl)benzamide; rheumatoid arthritis, asthma, chronic obstructive pulmonary disease, inflammatory bowel disease, multiple sclerosis, AIDS, septic shock, congestive heart failure, ischaemic heart disease, psoriasis |
| 06/19/2008 | US20080146546 Bicyclic and Tricyclic Heteroaromatic Compounds |
| 06/19/2008 | CA2672745A1 A process for the preparation of hexahydroisoquinolines from 1,2,3,4-tetrahydroisoquinolines |
| 06/19/2008 | CA2672744A1 Improved preparation of 3,4-dihydroisoquinolines in the synthesis of morphinans |
| 06/19/2008 | CA2670843A1 Preparation of tetrahydroisoquinolines from dihydroisoquinolines |
| 06/19/2008 | CA2670834A1 Preparation of 3,4-dihydroisoquinolines from an acid and an amine |
| 06/18/2008 | EP1931636A1 Isoquinolines as igf-1r inhibitors |
| 06/18/2008 | CN100395237C 2,5-substituted tetrahydroisoquinolines for use as 5-HT6 modulators |
| 06/17/2008 | US7388019 3-amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes |
| 06/17/2008 | CA2163361C Therapeutic substituted guanidines |
| 06/12/2008 | WO2008070121A1 Intermediate duration neuromuscular blocking agents and antagonists thereof |
| 06/12/2008 | WO2007148208A3 Carbonylated (aza) cyclohexanes as dopamine d3 receptor ligands |
| 06/12/2008 | US20080139610 Derivatives of 4-(n-azacycloalkyl) anilides as potassium channel modulators |
| 06/12/2008 | US20080139605 Substituted prolinamides, manufacturing, and the use thereof as medicaments |
| 06/12/2008 | US20080139565 Anthranilic Acid Derivatives and Their Use in Treatment of Diseases of Lipid Metabolism, in Particular Dyslipidaemia |
| 06/11/2008 | EP1928836A1 Substituted 4-phenyltetrahydroisoquinolines, method of producing them, their use as medicament, and also medicament containing them |
| 06/11/2008 | EP1601656A4 Tetrahydroquinoline derivatives useful as serine protease inhibitors |
| 06/11/2008 | EP1485348B1 Carbonylamino-derivatives as novel inhibitors of histone deacetylase |
| 06/11/2008 | EP1368032B1 Excitatory amino acid receptor antagonists |
| 06/11/2008 | CN101198685A Process of producing bleach boosters |
| 06/11/2008 | CN101198591A Process of producing bleach boosters |
| 06/11/2008 | CN100393703C 1,2,3,4-tetrahydroisoquinoline derivatives |
| 06/10/2008 | US7384929 N-aryl azaspiroalkene and azaspiroalkane compounds and methods of preparation and use thereof |
| 06/10/2008 | CA2371827C Amide compounds for the potentiation of cholinergic activity |
| 06/05/2008 | WO2008012782A3 Labelled analogues of halobenzamides as radiopharmaceuticals |
| 06/05/2008 | US20080132521 Isoquinolinone Derivatives and Their Use As Therapeutic Agents |
| 06/05/2008 | US20080132499 Platelet adp receptor inhibitors |
| 06/04/2008 | EP0931071B1 Methods of making hiv-protease inhibitors and intermediates for making them |
| 06/04/2008 | CN101193863A 5(Z)-5-(6-quinoxalinylmethylidene)-2-[(2,6-dichlorophenyl)amino]-1,3-thiazol-4(5H)-one |
| 06/03/2008 | US7381719 To treat obesity and Related Diseases; oral bioavailablility, oral administration; inhibition of orexigenic effects; side effects reduction; weight loss while maintaining or minimizing the loss of lean muscle mass; 6-[4-(2-Benzylamino-ethyl)-phenoxy]-nicotinamide |
| 05/29/2008 | WO2008062472A2 Process for the preparation of memantine |
| 05/29/2008 | WO2008019356A3 Process for the preparation of substituted-1,2,3,4-tetrahydroisoquinoline derivates |
| 05/29/2008 | US20080124571 Obtaining long-life blue light emission with high luminous efficiency |
| 05/29/2008 | CA2706070A1 Therapeutic tetrahydroisoquinoline-based compositions for cancer therapy |
| 05/29/2008 | CA2669083A1 5, 6, or 7-substituted-3-(hetero)arylisoquinolinamine derivatives as antitumor agents |
| 05/28/2008 | EP1924551A2 Organic compounds |
| 05/27/2008 | US7378428 phosphodiesterase inhibitors; (Z)-2-(7-bromomethyl-3,3-dimethyl-3,4-dihydro-(2H)-isoquinolin-1-ylidene)-1-(adamantan-1-yl)ethan-1-one; graft versus host disease, osteoporosis, bone fracture, restenosis, arteriosclerosis, obesity, ischemic reperfusion injury, depression, allergies, transplant rejection |
| 05/22/2008 | US20080119512 Carboxamide Derivatives as Therapeutic Agents |
| 05/21/2008 | EP1922308A2 Processes for optical resolution of 1-phenyl-1,2,3,4-tetrahydroisoquinoline |
| 05/21/2008 | EP1562595B1 Diaryl ethers as opioid receptor antagonists |
| 05/21/2008 | EP1284734B1 Isoquinoline derivatives as protein kinase inhibitors |
| 05/21/2008 | CN101184488A Substituted 4-phenyltetrahydroisoquinolines, methods for producing them, their use as drug, and drug containing them |
| 05/20/2008 | US7375204 reporter system reflecting the transport process that transports GPI-anchored proteins to the cell wall was constructed and compounds inhibiting this process were discovered; antifungal agents; inhibiting expression of cell wall glycoproteins and preventing pathogens from showing pathogenicity; DNA |
| 05/20/2008 | US7375126 Such as N-(5-tert-butyl-23-dihydro-1H-inden-1-yl)-N' -5-isoquinolinylurea therapy for pain, antiinflammatory agents, incintinence, bladder overactivity |
| 05/20/2008 | US7375099 Malonamide derivatives |
| 05/15/2008 | US20080114029 Crystalline form of 1(S)-phenyl-1,2,3,4-tetrahydroisoquinoline; urinary antispasmodic |
| 05/15/2008 | US20080113975 Thiourea compounds |
| 05/14/2008 | CN101177385A Aryl sulfonic acid amides and analogues as well as its purpose in curing neural degeneration disease |
| 05/14/2008 | CN101177370A Method for synthesizing heteroaromatic carboxylate and heterocyclic amino acid |
| 05/13/2008 | US7371764 agricultural and horticultural fungal infections of plants; novel N-alkynyl-2-quinolin-(isoquinolin- and quinazolin-)oxyalkylamides; 2-(6-quinolinyloxy)-N-(4-methylpent-2-yn-4-yl) butyramide |
| 05/13/2008 | US7371762 Infections caused by Gram positive and/or negative pathogens |
| 05/08/2008 | US20080108820 First isolated from the sponge Hemiasterella; for treatment of cancer; prevention of restenosis of blood vessels subject to traumas such as angioplasty and stenting; methods for synthetic preparation |
| 05/08/2008 | US20080108649 Bicyclic modulators of androgen receptor function |
| 05/08/2008 | US20080107599 Radiolabelled benzamide analogues, their synthesis and use in diagnostic imaging |
| 05/07/2008 | EP1918272A1 Pharmaceutically active compounds and methods of use |
| 05/07/2008 | EP1917246A1 Benzoquinazoline derivatives and their use in treating bone disorders |
| 05/07/2008 | EP1917244A2 Hetaryl-substituted guanidine compounds and use thereof as binding partners for 5-ht5-receptors |
| 05/07/2008 | CN101175726A Process for the preparation of opioid modulators |
| 05/07/2008 | CN101175725A Process for the preparation of opioid modulators |
| 05/07/2008 | CN100386319C Tetra hydro iso quinoline compounds possessing anti breed and anti fungus activity and its salt |
| 05/06/2008 | US7368453 Quinazolinone compounds with reduced bioaccumulation |
| 05/02/2008 | WO2008049919A2 Rho kinase inhibitors |
| 05/02/2008 | WO2007109160A3 Bicycloheteroaryl compounds as p2x7 modulators and uses thereof |
| 05/01/2008 | US20080103311 Retroviral protease inhibitors |
| 05/01/2008 | US20080103172 as tyrosine, serine/threonine, cyclin-dependent kinases, HER protein; 5-{2-[3-[4-trifluoromethyl-1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazol-2-yl]-1-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrazol-4-yl]-vinyl}-pyridine-3-carbaldehyde; antiproliferative, antiinflammatory agent, neurodegenerative diseases |
| 04/29/2008 | US7365070 Such as N-{2-[2-(5-Bromo-2-methoxy-phenyl)-ethyl]-3-fluoro-benzoyl}-N'-butyl-guanidine; involuntary weight loss disorders |
| 04/29/2008 | US7365065 Antigonadotrophins; Breast and prostate cancer, endometriosis and benign prostate hyperplasia; regulation of fertility; in-vitro fertilisation; oral administration; inexpensive; 3-Amino-4-chloro-N-[4-chloro-5-(2,3-dihydro-benzo[1,4]oxazine-4-carbonyl)-thiophen-3-ylmethyl]-N-methyl-benzenesulfonamide |
| 04/24/2008 | WO2008048503A2 Imidazole substitured pyrazole kinase inhibitors |
| 04/24/2008 | WO2007149730A3 Inhibitors of akt (protein kinase b) |
| 04/24/2008 | US20080097102 Aminotetralin-derived urea modulators of vanilloid vr1 receptor |
| 04/24/2008 | US20080097100 Opiate Intermediates and Methods of Synthesis |
| 04/24/2008 | US20080096916 Drugs And Prodrugs Useful The Treatment Of Energy Balance In Ruminants |
| 04/24/2008 | US20080096883 Trifluoromethyl substituted benzamides as kinase inhibitors |
| 04/24/2008 | US20080096875 Hepatitis C virus infection; thiourea-substituted dibenzofuran, fluorene, or carbazole compounds |
| 04/24/2008 | US20080096869 Adamantyl acetamides as 11-beta hydroxysteroid dehydrogenase inhibitors |
| 04/23/2008 | EP1912949A1 Cyclohexylamin isoquinolone derivatives as rho-kinase inhibitors |
| 04/23/2008 | EP1303483B1 Novel thiourea derivatives and the pharmaceutical compositions containing the same |
| 04/22/2008 | US7361663 N-acylpyrrolidin-2-ylalkylbenzamidine derivatives as inhibitors of factor Xa |
| 04/17/2008 | WO2008045671A1 Matrix metalloprotease inhibitors |
| 04/17/2008 | US20080091023 Processes for optical resolution of 1-phenyl-1,2,3,4-tetrahydroisoquinoline |
| 04/17/2008 | US20080090862 Isoquinoline Derivatives as Calpain Inhibitors |
| 04/17/2008 | US20080090860 Side effect reduction; 2-carboxy-4-(2-propoxy-3,5-di-tert-butylphenyl)-benzo[b]thiophene for example; syndrome X, non-insulin dependent diabetes mellitus, cancer, photoaging, acne, psoriasis, obesity, cardiovascular disease, atherosclerosis, uterine leiomyomata, inflamatory or neurodegenerative disease |
| 04/16/2008 | EP1910317A1 1-amino linked compounds |
| 04/16/2008 | EP1910298A2 Phenylglycinamide and pyridylglycinamide derivatives useful as anticoagulants |
| 04/16/2008 | EP1910297A1 Isoquinoline compounds |