Patents
Patents for C07D 217 - Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems (11,865)
12/2008
12/30/2008US7470722 For treating disease, such as cancer, neurological disorders, including polyglutamine-repeat disorders, anemias, thalassemias, inflammatory conditions, autoimmune diseases and cardiovascular conditions
12/25/2008US20080318923 1,3-Dihydro-2H-Indole-2-One Compound and Pyrrolidine-2-One Compound Fused With Aromatic Heterocycle
12/24/2008WO2008156573A1 Kinase inhibitors, compositions thereof, and methods of use therewith
12/24/2008WO2008156142A1 Novel malonic acid sulfonamide derivative and pharmaceutical use thereof
12/24/2008WO2008155752A1 (1r,1'r)-atracurium salts separation process
12/24/2008WO2008086269A3 6-aminoisoquinoline compounds useful as kinase modulators
12/24/2008EP2004595A1 N-phenyl-1,1,1-trifluoromethanesulfonamide hydrazone derivative compounds and their usage in controlling parasites
12/24/2008EP1620102B1 3-(1-naphthyl)-2-cyanopropanoic acid derivatives as estrogen receptor ligands
12/24/2008CN100445280C Glutamine fructose-6-phosphate amidotransferase (GFAT) inhibitors
12/24/2008CA2690410A1 Kinase inhibitors, compositions thereof, and methods of use therewith
12/24/2008CA2687157A1 (1r,1'r)-atracurium salts separation process
12/23/2008US7468393 Diarylsulfones as 5-HT2A antagonists
12/23/2008US7468348 Using polymeric structure of sugar based polyols and other polyols as starting materials for attachment of organic bleach catalysts; benefits in detergents such as soil suspension, bleaching action and increased surfactant availability in the presence of free hardness
12/23/2008US7468347 Using polymeric structure of sugar based polyols and other polyols as starting materials for attachment of organic bleach catalysts; benefits in detergents such as soil suspension, bleaching action and increased surfactant availability in the presence of free hardness
12/18/2008WO2008154484A1 Ire-1a inhibitors
12/18/2008WO2008154243A1 Method for making tetrabenazine compounds
12/18/2008WO2008130319A3 Novel n-tetrahydronaphtalene or n-chromane carboxamide derivatives for the treatment of pain
12/18/2008WO2008033764A3 Quinazolinone and isoquinolinone acetamide derivatives
12/18/2008US20080312445 Novel Crystalline Forms Of Nelfinavir Mesylate
12/18/2008US20080312292 Antipruritics
12/18/2008US20080312262 Such as 2-(methylamino)-2-oxoethyl {2-[(4-chlorophenyl)oxy]ethyl}carbamate; sleep disorders
12/18/2008US20080312237 Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same
12/18/2008US20080311113 Method for treating adamts-5-associated disease
12/18/2008CA2690913A1 Ire-1alpha inhibitors
12/17/2008EP2001474A2 Bicycloheteroaryl compounds as p2x7 modulators and uses thereof
12/17/2008EP1773763B1 Lysine based compounds
12/11/2008WO2008149181A1 Pro-drugs of nsaias with very high skin and membranes penetration rates and their new medicinal uses
12/11/2008WO2008148468A1 Di(hetero)arylcyclohexane derivatives, their preparation, their use and pharmaceutical compositions comprising them
12/11/2008WO2008109181A3 Metalloprotease inhibitors containing a heterocyclic moiety
12/11/2008WO2008034039A3 Novel tetrahydro-isoquinolines
12/11/2008WO2008033757A3 2-(1-oxo-1h-isoquinolin-2-yl) acetamide derivatives
12/11/2008WO2008008374A3 Ccr2 inhibitors and methods of use thereof
12/11/2008US20080306269 Intermediates useful for making tetrabenazine compounds
12/11/2008US20080306258 Cyclopropane compounds and pharmaceutical use thereof
12/11/2008US20080306086 for the treatment of depression, pain, psychosis, Parkinson's disease, schizophrenia, anxiety and attention deficit hyperactivity disorder (ADHD); 2-{4-[(2S,4S)-1-benzyl-4-(2,4-difluoro-benzylamino)-pyrrolidine-2-carbonyl]-piperazin-1-yl}-benzonitrile
12/11/2008US20080306085 Non-imidazole aryloxyalkylamines
12/11/2008CA2691446A1 Pro-drugs of nsaias with very high skin and membranes penetration rates and their new medicinal uses
12/11/2008CA2689985A1 Di(hetero)arylcyclohexane derivatives, their preparation, their use and pharmaceutical compositions comprising them
12/10/2008EP1999113A1 Substituted 1-amino-4-phenyl-dihydroisoquinolines, method for the production thereof, use thereof as a medicament, and medicaments containing them
12/10/2008EP1998775A2 Bis1,2,3,4-tetrahydroisoquinoline derivatives and their uses as pharmaceuticals
12/09/2008US7462629 Therapy or prevention diseases caused by lymphocyte interaction; antiinflammatory agents; autoimmune disease
12/09/2008US7462628 Preventives/remedies for urinary disturbance
12/09/2008CA2379061C Antibacterial agents
12/04/2008WO2008146774A1 Tetrahydroisoquinolin-1-one derivative or salt thereof
12/04/2008US20080300271 Novel compounds and a novel process for their preparation
12/04/2008US20080300251 Derivatives of 3-Azabicyclo[3.1.0] Hexane as Dipeptidyl Peptidase-IV Inhibitors
12/04/2008CA2688326A1 Tetrahydroisoquinolin-1-one derivative or salt thereof
12/03/2008EP1996585A2 Bicycloheteroaryl compounds as p2x7 modulators and uses thereof
12/03/2008EP1996541A1 2-(aryloxy)acetamide factor viia inhibitors useful as anticoagulants
12/03/2008EP1480954B1 Vanilloid receptor modulators
12/03/2008CN100439332C Novel thiourea derivatives and the pharmaceutical compositions containing thd same
11/2008
11/27/2008WO2008143706A2 Daa peripheral benzodiazepine receptor ligand for cancer imaging and treatment
11/27/2008WO2008143263A1 1-substituted tetrahydroisoquinoline compound
11/27/2008WO2008121850A3 Small-molecule modulators of melanin expression
11/27/2008WO2007136790A3 Intracellular kinase inhibitors
11/27/2008US20080293763 Novel nitrogen-containing heteroaryl compounds and methods of use thereof
11/27/2008US20080293709 Novel 2-Amino-Heterocycles Useful in the Treatment of Abeta-Related Pathologies
11/27/2008US20080293684 Heterocyclic Acetophenone Potentiators of Metabotropic Glutamate Receptors
11/27/2008US20080293678 Organic Nitric Oxide Donor Salts of Angiotensin Converting Enzyme Inhibitors, Compositions and Methods of Use
11/27/2008CA2687958A1 1-substituted tetrahydroisoquinoline compound
11/26/2008EP1994006A1 Polymerisation of ethylene and alpha-olefins with imino-quinolinol complexes
11/26/2008EP1994005A1 Tetrahydronaphthaline derivatives, methods for the production and use thereof as anti-inflammatory agents
11/26/2008EP1993560A2 Cannabinoid receptor antagonists/inverse agonists useful for treating obesity
11/26/2008EP1414455B1 Isoquinoline inhibitors of p38
11/26/2008CN100436462C Reaction method of biological alkali, reaction product and use thereof
11/26/2008CN100436420C 4-phenyl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine and serotonin
11/25/2008US7456196 Alzheimer's disease; antihistamine; attention deficit disorder; hyperactivity; bipolar disorder; cognition activators; psychological disorder; anticancer agent; antidepressants; antiepileptic agents; gastrointestinal disorder; analgesics; 6-{2-[(2R)-2-methyl-1-pyrrolidinyl]ethyl}-2-(3-pyridinyl)quinoline
11/25/2008US7456195 Phenylglycinamide and pyridylglycinamide derivatives useful as anticoagulants
11/25/2008US7456183 Melanocortin-4 receptor agonists; obesity, type II diabetes; such as N-(2-(2-(2,4-dichlorophenyl)ethyl)-1-oxo-2,3-dihydro-1H-isoindol-5-yl) -3-methyl-N'-(2,6,6-trimethylbicyclo(3.1.1)hept-3yl)piperazine-1-carboximidamide
11/20/2008WO2008141227A1 Novel peptide inhibitors of hepatitis c virus replication
11/20/2008US20080287676 Fused compounds that inhibit vanilloid receptor subtype 1 (vr1) receptor
11/20/2008US20080287490 Bis-pyridino containing compounds for the use in the treatment of CNS pathologies
11/20/2008US20080287489 Ophthalmic compositions for treating ocular hypertension
11/20/2008US20080287415 Bicycloheteroaryl compounds as P2X7 modulators and uses thereof
11/20/2008CA2686546A1 Novel peptide inhibitors of hepatitis c virus replication
11/18/2008US7452994 Selective hydrogenation of amino-substituted fused bicyclic aromatic ring system, preparation of racemic amino substituted fused bicyclic ring system via nitrosation, enzymatic resolution of racemic mixture to produce (R)- and (S)-forms
11/18/2008US7452905 Phenylalanine derivatives
11/18/2008US7452899 Alzheimer's disease; bridged bicycloalkyl sulphonamide and sulphamide derivatives; [9-endo]2',3', 4',5'-Tetrahydro-5'-(2.2.2-trifluoroethyl)spiro[3-{(E)-2-[5-(4-fluorophenyl)-1-methyl-1H-pyrazol-3-yl]ethenyl}-4-methyl bicyclo[4.2.1]non-3-ene]-9,3'-[1,2,5]thiadiazol-1',1'-dioxide
11/18/2008CA2266526C Hetaroyl cyclohexanedione derivatives with herbicidal effect
11/18/2008CA2221517C Synthesis of n-substituted oligomers
11/13/2008WO2008136378A1 Novel sulfonamide derivative and salt thereof
11/13/2008WO2008135524A2 Substituted anthranilamides and analogues, manufacturing and use thereof as medicaments
11/12/2008EP1624868B1 "(2-hydroxy-2-(4-hydroxy-3-hydoxymethylphenyl)-ethylamino)- propyl]phenyl derivatives as beta2 agonists
11/12/2008CN100432056C Tetrahydroisoquinolyl acetamide derivatives for use as orexin receptor antagonists
11/11/2008US7449477 7-phenyl-isoquinoline-5-sulfonylamino derivatives as inhibitors of akt (protein kinase B)
11/06/2008WO2008133155A1 Bicyclic heterocyclic compound
11/06/2008WO2008132748A1 Process for producing cisatracurium compounds and associated intermediates
11/06/2008WO2008132746A1 Novel isoquinolinium compounds useful in the preparation of cisatracurium and associated intermediates
11/06/2008WO2008132679A1 Bridged six-membered ring compounds
11/06/2008WO2008131779A1 Isoquinolinone derivatives as nk3 antagonists
11/06/2008WO2008107887A3 (1r,1'r)-atracurium salts separation process
11/06/2008WO2008011462A3 Process for preparing solifenacin and its salts
11/06/2008WO2007106721A3 Cannabinoid receptor antagonists/inverse agonists useful for treating obesity
11/06/2008US20080274879 Process of producing an organic catalyst
11/06/2008CA2685491A1 Process for producing cisatracurium compounds and associated intermediates
11/06/2008CA2685488A1 Novel isoquinolinium compounds useful in the preparation of cisatracurium and associated intermediates
11/06/2008CA2683866A1 Bridged six-membered ring compounds
11/06/2008CA2683159A1 Isoquinolinone derivatives as nk3 antagonists
11/05/2008EP1987006A1 Novel aminoalcohol-substituted aryldihydroisoquinolinones, process for their preparation and their use as medicaments
11/05/2008EP1053227B1 Ppar-gamma modulators
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