Patents for C07D 217 - Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems (11,865) |
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09/02/2008 | US7420089 for hepatitis C; histone deacetylase inhibitors; N-hydroxy-4-{[(naphthyl-carbonylamino]alkoxy}benzamides; anticarcinogenic agent; acute promyelocytic leukemia; cell-cycle arrest in late G1 phase or at the G2/M transition |
09/02/2008 | US7420003 Compounds and a novel process for their preparation |
09/02/2008 | CA2411412C Indole derivatives useful for the treatment of cns disorders |
09/02/2008 | CA2273023C Aminoguanidines and alkoxyguanidines as protease inhibitors |
08/28/2008 | WO2008103615A1 Isoquinolines useful as inducible nitric oxide synthase inhibitors |
08/28/2008 | US20080207689 Formamide Derivatives For The Treatment of Diseases |
08/28/2008 | US20080207685 Heterocyclic Compounds As Modulators Of Peroxisome Proliferator Activated Receptors, Useful For The Treatment And/Or Prevention Of Disorders Modulated By A Ppar |
08/28/2008 | US20080207607 Antiarthritic agents; antiinflammatory agents; arteriosclerosis; multiple sclerosis |
08/27/2008 | EP1960363A2 Quinolone based compounds exhibiting prolyl hydroxylase inhibitory activity, and compositions, and uses thereof |
08/27/2008 | CN101253147A Organic compounds |
08/27/2008 | CN101250157A Method for synthesizing 2-substituted-3,4-dihydro-1-isoquinoline ketones and use thereof for preparing cardiovascular agents |
08/21/2008 | WO2008019055A3 Processes for optical resolution of 1-phenyl-1,2,3,4-tetrahydroisoquinoline |
08/21/2008 | US20080200682 Process of Producing Bleach Boosters |
08/21/2008 | US20080200465 Antipathogenic benzamide compounds |
08/20/2008 | EP1957462A2 Novel 2-amino-heterocycles udeful in the treatment of abeta-related pathologies |
08/20/2008 | EP1957449A1 Compounds for the treatment of inflammatory disorders and microbial diseases |
08/20/2008 | EP1957058A1 Compounds for the treatment of inflammatory disorders and microbial diseases |
08/20/2008 | EP1249233B1 Npyy5 antagonists |
08/20/2008 | CN101248069A Androgen receptor modulators and method of treating disease using the same |
08/20/2008 | CN100412062C Synthesis of enantiomerically pure amino-substituted fused bicyclic rings |
08/19/2008 | US7414063 e.g. 2-(2-bromo-4-fluoro-phenoxy)-ethyl]-[2-(isoquinoline-5-sulfonylamino)-ethyl]-carbamic acid tert-butyl ester; serine/threonine kinase inhibitor; anticarcinogenic agent; solid tumor, leukemia |
08/14/2008 | WO2008097428A2 Compounds and compositions as modulators of gpr119 activity |
08/14/2008 | WO2008096739A1 Benzimidazole compound-containing composition and light-emitting device using the composition |
08/14/2008 | WO2008095852A1 Bronchorelaxing arylamides |
08/14/2008 | US20080194621 Substituted 4-phenyltetrahydroisoquinolines, process for their preparation, pharmaceutical compositions and therapeutic use |
08/14/2008 | US20080194557 methods of treating, managing and preventing pain, inflammation, cancer, and ocular diseases and disorders, and to compounds and pharmaceutical compositions useful in such methods |
08/14/2008 | CA2677263A1 Compounds and compositions as modulators of gpr119 activity |
08/13/2008 | EP1955697A1 2-aminobenzamide derivative |
08/13/2008 | EP1954132A2 Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same |
08/13/2008 | EP1664023B1 Sustituted isoquinoline derivatives and methods of use |
08/13/2008 | EP1501803B1 Tetrahydropyranyl cyclopentyl tetrahydroisoquinoline modulators of chemokine receptor activity |
08/13/2008 | EP1322309B1 High affinity small molecule c5a receptor modulators |
08/13/2008 | EP1020445B1 Fused pyridine derivatives |
08/12/2008 | US7410982 Heteroaryloxy/thio propanamines; improved acid stability, potency and selectivity to the dopamine transporter; improved ADME properties e.g. reduced tendency to act as a substrate and/or inhibitor the enzyme Cytochrome P450; pain; [(3R)-3-(Isoquinolin-4-yloxy)-3-phenyl-propyl]-methyl-amine hydrochloride |
08/07/2008 | WO2008092292A1 Isoquinolone compounds as subtype-selective agonists for melatonin receptors mt1 and mt2 |
08/07/2008 | WO2008092231A1 Compounds for the prevention and treatment of cardiovascular diseases |
08/07/2008 | CA2676984A1 Compounds for the prevention and treatment of cardiovascular diseases |
08/06/2008 | EP1951674A1 Sulfonamide derivatives and use thereof for the modulation of metalloproteinases |
08/06/2008 | EP1439169B1 Difluoroalkene derivative, pest control agent containing the same, and intermediate therefor |
08/05/2008 | US7408065 P2X7 receptor antagonists and their use |
08/05/2008 | US7407972 e.g. 4,5-Dihydro-pyrazole-1,5-dicarboxylic acid 1-[(4-chloro-phenyl)-amide] 5-[(3-fluoro-2'-methanesulfonyl-biphenyl-4-yl)-amide]; anticoagulant, thrombolytic agent; thrombus formation within blood vessels; cardiovascular disease |
08/05/2008 | CA2331593C Metabolites of ecteinascidin 743 |
07/31/2008 | WO2008090434A1 Substituted n-bicyclicalkyl bicyclic carboxyamide compounds |
07/31/2008 | WO2007121453A3 2-hydroxy-1-oxo 1,2 dihydro isoquinoline chelating agents |
07/31/2008 | US20080182871 e.g. 3-(3-methoxyphenyl)isoquinolin-1-amine; antiproliferative and antigrowth agent; breast tumors, prostate tumors, colon tumors, ovary tumors, kidney tumors, pancreas tumors, glioblastoma and melanoma. |
07/31/2008 | US20080182839 LFA1 related immune and/or inflammatory disorders; interactions with leukointegrins; such as fused nitrogen heterocyclic secondary amine derivatives |
07/30/2008 | EP1592684B1 Malonamide derivatives as gamma-secretase inhibitors |
07/30/2008 | CN101233112A Benzoquinazoline derivatives and their use in treating bone disorders |
07/30/2008 | CN101230039A Compound having anti-fouling activity as well as extraction method and use thereof |
07/30/2008 | CN101230036A Method for preparing heterocyclic aryl-aryl biphenyl compounds |
07/29/2008 | US7405299 Compounds as pharmaceutical agents |
07/29/2008 | US7405230 Phosphodiesterase 4 inhibitors, including N-substituted aniline and diphenylamine analogs |
07/29/2008 | US7405227 Treatment of cancer |
07/29/2008 | CA2333008C New heterocyclically substituted amides, their production and their use |
07/24/2008 | US20080176896 Modulators of cellular adhesion |
07/24/2008 | US20080176849 e.g. N-hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]-amino]methyl]phenyl]-2E-2-propenamide; histone deacetylase inhibitor; anticarcinogenic, antitumor, antiproliferative agents; improved stability |
07/24/2008 | US20080176838 e.g. [3-[(Cyclopropanecarbonyl-amino)-methyl]-pyrrolidin-1-yl}-(2-fluoro-benzyl)-propyl]-carbamic acid tert-butyl ester; dipeptidyl-peptidase inhibitor; antidiabetic, hypoglycemic agent; metabolic disorders, obesity, non-insulin dependent diabetes; |
07/23/2008 | EP1945636A2 Polymorphs of solifenacin intermediate |
07/23/2008 | CN101228132A Cyclohexylamin isoquinolone derivatives as rho-kinase inhibitors |
07/23/2008 | CN100404509C Isoquinoline compound, preparation method and application of salt thereof |
07/22/2008 | US7402675 Process for the synthesis of amine ethers from secondary amino oxides |
07/22/2008 | US7402673 Diamine β2 adrenergic receptor agonists |
07/22/2008 | US7402595 JNK inhibitor |
07/22/2008 | US7402594 isoquinoline ring joined to a phenyl ring by a chemical group that is two bonds long and at least one cation or cationic group selected from sodium, potassium, ammonium, and tetraalkylammonium; Factor Xa inhibitor; anticoagulant; straightforward and economical synthesis |
07/22/2008 | US7402583 Substituted quinolines as antitumor agents |
07/17/2008 | WO2008086047A1 Rho kinase inhibitors |
07/17/2008 | CA2674389A1 Rho kinase inhibitors |
07/15/2008 | US7399866 2-(Imidazol-1-ylalkyl)-3H-quinazolin-4-one derivatives; mitotic kinesin KSP inhibitors; anticarcinogenic, antiinflammatory, and antiproliferative agents |
07/10/2008 | WO2008062472A3 Process for the preparation of memantine |
07/10/2008 | WO2008019057A3 Polymorphs of solifenacin intermediate |
07/10/2008 | US20080167340 6-Aminoisoquinoline Compounds |
07/10/2008 | US20080166765 Fungal cell wall synthesis gene |
07/10/2008 | US20080166593 Organic Electroluminescent Devices |
07/10/2008 | US20080166332 Methods of Treatment of Amyloidosis Using Subsituted Ethanolcyclicamine Aspartyl Protease Inhibitors |
07/09/2008 | EP1940814A1 Piperazine derivatives as antimalarial agents |
07/09/2008 | EP1940796A1 Isoquinolines derivatives as igf-1r inhibitors |
07/09/2008 | CN100400512C Benzoic acid derivatives as modulators of PPAR alpha and gamma |
07/08/2008 | US7396838 antitumor, anticarcinogenic agents; cytotoxic activity and angiogensis inhibitors; leukemia, colorectal cancer; orally |
07/08/2008 | US7396831 Vanilloid receptor ligands and their use in treatments |
07/08/2008 | CA2200324C 4a-aryldecahydroisoquinoline compounds and medicinal use of the same |
07/03/2008 | WO2008078674A1 Glucokinase-activating substance |
07/03/2008 | WO2008077556A1 Cycloalkylamine substituted isoquinoline and isoquinolinone derivatives |
07/03/2008 | WO2008077554A1 Cycloalkylamine substituted isoquinoline derivatives |
07/03/2008 | WO2008077553A1 Cycloalkylamine substituted isoquinolone and isoquinolinone derivatives |
07/03/2008 | WO2008077551A1 Cycloalkylamine substituted isoquinolone derivatives |
07/03/2008 | WO2008049919A3 Rho kinase inhibitors |
07/03/2008 | US20080161347 Substituted Aryl and Heteroaryl Derivatives, Compositions Containing Such Compounds and Methods of Use |
07/03/2008 | US20080161346 Pyridines or pyrimidines having 4-(hydrogenated 1-pyridyl- or hydrogenated 1-isoquinolyl rings, e.g., N-(4-chlorophenyl)-2-(pyridin-4-ylmethyl)-1,2,3,4-tetrahydroisoquinoline-5-carboxamide; kinase inhibitors; inflammation, angiogenesis and cancer |
07/03/2008 | US20080161345 Aryl Sulfonamides |
07/03/2008 | US20080161344 Melanin Concentrating Hormone Receptor Ligands: Substituted Tetrahydroisoquinoline Analogues |
07/03/2008 | US20080161297 Rho kinase inhibitors |
07/03/2008 | CA2673922A1 Cycloalkylamine substituted isoquinoline and isoquinolinone derivatives |
07/03/2008 | CA2673920A1 Cycloalkylamine substituted isoquinoline derivatives |
07/03/2008 | CA2673919A1 Cycloalkylamine substituted isoquinolone and isoquinolinone derivatives |
07/03/2008 | CA2673917A1 Cycloalkylamine substituted isoquinolone derivatives |
07/03/2008 | CA2672088A1 Glucokinase activator |
07/02/2008 | EP1937643A2 Bicycloheteroaryl compounds as p2x7 modulators and uses thereof |
07/02/2008 | CN101213187A Isoquinoline derivatives as inhibitors of RHO-kinase |
06/26/2008 | WO2008076427A2 Naphthalenone compounds exhibiting prolyl hydroxylase inhibitory activity, compositions, and uses thereof |
06/26/2008 | WO2008075353A1 Sulfonamide derivatives with therapeutic indications |