Patents
Patents for C07D 217 - Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems (11,865)
12/2009
12/01/2009US7625929 Oxophenyl-cyclohexyl-propanolamine derivatives, production and use thereof in therapeutics
12/01/2009US7625909 N-{3-[2-(2-Fluoro-4-methoxyphenyl)-ethyl]-4-oxo-3,4-dihydroquinazolin-7yl}-N-indan-2-yl-3,5-dimethylpiperazine-1-carboxamidine; melanocortin-4 receptor agonists; diabetes
11/2009
11/26/2009WO2009142984A1 Alpha-substituted n-sulfonyl gylcine amides antagonists of ccr10, compositions containing the same and methods for using them
11/26/2009WO2009142521A1 Process for preparation of enantiomerically pure (s)-1-phenyi-1,2,3,4- tetrahydroisoquinoline
11/26/2009WO2009141782A1 Tetrahydroisoquinolines as antimalarial agents
11/26/2009US20090291978 Enzyme Inhibitors
11/26/2009US20090291949 Substitute isoquinolines useful in the treatment of diseases such as cancer and atherosclerosis
11/26/2009CA2725140A1 Alpha-substituted n-sulfonyl gylcine amides antagonists of ccr10, compositions containing the same and methods for using them
11/26/2009CA2723612A1 Tetrahydroisoquinolines as antimalarial agents
11/25/2009CN101588803A Intermediate duration neuromuscular blocking agents and antagonists thereof
11/25/2009CN100562513C Benzamide derivative or salt thereof
11/24/2009US7622586 Opiate intermediates and methods of synthesis
11/24/2009CA2385882C Tyrosine derivatives
11/19/2009WO2009139373A1 Amide compound
11/19/2009WO2009112550A4 Novel n-substituted tetrahydroisoquinoline/isoindoline hydroxamic acid compounds
11/19/2009US20090285849 Thiosemicarbazones as anti-virals and immunopotentiators
11/19/2009CA2724077A1 Amide compound
11/19/2009CA2723421A1 Chemical compounds
11/18/2009EP2118074A1 Compounds for the prevention and treatment of cardiovascular diseases
11/18/2009EP2118064A2 6-aminoisoquinoline compounds useful as kinase modulators
11/18/2009EP1306372B1 Heterocycle derivatives and drugs
11/18/2009CN101583601A Isoquinolone compounds as subtype-selective agonists for melatonin receptors MT1 and MT2
11/17/2009US7618978 Amides as BACE inhibitors
11/12/2009WO2009136803A2 Process
11/12/2009US20090281128 Caspase inhibitors and uses thereof
11/12/2009CA2723411A1 Process
11/11/2009EP2116535A1 Glucokinase-activating substance
11/11/2009EP1917246B1 Benzoquinazoline derivatives and their use in treating bone disorders
11/11/2009EP1477186B1 Antipruritics
11/11/2009CN101578266A Cycloalkylamine substituted isoquinoline and isoquinolinone derivatives
11/11/2009CN100558709C Iminium positive ion salts in cleaning compositions
11/11/2009CN100558697C Cycloalkyl inhibitors of potassium channel function
11/10/2009US7615565 VEGFR-2 and VEGFR-3 inhibitory anthranilamide pyridines
11/10/2009US7615553 E.g., N,N-dimethyl,((5-(hydroxyaminocarbonyl)pyrimidin-2-yl)(piperazin-1,4-ylene)sulfonamide; bioavailability; oral administration; metabolic stability; side effect reduction; psoriasis; anticarcinogenic -proliferative, -arthritic, -inflammatory agent; gene therapy; genetic transcription potentiation
11/05/2009WO2009091898A3 6-and 7-amino isoquinoline compounds and methods for making and using the same
11/05/2009US20090275537 Certain chemical entities, compositions, and methods
11/05/2009US20090274656 Hepatitis c virus inhibitors
11/05/2009US20090274652 Hepatitis C Virus Inhibitors
11/04/2009EP2113031A1 Optically active, heteroaromatic beta-hydroxy esters, processes for their preparation from beta-keto esters and processes for the preparation of these beta-keto esters
11/04/2009EP1844045B1 Phenyl methanone derivatives and their use as glycine transporter 1 inhibitors
11/03/2009US7612206 Sigma-2 receptor radiotracers for imaging the proliferative status of solid tumors
11/03/2009US7612091 Caspase inhibitors and uses thereof
11/03/2009US7612090 Use in treatment of a disorder which is created by or is dependent upon decreased availability of serotonin, norepinephrine or dopamine
11/03/2009US7612089 N-[4-(1-methyl-4,5-dihydro-1H-imidazol-2-yl)phenyl]-2N-(4-chlorophenylaminocarbonyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide; thrombosis; inhibits coagulation of a blood sample
10/2009
10/29/2009WO2009131065A1 Long-chain fatty acid elongation enzyme inhibitor comprising arylsulfonyl derivative as active ingredient
10/29/2009WO2009130240A1 Isoquinolinone derivatives as nk3 antagonists
10/29/2009US20090270365 such as N-(2,4-dimethyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)-2-(piperidin-1-ylmethyl)biphenyl-4-carboxamide, having vanilloid receptor 1 antagonistic activity, used as analgesics
10/29/2009US20090270362 Bicyclic mglur5 positive allosteric modulators and methods of making and using same
10/29/2009CA2722075A1 Long-chain fatty acyl elongase inhibitor comprising arylsulfonyl derivative as active ingredient
10/29/2009CA2721260A1 Isoquinolinone derivatives as nk3 antagonists
10/28/2009EP2111399A2 Naphthalenone compounds exhibiting prolyl hydroxylase inhibitory activity, compositions, and uses thereof
10/28/2009EP1633717B1 P2x7 receptor antagonists and their use
10/28/2009CN101565435A P-chiral phospholanes and phosphocyclic compounds and their use in asymmetric catalytic reactions
10/27/2009US7608617 N,N-alkylene-6-(piperidin-1-ylalkoxy)naphthalene-2-carboxamide derivatives, e.g., piperidin-1-yl-[6-(3-piperidin-1-yl-propoxy)-naphthalen-2-yl]-methanone and 3,4-dihydro-1H-isoquinolin-2-yl)-[6-(3-piperidin-1-yl-propoxy)-naphthalen-2-yl]-methanone; especially for treating obesity
10/27/2009CA2318976C Herbicidally active 3-hydroxy-4-aryl-5-oxopyrazoline derivatives
10/22/2009US20090264424 Vanilloid receptor ligands and their use in treatments
10/21/2009EP1280776B1 Substituted benzoic acid amides and use thereof for the inhibition of angiogenesis
10/21/2009CN100551907C Compound in category of aryl methylamino dithio formic ether, preparation method and application
10/20/2009US7605265 Heterodimers and methods of using them
10/20/2009US7605165 Phenylalanine derivatives
10/15/2009CA2720530A1 Sulfonamides
10/14/2009EP1720829B1 Derivatives of heteroaryl-alkylcarbamates, preparation method thereof and use of same as faah enzyme inhibitors
10/14/2009CN101558043A Preparation of hexahydroisoquinolines from dihydroisoquinolines
10/14/2009CN101558035A Preparation of 3,4-dihydroisoquinolines from an acid and an amine
10/14/2009CN100548988C Metabolites of ecteinascidin 743
10/14/2009CN100548299C Excitatory amino acid receptor antagonists
10/13/2009US7601739 Treatment of breast cancer and osteoporosis
10/13/2009US7601738 Excitatory amino acid receptor antagonists
10/13/2009CA2473070C Proline compounds as ns3-serine protease inhibitors for use in treatment of hepatites c virus infection
10/08/2009WO2009121872A2 Tetrahydroisoquinolines, pharmaceutical compositions containing them, and their use in therapy
10/08/2009CA2720004A1 Tetrahydroisoquinolines, pharmaceutical compositions containing them, and their use in therapy
10/07/2009EP2106212A2 Nuclear receptor binding agents
10/07/2009CN101550103A 1, 2, 3, 4-tetrahydroisoquinoline derivatives and synthetic method and uses thereof
10/07/2009CN101550085A Novel organic electroluminescent compounds and organic electroluminescent device using the same
10/06/2009US7598412 Cystic fibrosis transmembrane conductance regulator; ABC transporter mediated diseases like cystic fibrosis; 5-methoxy-N-((1-(3,4-dimethoxyphenyl)-cyclohexyl)methyl)benzofuran-2-carboxamide; or sulfonamide analogs; chloride or bicarbonate channel modulators
10/06/2009US7598242 Compounds for the treatment of inflammatory disorders
10/06/2009CA2402431C 1,2,3,4-tetrahydroisoquinoline derivatives
10/01/2009WO2009119534A1 Novel tetrahydroisoquinoline derivative
10/01/2009WO2009118765A2 Novel monoamine re-uptake inhibitor
10/01/2009WO2009060835A8 Novel ubiquilin-binding small molecule
10/01/2009US20090247757 Ligands, their preparation and uses thereof in asymmetric reactions
10/01/2009US20090247756 Process for the Preparation of Hexahydroisoquinolines from 1,2,3,4-Tetrahydroisoquinolines
10/01/2009US20090247513 Benzothiophene compounds having antiinfective activity
10/01/2009US20090247506 Antibacterial agents
09/2009
09/30/2009CN101544603A Preparation method of 3,4-dihydropapaverine and hydrochloride thereof
09/29/2009US7595399 Tyrosine derivatives
09/29/2009US7595343 Inhibitors of histone deacetylase
09/29/2009CA2393793C Substituted group 4 metal complexes, catalysts and olefin polymerization process
09/24/2009US20090239841 Diaryl Ureas as CB1 Antagonists
09/23/2009EP2102164A1 Cycloalkylamine substituted isoquinoline and isoquinolinone derivatives
09/23/2009EP2102163A2 Preparation of hexahydroisoquinolines from dihydroisoquinolines
09/23/2009EP2101772A1 Intermediate duration neuromuscular blocking agents and antagonists thereof
09/23/2009EP1467989B1 Proline compounds as ns3-serine protease inhibitors for use in treatment of hepatitis c virus infection
09/22/2009US7592450 used to inhibit proliferative conditions, such as cancer and psoriasis, with improved bioavailability and stability
09/17/2009WO2009113081A1 Tris (hydroxymethyl ) amino methane salt of quinapril and ramipril
09/17/2009WO2009112550A1 Novel n-substituted tetrahydroisoquinoline/isoindoline hydroxamic acid compounds
09/17/2009US20090234126 Process for the Synthesis of Arylamines from the Reaction of an Aromatic Compound with Ammonia or a Metal Amide
09/17/2009US20090233961 Tartrate derivatives for use as coagulation factor ixa inhibitors
09/17/2009US20090233949 Isoserine derivatives for use as coagulation factor ixa inhibitors
09/16/2009EP2100879A1 Novel N-substituted tetrahydroisoquinoline/isoindoline hydroxamic acid compounds
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