Patents for C07D 217 - Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems (11,865) |
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02/14/2008 | US20080039462 Compounds having 5-HT6 receptor affinity |
02/14/2008 | CA2660424A1 Sulfonamide compound or salt thereof |
02/13/2008 | EP1885697A2 Soluble epoxide hydrolase inhibitors and methods of using same |
02/13/2008 | CN100368401C Cyanoguanidine prodrugs |
02/12/2008 | US7329765 Benzothiophene compounds having antiinfective activity |
02/12/2008 | US7329755 especially naphthalene sulfonamides, used for treating asthma |
02/12/2008 | US7329753 Quinoline and isoquinoline derivatives, a process for their production and their use as inflammation inhibitors |
02/12/2008 | US7329749 Piperazinylcarbonylquinolines and -isoquinolines |
02/12/2008 | US7329657 Indazolyl-substituted pyrroline compounds as kinase inhibitors |
02/12/2008 | CA2385996C Anticancer agents |
02/07/2008 | WO2008016913A1 Biologically potent analogues of the dmt-tic pharmacophore and methods of use |
02/07/2008 | US20080033177 Process for the preparation of substituted-1,2,3,4-tetrahydroisoquinoline derivatives |
02/07/2008 | US20080033007 Substituted Tetrahydroisoquinoline Compounds for Cancer Therapy |
02/07/2008 | US20080032997 (5S)-5-methyl-5-({[6-[2-(trifluoromethyl)pyrimidin-5-yl]-3,4-dihydroisoquinolin-2(1H)-yl]sulfonyl}methyl)imidazolidine-2,4-dione; asthma, rhinitis, chronic obstructive pulmonary diseases (COPD), arthritis (such as rheumatoid arthritis and osteoarthritis), atherosclerosis, cancer |
02/07/2008 | US20080032982 2-{2-[3-(4-chlorophenyl)acryloyl]-4-methylphenoxy}-4-phenylbutanoic acid; Peroxisome Proliferator Activated Receptors (PPAR); diabetes, dyslipidemia and/or atherosclerosis |
02/07/2008 | US20080031823 Agents for therapy efficacy monitoring and deep tissue imaging |
02/06/2008 | CN101119970A Azadecalin glucocorticoid receptor modulators |
02/06/2008 | CN101119969A Use of aryl- and heteroaryl-substituted tetrahydroisoquinolines to block reuptake of norepinephrine, dopamine, and serotonin |
02/06/2008 | CN100366612C 4-oxo-3-(1-oxo-1h-isoquinolin-2-ylacetylamino)-pentanoic acid ester and amide derivatives and their use as aspartic specifity cysteine proteinase inhibitors |
02/06/2008 | CN100366611C Substitutional ramification of tetrahydro-isoquinoline, as well as its preparing method and its medication compound containing them |
02/05/2008 | US7326709 e.g. 1-((3-Phenyl-1,2,4-triazolo(3,4-a)phthalazines-6-yl)carbonyl)piperidine; high affinity to the benzodiazepine site of GABAA receptors; central nervous system (CNS) diseases such as depression, anxiety, and attention deficit disorder |
01/31/2008 | WO2008012782A2 Labelled analogues of halobenzamides as radiopharmaceuticals |
01/31/2008 | US20080027115 Combinatorial libraries of autoinducer analogs, autoinducer agonists and antagonists, and methods of use thereof |
01/31/2008 | US20080027050 Heterocyclic Amide Compound and Use Thereof as an Mmp-13 Inhibitor(Amended Ex Officio) |
01/31/2008 | US20080027036 S1P receptor modulating compounds and use thereof |
01/31/2008 | CA2657247A1 Compounds which modulate the cb2 receptor |
01/30/2008 | CN100364978C Composition, process of making, and medical use of substituted 4-phenyltetrahydroisoquinolines |
01/29/2008 | US7323596 Antibacterial or antiprotozoal activity: formula (1) formula (2) wherein: Z represents a radical of formula N(OH)CH( .dbd. O) or of formula C( .dbd. O)NH(OH); R1 represents hydrogen, methyl or trifluoromethyl, or, except when Z is a radical of |
01/29/2008 | US7323475 Adjust concentration of erythropoietin in blood; strokes; antiepileptic agents; liver disorders; antiulcer agents; central nervous system disorders |
01/29/2008 | US7323448 Antibacterial agents |
01/24/2008 | WO2008009215A1 Tetrahydro isoquinoline derivatives, preparation methods and medicinal uses thereof |
01/24/2008 | US20080021201 Protease inhibitor conjugates and antibodies useful in immunoassay |
01/24/2008 | US20080021034 Compositions and methods for modulating gated ion channels |
01/23/2008 | EP1879895A1 Enzyme inhibitors |
01/23/2008 | EP1879867A2 Intermediates for preparing solifenacin |
01/23/2008 | EP1732898B1 Tetrahydroisoquinoline- and tetrahydrobenzazepine derivatives as igf-1r inhibitors |
01/23/2008 | EP1322619B1 Isoquinolinone potassium channel inhibitors |
01/22/2008 | CA2374362C Urea derivatives as hiv aspartyl protease inhibitors |
01/17/2008 | WO2008007780A1 Pentadienamide derivative |
01/17/2008 | WO2008006481A1 Vr1 vanilloid receptor antagonists with a iononic substructure |
01/17/2008 | WO2008006480A1 Biarylcarboxyarylamides as vanilloid-1 receptor modulators |
01/17/2008 | US20080015352 zinc complexed with triiodothyronine; improved potency, stability, absorbability, targeted delivery |
01/17/2008 | US20080015180 Methods and compositions for treating amyloid-related diseases |
01/17/2008 | CA2658097A1 Pentadienamide derivatives |
01/17/2008 | CA2657304A1 Vr1 vanilloid receptor antagonists with a iononic substructure |
01/17/2008 | CA2657300A1 Biarylcarboxyarylamides as vanilloid-1 receptor modulators |
01/16/2008 | EP1877369A2 Inhibitors of microsomal triglyceride transfer protein and apo-b secretion |
01/16/2008 | EP1755593B1 Naphthalene derivatives useful as histamine-3-receptor ligands |
01/16/2008 | EP1392306B1 Substituted tetrahydroisoquinolines for use in the treatment of inflammatory diseases |
01/10/2008 | WO2008005910A2 Pyridone/hydroxypyridine 11-beta hydroxysteroid dehydrogenase type i inhibitors |
01/10/2008 | WO2006134143A8 Process of producing bleach boosters |
01/10/2008 | US20080009627 coordination compounds such as iridium(phenylisoquinoline); high luminous efficiency and stability; low cost production |
01/10/2008 | US20080009489 Androgen receptor modulators and method of treating disease using the same |
01/10/2008 | CA2657702A1 Quinazolines and related heterocyclic comp0unds, and their therapeutic use |
01/09/2008 | EP1402890B1 Sulfonamide derivatives |
01/09/2008 | EP1263730B1 Amine derivatives for the treatment of apoptosis |
01/08/2008 | CA2334298C Neuropeptide y5 receptor antagonists |
01/03/2008 | WO2008001859A1 OPIOID δ RECEPTOR AGONIST |
01/03/2008 | US20080004331 for hepatitis C; histone deacetylase inhibitors; N-hydroxy-4-{[(naphthyl-carbonylamino]alkoxy}benzamides; anticarcinogenic agent; acute promyelocytic leukemia; cell-cycle arrest in late G1 phase or at the G2/M transition |
01/03/2008 | US20080004282 Compositions and methods for modulating gated ion channels |
01/01/2008 | US7314938 Immune and/or inflammatory disorders; autoimmune disorders; disorders mediated by the CD11/CD18 family of cellular adhesion molecules (e.g., LFA-1); antagonize CD11/CD18 receptors associated with leukocytes. |
01/01/2008 | US7314937 Non-imidazole aryl alkylamines compounds as histamine H3 receptor antagonists, preparation and therapeutic uses |
01/01/2008 | US7314879 N-Acylpiperazine derivatives for obesity, diabetes, and erectile dysfunction treatment; sexual disorders |
01/01/2008 | US7314874 N-(5-bromo-2-pyridinyl)-(2-4-[(2-aminosulfonyl)phenyl]phenylcarbonylamino)phenylcarboxamide;modified amidine elements of high potency in vitro, excellent pharmacological and pharmaceutical properties in vivo |
12/27/2007 | WO2007149031A1 Isoquinoline derivatives and their use as inhibitors of cytokine mediated diseases |
12/27/2007 | WO2007148208A2 Carbonylated (aza) cyclohexanes as dopamine d3 receptor ligands |
12/27/2007 | US20070299108 New heterocyclic compounds, their preparation and their use as medicaments, in particular as anti-bacterial agents |
12/27/2007 | US20070299105 2-Cyanopropanoic Acid Amide and Ester Derivatives and Methods of Their Use |
12/27/2007 | US20070299104 Tetrahydropyranyl Cyclopentyl 1-Substituted and 1,1-Disubstituted Tetrahydroisoquinoline Modulators of Chemokine Receptor Activity |
12/27/2007 | US20070299101 Niacin Receptor Agonists, Compositions Containing Such Compounds and Methods of Treatment |
12/27/2007 | US20070299067 Quinoline and isoquinoline derivatives as phosphodiesterase 10 inhibitors |
12/27/2007 | US20070298104 Cyanoisoquinoline compounds and methods of use thereof |
12/27/2007 | CA2655654A1 New carbonylated (aza)cyclohexanes as dopamine d3 receptor ligands |
12/27/2007 | CA2652612A1 Inhibitors of akt (protein kinase b) |
12/26/2007 | EP1870405A1 Carbonylated (Aza)cyclohexanes as dopamine D3 receptor ligands |
12/26/2007 | EP1869001A1 Substituted tetrahydroisochinolines as mmp inhibitors, related production method and use as medicine |
12/26/2007 | EP1689717B1 Substituted isoquinolines useful in the treatment of diseases such as cancer and atherosclerosis |
12/26/2007 | CN101094672A 4-phenyl substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine and serotonin |
12/26/2007 | CN101092395A Method for preparing derivative of 1,4 ¿C dichloro isoquinoline category |
12/26/2007 | CN100357302C Phosphorescent compounds and devices comprising the same |
12/26/2007 | CN100356979C Integrin expression inhibitors |
12/25/2007 | US7312358 Dysmenorrhea; congestive heart failure; liver disorders; vision defects |
12/25/2007 | US7312333 N-heterocyclic hydroxyethylamine compounds; human immunodeficiency virus (HIV) protease |
12/25/2007 | US7312230 Carboxylic acid derivatives as IP antagonists |
12/25/2007 | US7312218 For use as anticoagulant agents for therapy of thromboembolic disorders; 6-chloro-naphthalene-2-sulfonic acid [1-(1-cyclopentyl-piperidin-4-yl)-2-oxo-pyrrolidin-3-yl]-amide; )-2-methyl-benzothiazole-6-sulfonic acid [1-(1-isopropyl-piperidin-4-yl)-2-oxo-pyrrolidin-3-yl]-amide |
12/21/2007 | WO2007144639A1 2 -oxybenzamide derivatives as parp inhibitors |
12/21/2007 | CA2654927A1 Substituted phenyl acetic acids as dp-2 antagonists |
12/20/2007 | US20070293540 for hepatitis C; histone deacetylase inhibitors; N-hydroxy-4-{[(naphthyl-carbonylamino]alkoxy}benzamides; anticarcinogenic agent; acute promyelocytic leukemia; cell-cycle arrest in late G1 phase or at the G2/M transition |
12/20/2007 | US20070293498 used for the treatment of cachexia and other weight loss disorders, such as those resulting from cancer, HIV, old age and anorexia nervosa |
12/20/2007 | US20070292718 Electroluminescent iridium compounds having red-orange or red emission and devices made with such compounds |
12/19/2007 | EP1866298A2 Hydroxysteroid dehydrogenase inhibitors |
12/19/2007 | EP1865775A1 Diarylamine-containing compounds and compositions, and their use as modulators of steroid hormone nuclear receptors |
12/19/2007 | EP1865774A1 Bicycloheteroaryl compounds as p2x7 modulators and uses thereof |
12/19/2007 | EP1601358B1 2,5-substituted tetrahydroisoquinolines for use as 5-ht6 modulators |
12/19/2007 | EP1490062B1 Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof |
12/19/2007 | EP1115693B9 SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL $i(TERTIARY)-HETEROALKYLAMINES USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY |
12/19/2007 | EP1032556B1 Pharmaceutically active compounds and methods of use |
12/19/2007 | CN100355728C Inhibitors of dipeptidyl peptidase IV |
12/18/2007 | US7309708 Serine protease inhibition via N-(distubstituted aminomethylcarbonyl)-2-[N-(1-sulfonylamido-1-cyclopropanyl)amido]pyrrolidines |
12/12/2007 | EP1863764A1 Process for the preparation of opioid modulators |