Patents
Patents for C07D 217 - Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems (11,865)
01/2011
01/12/2011EP2271625A2 Tetrahydroisoquinolines, pharmaceutical compositions containing them, and their use in therapy
01/12/2011EP1987006B1 Novel aminoalcohol-substituted aryldihydroisoquinolinones, process for their preparation and their use as medicaments
01/12/2011EP1869001B1 Substituted tetrahydroisochinolines as mmp inhibitors, related production method and use as medicine
01/12/2011EP1682513B1 Method for producing cyclic, n-substituted alpha-iminocarboxylic acids
01/12/2011CN101945864A Oxadiazole derivatives active on sphingosine-1-phosphate (s1p)
01/12/2011CN101450927B Benzoic acid derivates containing oxo pyridine substituted propionamido
01/12/2011CN101337935B Method for purifying atracurium besylate by two-phase extraction
01/11/2011US7868003 Substituted 4-phenyltetrahydroisoquinolines, pharmaceutical compositions comprising them and therapeutic methods for their use
01/11/2011CA2385592C Benzamides and related inhibitors of factor xa
01/06/2011WO2011002984A1 Substituted phenoxypropylcycloamine derivatives as histamine-3 (h3) receptor ligands
01/06/2011WO2011002684A1 Smac mimetic
01/06/2011WO2011002038A1 Novel diarylamine compound, and anti-aging agent, polymer composition, crosslinked rubber product and molded article thereof, and method for producing diarylamine compound
01/06/2011WO2011001373A1 Process for the preparation of an enantiomerically pure trisubstituted 1,2,3,4-tetrahydroisoquinoline derivative
01/06/2011US20110003992 Mono and bis-ester derivatives of pyridinium and quinolinium compounds as environmentally friendly corrosion inhibitors
01/06/2011US20110003850 Derivatives of 4-(n-azacycloalkyl) anilides as potassium channel modulators
01/06/2011US20110003843 Novel compounds derived from indole and pharmaceutical compositions containing them
01/06/2011US20110003795 Substituted Aromatic Carboxamide and Urea Derivatives as Vanilloid Receptor Ligands
01/05/2011EP2270006A1 Pyridazine derivatives useful as vanilloid receptor ligands
01/05/2011EP2268617A1 Process for the resolution of isoquinoline derivatives
01/05/2011EP1542692B1 Aminopyrimidine derivatives for use as vanilloid receptor ligands for the treatment of pain
01/04/2011US7863292 modulators of hypoxia inducible factors and/or endogenous erythropoietin, such as 1-Chloro-4-hydroxy-7-isopropoxy-isoquinoline-3-carboxylic acid (2-hydroxy-1-hydroxymethyl-ethyl)-amide, used for the treatment of anemic disorders, neurological disorders and/or injuries
01/04/2011CA2306093C Heteroaryl diazacycloalkanes as cholinergic ligands at nicotinic acetylcholine receptors
12/2010
12/29/2010EP2265587A1 Modulators of the histamine h3 receptor useful for the treatment of disorders related thereto
12/29/2010CN101928245A 8-hydroxyl or methoxyl-2-aryl-1-isoquinolines, synthesis method and application thereof
12/29/2010CN101928244A Structural analogue and derivative of isochromanone-4 compound with cardiovascular activity, preparation method and application thereof
12/29/2010CA2765678A1 Substituted hydroxamic acids and uses thereof
12/28/2010US7858792 Biphenyl-2-ylcarbamic Acid 1-(2-{5-[2-(4-Hydroxyphenyl)ethylamino]pentylcarbamoyl}ethyl)piperidin-4-yl Ester, used for the treatment of respiratory system disorders such as chronic obstructive pulmonary disease and asthma
12/28/2010US7858641 melanocortin-4 receptor (MC4-R) agonists such as (3R,5S)-N-(2-{2-[2-fluoro-4-(methyloxy)phenyl]ethyl}-1-oxo-1,2-dihydroisoquinolin-6-yl)-3,5-dimethyl-N'-[(1S,2S,3S,5R)-2,6,6-trimethylbicyclo[3.1.1]hept-3-yl]piperazine-1-carboximidamide, used for the treatment of obesity or diabetes
12/28/2010US7858631 such as (3R,5S)-N-(3-{2-[2-fluoro-4-(methyloxy)phenyl]ethyl}-4-oxo-3,4-dihydropyrido[2,3-d]pyrimidin-7-yl)-3,5-dimethyl-N'-[(1S,2S,3S,5R)-2,6,6-trimethylbicyclo[3.1.1]hept-3-yl]piperazine-1-carboximidamide, used as melanocortin-4 receptor (MC4-R) agonists, for the treatment of obesity or diabetes
12/28/2010US7858620 Cyanoisoquinoline
12/23/2010WO2010146881A1 Substituted isoquinoline derivative
12/23/2010WO2010145206A1 Preparation methods of optical isomers of stepholidine or its derivatives and intermediates thereof
12/23/2010WO2010126626A3 Dual mechanism inhibitors for the treatment of disease
12/23/2010US20100324086 Compounds and methods
12/23/2010US20100324046 4-carboxybenzylamino derivatives as histone deacetylase inhibitors
12/23/2010US20100324025 Antibacterial Agents
12/23/2010US20100324009 Substituted Sulfonamide Compounds
12/23/2010CA2764124A1 Substituted isoquinoline derivative
12/22/2010CN1988907B Dual small molecule inhibitors of cancer and angiogenesis
12/22/2010CN1729158B Adamantyl acetamides as 11-beta hydroxysteroid dehydrogenase inhibitors
12/22/2010CN101921229A Synthesis method of stepholidine or derivative optical isomer thereof and intermediate thereof
12/22/2010CN101497584B Isoquinoline-3-formyl amino acid formyl amino acid benzyl ester, as well as preparation and use thereof
12/21/2010US7855203 Indazolyl-substituted pyrroline compounds as kinase inhibitors
12/21/2010US7855198 Benzamide derivative or salt thereof
12/21/2010CA2483461C Isoquinoline derivatives
12/21/2010CA2401778C Benzamides and related inhibitors of factor xa
12/16/2010US20100317712 Estrogen Agonists/Antagonists For Preventing Breast Cancer
12/16/2010US20100317691 Isoquinolone compounds as subtype-selective agonists for melatonin receptors mt1 and mt2
12/16/2010US20100317644 Substituted Sulfonamide Compounds
12/16/2010US20100314556 1,8-naphthalimide derivatives as scintillation agents, in particular for discriminating between fast neutrons and gamma rays
12/16/2010CA2765053A1 Isoquinoline, quinoline, and quinazoline derivatives as inhibitors of hedgehog signaling
12/15/2010CN1984660B 4-arylamino-quinazolines as activators of aspartic acid specificity cysteine protease and inducers of apoptosis
12/14/2010CA2347100C Novel indenoisoquinolines as antineoplastic agents
12/09/2010WO2010140802A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same
12/09/2010WO2010139953A1 Compounds
12/09/2010US20100311760 Heterocyclic antiviral compounds
12/09/2010US20100311728 Manipulation of brain CDP-diacylglycerol and uses thereof
12/08/2010EP2258360A2 Method for the treatment or prevention of lower urinary tract symptoms
12/08/2010CN101230039B Compound having anti-fouling activity as well as extraction method and use thereof
12/07/2010US7846930 2-Methyl-4-(4-methylsulfanyl-phenyl)-7-(3-piperidin-1-ylmethyl-phenoxy)-1,2,3,4-tetrahydro-isoquinoline, used for the treatment of cognitive disorders, sleep disorders and psychiatric disorders
12/02/2010US20100305325 Process for the preparation of an enantiomeric trisubstituted 3,4-dihydro-isoquinoline derivative
12/02/2010US20100305158 Method for the treatment or prevention of lower urinary tract symptoms
12/01/2010EP2256105A1 Novel tetrahydroisoquinoline derivative
12/01/2010EP2102164B1 Cycloalkylamine substituted isoquinoline and isoquinolinone derivatives
12/01/2010CN101903335A Amine linked modulators of gamma-secretase
12/01/2010CN101898982A Npy y5 antagonists
11/2010
11/30/2010US7842703 Pain therapy; headaches; neurodegenerative diseases; stroke; skin disorders; antiischemic agents; Huntington's disease; antiulcer agents; inflammatory bowel disorders;amyotropic lateral sclerosis
11/30/2010CA2477208C Substituted phenylalkanoic acid derivatives and use thereof
11/30/2010CA2450076C Anthranilic acid amides with a heteroarylsulfonyl side chain, method for the production thereof, use thereof as a medicament or a diagnostic agent and pharmaceutical preparations containing said compounds
11/25/2010WO2010133748A1 Protease inhibitors
11/25/2010WO2010133647A1 Isoquinolin-1 (2h) -one derivatives as parp-1 inhibitors
11/25/2010US20100298570 Process for the resolution of isoquinoline derivatives
11/25/2010US20100298374 Nitrile derivatives and their pharmaceutical use and compositions
11/25/2010US20100298373 Oxadiazole derivatives active on sphingosine-1-phosphate (sip)
11/25/2010US20100298285 Biclycloheteroaryl Compounds as P2x7 Modulators and Uses Thereof
11/25/2010US20100298284 Benzamides and related inhibitors of factor xa
11/25/2010CA2762427A1 Nitrile derivatives and their pharmaceutical use and compositions
11/25/2010CA2762226A1 Isoquinolin-1 (2h) -one derivatives as parp-1 inhibitors
11/25/2010CA2758222A1 Protease inhibitors
11/24/2010EP2253328A1 Cycloalkyl inhibitors of potassium channel function
11/24/2010EP2253315A1 Alkoxyphenylpropanoic acid derivatives
11/24/2010EP2252589A2 6-and 7-amino isoquinoline compounds and methods for making and using the same
11/24/2010CN101896462A Process for the resolution of isoquinoline derivatives
11/18/2010US20100292500 Npy y5 antagonist
11/18/2010US20100292242 Aryl, heteroaryl, and heterocycle substituted tetrahydroisoquinolines and use thereof
11/18/2010US20100292235 Bicycloheteroaryl Compounds as P2x7 Modulators and Uses Thereof
11/17/2010EP2251324A1 Heteroaryl-alkylcarbamate compounds and their use as inhibitors of the faah enzyme
11/17/2010EP1994006B1 Polymerisation of ethylene and alpha-olefins with imino-quinolinol complexes
11/17/2010CN101888999A Pyridylmethyl-sulfonamide compounds
11/16/2010US7834184 Changing the substitution pattern on the aromatic ring of the pre-Grewe intermediate; 4-chloro-5-((1,2,3,4,5,8-hexahydro-6-methoxyisoquinolin-1-yl)methyl)benzene-1,2-diol; 4-chloro-5-(((R)-1,2,3,4,5,8-hexahydro-6-methoxyisoquinolin-1-yl)methyl)benzene-1,2-diol
11/16/2010US7834054 Hydroxamates as therapeutic agents
11/16/2010US7834049 Integrin expression inhibitor
11/16/2010US7834047 Arylsulfonamides and uses related thereto
11/16/2010US7834012 Pharmaceutical compositions as inhibitors of dipeptidyl peptidase-IV (DPP-IV)
11/16/2010US7833999 histamine H3 receptor modulators; obesity, diabetes and central nervous system diseases such as vigilance and sleep disorders; e.g. (+)-2-(cyclohexylmethyl)-N-[2-(1-methylpyrrolidin-2-yl)ethyl] -1,2,3 ,4-tetrahydroisoquinoline-7-sulfonamide
11/16/2010CA2477474C Cyclic n-substituted alpha imino carboxylic acids for selective inhibition of collagenase
11/11/2010WO2010127608A1 Heterocyclic substituted acardite derivates and use thereof
11/11/2010US20100286198 Biofilm-Inhibiting Effect and Anti-Infective Activity of N,C- Linked Arylisoquinolines and the Use Thereof
11/11/2010US20100286197 Carboxamide Derivatives As Therapeutic Agents
11/11/2010US20100286196 New inhibitor of dd-peptidase and its use as antibiotic or anticancer drug
1 ... 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 ... 119