Patents for C07D 217 - Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems (11,865) |
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01/12/2011 | EP2271625A2 Tetrahydroisoquinolines, pharmaceutical compositions containing them, and their use in therapy |
01/12/2011 | EP1987006B1 Novel aminoalcohol-substituted aryldihydroisoquinolinones, process for their preparation and their use as medicaments |
01/12/2011 | EP1869001B1 Substituted tetrahydroisochinolines as mmp inhibitors, related production method and use as medicine |
01/12/2011 | EP1682513B1 Method for producing cyclic, n-substituted alpha-iminocarboxylic acids |
01/12/2011 | CN101945864A Oxadiazole derivatives active on sphingosine-1-phosphate (s1p) |
01/12/2011 | CN101450927B Benzoic acid derivates containing oxo pyridine substituted propionamido |
01/12/2011 | CN101337935B Method for purifying atracurium besylate by two-phase extraction |
01/11/2011 | US7868003 Substituted 4-phenyltetrahydroisoquinolines, pharmaceutical compositions comprising them and therapeutic methods for their use |
01/11/2011 | CA2385592C Benzamides and related inhibitors of factor xa |
01/06/2011 | WO2011002984A1 Substituted phenoxypropylcycloamine derivatives as histamine-3 (h3) receptor ligands |
01/06/2011 | WO2011002684A1 Smac mimetic |
01/06/2011 | WO2011002038A1 Novel diarylamine compound, and anti-aging agent, polymer composition, crosslinked rubber product and molded article thereof, and method for producing diarylamine compound |
01/06/2011 | WO2011001373A1 Process for the preparation of an enantiomerically pure trisubstituted 1,2,3,4-tetrahydroisoquinoline derivative |
01/06/2011 | US20110003992 Mono and bis-ester derivatives of pyridinium and quinolinium compounds as environmentally friendly corrosion inhibitors |
01/06/2011 | US20110003850 Derivatives of 4-(n-azacycloalkyl) anilides as potassium channel modulators |
01/06/2011 | US20110003843 Novel compounds derived from indole and pharmaceutical compositions containing them |
01/06/2011 | US20110003795 Substituted Aromatic Carboxamide and Urea Derivatives as Vanilloid Receptor Ligands |
01/05/2011 | EP2270006A1 Pyridazine derivatives useful as vanilloid receptor ligands |
01/05/2011 | EP2268617A1 Process for the resolution of isoquinoline derivatives |
01/05/2011 | EP1542692B1 Aminopyrimidine derivatives for use as vanilloid receptor ligands for the treatment of pain |
01/04/2011 | US7863292 modulators of hypoxia inducible factors and/or endogenous erythropoietin, such as 1-Chloro-4-hydroxy-7-isopropoxy-isoquinoline-3-carboxylic acid (2-hydroxy-1-hydroxymethyl-ethyl)-amide, used for the treatment of anemic disorders, neurological disorders and/or injuries |
01/04/2011 | CA2306093C Heteroaryl diazacycloalkanes as cholinergic ligands at nicotinic acetylcholine receptors |
12/29/2010 | EP2265587A1 Modulators of the histamine h3 receptor useful for the treatment of disorders related thereto |
12/29/2010 | CN101928245A 8-hydroxyl or methoxyl-2-aryl-1-isoquinolines, synthesis method and application thereof |
12/29/2010 | CN101928244A Structural analogue and derivative of isochromanone-4 compound with cardiovascular activity, preparation method and application thereof |
12/29/2010 | CA2765678A1 Substituted hydroxamic acids and uses thereof |
12/28/2010 | US7858792 Biphenyl-2-ylcarbamic Acid 1-(2-{5-[2-(4-Hydroxyphenyl)ethylamino]pentylcarbamoyl}ethyl)piperidin-4-yl Ester, used for the treatment of respiratory system disorders such as chronic obstructive pulmonary disease and asthma |
12/28/2010 | US7858641 melanocortin-4 receptor (MC4-R) agonists such as (3R,5S)-N-(2-{2-[2-fluoro-4-(methyloxy)phenyl]ethyl}-1-oxo-1,2-dihydroisoquinolin-6-yl)-3,5-dimethyl-N'-[(1S,2S,3S,5R)-2,6,6-trimethylbicyclo[3.1.1]hept-3-yl]piperazine-1-carboximidamide, used for the treatment of obesity or diabetes |
12/28/2010 | US7858631 such as (3R,5S)-N-(3-{2-[2-fluoro-4-(methyloxy)phenyl]ethyl}-4-oxo-3,4-dihydropyrido[2,3-d]pyrimidin-7-yl)-3,5-dimethyl-N'-[(1S,2S,3S,5R)-2,6,6-trimethylbicyclo[3.1.1]hept-3-yl]piperazine-1-carboximidamide, used as melanocortin-4 receptor (MC4-R) agonists, for the treatment of obesity or diabetes |
12/28/2010 | US7858620 Cyanoisoquinoline |
12/23/2010 | WO2010146881A1 Substituted isoquinoline derivative |
12/23/2010 | WO2010145206A1 Preparation methods of optical isomers of stepholidine or its derivatives and intermediates thereof |
12/23/2010 | WO2010126626A3 Dual mechanism inhibitors for the treatment of disease |
12/23/2010 | US20100324086 Compounds and methods |
12/23/2010 | US20100324046 4-carboxybenzylamino derivatives as histone deacetylase inhibitors |
12/23/2010 | US20100324025 Antibacterial Agents |
12/23/2010 | US20100324009 Substituted Sulfonamide Compounds |
12/23/2010 | CA2764124A1 Substituted isoquinoline derivative |
12/22/2010 | CN1988907B Dual small molecule inhibitors of cancer and angiogenesis |
12/22/2010 | CN1729158B Adamantyl acetamides as 11-beta hydroxysteroid dehydrogenase inhibitors |
12/22/2010 | CN101921229A Synthesis method of stepholidine or derivative optical isomer thereof and intermediate thereof |
12/22/2010 | CN101497584B Isoquinoline-3-formyl amino acid formyl amino acid benzyl ester, as well as preparation and use thereof |
12/21/2010 | US7855203 Indazolyl-substituted pyrroline compounds as kinase inhibitors |
12/21/2010 | US7855198 Benzamide derivative or salt thereof |
12/21/2010 | CA2483461C Isoquinoline derivatives |
12/21/2010 | CA2401778C Benzamides and related inhibitors of factor xa |
12/16/2010 | US20100317712 Estrogen Agonists/Antagonists For Preventing Breast Cancer |
12/16/2010 | US20100317691 Isoquinolone compounds as subtype-selective agonists for melatonin receptors mt1 and mt2 |
12/16/2010 | US20100317644 Substituted Sulfonamide Compounds |
12/16/2010 | US20100314556 1,8-naphthalimide derivatives as scintillation agents, in particular for discriminating between fast neutrons and gamma rays |
12/16/2010 | CA2765053A1 Isoquinoline, quinoline, and quinazoline derivatives as inhibitors of hedgehog signaling |
12/15/2010 | CN1984660B 4-arylamino-quinazolines as activators of aspartic acid specificity cysteine protease and inducers of apoptosis |
12/14/2010 | CA2347100C Novel indenoisoquinolines as antineoplastic agents |
12/09/2010 | WO2010140802A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same |
12/09/2010 | WO2010139953A1 Compounds |
12/09/2010 | US20100311760 Heterocyclic antiviral compounds |
12/09/2010 | US20100311728 Manipulation of brain CDP-diacylglycerol and uses thereof |
12/08/2010 | EP2258360A2 Method for the treatment or prevention of lower urinary tract symptoms |
12/08/2010 | CN101230039B Compound having anti-fouling activity as well as extraction method and use thereof |
12/07/2010 | US7846930 2-Methyl-4-(4-methylsulfanyl-phenyl)-7-(3-piperidin-1-ylmethyl-phenoxy)-1,2,3,4-tetrahydro-isoquinoline, used for the treatment of cognitive disorders, sleep disorders and psychiatric disorders |
12/02/2010 | US20100305325 Process for the preparation of an enantiomeric trisubstituted 3,4-dihydro-isoquinoline derivative |
12/02/2010 | US20100305158 Method for the treatment or prevention of lower urinary tract symptoms |
12/01/2010 | EP2256105A1 Novel tetrahydroisoquinoline derivative |
12/01/2010 | EP2102164B1 Cycloalkylamine substituted isoquinoline and isoquinolinone derivatives |
12/01/2010 | CN101903335A Amine linked modulators of gamma-secretase |
12/01/2010 | CN101898982A Npy y5 antagonists |
11/30/2010 | US7842703 Pain therapy; headaches; neurodegenerative diseases; stroke; skin disorders; antiischemic agents; Huntington's disease; antiulcer agents; inflammatory bowel disorders;amyotropic lateral sclerosis |
11/30/2010 | CA2477208C Substituted phenylalkanoic acid derivatives and use thereof |
11/30/2010 | CA2450076C Anthranilic acid amides with a heteroarylsulfonyl side chain, method for the production thereof, use thereof as a medicament or a diagnostic agent and pharmaceutical preparations containing said compounds |
11/25/2010 | WO2010133748A1 Protease inhibitors |
11/25/2010 | WO2010133647A1 Isoquinolin-1 (2h) -one derivatives as parp-1 inhibitors |
11/25/2010 | US20100298570 Process for the resolution of isoquinoline derivatives |
11/25/2010 | US20100298374 Nitrile derivatives and their pharmaceutical use and compositions |
11/25/2010 | US20100298373 Oxadiazole derivatives active on sphingosine-1-phosphate (sip) |
11/25/2010 | US20100298285 Biclycloheteroaryl Compounds as P2x7 Modulators and Uses Thereof |
11/25/2010 | US20100298284 Benzamides and related inhibitors of factor xa |
11/25/2010 | CA2762427A1 Nitrile derivatives and their pharmaceutical use and compositions |
11/25/2010 | CA2762226A1 Isoquinolin-1 (2h) -one derivatives as parp-1 inhibitors |
11/25/2010 | CA2758222A1 Protease inhibitors |
11/24/2010 | EP2253328A1 Cycloalkyl inhibitors of potassium channel function |
11/24/2010 | EP2253315A1 Alkoxyphenylpropanoic acid derivatives |
11/24/2010 | EP2252589A2 6-and 7-amino isoquinoline compounds and methods for making and using the same |
11/24/2010 | CN101896462A Process for the resolution of isoquinoline derivatives |
11/18/2010 | US20100292500 Npy y5 antagonist |
11/18/2010 | US20100292242 Aryl, heteroaryl, and heterocycle substituted tetrahydroisoquinolines and use thereof |
11/18/2010 | US20100292235 Bicycloheteroaryl Compounds as P2x7 Modulators and Uses Thereof |
11/17/2010 | EP2251324A1 Heteroaryl-alkylcarbamate compounds and their use as inhibitors of the faah enzyme |
11/17/2010 | EP1994006B1 Polymerisation of ethylene and alpha-olefins with imino-quinolinol complexes |
11/17/2010 | CN101888999A Pyridylmethyl-sulfonamide compounds |
11/16/2010 | US7834184 Changing the substitution pattern on the aromatic ring of the pre-Grewe intermediate; 4-chloro-5-((1,2,3,4,5,8-hexahydro-6-methoxyisoquinolin-1-yl)methyl)benzene-1,2-diol; 4-chloro-5-(((R)-1,2,3,4,5,8-hexahydro-6-methoxyisoquinolin-1-yl)methyl)benzene-1,2-diol |
11/16/2010 | US7834054 Hydroxamates as therapeutic agents |
11/16/2010 | US7834049 Integrin expression inhibitor |
11/16/2010 | US7834047 Arylsulfonamides and uses related thereto |
11/16/2010 | US7834012 Pharmaceutical compositions as inhibitors of dipeptidyl peptidase-IV (DPP-IV) |
11/16/2010 | US7833999 histamine H3 receptor modulators; obesity, diabetes and central nervous system diseases such as vigilance and sleep disorders; e.g. (+)-2-(cyclohexylmethyl)-N-[2-(1-methylpyrrolidin-2-yl)ethyl] -1,2,3 ,4-tetrahydroisoquinoline-7-sulfonamide |
11/16/2010 | CA2477474C Cyclic n-substituted alpha imino carboxylic acids for selective inhibition of collagenase |
11/11/2010 | WO2010127608A1 Heterocyclic substituted acardite derivates and use thereof |
11/11/2010 | US20100286198 Biofilm-Inhibiting Effect and Anti-Infective Activity of N,C- Linked Arylisoquinolines and the Use Thereof |
11/11/2010 | US20100286197 Carboxamide Derivatives As Therapeutic Agents |
11/11/2010 | US20100286196 New inhibitor of dd-peptidase and its use as antibiotic or anticancer drug |