Patents for C07B 53 - Asymmetric syntheses (6,231)
12/1997
12/18/1997WO1997047628A1 Chiral organoboranes
12/18/1997CA2258018A1 Asymmetric synthesis catalyzed by transition metal complexes with cyclic chiral phosphine ligands
12/18/1997CA2257678A1 Chiral organoboranes
12/16/1997US5698741 Hiv reverse transcriptase inhibitor
12/10/1997EP0811630A2 Chiral compounds
12/09/1997US5696254 Processes for the diastereoselective synthesis of nucleoside analogues
12/03/1997EP0809647A1 Chiral organometallic compounds
12/02/1997US5693820 Ruthenium complexes with a chiral, bidentate phosphine/oxazoline ligand for enantioselective transfer hydrogenation of prochiral ketones
12/02/1997US5693816 Reacting sodium borohydride and boron trichloride with alpha-pinene; for reducing prochiral ketone to corresponding alcohol
12/02/1997US5693805 Sulfonamidation of chlorosulfonylcamphor with piperazine derivative salt, oximation, reduction, selective amidation of endo amine isomer, salt formation; tocolytic agents
12/02/1997US5693787 Stereospecific
11/1997
11/25/1997CA2134096C Enantioselective oxazaborolidine catalysts
11/18/1997US5688990 Forming chemical intermediates for azetidinone compounds that inhibit cholesterol biosynthesis for prevention of atherosclerosis
11/18/1997US5688985 Reacting n,n-dibenzylaminophenylalanine ester with acetonitrile in presence of an organometallic catalyst
11/13/1997WO1997042186A1 Process for preparation of pyrimidine derivatives
11/12/1997CN1164530A Amino alcohol derivative and method for preparing the same
11/11/1997US5686616 Process for preparing an optically active amine
11/11/1997US5686615 Stereoselective preparation of substituted piperidines
11/04/1997US5684185 Process for the stereoselective synthesis of 3-substituted 2-sulfonylmethylpropionic acids, and intermediate products
10/1997
10/30/1997WO1997040008A1 Process for preparing pyrrolidine derivatives
10/30/1997DE19617941A1 Novel chiral amphiphilic N-carbonyl-pyrrolidone ligands-prepared by simplified method and useful in preparing metal complexes which catalyse hydrogenation reactions in water
10/30/1997DE19617939A1 Chiral amphiphilic compounds used as e.g. surfactants, emulsifiers or aqueous hydrogenation reaction auxiliary aids
10/29/1997EP0803510A1 2,2'-Disubstituted 1,1'-diphosphino ferrocenes and 1',2'-disubstituted 1-phosphino ferrocenes, their preparation and use and transition metal complexes containing them
10/29/1997EP0724552B1 Process for preparing a chiral tetralone
10/22/1997EP0763005A4 TETRAHYDROINDENO[1,2-d][1,3,2]OXAZABOROLES AND THEIR USE AS ENANTIOSELECTIVE CATALYSTS
10/21/1997US5679857 Subjecting amide formed from l-amino acid and optically active (s)-alpha-alkylbenzylamine to dehydration condensation with aryl aldehyde, racemizing in solvent containing base, hydrolyzing under acidic conditions
10/21/1997CA2116464C Process for the preparation of an optically pure aminoalcohol
10/15/1997EP0801057A1 Process for producing optically active trans-vinyl sulfide alcohols
10/15/1997EP0594608B1 Chiral catalysts for enantioselective synthesis
10/07/1997CA2009637C Substituted-1,3-oxathiolanes with antiviral properties
10/02/1997WO1997035841A2 Method for obtaining pure enantiomers of a pyridazinone derivative
09/1997
09/25/1997WO1997034852A1 Cycloalkyl derivatives and the solid-phase synthesis of such derivatives
09/25/1997CA2248600A1 Cycloalkyl derivatives and the solid-phase synthesis of such derivatives
09/24/1997EP0796239A1 Process for the preparation of enantiomerically pure (s,s) aminoepoxides, key intermediates for hiv protease inhibitors, via their chlorohydrines
09/23/1997US5670652 Method of producing optically active, 4-substituted (S)-2-oxazolidinones
09/23/1997CA2069024C Processes for the diastereoselective synthesis of nucleosides
09/18/1997DE19610103A1 Cycloalkylderivate und ihre Synthese an fester Phase Cycloalkyl derivatives and their synthesis on solid phase
09/17/1997CN1159810A Novel process for the preparation of diisopinocampheylchloroborane
09/11/1997DE19704273A1 Producing optically active alpha-hydroxy-ketone(s), useful in synthesis
09/10/1997EP0794181A1 Asymmetric epoxidation using a titanium-containing zeolite and a chiral hydroperoxide
09/10/1997CN1159185A Method for producing beta-amino alcohol
09/10/1997CN1159184A Racemisation and asymmetric transformation process used in manufacture of levobupivacaine and analogues thereof
09/09/1997US5665890 Chemical synthesis comprising reacting a nucleophile and a chiral or prochiral cyclic substrate
09/02/1997US5663410 Cis-4-(2,2,3,3-tetrafluoropropoxy)-cinnamonitrile and trans-4-(2,2,3,3-tetrafluoropropoxy)-cinnamonitrile and a process for their preparation
09/02/1997US5663384 Asymetric epoxidation using a titanium-containing zeolite and a chiral hydroperoxide
09/02/1997US5663348 Reduction of diketone with aminoalkoxyborane complex to form dialcohol ester compound
09/02/1997US5663320 Processes for the diastereoselective separation of nucleoside analogue synthetic intermediates
08/1997
08/27/1997EP0790998A1 Azo derivatives of 5-aminosalicylic acid for treatment of inflammatory bowel disease
08/26/1997CA2124454C Process for preparing ketone enantiomer
08/19/1997US5659085 Cyclobutenedione derivative, process for preparing the same, and nonlinear optical element
08/19/1997US5659075 Multistep reaction using hindered hydroborating agent for stereospecific 4-amino-2-hydroxymethyl-1-cyclopentanol
08/14/1997WO1997029086A1 Method for the asymmetrical synthesis of s-acylated derivatives of 2-mercaptomethyl 3-phenyl propanoic acid, and use thereof for synthesising n-(mercaptoacyl) amino acid derivatives
08/13/1997EP0788472A1 A process for the preparation of 5,6-dihydroxy-2-amino-1,2,3,4-tetrahydronaphthalene derivatives
08/07/1997WO1997028105A1 Processes for the reduction of carbonyl compounds
08/07/1997CA2216537A1 Process for reduction of carbonyl compounds
08/06/1997EP0787718A1 Process for preparing optically active 4-hydroxy-2-pyrrolidone
08/06/1997EP0787115A1 PROCESS FOR PRODUCING DERIVATIVES OF 4a,5,9,10,11,12,-HEXAHYDRO-6H-BENZOFURO 3a,3,2-ef] 2]BENZAZEPINE
08/06/1997CN1035555C Process for diastereoselective synthesis of nucleosides
08/05/1997US5654338 Preparation of optically active α-(hydroxyphenoxy)alkanecarboxylic acids and derivatives thereof
07/1997
07/23/1997EP0785198A1 Method for the preparation of optically active 3-hydroxyquinuclidine
07/15/1997US5648548 Hydrogenation
07/15/1997CA2069063C Processes for the diastereoselective synthesis of nucleosides
07/09/1997EP0782992A1 Amino alcohol derivative and method for preparing the same
07/09/1997EP0782990A1 Process for the preparation of optically pure 1,2,3,4-Tetrahydro-3-isoquinoline-carboxylic acid and its derivatives
07/09/1997EP0782569A1 Racemisation and asymmetric transformation processes used in the manufacture of levobupivacaine and analogues thereof
07/02/1997EP0781750A2 Asymmetric synthesis of alpha-cycloalkylalkyl substituted methanamines
07/02/1997EP0781749A2 Process for producing optically active benzhydrol compounds
06/1997
06/25/1997EP0780157A1 Ruthenium complex with chiral bidentate phosphinoxazolin ligands for the enantioselective transfer hydrogenation of prochiral cetons
06/18/1997EP0778827A1 Process for producing a beta-amino alcohol
06/18/1997EP0655994B1 Chemical process for preparing an optically active aminodiol
06/17/1997US5639878 Reacting azetidinone derivative containing thio group with n-haloacylimide in the presence of an organic acid
06/12/1997CA2192417A1 Asymmetric synthesis of ó-cycloalkylalkyl substituted methanamines
06/11/1997CN1151735A Benzocycloalkylazolethione derivatives
06/10/1997US5637701 Process for preparing optically active amide derivatives
06/10/1997US5637624 Ring-substituted 2-amino-1,2,3,4-tetrahydronaphthalenes and 3-aminochromanes
06/05/1997WO1997019920A1 Preparation of chiral 3-hydroxy-2-pyrrolidinone derivatives
06/04/1997EP0631571B1 Preparation of optically active hydrazines and amines
05/1997
05/28/1997EP0775146A1 Novel process for the preparation of diisopinocampheylchloroborane
05/28/1997EP0641330A4 Gaba and l-glutamic acid analogs for antiseizure treatment.
05/28/1997EP0592552B1 Chiral phospholanes via chiral 1,4-diol cyclic sulfates
05/27/1997US5633405 Reacting substituted norephedrine with cyclopropylacetylene and lithiating agent in aprotic solvent, mixing with aniline trifluoromethyl ketone, quenching with proton source
05/27/1997US5633373 Enantioselective synthesis of antifolates
05/21/1997EP0774452A1 Optically active compounds having plural chiral centers and the production thereof
05/15/1997WO1997017342A1 A process of making 3-phenyl-1-methylenedioxyphenyl-indane-2-carboxylic acid derivatives
05/15/1997WO1997017341A1 A process of making 3-phenyl-1-methylenedioxyphenyl-indane-2-carboxylic acid derivatives
05/14/1997EP0773213A2 Method for the preparation of methyl (2RS,3RS)-3-(2'-aminophenylthio)-2-hydroxy-3-(4"-methoxyphenyl)propionate
05/13/1997US5629423 Asymmetric synthesis of chiral secondary alcohols
05/09/1997WO1997016421A1 Process for producing optically active trans-vinyl sulfide alcohols
05/09/1997CA2209102A1 Production method of optically active trans-vinylsulfide alcohol
05/06/1997US5627293 Hydrogenation of double and triple bonds after reaction of butyllithium with iron complex
05/06/1997US5627282 Process for the preparation of optically pure 1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid and its derivatives
05/06/1997US5627176 Substituted azetidinone compounds useful as hypocholesterolemic agents
05/02/1997EP0770606A1 Cis-epoxide derivate useful as irreversible HIV protease inhibitor and process for its preparation
05/02/1997EP0770057A1 Method for producing calcium salts of [s,s]-ethylenediamine-n,n'-disuccinic acid
05/02/1997EP0770056A1 A process for producing [s,s]-ethylenediamine-n,n'-disuccinic acid
05/02/1997EP0770054A1 A method for producing [s,s]-ethylenediamine-n,n'-disuccinic acid from its calcium salt
04/1997
04/29/1997US5625066 Optically active hydroquinine (amino-3 phenyl)-1 ethanesulfonate, preparation and use thereof
04/29/1997US5625065 Stereoselective process for making endo-tropanamine and like compounds
04/24/1997WO1997014669A1 Process for preparing optically active carboxylic acids
04/24/1997WO1997014500A1 Chiral solid catalyst, its preparation and its use for the production of substantially enantiomerically pure products
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