Patents for C07B 53 - Asymmetric syntheses (6,231)
11/1995
11/02/1995WO1995029147A1 A process for the preparation of 5,6-dihydroxy-2-amino-1,2,3,4-tetrahydronaphthalene derivatives
11/02/1995WO1995029146A1 Asymmetric synthesis of (r)- and (s)-arylethanolamines from iminoketones
11/02/1995EP0679629A1 Process for preparing optically active alpha-(hydroxy-phenoxy)alkane carboxylic acid and its derivatives
11/02/1995CA2188759A1 A process for the preparation of 5,6-dihydroxy-2-amino-1,2,3,4-tetrahydronaphthalene derivatives
11/02/1995CA2188748A1 Benzocycloalkylazolethione derivatives
11/02/1995CA2188027A1 Asymmetric synthesis of (r)- and (s)-arylethanolamines from iminoketones
10/1995
10/31/1995US5463097 Enantioselective hydrogenation catalysts
10/24/1995US5461156 Stereocontrolled synthesis of cis-bicyclic compounds
10/19/1995WO1995027694A1 PROCESS FOR PRODUCING α,β-DISUBSTITUTED ALCOHOL DERIVATIVE
10/18/1995EP0677291A2 Composition and method containing optically pure (S) metoprolol
10/13/1995CA2146818A1 Pipecolic acid derivatives; process for preparing them and their use as synthesis intermediates
10/11/1995EP0675898A1 Use of molecularly imprinted polymers for stereo- and/or regioselective synthesis
10/10/1995US5457219 Phosphorus compounds
10/05/1995WO1995026334A1 Substituted azetidinone compounds useful as hypocholesterolemic agents
10/04/1995EP0674634A1 Process for preparing substituted 1,3-oxathiolanes with antiviral properties
10/04/1995EP0674618A1 Asymmetric process for preparing florfenicol, thiamphenicol, chloramphenicol and oxazoline intermediates
10/04/1995CN1109470A Asymmetric synthesis
09/1995
09/28/1995WO1995025714A1 Synthesis of compounds with predetermined chirality
09/28/1995CA2184500A1 Synthesis of compounds with predetermined chirality
09/27/1995EP0673911A1 Process for producing optically active carboxylic acids and chiral ligands for this purpose
09/27/1995EP0395729B1 Ligand-accelerated catalytic asymmetric dihydroxylation
09/19/1995US5451684 Asymmetric hydrogenation of furoimidazole derivatives
09/14/1995WO1995024366A1 Process for the preparation of optically active cycloolefins
09/14/1995CA2184353A1 Process for the preparation of optically active cycloolefins
09/13/1995EP0671405A1 Manufacture of esters of 2-keto-L-gulonic acid
09/13/1995EP0670839A1 Process for the preparation of 9-amino camptothecin
09/12/1995US5449694 (-)-ritodrine, therapeutic compositions and use, and method of preparation
08/1995
08/31/1995WO1995023139A1 Optically pure 4-aryl-2-hydroxytetronic acids
08/31/1995CA2184068A1 Optically pure 4-aryl-2-hydroxytetronic acids
08/29/1995US5446175 Optically active compounds and a method for producing them
08/29/1995US5446158 Process for synthesis of FK-506 and tricarbonyl intermediates
08/24/1995WO1995022405A1 Water-soluble chiral sulfonated binap catalyst for asymmetric synthesis of optically active compounds
08/23/1995EP0668259A1 A method for the preparation of optically active 2-aryl alkyl aldehydes and formation of 2-aryl-alkanoic acids therefrom
08/23/1995CN1107135A Glutaric acid derivatives and preparation thereof
08/22/1995US5444155 Molecules with antibody combining sites that induce asymmetry
08/19/1995CA2142655A1 Method for the preparation of optically active 2-aryl alkyl aldehydes and formation of 2-aryl-alkanoic acids therefrom
08/16/1995EP0667350A1 Water-soluble phosphine-derivatives
08/16/1995EP0666905A1 Molecules with antibody combining sites that induce asymmetry
08/15/1995US5442119 Catalytic asymmetric reduction of trisubstituted olefins
08/15/1995US5442118 Asymmetric synthesis of (R)- and (S)-arylethanolamines from iminoketones
08/02/1995EP0664799A1 Amide derivatives
08/02/1995CN1106002A Hydrogenation process
07/1995
07/19/1995EP0663382A1 Process for preparing optically active succinic acid compound
07/19/1995EP0662952A1 Process for the stereoselective synthesis of 3-substituted 2-sulphonyl methyl propionic acids and intermediate products
07/19/1995EP0662951A1 Process for the stereoselective synthesis of 3-substituted 2-thiomethyl propionic acids
07/18/1995US5434302 Amines, lithium base
07/18/1995US5434289 Process for producing optically active β-hydroxyketone
07/18/1995US5434281 Process for the stereospecific synthesis of leukotriene B4 in its 6Z, 8E, 10E configuration and intermediates
07/18/1995CA1336348C Process for industrial synthesis of perindopril and its major synthesis intermediates
07/11/1995US5432289 Diphosphines containing silane groups, immobilized diphosphines and the use thereof as hydrogenation catalysts
07/06/1995WO1995018134A1 Improvements in or relating to chiral syntheses
07/06/1995WO1995018112A1 Improvements in or relating to chiral auxiliaries
07/04/1995US5430191 Assymetric hydrogenation catalysts, enantioselective hydrogen displacement
06/1995
06/28/1995EP0659184A1 Optically active hydroquinine (amino-3 phenyl)-1 ethanesulfonate, preparation and use thereof.
06/21/1995EP0658532A1 Ligand-accelerated catalytic asymmetric dihydroxylation
06/20/1995US5426223 Hydrogenation of n-acyl hydrazones in presence of catalyst comprising complex pf transition metal bonded to phosphine ligands
06/14/1995EP0657439A1 Process improvement in the synthesis of [R-(R*,R*)]-5-(3-chlorophenyl)-3-(2-(3,4-dihydroxyphenyl)-1-methylethyl)-2-oxazolididone
06/14/1995EP0657425A1 Process for the preparation of chiral aminoalcohols
06/13/1995US5424446 Process for preparing optically active 4-mercapto-2-pyrrolidone derivative and intermediate therefor
06/08/1995WO1995015299A1 Process for preparing a chiral tetralone
06/07/1995EP0656335A1 Process for the production of hydroxy compounds by hydrogenation of oxygenates
06/07/1995EP0656334A1 Process for the production of cydohexanedimethanol, with preponderance of the trans-isomer
06/07/1995EP0655994A1 Chemical process for preparing an optically active aminodiol.
06/07/1995EP0655950A1 Chiral catalysts and epoxidation reactions catalyzed thereby.
05/1995
05/30/1995US5420319 Cis-oxalato(trans-1-1,2-cyclohexanediamine) Pt(II) complex having high optical purity and process of preparing same
05/30/1995US5420306 Enantioselective hydrogenation of gamma-keto acid, ruthenium-phosphine catalyst
05/16/1995CA2068532C Preparation of mixtures of cypermethrin or cyfluthrin isomers enriched in more active species
05/10/1995CN1028361C Glutaric acid derivatives and preparations thereof
05/03/1995EP0650965A1 Asymmetric synthesis of (S)-(+)-N,N-dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine an intermediate in the preparation of duloxetine
05/02/1995US5412119 Method of preparing vicinal aminoalcohols
05/02/1995US5411877 Optically active compounding having plural chiral centers and production thereof
04/1995
04/19/1995EP0648201A1 Enantioselective hydrogenation of the carbonyl bond using ruthenium complexes with biphosphine ligands.
04/13/1995DE4334235A1 Optically active oxygen- and sulphur-containing heterocycles, and a process for their preparation
04/12/1995EP0647647A1 Tertiary phosphine compound and transition metal complex comprising the same as ligand
04/12/1995EP0647633A1 Method of preparing a heterocyclic intermediate for the production of optically active aryloxysubstituted vicinal aminoalcohols
04/11/1995US5406004 Hydrogenation process for the preparation of alcohols and diols utilizing gas and liquid phases
04/09/1995CA2133708A1 Method of preparing a heterocyclic intermediate for the production of optically active aryloxy-substituted vicinal aminoalcohols
04/06/1995WO1995009169A1 Process for the preparation of 9-amino camptothecin
04/05/1995EP0646585A1 Adducts of bis (cyclic vinyl ethers) with carboxylic acids and their use in enantioselective synthesis
03/1995
03/28/1995CA2029785C Glutaric acid derivatives and preparations thereof
03/23/1995WO1995007905A1 Optically active imidazolidinone derivative and process for producing the same
03/22/1995CN1100410A Process for the preparation of an optically pure aminoalcohol
03/15/1995EP0643065A1 Novel bisphosphines for asymetric hydrogenation catalysts
03/15/1995EP0643052A2 Process for enantioselective hydrogenation of 2H-Pyran-2-one derivatives
03/08/1995EP0641330A1 Gaba and l-glutamic acid analogs for antiseizure treatment
03/08/1995EP0641304A1 Stereo-selective synthesis of 2-aryl-propionic acids of high optical purity by using chiral oxazolines
03/07/1995US5395986 Process for the production of cyclohexanedimethanol
03/07/1995US5395977 Process for producing optical active 4-hydroxy-2-cyclopentenone
03/07/1995US5395941 Optically active 1,4-hydropyridine compounds
03/02/1995DE4328761A1 Optically active 1-fluoroalkylbenzenes, and process for their preparation
03/01/1995EP0640089A1 Enantioselective oxazaborolidine catalysts.
02/1995
02/21/1995US5391735 Process for the preparation of 3-substituted derivatives of 1-amino-2-hydroxy-propane
02/08/1995CN1098415A Novel compounds and process
02/01/1995EP0636611A2 Optically active 1,4-dihydropyridine derivatives and process for preparing the same
02/01/1995EP0636603A1 Process for producing R-aminicarnitine and S-aminocarnitine
01/1995
01/31/1995US5386061 Chiral phospholanes via chiral 1, 4-diol cyclic sulfates
01/26/1995WO1995002585A1 Enanthioselective preparation of thiazole derivatives
01/26/1995WO1995002567A1 Catalytic asymmetric reduction of trisubstituted olefins and enamines
01/26/1995CA2167287A1 Enantioselective process for thiazole intermediates
01/17/1995US5382729 Diphosphines containing silane groups, immobilized diphosphins and the use thereof as hydrogenation catalysts
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