Patents for C07B 53 - Asymmetric syntheses (6,231)
01/2002
01/10/2002US20020004602 Asymmetric cycloaddition reactions
01/10/2002DE10030638A1 Verfahren zur selektiven Herstellung racemischer Metallocenkomplexe A process for the selective preparation of racemic metallocene complexes
01/09/2002EP1169291A1 METHODS FOR PRODUCING $g(a)-ACYLOXY CARBONYL COMPOUNDS FROM ENOL ESTER EPOXIDES
01/09/2002CN1330074A Transition metal complex, preparation method and use thereof
01/08/2002US6337406 Asymmetric catalysis based on chiral phospholanes and hydroxyl phospholanes
01/03/2002WO2002000672A1 Method for the selective production of racemic metallocene complexes
01/03/2002WO2002000668A1 Ligands and asymmetric catalysts made by using the same
01/03/2002WO2002000584A1 Cyclic ketones, their preparation and their use in the synthesis of amino acids
01/03/2002US20020002190 Antidiabetic agents increasing the expression of glucokinase (GK) to improve glucose tolerance; increase in glucose exposure coupled through GK in beta-cells to increase insulin secretion and in hepatocytes to increase glycogen deposition
01/03/2002CA2411808A1 Cyclic ketones, their preparation and their use in the synthesis of amino acids
01/02/2002EP1167373A1 Ferrocenyldiphosphine-ruthenium complexes and a hydrogenation process of exocyclic double bond of d-thiophene to d-thiophane
01/02/2002EP1166870A2 Poly-beta-amino acids, their preparation and use
01/02/2002EP1165479A1 Preparation of carvone
01/02/2002EP1165468A1 Method for carrying out the transition metal-catalyzed dimerization or codimerization of alkenes in compressed carbon dioxide which serves as a solvent
01/02/2002EP0938488B1 Phosphine ligands
01/02/2002EP0929560B1 Chiral ferrocenyls
01/01/2002US6335469 High purity (1R,2S,4R)-(-)-2-[(2′-{N,N-dimethylamino}-ethoxy)]-2-[phenyl]-1,7,7-tri-[methyl]-bicyclo[2.2.1]heptane and pharmaceutically acceptable acid addition salts thereof
01/01/2002US6335444 Amino alcohol derivative and method for preparing the same
12/2001
12/27/2001US20010056210 Hydrogenation catalyst
12/25/2001US6333291 Useful as a ligand of catalysts for asymmetric synthesis reactions such as asymmetric hydrogenation reaction
12/20/2001WO2001096279A1 Shortened synthesis of 3,3-diarylpropylamine derivatives
12/20/2001DE10029601A1 Soluble optically active polymer-enlarged catalysts comprise transition metal N,N'-bis(o-hydroxybenzylidene)-1,3-propanediamine complexes
12/19/2001EP1163207A1 An improved process for the preparation of non-hygroscopic salts of l(-)-carnitine
12/19/2001EP1163206A1 Method for hydrolyzing optically active amides
12/19/2001CN1326916A (+)-and(-)-2-cyclic dodecyl propanol and (+)-and(-)-2-cyclic dodecyl propionic acid and its preparing method and use
12/13/2001WO2001094359A1 Chiral ligands for asymmetric catalysis
12/13/2001WO2001094357A1 Antitumoral compounds
12/13/2001WO2001094278A1 Chiral monophosphites as ligands for asymetrical synthesis
12/13/2001US20010051750 Making a 2-fluoro-2-chlorocyclopropanecarboxylic acid derivative stereoselectively in high yield by reacting a diazoacetic acid derivative with 1-fluoro-1-chloroethylene using metal catalyst having chiral ligands
12/13/2001US20010051737 Catalyst for asymmetric epoxidation of enones and process for producing optically active epoxide employing it
12/13/2001DE10027505A1 Asymmetric hydrogenation, hydrosilylation, hydroboration, hydroformylation and hydrocyanation of prochiral olefins, ketones and ketimines uses transition metal catalysts containing chiral monophosphite as ligand
12/13/2001CA2410410A1 Chiral ligands for asymmetric catalysis
12/13/2001CA2410409A1 Antitumoral compounds
12/12/2001EP1162191A2 (1S,6R)- And/or (1R,6S)-2,2,6-trimethylcyclohexyl methyl ketone, process for producing the same, and perfume composition containing the same
12/12/2001EP0927152B1 Method for preparing optically active alpha-substituted benzylalcohols
12/12/2001EP0858992B1 Process for producing halogenated cyclopropane derivatives
12/12/2001EP0778827B1 Process for producing a beta-amino alcohol
12/12/2001CN1326454A Enantioselective alkylation of tricyclic compounds
12/12/2001CN1326435A Industrial process for production of L-carnitine
12/11/2001US6329536 Reacting unsaturated nitroolefin compound with beta-dicarbonyl compound in the presence of a catalyst complex and a base, catalyst complex comprising a ligand and a metal complex
12/05/2001EP1159278A2 Inhibitors of aspartyl protease
12/05/2001EP1159265A1 C-16 unsaturated fp-selective prostaglandins analogs
12/05/2001EP1159260A1 Novel compounds and compositions as protease inhibitors
12/05/2001CN1325377A New esters derived from substituted phenyl-cyclohexyl compounds
12/04/2001US6326512 Hydrogenation a b-ketosulfonic acid compound
12/04/2001US6326377 Psychological disorders therapy
12/04/2001US6326327 Process for preparing MeO-Peg-protected dihydroquinine or dihydroquinidine derivatives, new dihydroquinine or dihydroquinidine derivatives and their use
11/2001
11/29/2001WO2001090396A1 Process for the preparation of enantiomerically enriched esters and alcohols
11/29/2001WO2001090107A1 Ammonium compounds bearing an electrophilic fluorine, reagent containing same, method using same and synthesis method for obtaining them
11/29/2001WO2001090106A2 Tryasolyl tropane derivatives as ccr5 modulators
11/29/2001WO2001090056A1 Sulfonamide derivatives
11/29/2001WO2001090055A2 A process for preparing biphenyl compounds
11/29/2001WO2001090048A1 Preparation of enantiomerically enriched amine-functionalized compounds
11/29/2001WO2001089690A1 Novel chiral salen catalysts, and a process for preparing chiral compounds from racemic epoxides for using them
11/29/2001US20010047116 Increasing enantioselectivity in reductions with borane reagents
11/29/2001US20010047113 Chiral bidentate phosphine ligands with cyclic rings to restrict conformational flexibility of the ligands to enhance efficiency; stereoselective hydrogenation of ketones to alcohols, and a-acetoamidocinnamic acid to acylamino acids
11/29/2001US20010047110 Alkaline hydrogen peroxide to oxidize 2-cyano-2'-diaryl phosphinyl-1,1'-binaphthyl to obtain a 2-amido derivative, reacted with a metal alkoxide and bromine in an alcohol to a 2-sec-amino derivative; transition metal complex catalysts
11/29/2001CA2410529A1 Process for the preparation of enantiomerically enriched esters and alcohols
11/29/2001CA2409829A1 Sulfonamide derivatives
11/29/2001CA2409824A1 A process for preparing biphenyl compounds
11/27/2001US6323353 Complexes of transition metals with novel axial asymmetric compounds as the ligands
11/22/2001WO2001019761A3 Asymmetric 1,4-reductions of and 1,4-additions to enoates and related systems
11/22/2001US20010044546 Prepared from chiral amino alcohols; suitable for assymetric catalysis; for transfer hydrogenation of ketones and imines; enantiomorphs; purity; efficiency
11/21/2001EP1155024A1 Chiral diazaphospholidine ligands
11/21/2001EP1154987A1 Phenylalaninol derivatives
11/21/2001EP1154979A1 Microbial process for preparing pravastatin
11/21/2001EP0675898B1 Use of molecularly imprinted polymers for stereo- and/or regioselective synthesis
11/15/2001WO2001085727A1 Azabicyclic carbamates and their use as alpha-7 nicotinic acetylcholine receptor agonists
11/15/2001WO2001085706A1 Substituted phenylacetamides and their use as glucokinase activators
11/15/2001WO2001085668A1 Optically active 2-aminotetralin derivatives, the processes for the preparation thereof and the therapeutical use of pharmaceutical compositions containing them
11/15/2001DE10023256A1 (+)-und(-)-2-Cyclododecylpropanol und (+)-und(-)-2-Cyclododecylpropionsäure sowie deren Herstellung und Verwendung (+) - And (-) - 2-cyclododecylpropanol and (+) - and (-) - 2-cyclododecylpropionic as well as their preparation and use
11/14/2001EP1153911A1 (+)- and (-)-2-cyclododecylpropanol and (+)- and (-)-2-cyclododecylpropionic acid and the preparation and use of same
11/14/2001EP1153031A1 Method for preparing chiral diphosphines
11/14/2001CN1321636A Process for preparing homophenylalanin derivs
11/13/2001US6316667 Decyclization of 3-hydroxy-4-butyrolactone to alkyl 4-halogen-3-hydroxybutyrate by reaction with alcohol; cyanation, amidation, cyclization to oxazolidone; hydrolysis, methylation, quaternization
11/13/2001US6316660 Process for producing cyclohexylamino acids
11/13/2001US6316620 As ligands to transition metals which are used as catalysts in synthesizing asymmetric compounds to obtain specific enantiomers
11/08/2001WO2001007386A3 Asymmetric ligands having use as catalysts
11/08/2001US20010039354 Process for producing an optically active ruthenium-phosphine complex and process for producing an optically active alcohol by using the complex
11/07/2001EP1151987A1 Optically active fluorinated binaphthol derivative
11/07/2001EP1151980A1 Catalytic halogenation of activated methylene and methine compound
11/07/2001EP1151130A1 Coenzymes useful for the synthesis of l-carnitine
11/07/2001EP1150988A1 Phosphoramidate, and mono-, di-, and tri-phosphate esters of (1r, cis)-4-(6-amino-9h-purin-9-yl)-2-cyclopentene-1-methanol as antiviral agents
11/07/2001CN1321140A Transfer hydrogenation process
11/06/2001US6313317 Reacting ruthenium complex with ammonium salt; complexing, salt formation; hydrogenation catalysts
11/01/2001WO2001081286A1 Process for preparation of r-1-(aryloxy)propan-2-ol
11/01/2001WO2001081277A1 Increasing enantioselectivity in reductions with borane reagents
11/01/2001US20010037033 Stereoselective, efficient catalyst for synthesis of enantiomerically pure compounds; comprising compex of transition metal and aminophosphine ligand
11/01/2001US20010037026 Reacting a protected amino acid ester with a 4-substituted butyric acid derivative, cyclizing the protected intermediate, benzylating and decarboxylating the intermediate, asymmetric hydrogenation using a catalyst
11/01/2001US20010036653 Stereo-specific synthesis of shimikic acid derivatives with improved efficiency
11/01/2001CA2406215A1 Process for preparation of r-1-(aryloxy)propan-2-ol
10/2001
10/31/2001EP1149074A1 Acetylenic sulfonamide thiol tace inhibitors
10/31/2001EP1149072A1 Sulfonamide hydroxamates
10/31/2001EP1149068A1 A process for preparing (r)-4-cyano-3-hydroxybutyric acid ester
10/31/2001EP0906267B1 Method for producing optically active 1-phenylethylamines
10/31/2001CN1319596A Synthesis of 3,6-dialkyl 5,6-dihydro-4-hydroxide-2H-pyran-2-ketone
10/31/2001CN1073984C A process for the preparation of 5,6-dihydroxy-2-amino-1,2,3,4-tetrahydronapht-halene derivatives
10/30/2001US6310248 Process and intermediates
10/25/2001WO2001025215A3 Method for selectively dissociating cyclic carboxylic acid anhydrides
10/25/2001US20010034417 Polymeric diphosphine ligands for homogeneously soluble hydrogenation catalysts, process for the production thereof and use
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