Patents for C07B 53 - Asymmetric syntheses (6,231)
03/1999
03/18/1999WO1999012877A1 Enantioselective reduction of ketones with a silane agent/metal compound/chiral ligand system
03/18/1999CA2298533A1 Reduction enantioselective de cetones avec un systeme agent silanique/compose metallique/ligand chiral
03/17/1999EP0902011A1 $g(g)-OXO-HOMOPHENYLALANINE DERIVATIVES AND PROCESS FOR PRODUCING HOMOPHENYLALANINE DERIVATIVES BY REDUCING THE SAME
03/17/1999EP0901997A1 Process for producing optically active alcohol compound
03/17/1999EP0901996A1 Process for producing optically active amines
03/10/1999EP0900787A1 Process for preparing pyrrolidine derivatives
03/10/1999EP0900214A1 Process for preparation of pyrimidine derivatives
03/09/1999US5880285 Asymmetric hydrogenation of an imine derivative in the presence of an optically active complex containing a diphosphine ligand and iridium
03/03/1999EP0899259A1 Process for the preparation of cis-hexahydroisoindolines
02/1999
02/16/1999US5872273 Chiral diphosphine compound intermediate for preparing the same transition metal complex having the same diphosphine compound as ligand and asymmetric hydrogenation catalyst
02/16/1999US5872256 Cyclobutenedione derivative, process for preparing the same, and nonlinear optical element
02/10/1999EP0895990A1 Method for the preparation of 1-pyruvyl-L-proline
02/09/1999US5869704 Water-dispersible or water-soluble D-tocotrienol compounds and methods for making therefor
02/09/1999US5869657 Cyclization; hydrogenation; reacting with a dialkoxymethane
02/06/1999CA2244536A1 Process for preparing 1-pyruvyl-l-proline
02/04/1999WO1999005100A1 Ionic compounds with delocalized anionic charge, their use as components of ionic conductors or catalyst
02/04/1999DE19732805A1 Bis-chloro:phosphane production
02/03/1999EP0894087A2 Method for obtaining pure enantiomers of a pyridazinone derivative
02/03/1999CN1041936C Preparation for 2-keto-L-gulonates
01/1999
01/27/1999CN1206415A Process of making 3-phenyl-1-methylenedioxyphenyl-indane-2-carboxylic acid derivatives
01/27/1999CN1206011A Novel diphenylarsines
01/26/1999CA1340332C Process for producing optically active benzene-sulfonamide derivatives
01/12/1999US5859248 Process for the production of a β-amino alcohol
01/12/1999US5859031 Small molecule inhibitors of rotamase enzyme activity
01/07/1999EP0889049A1 Novel diarsine compounds
01/07/1999EP0889048A1 Preparation of optically active phospholanes, their metal complexes and their use in asymmetric synthesis
01/07/1999EP0888262A1 Cycloalkyl derivatives and the solid-phase synthesis of such derivatives
01/06/1999CN1204314A Process for preparing optically active carboxylic acids
01/05/1999US5856540 Asymmetric monolithiation of ferrocene compound using n-butyllithium in presence of a homochiaral tertiary amine, and reacting the chiral monolithium compound insitu with a chlorophosphine; a ligand in transitional metal complexes
01/05/1999US5856497 Asymmetric synthesis of α-cycloalkylalkyl substituted methanamines
12/1998
12/30/1998WO1998058735A1 Homogeneous oxidation catalysis using metal complexes
12/30/1998EP0887350A1 Chromene derivatives, process for their preparation and pharmaceutical compositions containing them
12/30/1998EP0662951B1 Process for the stereoselective synthesis of 3-substituted 2-thiomethyl propionic acids
12/30/1998CN1203586A Preparation of chiral 3-hydroxy-2-pyrrolidinone derivatives
12/30/1998CN1203235A New chromene compounds, process for their preparation and pharmaceutical compositions containing them
12/30/1998CA2295006A1 Homogeneous oxidation catalysis using metal complexes
12/23/1998EP0885897A1 Optically active diphosphine ligands
12/23/1998CN1202492A Optically active diphosphine ligands
12/22/1998US5852221 Optically active β-aminoalkoxyborane complex
12/09/1998CN1041088C Optically active imidazolizone derivative and medicinal composition for treating dementia
12/08/1998US5847222 Optically active diphosphine compound, method for making the compound, transition metal complex having the compound as ligand and method for making optically active substance by use of the complex
12/08/1998US5847186 Process for preparing asymmetric compound by using metal complex
12/03/1998WO1998054193A1 Chiral phosphorus-based ligands
12/03/1998CA2284506A1 Chiral phosphorus-based ligands
12/02/1998EP0880518A1 A process of making 3-phenyl-1-methylenedioxyphenyl-indane-2-carboxylic acid derivatives
11/1998
11/25/1998EP0595868B1 Process for the preparation of (s)-4-[3-(5-methyl-2-phenyl-4-oxazolyl)- 1-hydroxypropyl]bromobenzene
11/24/1998US5840964 Second order resolution of ketals
11/19/1998WO1998051676A1 Efficient enantioselective addition reaction using an organozinc reagent
11/18/1998CN1040751C Process for preparation of benzothiazepine derivs.
11/17/1998US5837877 Hydrogenating (n-benzyloxycarbonyl-)-4-amino-3-oxobutanoic alkyl ester in presence of ruthenium-phosphine complex; deblocking, cyclization, lactamization, catalysis
11/11/1998EP0877029A2 Optically active phosphine derivative having vinyl group, polymer produced using the same as monomer and transition metal complexes of these
11/04/1998EP0875498A2 Process for the production of the isomers (R) and (S)-Alpha-methyl-3-(trifluoromethyl)benzeneethanamine
11/04/1998CN1198157A Dinaphtazepinium salts useful as enantioselective epoxidation catalysts
11/03/1998CA2161969C Enantioselective oxazaborolidine catalysts
10/1998
10/29/1998CA2212203A1 Process for the production of the isomers (r) and (s)-alpha-methyl-3-(trifluoromethyl)benzeneethanamine
10/28/1998CN1197070A Process for preparing optically active phenylglycidyl acid derivative
10/27/1998US5827794 Supported highly-polar liquid phase chiral sulfonated binap catalyst for asymmetric synthesis of optically active compounds
10/27/1998CA1340105C Process for the preparation of optically active 3-demethylmevalonic acidderivatives and intermediates
10/22/1998WO1998046578A1 THE PREPARATION OF ENANTIOMERICALLY ENRICHED OXAZOLONES AND α,α-DISUBSTITUTED AMINO ACIDS
10/22/1998CA2284591A1 The preparation of enantiomerically enriched oxazolones and .alpha.,.alpha.-disubstituted amino acids
10/21/1998EP0871621A1 Asymmetric synthesis catalyzed by transition metal complexes with new chiral ligands
10/21/1998CN1040319C (1)-Ritodrine
10/14/1998CN1196046A Separation of optically active amides
09/1998
09/22/1998US5811552 Cyclobutenedione derivative, process for preparing the same, and nonlinear optical element
09/17/1998DE19711999A1 New 2-alkyl:sulphonyl-propane:sulphonate salts
09/16/1998EP0864586A2 Chiral compounds, synthesis and use on a support
09/16/1998EP0864576A1 Novel amidophospine-phosphinite derivatives
09/16/1998EP0863872A1 Preparation of chiral 3-hydroxy-2-pyrrolidinone derivatives
09/16/1998CN1193020A Amidophosphinephosphinite compounds
09/15/1998US5808162 Chiral unsymmetric diphosphine compound and transition metal complex containing the same as ligand
09/15/1998US5808156 Process for the production of the isomers (R) and (S)-α-methyl-3(trifluoromethyl)benzeneethanamine
09/15/1998US5808112 Chemical intermediate for immunosuppressants and prostaglandins
09/15/1998US5808098 Reducing agent from aminoalcohol
09/11/1998WO1998039345A1 6,6'-bis-(1-phosphanorbornadiene) diphosphines
09/11/1998WO1998039276A1 Process for producing optically active amines
09/09/1998EP0863125A1 Process for the preparation of enantiomerically pure diesters of 3-hydroxyoctandioic acid by asymmetric catalytic hydrogenation
09/09/1998EP0862549A1 Process for preparing optically active carboxylic acids
09/09/1998EP0674618B1 Asymmetric process for preparing florfenicol, thiamphenicol, chloramphenicol and oxazoline intermediates
09/01/1998US5801280 Processes for preparing optically active alcohols and optically active amines
09/01/1998US5801261 Bisphosphines as catalysts for asymmetric reactions
09/01/1998US5801249 Chiral auxiliaries
08/1998
08/26/1998EP0860439A1 Process for preparing an optically active phenylglycidyl acid derivative
08/21/1998CA2228196A1 Process for preparing an optically active phenylglycidyl acid derivative
08/20/1998WO1998035934A1 η-OXO-HOMOPHENYLALANINE DERIVATIVES AND PROCESS FOR PRODUCING HOMOPHENYLALANINE DERIVATIVES BY REDUCING THE SAME
08/19/1998EP0858992A1 Process for producing halogenated cyclopropane derivatives
08/19/1998EP0680484B1 Optically active beta-aminoalkoxyborane complexes
08/18/1998US5795908 Fkbp immunophilins for enzyme inhibitors
08/18/1998CA2077541C Chiral catalysts and epoxidation reactions catalyzed thereby
08/11/1998US5792770 Administering as sedative, tranquilizer, anxiolytic agent
08/05/1998EP0855935A1 Chiral solid catalyst, its preparation and its use for the production of substantially enantiomerically pure products
08/04/1998US5789609 Catalyst for assymetric synthesis, reaction of an a-cyano ester and a vinyl ketone to produce an oxo cyano ester
07/1998
07/29/1998EP0751927A4 Synthesis of compounds with predetermined chirality
07/28/1998US5786485 Optically active beta-aminoalkoxyborane complex
07/28/1998US5786484 Racemization and asymmetric transformation processes used in the manufacture of levobupivacaine and analogues thereof
07/21/1998US5783738 Optically active diphosphines, preparation thereof according to a process for the resolution of the racemic mixture and use thereof
07/21/1998US5783715 Silylated ferrocenyldiphosphines, silylated ferrocenyldiphosphines bound to inorganic or polymeric organic supports and also metal complexes thereof, their preparation and uses
07/16/1998WO1998030569A1 Asymmetric synthesis and catalysis with chiral heterocyclic compounds
07/16/1998WO1998030543A1 Endothelin intermediates by asymmetric conjugate addition reaction using a chiral additive
07/16/1998CA2277161A1 Endothelin intermediates by asymmetric conjugate addition reaction using a chiral additive
07/14/1998US5780692 Catalytic asymmetric hydrogenation of a benzophenone; simplification
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