Patents for C07B 53 - Asymmetric syntheses (6,231)
10/1992
10/20/1992US5157129 Enantiospecific synthesis of s-(+)-5,6-dihydro-4-(r-amino)-4h-thieno(2,3-b)thiopyran-2-sulfonamide-7,7-dioxide
10/14/1992EP0508307A2 Optically active secondary amine compound; process for producing optically active secondary amine compound and process for producing optically active carboxylic acid by using said compound
10/14/1992CN1065264A Stereoselective preparation of substituted piperidines
09/1992
09/27/1992WO1992017449A1 Stereoselective preparation of substituted piperidines
09/19/1992WO1992016197A1 Composition and method containing optically pure (s) metoprolol
09/19/1992CA2106494A1 Composition and method containing optically pure (s) metoprolol
09/08/1992US5145998 Method for producing optically active amines
09/01/1992US5144042 Process for preparing optically active 3-hydroxypyrrolidine derivatives
08/1992
08/25/1992US5142099 Enantioselective process
08/25/1992US5142066 Stereoselective process for the preparation of 2-amino-ethanol derivatives having a central analgesic activity and intermidiates thereof
08/25/1992US5142063 For hydrogenation of alpha-beta unsaturated acids and esters alpha-meto lactones and alpha-keto acids or esters
08/11/1992US5138037 Process for preparing peptide synthons
07/1992
07/29/1992EP0496700A1 Diphosphines containing silane groups, immobilized diphosphines and their use as hydrogenation catalysts
07/22/1992CN1017527B Process for preparing optically active oxo-isoindolinyl derivatives
07/21/1992US5132464 Hydrogenation process
07/21/1992US5132433 Process for the preparation of clausenamide and neoclausenamide, and derivatives thereof
07/21/1992US5132428 Process for preparing enantiomerically pure alpha-amino acids
07/14/1992CA1305153C Optically active styrene derivatives, polymers obtained from these, complexes with iridium(i) and their use
07/07/1992US5128488 Phosphorus-metal complex catalyst
07/07/1992US5128478 Oxazoline-carboxylic acid derivatives and method for the preparation thereof
07/01/1992EP0492719A1 Method for the preparation of erythro vicinal amino-alcohols
07/01/1992EP0492401A1 Asymmetric hydrogenation
07/01/1992EP0491887A1 Cyclic chiral compounds
06/1992
06/30/1992CA1304373C Process for the preparation of optically active secondary amines
06/25/1992CA2058111A1 Method for the preparation of erythro vicinal amino-alcohols
06/22/1992CA2058112A1 Asymmetrical hydrogenation
06/20/1992WO1992011236A1 Aerosol formulations
06/20/1992CA2098298A1 Aerosol formulations
06/11/1992WO1992009545A2 New methods for the catalytic reduction of organic substrates
06/11/1992CA2096747A1 New methods for the catalytic reduction of organic substrates
06/02/1992US5118836 Optically active fluorine-containing 3-hydroxybutyric acid esters and process for producing the same
05/1992
05/20/1992EP0485894A1 Semi-synthetic diastereomerically pure N-glycidyl-anthracyclines, methods for their preparation, and their use as cytostatics
05/19/1992CA1301176C Process for the preparation of optically active secondary arylamines
05/15/1992CA2055334A1 Semisynthetic diastereomerically pure n-glycidylanthracyclines, a process for the steroselective preparation thereof and the use thereof as cytostatics
05/13/1992EP0485069A1 Process for producing optically active amines
05/12/1992US5112999 With diphosphines and diphosphinites, catalysts for hydrogenation of imines to secondary amines
05/06/1992EP0484271A1 Process for the preparation of optically active aliphatic hydroxycarboxylic acid esters
05/03/1992CA2051466A1 Process for the preparation of optically active aliphatic hydroxycarboxylic acids
04/1992
04/15/1992CN1060290A Asymmetric epoxidation using chiral hydroperoxide
04/14/1992CA1298846C Process for the asymetrical hydrogenation of carbonyl compounds and compounds thus obtained
04/14/1992CA1298843C Camphor derivatives, their preparation and their use
04/08/1992EP0479542A1 A phosphino binaphthyl compound and transition metal complexes thereof
04/08/1992EP0479541A1 Iridium-optically active phosphine complex and catalytic production of optically active alcohols therewith
04/01/1992EP0478147A1 Process for producing optically active gamma-butyrolactone derivatives
04/01/1992EP0478063A1 Method of making optically active alcohols
04/01/1992EP0478062A1 In-situ preparation of diisopinocampheyl chloroborane
03/1992
03/25/1992CA2050825A1 Method of making optically active alcohols
03/25/1992CA2050820A1 In-situ preparation of diisopinocamphenyl chloroborane
03/24/1992US5099077 Chiral phosphorus compounds, a process for their manufacture and their application to the catalysis of enantioselective synthesis reactions
03/24/1992US5099067 Use of ammonium formate as a hydrogen transfer reagent for reduction of chiral nitro compounds with retention of configuration
03/17/1992US5097064 By reduction of arylacrylic acid using a rhodium derivative and water soluble chiral ligand as catalyst
03/10/1992US5095114 Trialkylchlorosilane, (de)cyclization
03/04/1992EP0472790A1 Asymmetric epoxidation using a chiral hydroperoxide
02/1992
02/23/1992CA2023600A1 Asymmetric epoxidation using a chiral hydroperoxide
02/12/1992EP0470756A2 Ruthenium-phosphine complex useful as catalyst and intermediate for synthesis thereof
02/11/1992US5087732 Glutaric acid derivatives and preparation thereof
02/11/1992US5087728 Process for producing carboxylic acids and esters thereof
02/05/1992CN1015361B Enantiomeric glutaramide diuretic agents
01/1992
01/28/1992US5084569 Trioxy bicyclic compounds useful for preparing optically active carboxylic acids
01/21/1992CA1294736C Renin inhibitors containing 5-amino-2,5-disubstituted- 4-hydroxypentanoic acid residues
01/15/1992EP0466405A1 2,2'-Bis(dicyclopenthylphosphino)-1-1'-binaphthyl and metal complexes thereof
01/08/1992EP0464439A2 Process for the preparation of secondary or tertiary alcohols
12/1991
12/31/1991CA1293734C Process for preparing optically active cyano compound
12/25/1991CN1015178B Process and intermediates for beta-lactam antibiotics
12/17/1991US5073648 Intermediates for dopamine derivatives
12/11/1991CN1056876A Preparation of substituted piperidines
12/08/1991WO1991018910A1 Cyclic chiral compounds
12/08/1991CA2064234A1 Cyclic chiral compounds
12/01/1991WO1991018878A1 Preparation of substituted piperidines
11/1991
11/26/1991US5068433 Antidepressants
11/26/1991US5068369 Enantiomorphs
11/21/1991EP0457469A1 Chiral auxiliaries and their use in the synthesis of chiral molecules
11/21/1991EP0456960A1 Optically active salts of a substituted thiazolidine 4-carboxylic acid and a 3-cyano-2-hydroxypropyl-trimethylammonium, their preparation and use
11/19/1991US5066815 Asymmetric hydrogenation of ketone, ruthenium-phosphine catalyst
11/19/1991US5066801 Preparation of sulfonic acid esters
11/06/1991CN1055930A Process for preparing optically active isomers of 6-substituted purinyl piperazine derivatives
10/1991
10/30/1991EP0454385A1 Process for preparing optically active isomers of 6-substituted purinyl piperazine derivatives
10/24/1991CA2040886A1 Process for preparing optically active isomers of 6-substituted purinyl piperazine derivatives
10/23/1991EP0453288A1 Enantiospecific synthesis of S(+)-5,6-dihydro-4-(R-amino)-4H thieno (2,3-B)thiopyran-2-sulfonamide-7,7-dioxide
10/23/1991EP0453195A1 (S)-alkyl 3-(thien-2-ylthio) butyrate and analogs and synthesis thereof
10/19/1991CA2040605A1 (s)-alkyl 3-(thien-2-ylthio)butyrate and analogs and synthesis thereof
10/19/1991CA2040604A1 Enantiospecific synthesis of s-(+)-5,6-dihydro-4-(r-amino)-4h-thieno[2,3-b] thiopyran-2-sulfonamide-7,7-dioxide
10/16/1991EP0452143A2 Process for preparing optically active 3-hydroxypyrrolidine derivatives
10/02/1991EP0449011A2 Stereoselective process for the preparation of 2-amino-ethanol derivatives having a central analgesic activity and intermediates thereof
10/01/1991US5053546 Hexamaphtho-hexaoxa (-imina,-thea)-1,8-diborabicyclo (6,6,6) eicosahexanes; ligands; adducts; catalysts
09/1991
09/30/1991WO1991014672A1 Chiral catalysts for enantioselective synthesis
09/22/1991WO1991014694A1 Chiral catalysts and epoxidation reactions catalyzed thereby
09/11/1991EP0446185A1 Alpha-amino-omega-alkylthioacylcarnitines active on the cardiovascular system and pharmaceutical compositions containing same
09/10/1991US5047557 Alcohol, amine intermediates
09/10/1991US5047407 Prevention Or Treatment Of Human Immunodeficiency Virus
09/04/1991EP0444930A1 Compounds containing 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl and catalytic metal complexes thereof
08/1991
08/28/1991EP0443606A2 4-(4-alkoxyphenyl)-2-butylamine derivatives and process therefor
08/27/1991US5043448 Acid catalyzed deprotection/cyclodehydration
08/20/1991US5041678 Cycloaliphatic ketones for use as perfuming and flavoring ingredients
08/20/1991US5041637 Process for the synthesis of optically active aminoacids
08/20/1991US5041602 Cinnamic acid used as inexpensive starting material
07/1991
07/31/1991EP0439129A2 Optically active isoxazole derivatives and intermediates for preparation thereof as well as processes for producing the same
07/23/1991WO1991010642A1 Process for preparing homochiral amines and process for preparing intermediates for the preparation thereof, and the intermediates prepared in accordance with this process
07/23/1991US5034535 Multistage reaction with chloroformate ester and isopropylamino-1,2-propanediol for cyclization, sulfonation and etherification
07/23/1991CA2074075A1 Process for preparing homochiral amines and process for preparing intermediates for the preparation thereof, and the intermediates/in accordance with this process prepared
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