Patents for C07B 53 - Asymmetric syntheses (6,231)
06/1988
06/15/1988EP0270596A1 A stereoconservative synthesis of 1-substituted (s)- and (r)-2-aminomethylpyrrolidines and intermediates thereto
06/07/1988US4749809 Optically active borane complex and a method for producing an optically active alcohol derivative by the use thereof
05/1988
05/17/1988US4745218 Process for the enantioselective production of α-vinyl-α-aminocarboxylic acids
03/1988
03/30/1988EP0261336A2 Process for the preparation of pure enantiomers of R-(+)-alpha-lipoic acid and S-(-)-alpha-lipoic acid (thioctic acid), and nonene or mesyl derivatives as intermediates therefor
03/29/1988US4734507 Optically active ketals, processes for their preparation and their use in the synthesis of alpha-arylalkanoic acids
03/22/1988US4732999 Optically-active di-[3-chloro-2-oxy-propyltrimethylammonium]-tartrate
03/22/1988US4732709 Racemic resolution
03/15/1988US4731455 Process for the preparation of gamma-butyrolactams
03/15/1988CA1234143A1 Process for preparing 2-(4-hydroxyphenoxy)alkanoic acid compounds
03/09/1988CN87105898A Process for preparing of n-(s-3-alkylenanthyl)-d-r-glutamoylaminoacetyl-d-alanine and intermediate
03/08/1988US4729985 Hypotensive agents
03/02/1988EP0257787A1 Process for producing optically active benzene-sulfonamide derivates
02/1988
02/24/1988EP0256982A2 Method for the preparation of optically active secondary aryl amines
02/09/1988CA1232613A1 ( )-4-substituted-2-indanols and insecticidal ester derivatives
02/03/1988EP0254971A1 Carboxylic acid synthesis process
01/1988
01/20/1988EP0253785A1 Efficient stereoconservative syntheses of 1-substituted (S)- and (R)-2-aminomethylpyrrolidines and intermediates therein
01/20/1988EP0253700A1 Process for the asymmetric hydrogenation of carbonyl compounds, and the compounds obtained thereby
01/07/1988EP0251994A1 Optically active styrene derivatives, polymers therefrom, complexes with iridium (I) and their use
12/1987
12/30/1987WO1987007889A1 Asymetric hydrogenation process for carbonyl compounds, and compounds obtained
12/15/1987US4713380 Production of optically pure organoboranes
12/03/1987WO1987007271A1 A stereoconservative synthesis of 1-substituted (s)- and (r)-2-aminomethylpyrrolidines and intermediates thereto
11/1987
11/19/1987EP0246195A1 Optically active iridium complexes and their use
11/19/1987EP0246194A2 Complexes of iridium and their use
10/1987
10/14/1987EP0241235A2 Process for the preparation of homoallyl alcohols
09/1987
09/29/1987US4697036 Process for the preparation of optically active alpha-arylalkanoic acids and novel intermediates thereof
09/16/1987EP0237305A2 A method for producing optically active amines
09/16/1987EP0236566A2 Stereoselective process for preparing optically active alpha, beta-disubstituted carbonyl compounds
09/08/1987US4692543 Optically-active di-[3-chloro-2-oxy-propyltrimethylammonium]-tartrate
09/01/1987US4691020 Ketenes, optically active alcohols, tertiary amines, deesterification
07/1987
07/28/1987CA1224805A1 PROCESS FOR THE ENANTIOSELECTIVE PRODUCTION OF .alpha.- ALKYLATED; ACYCLIC .alpha.-AMINOCARBON ACIDS
06/1987
06/03/1987CN86106592A Process for preparation of gamma-butyrolactams
06/02/1987US4670192 Optically-active di-[3-chloro-2-oxy-propyltrimethylammonium]-tartrate
05/1987
05/20/1987EP0222163A1 Process for the manufacture of gamma-butyrolactames
05/12/1987US4665212 Condensation of hydroquinone with carboxyalkyl sulfonate
05/12/1987US4665171 Carbacephalosporins
05/06/1987EP0220417A1 Process for the enantioselective preparation of alpha-vinyl-alpha-aminocarboxylic acids
04/1987
04/22/1987EP0218970A2 Chiral rhodium-diphosphine complexes for asymmetrical hydrogenation
04/22/1987CN86106525A Phosphorus compounds
04/08/1987EP0217376A2 Process for preparing optically active alpha-haloalkyl-arylketones
04/08/1987EP0217375A2 Process for preparing optically active carbonyl compounds
03/1987
03/31/1987US4654176 Sulphonated chiral phosphines, their preparation and their use
03/24/1987US4652657 Chiral rhodium-diphosphine complexes
03/11/1987CN86105870A Blood vessel tension peptide protoenzyme inhibitor with 5-amino-2.5-disubstituted-4-hydroxy pentacarboxyl
03/04/1987EP0212903A2 Polypeptide derivatives containing 5-amino-2,5-disubstituted-4-hydroxypentanoic acid residues
02/1987
02/04/1987EP0210896A1 Optically pure derivates of 4-amino-3-hydroxycarboxylic acids and process for stereospecific synthesis
02/04/1987EP0210589A2 Process for preparing optically active alpha-halogen ketals
02/04/1987CN86104783A Process and intermediates for b-lactam antibiotics
01/1987
01/28/1987EP0209636A1 Process for the preparation of a chiral aromatic cyanohydrin
01/21/1987EP0209352A2 Process and intermediates for beta-lactam antibiotics
12/1986
12/30/1986EP0206993A1 Sulphonic-acid esters
12/30/1986EP0205782A1 Chiral cyanohydrination process
12/24/1986CN85103245A Production of chiral rhodium-diphosphine complexes and use in asymmetric hydrogenations
12/09/1986US4628120 Rearrangements using organoaluminum compounds
11/1986
11/25/1986US4625053 From 2-halopropionate, hydroquinone or salt, alkali hydroxide
10/1986
10/29/1986EP0102520B1 Process for the inversion of the configuration of optically active compounds, and optically active intermediates for this process
10/22/1986EP0198348A2 Process for preparing (+)S-2-hydroxy-2-methyl-hexanoic acid
09/1986
09/24/1986CN85101426A Process for optically active di-(3-chloro-2-oxypropyl trimethyl ammoniuml tartrate
09/09/1986US4611077 Increasing enantiomeric selectivity in chiral cyanohydrination
09/09/1986US4611076 Chiral cyanohydrination process
09/03/1986EP0192849A1 Process for preparing optically active 2-(4-hydroxyphenoxy)propionic acid compounds
08/1986
08/14/1986WO1986004578A1 Method for producing l-phenylalanine
08/12/1986US4605750 Catalysts
08/05/1986US4604486 Pinacol-type rearrangement of solfonyloxy alcohols in presence fo organoaluminum compounds
07/1986
07/29/1986US4603218 Alkyl diazoacetate
07/23/1986EP0188235A2 Production of optically pure organoboranes
07/08/1986US4599444 Process for the separation of isomeric cyclopropane-carboxylic acids
05/1986
05/07/1986EP0180126A2 Process for preparing 2-(4-hydroxyphenoxy)alkanoic acid compounds
05/06/1986US4587357 Preparation of enantiomers of a substituted fluorenyloxyacetic acid
04/1986
04/29/1986US4585892 Process for the enantioselective production of α-alkylated, acyclic α-aminocarboxylic acids
04/15/1986US4582930 Process for the preparation of optically active alpha-arylalkanoic acids
04/09/1986EP0176947A1 Preparation of enantiomers of a substituted fluorenyloxyacetic acid
04/01/1986US4579968 Rearranging aryl retals and hydrolysis of esters obtained to acids; adrotic dipolar dilvents
02/1986
02/26/1986EP0172614A1 Process for producing optically active carboxylic acid amides
02/19/1986EP0171832A2 Camphor derivatives, their preparation and their use
02/12/1986EP0171175A1 An optically active borane complex and a method for producing an optically active alcohol derivative by the use thereof
02/05/1986EP0170211A1 Process for preparing L-phenylalaninemethylester hydrochloride
11/1985
11/12/1985US4552972 Chiral copper complex
10/1985
10/23/1985EP0158913A2 Process for the preparation of optically active alpha-arylalkanoic acids and intermediates thereof
10/23/1985EP0158875A2 Chiral-rhodium-diphosphine complexes for asymetric hydrogenations
10/16/1985EP0158255A2 Optically active ketals, processes for their preparation and their use in the synthesis of apha-arylakanoic acids
10/09/1985EP0157315A2 Optically active di(3-chlor-2-oxypropyl-trimethyl-ammonium) tartrate
09/1985
09/18/1985EP0154853A1 Process for the preparation of optically active alpha-arylalkanoic acids
09/04/1985EP0153701A1 Process for the preparation of optically active alpha-arylalkanoic acids
09/03/1985US4539420 Optically active 1-aromatic-group-substituted-1-alkanones and methods for their manufacture
08/1985
08/14/1985EP0069761B1 (+)-4-substituted-2-indanols and insecticidal ester derivatives
07/1985
07/23/1985CA1190936A1 Borane complexes
04/1985
04/17/1985EP0137351A2 Process for the enantioselective préparation of acyclic alpha-alkylated alpha-aminecarboxylic acids
04/03/1985EP0136210A1 Chiral phosphorus ligands, process for their preparation and their use in the catalysis of enantioselective synthesis reactions
03/1985
03/27/1985EP0135392A2 Rhodium-phosphine complexes
03/19/1985CA1184178A1 Optically-active diamide derivatives
02/1985
02/13/1985EP0133127A1 Sulphonated chiral phosphines, their preparation and their use in asymmetric catalysis
01/1985
01/30/1985EP0132392A2 Asymmetric synthesis of alpha-substituted-alpha-cyanomethyl alcohols
01/29/1985CA1181766A1 Preparation of optically active carboxylic acids
01/22/1985US4495355 Optically-active diamide derivatives
12/1984
12/12/1984EP0128012A2 Novel chiral copper complex and asymmetric synthesis of cyclopropanecarboxylate derivatives using said complex as catalyst
09/1984
09/26/1984EP0119463A1 Process for the separation of isomers of substituted cyclopropanecarboxylic acids
07/1984
07/31/1984US4463176 Regeneration of separated chiral isocyanate-treated adrenergic blocking agents using hydrazine hydrate and a keto acid
03/1984
03/14/1984EP0102520A1 Process for the inversion of the configuration of optically active compounds, and optically active intermediates for this process
03/13/1984US4436919 For asymmetric hydroboration and reduction reactions
02/1984
02/21/1984CA1162542A1 Catalytic asymmetric hydrogenation
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