Patents for C07B 53 - Asymmetric syntheses (6,231)
04/1997
04/23/1997EP0769006A1 Small molecule inhibitors of rotamase enzyme activity
04/17/1997WO1997013763A1 Asymmetric synthesis catalyzed by transition metal complexes with new chiral ligands
04/16/1997CN1147813A Novel selective inhibitors of viral or bacterial neuraminidases
04/16/1997CN1147808A A process for the preparation of 5,6-dihydroxy-2-amino-1,2,3,4-tetrahydronaphthalene derivatives
04/09/1997EP0766662A1 Asymmetric synthesis of (r)- and (s)-arylethanolamines from iminoketones
04/09/1997EP0746410A4 Water-soluble chiral sulfonated binap catalyst for asymmetric synthesis of optically active compounds
04/01/1997US5616802 Cyclobutenedione derivative, process for preparing the same, and nonlinear optical element
04/01/1997US5616750 Compounds and process
04/01/1997US5616737 Stereoselective preparation of (-) 3a,6,6,9a-tetramethyl-perhydronaphtho[2,1-b]furan
03/1997
03/26/1997EP0764652A1 Novel intermediates for the synthesis of bisphosphine compounds
03/26/1997CN1146205A Preparation of arthropodicidal oxadiazines
03/25/1997US5614641 Using a phosphino-containing ruthenium complex as catalyst
03/25/1997US5614628 Antitumor
03/25/1997US5614547 Small molecule inhibitors of rotamase enzyme
03/23/1997CA2185971A1 Intermediates for the synthesis of bisphosphine compounds
03/20/1997WO1997010201A1 Separation of optically active amides
03/20/1997DE19534208A1 Spaltung von optisch aktiven Amiden Cleaving optically active amides
03/19/1997EP0763533A1 Preparation and use of the pure enantiomers of 8-chloro-6-sulfonyloxy-octanoic acid and its alkyl esters and of the pure enantiomers of 6,8-dichloro-octanoic acid and its alkyl esters
03/19/1997EP0763005A1 TETRAHYDROINDENO[1,2-d][1,3,2]OXAZABOROLES AND THEIR USE AS ENANTIOSELECTIVE CATALYSTS
03/13/1997WO1997009329A1 Azo derivatives of 5-aminosalicylic acid for treatment of inflammatory bowel disease
03/12/1997EP0761663A1 Process for preparing optically active 3-hydroxy furan compounds
03/12/1997EP0761642A2 Process for preparing 2-amino-1, 3-alkanediol or a derivative thereof, process for preparing optically active dihydrosphingosine derivatives and intermediates used in that process
03/06/1997WO1997008128A1 Process for producing halogenated cyclopropane derivatives
03/05/1997EP0760361A2 Process for the dehalogenation without racemisation of halogeno-substituted aryl-alkylamines
03/05/1997EP0759917A1 Novel selective inhibitors of viral or bacterial neuraminidases
03/05/1997EP0759915A1 Asymmetric synthesis of chiral secondary alcohols
03/05/1997CN1144522A Substituted azetidinone compounds useful as hypocholesterolemic agents
03/04/1997US5608119 (2S)-3-[(1R, 2S, 5R)-[5-methyl-2-(1-methylethyl)-cyclohexyl]oxy]-1, 2-propanediol, process for producing the same, and compositions containing the same
02/1997
02/26/1997EP0759425A2 Process for the preparation of optically active 1-aryl-alkylamines
02/26/1997EP0759424A1 Process for producing optically active 2-hydroxy-4-arylbutyric acid or its ester, and intermediate therefor
02/26/1997EP0698028B1 Enantioselective oxazaborolidine catalysts
02/20/1997WO1997006147A1 Dinaphtazepinium salts useful as enantioselective epoxidation catalysts
02/20/1997CA2228902A1 Dinaphtazepinium salts useful as enantioselective epoxidation catalysts
02/18/1997CA2111445C Process for the preparation of intermediates in the synthesis of chiral thiazolidine-2,4-dione derivatives
02/12/1997EP0757677A1 Benzocycloalkylazolethione derivatives
02/12/1997EP0603414B1 (-)-ritodrine
02/11/1997US5602108 Antitumor agents
02/05/1997EP0756594A1 Preparation of arthropodicidal oxadiazines
02/04/1997US5600047 Process for producing optically active olefin
02/04/1997US5600015 Assymetric hydrogenation of isoprene derivatives
01/1997
01/22/1997EP0754696A1 Chiral unsymmetric diphosphine compounds and transition metal complexes containing them as ligands
01/22/1997EP0648201B1 Enantioselective hydrogenation of the carbonyl bond using ruthenium complexes with biphosphine ligands
01/21/1997US5596114 Enantioselective hydrogenation catalysts
01/08/1997EP0752423A1 Process for the stereoselective preparation of (-)3a,6,6,9a-tetramethyl-perhydronaphtho(2,1-b)furan
01/08/1997EP0751934A1 Substituted azetidinone compounds useful as hypocholesterolemic agents
01/08/1997EP0751927A1 Synthesis of compounds with predetermined chirality
01/07/1997US5591854 Enantioselective synthesis of seven-membered carbocycles and tropanes
01/02/1997EP0751141A1 Optically active monophosphino carboxylic acid derivative
12/1996
12/27/1996EP0749973A1 Novel bisphosphines as catalysts for asymmetric reactions
12/27/1996EP0749406A1 Process for the preparation of optically active cycloolefins
12/27/1996EP0640089B1 Enantioselective oxazaborolidine catalysts
12/25/1996CN1033640C 2-substituted-5-substituted-1, 3-oxathiolanes with antiviral properties
12/19/1996WO1996040633A1 Small molecule inhibitors of rotamase enzyme activity
12/18/1996EP0748326A1 Optically active diphosphines and method for preparing same by resolution of the racemic mixture
12/17/1996US5585500 Chemical reduction of a pyrrolidinedione using activated alkali boron hydride
12/11/1996EP0746551A1 Optically pure 4-aryl-2-hydroxytetronic acids
12/11/1996EP0746410A1 Water-soluble chiral sulfonated binap catalyst for asymmetric synthesis of optically active compounds
12/03/1996US5581007 Process for preparing optically active allophenylnorstatin derivatives
11/1996
11/28/1996WO1996037457A1 Asymmetric synthesis of (-) 6-chloro-4-cyclopropyl-ethynyl-4-trifluoromethyl-1,4-dihydro-2h-3,1-benzoxazin-2-one
11/27/1996EP0744401A2 Process of preparation of optically active 2-piperazine carboxylic acid
11/20/1996CN1033326C Process for preparing optically active isomers of 6-substituted purinyl piperazine derivatives
11/19/1996CA2106200C Stereoselective preparation of substituted piperidines
11/19/1996CA2080249C Preparation of substituted piperidines
11/13/1996EP0624152B1 Process for preparing ketone enantiomer
11/12/1996US5574182 Optically active compounds having plural chiral centers and production thereof
11/07/1996WO1996034842A1 Separation of alpha-arylpropionic acid ester diastereomers by distillation
11/06/1996CN1135216A Optically active imidazolidinone derivative and process for prodn. of same
10/1996
10/24/1996WO1996033183A1 Asymmetric epoxides, their synthesis and use
10/24/1996CA2216866A1 Asymmetric epoxides, their synthesis and use
10/23/1996EP0655950B1 Chiral catalysts and epoxidation reactions catalyzed thereby
10/23/1996EP0532515B1 Preparation of substituted piperidines
10/22/1996US5567841 α-phosphonosulfonate squalene synthetase inhibitors and method
10/17/1996WO1996032400A1 Dihalogenated ferrocenes and processes for the preparation thereof
10/15/1996US5565593 Chiral phospholanes via chiral 1,4-diol cyclic sulfates
10/09/1996EP0736509A2 Processes for preparing optically active alcohols and optically active amines
10/09/1996EP0736031A1 Improvements in or relating to chiral syntheses
10/09/1996EP0736017A1 Improvements in or relating to chiral auxiliaries
10/09/1996CN1132742A Method of preparing D-amino acid-N-(S)-alpha-alkylbenzylamide
10/08/1996US5563309 Ferrocenyl diphosphines as ligands for homogeneous catalysts
10/08/1996US5563295 Process for producing optically active carboxylic acid
10/08/1996US5563290 Hydrogenating an itaconic acid compound in presence of rhodium compound and a 2,2?-bis(hydrocarbon residue-substituted) phosphine substituted alkyl)-1,1?-biferrocene compound
10/03/1996WO1996030320A1 Preparation of cis-4-o-protected-2-cyclopentenol derivatives
09/1996
09/26/1996WO1996029295A1 Process for preparing asymmetric compound by using metal complex
09/24/1996US5559267 Hydrogenation process using catalysts made from chiral phospholanes via chiral 1,4-diol cyclic sulfates
09/19/1996WO1996028402A1 Stereoselective ring opening reactions
09/18/1996EP0732337A1 Optically active asymmetric diphosphine and process for producing optically active substance in its presence
09/10/1996US5554791 Reaction of aspartic acid and 1,2-dihaloethane
09/10/1996US5554788 Process for the stereoselective synthesis of 3-substituted 2-thiomethylpropionic acids
09/06/1996WO1996026933A1 Novel selective inhibitors of viral or bacterial neuraminidases
09/04/1996EP0729969A1 Silated ferrocene-diphosphine ligands, inorganic or polymeric organic support to which these ligands are bound and metal complexes thereof, and their preparation and use
09/04/1996EP0729941A1 Process for producing keto nitrile derivative and hexenone derivative
09/04/1996EP0729939A2 Process for preparing optically active allophenylnorstatin derivatives, and intermediates for use therein
09/03/1996US5552548 Enantioselective oxazaborolidine catalysts
08/1996
08/27/1996US5550291 Process for key intermediates for HIV protease inhibitors
08/27/1996US5550285 Method for producing calcium salts of [S,S]-ethylenediamine-N,N'-disuccinic acid
08/25/1996CA2170099A1 Silylated ferrocenyldiphosphines, silylated ferrocenyldiphosphines bound to inorganic or polymeric organic supports and also metal complexes thereof, their preparation and use
08/22/1996WO1996025420A1 Chiral organometallic compounds
08/14/1996EP0641333B1 Method for making intermediates useful in synthesis of retroviral protease inhibitors
08/13/1996US5545758 Process for the preparation of diisopinocampheylchloroborane
08/07/1996EP0724552A1 Process for preparing a chiral tetralone
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