Patents for C07B 53 - Asymmetric syntheses (6,231)
07/2000
07/18/2000US6090969 Process for the preparation of an asymmetric compound using a metal complex
07/18/2000US6090837 Substituted hydrochromenopyrroles
07/13/2000WO2000040552A1 Amidomalonamides and their use as inhibitors of matrix metalloproteinase
07/13/2000WO2000040548A1 Arylalkanoyl derivatives, processes for their preparation, their use and pharmaceutical compositions containing them
07/13/2000WO2000040547A1 α-SUBSTITUTION OF UNPROTECTED β-AMINO ESTER COMPOUNDS
07/13/2000WO2000040545A1 Novel method for preparing chiral amino acids
07/13/2000WO2000040529A1 Colchinol derivatives as vascular damaging agents
07/13/2000CA2358116A1 Novel method for preparing chiral amino acids_
07/13/2000CA2356966A1 Amidomalonamides and their use as inhibitors of matrix metalloproteinase
07/13/2000CA2355302A1 Colchinol derivatives as vascular damaging agents
07/12/2000EP1017650A1 Asymmetric hydrogenation
07/12/2000EP0719772B1 Optically active imidazolidinone derivative and process for producing the same
07/11/2000US6087526 Process for producing optically active 2-hydroxy-4-arylbutyric acid or its ester
07/06/2000WO2000039324A2 Method for producing optically active 1-amino-4-(hydroxymethyl)-cyclopent-2-ene derivatives
07/06/2000WO2000039068A1 Method for producing glyoxylic acid esters or the hydrates thereof
07/06/2000WO2000021910A3 1,2-disubstituted cyclopropanes
07/06/2000CA2353854A1 Process for preparing glyoxylic esters or their hydrates
07/05/2000EP1015415A1 Novel stereoselective processes for the preparation of gabapentin analogues
06/2000
06/29/2000WO2000037478A1 Ligands and complexes for enantioselective hydrogenation
06/29/2000WO2000037445A1 Alkyl esters of 3-(3,4-dihalogenophenyl)-2,6-dioxopiperidine-3-propionic acid useful as intermediates
06/29/2000WO2000037438A1 Novel thio-aminotetralin compounds useful in pain management
06/29/2000WO2000037436A1 Sulfonamide hydroxamates
06/29/2000WO2000037426A1 Novel oxo-aminotetralin compounds useful in pain management
06/29/2000DE19857302A1 Verfahren zur enantioselektiven Reduktion von 3,5-Dioxocarbonsäuren und deren Ester A process for the enantioselective reduction of 3,5-Dioxocarbonsäuren and esters thereof
06/29/2000CA2355902A1 Sulfonamide hydroxamates
06/29/2000CA2350683A1 Alkyl esters of 3-(3,4-dihalogenophenyl)-2,6-dioxopiperidine-3-propionic acid useful as intermediates
06/28/2000EP1013658A1 Aminophosphine-metal complex for asymmetric reactions
06/28/2000EP1012131A1 Enantioselective reduction of ketones with a silane agent/metal compound/chiral ligand system
06/28/2000CN1053902C Hydrogenation process
06/22/2000WO2000036134A1 Method for the enantioselective reduction of 3,5-dioxocarboxylic acids, their salts and their esters
06/22/2000WO2000010992A3 Water-dispersible or water-soluble d-tocotrienol compounds and methods for making therefor
06/21/2000DE19956374A1 Enantioselective catalytic hydrogenation of unsaturated carboxylic acid derivatives, giving chiral intermediates e.g. for biologically active compounds
06/21/2000DE19952348A1 New bisphosphinyl-ferrocene ligand components for new metal complexes useful as catalysts in asymmetric hydrogenations
06/21/2000CN1053655C Process for the preparation of an optically pure aminoalcohol
06/08/2000WO2000017228A3 Stereoselective process for enalapril
06/07/2000CN1255919A Efficient enantioselective addition reaction using organozinc reagent
06/02/2000WO2000031064A1 Enantioselective alkylation of tricyclic compounds
06/02/2000WO2000031016A1 Process for production of esters
06/02/2000WO2000031010A2 Methods for producing chiral aldehydes
06/02/2000WO2000031003A1 Process for converting an alcohol to the corresponding fluoride
06/02/2000CA2351397A1 Methods for producing chiral aldehydes
05/2000
05/31/2000EP0862549B1 Process for preparing optically active carboxylic acids
05/30/2000CA2037007C 2,2'-bis[di-(3,5-dialkylphenyl)phosphino]-1,1'-binaphthyl and transition metal complex containing the same as ligand
05/25/2000WO2000029371A1 Excitatory amino acid receptor modulators
05/25/2000WO2000029370A1 Industrial process for the production of l-carnitine
05/25/2000DE19853748A1 Production of chiral aldehyde by enantioselective hydroformylation, useful e.g. as intermediate for pharmaceuticals, uses transition metal catalyst complex containing phosphine-phosphite ligand
05/25/2000CA2350532A1 Excitatory amino acid receptor modulators
05/25/2000CA2349536A1 Industrial process for the preparation of l-carnitine
05/24/2000EP1002801A1 Chiral diphenyldiphosphines and d-8 metal complexes thereof
05/19/2000CA2290009A1 Chiral diphenyldiphosphines and d-8 metal complexes thereof
05/18/2000WO2000027855A1 Chiral ligands for asymmetric catalysis
05/18/2000WO2000027799A1 New esters derived from substituted phenyl-cyclohexyl compounds
05/18/2000WO2000027786A1 Stereoselective process for preparing (cyclo)alkyl phenylglycolic acids
05/18/2000WO1999056699A3 Main-group metal-based asymmetric catalysts and applications thereof
05/18/2000CA2349245A1 New esters derived from substituted phenyl-cyclohexyl compounds
05/18/2000CA2349209A1 Stereoselective process for preparing (cyclo)alkyl phenylglycolic acids
05/18/2000CA2347146A1 Chiral ligands for asymmetric catalysis
05/17/2000EP1000927A2 Excitatory amino acid receptor modulators
05/16/2000US6063955 Method for producing optically active erythro-3-amino-2-hydroxybutyric esters and acids thereof
05/16/2000US6063920 Simple, durable catalyst for asymmetric epoxidation of prochiral olefins
05/11/2000WO2000026220A1 Diphosphines
05/11/2000WO2000006532A3 Process for the preparation of r-(-)-carnitine
05/11/2000CA2348595A1 Diphosphines
05/04/2000WO2000024919A1 Coenzymes useful for the synthesis of l-carnitine
05/04/2000WO2000024510A1 Combinatorial approach to chiral reagents or catalysts having amine or amino alcohol ligands
05/03/2000EP0997470A1 Optically active bisphosphinomethanes and their rhodium and copper complexes for catalytic asymmetric syntheses
05/03/2000EP0820439B1 Method for the asymmetrical synthesis of s-acylated derivatives of 2-mercaptomethyl 3-phenyl propanoic acid, and use thereof for synthesising n-(mercaptoacyl) amino acid derivatives
05/03/2000EP0736031B1 Improvements in or relating to chiral syntheses
05/03/2000CN1051991C Preparation of glutaric acid derivatives
05/03/2000CN1051990C Method for preparing ring-substituted 2-amino-1,2,3,4-tetra-hydronaphthalenes
04/2000
04/29/2000CA2287713A1 Optically active bisphosphinomethanes and their rhodium and copper complexes for catalytic asymmetric syntheses
04/20/2000WO2000021910A2 1,2-disubstituted cyclopropanes
04/20/2000CA2347092A1 1,2-disubstituted cyclopropanes
04/12/2000EP0992492A1 Small molecule inhibitors of rotamase enzyme activity
04/12/2000EP0992481A1 Process for the asymmetric hydrogenation of beta-ketoesters
04/12/2000EP0991468A1 Homogeneous oxidation catalysis using metal complexes
04/12/2000EP0759917B1 Novel selective inhibitors of viral or bacterial neuraminidases
04/11/2000US6049009 Production method of optically active trans-vinylsulfide alcohol
04/06/2000WO2000018708A1 Transfer hydrogenation process
04/06/2000DE19845517A1 Verfahren zur asymmetrische Hydrierung von beta-Ketoestern A process for the asymmetric hydrogenation of beta-ketoesters
04/05/2000EP0850214B1 Separation of optically active amides
04/05/2000CN1051087C Process for preparation of diisopinocampheylchloroborane
03/2000
03/30/2000WO2000017228A2 Stereoselective process for enalapril
03/30/2000CA2343193A1 Improved stereoselective process for enalapril
03/28/2000US6043396 As ligands in metal complexes; use of metal complexes as catalyst for efficient hydrogenations (at low hydrogen pressure), hydroformylations, hydrocyanations, allylic substitutions and isomerizations of allylamines to enamines
03/28/2000US6043359 Processes for the preparation of derivatives of 4a,5,9,10,11,12-hexahydro-6H-benzofuro-[3a,3,2-ef][2]benzazepine
03/23/2000WO2000015599A1 Process for producing stereoselective nitro compounds
03/22/2000EP0987271A1 An optically active diaminophosphine ligand-transition metal complex
03/22/2000CN1050603C Prepn. of intermediate product used in process for diastereoselective synthesis of nucleosides
03/16/2000WO2000014096A1 Ferrocene-based diphosphonites for asymmetrical catalysis
03/16/2000WO2000014051A1 Esters with musky odor and their use in perfumery
03/16/2000WO2000014034A1 Microwave facilitated allyllic substitution
03/16/2000WO2000014033A1 The addition of oxygen nucleophiles to vinyl epoxides
03/16/2000CA2342238A1 Ferrocene-based diphosphonites for asymmetrical catalysis
03/15/2000EP0984972A1 Chiral phosphorus-based ligands
03/14/2000US6037505 Enantioselective oxazaborolidine catalysts
03/14/2000US6037500 Asymmetric synthesis catalyzed by transition metal complexes with cyclic chiral phosphine ligands
03/14/2000US6037498 Chiral syntheses
03/14/2000US6037493 Optically active diphosphines, preparation thereof according to a process for the resolution of the racemic mixture and use thereof
03/14/2000US6037479 Chiral diarsine compounds
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