Patents for C07B 53 - Asymmetric syntheses (6,231)
05/2002
05/23/2002US20020061815 3,5-Dioxa-8-aza-tricyclo[5.2.1.00,0]decane-9-methanols, their metal complexes and enantio-selective hydrogenation processes
05/23/2002CA2429252A1 Chiral diphosphines and their metal complexes
05/22/2002EP1206443A2 Process for preparing (-)-(1s,4r) n-protected 4-amino-2-cyclopentene-1-carboxylate esters
05/22/2002EP1206438A1 N-substituted norephedrine chiral derivatives, their preparation and their use for the synthesis of optically active functionalised compounds by hydrogen transfer
05/22/2002EP1206427A1 Chiral ligands, transition-metal complexes thereof and uses thereof in asymmetric reactions
05/22/2002CN1349971A Olfination method of itaconic acid and succinic acid derivatives
05/21/2002US6392103 Using organometallic compound as catalyst
05/16/2002WO2002038565A2 7-(r)-amino-triazolopyrimidines, the production thereof and use of the same for combating phytopathogenic fungi
05/16/2002WO2002038544A2 3-substituted oxindole beta 3 agonists
05/16/2002WO2002038543A2 3-substituted oxindole beta 3 agonists
05/16/2002WO2002038535A1 Optically active cobalt (ii) or (iii) complexes, process for the preparation thereof and intermediates therefor
05/16/2002US20020058660 For control of insect and acarid pests
05/16/2002CA2421594A1 3-substituted oxindole beta 3 agonists
05/15/2002EP1205476A1 Process for the synthesis of N-(mercaptoacyl)-amino acids derivatives from alpha-substituted acrylic acids
05/15/2002CN1084742C Process for preparing 3-phenyl-1-methylenedioxyphenyl-indame-2-carboxylic acid derivatives
05/14/2002US6388130 Method for producing axial asymmetric compounds, and intermediates for producing the same
05/14/2002US6387033 Preparation of new layered double hydroxides exchanged with osmate for asymmetric dihydroxylation of olefins to vicinal diols
05/14/2002CA2010542C Ring-substituted 2-amino-1,2,3,4-tetrahydronaphthalenes and 3-aminochromanes
05/10/2002WO2002036594A1 Process for the preparation of crystalline n-formimidoyl thienamycin monohydrate (imipenem monohydrate)
05/10/2002WO2002036261A2 Catalyst comprising a chiral cationic metal-ligand complex immobilised on a mesoporous alumino-silicate support, its preparation and use in asymmetric hydrogenation
05/10/2002WO2002018349A3 Process and intermediates for preparing retroviral protease inhibitors
05/09/2002US20020055653 Diphosphines
05/09/2002US20020055645 Process for synthesizing N-(mercaptoacyl) amino acid derivatives from alpha-substituted acrylic acids
05/08/2002EP1203616A1 Chiral lead catalyst and method of asymmetric aldol reaction
05/08/2002EP1202986A1 Amine and amide derivatives as ligands for the neuropeptide y y5 receptor useful in the treatment of obesity and other disorders
05/08/2002EP1202952A1 Method for producing amines by homogeneously catalyzed reductive amination of carbonyl compounds
05/08/2002CN1347693A Noval compound, its synthetizing process and therapeutic use
05/08/2002CN1084326C Splitting of active amide
05/07/2002US6384265 Acid catalysis for rearrangement/inversion of stereoconfiguration; kinetic resolution of racemic mixtures using a chiral catalyst
05/07/2002US6384220 Antidiabetic agents increasing the expression of glucokinase (gk) to improve glucose tolerance; increase in glucose exposure coupled through gk in beta-cells to increase insulin secretion and in hepatocytes to increase glycogen deposition
05/02/2002US20020052524 Process for preparing (-)-(1S, 4R) N-protected 4-amino-2-cyclopentene-1-carboxylate esters
05/02/2002US20020052352 Treating a malignant tumor, like a melanoma, using plant-derived compounds
05/02/2002US20020052306 (+)- And (-)-2-cyclododecylpropanol and (+)- and (-)-2-cyclododecylpropionic acid and the preparation and use thereof
05/02/2002EP1201673A1 Bidentate organophosphorous ligands and their use in catalysis
05/02/2002EP1200452A1 Novel chiral phosphorus ligands and the use thereof in the production of optically active products
05/02/2002EP1200419A1 Aminothiazole derivatives and their use as crf receptor ligands
05/02/2002EP1200394A1 Process for preparing acids via alpha-chloroepoxy esters
05/02/2002EP1200390A1 Production of n-substituted 2,7-dialkyl-4-hydroxy-5-amino-8-aryl-octanoylamides
05/02/2002EP1200387A1 Process for the cis-selective catalytic hydrogenation of cyclohexylidenamines
05/02/2002EP1200386A1 Process for the preparation of naproxene nitroxyalkylesters
05/02/2002EP1200384A1 2-alkyl-5-halogen-pent-4-ene carboxylic acids and their production
05/02/2002DE10052391A1 New bidentate organophosphorus ligands with a chiral carbon center, used in complex compounds for use as catalysts in asymmetric reactions or polymerizations, especially asymmetric hydroformylation or hydrogenation
05/01/2002CN1347400A Microbial process for preparing pravastatin
04/2002
04/30/2002US6380416 Chiral bidentate phosphine ligands with cyclic rings to restrict conformational flexibility of the ligands to enhance efficiency; stereoselective hydrogenation of ketones to alcohols, and a-acetoamidocinnamic acid to acylamino acids
04/30/2002US6380412 Optically active diphosphines, preparation thereof according to a process for the resolution of the racemic mixture and use thereof
04/30/2002US6380408 Non-calcemic, antiproliferative, transcriptionally active sulfur-containing analogs of 1α, 25-dihydroxy vitamin D3
04/30/2002US6380224 For therapy of eating disorders, obesity, bulimia nervosa, diabetes, memory loss, epileptic seizures, migraine, sleep disturbances, pain, sexual/reproductive disorders, depression and anxiety
04/30/2002US6379936 With crotonobetainyl-coenzyme a and l(-)-carnitine dehydratase, adding d(+)-carnitine and isolating l-isomer
04/25/2002US20020049331 Reacting cyclopropylcarboxaldehyde with substituted phosphorylglycine to form enamide which is hydrogenated in presence of transition metal catalyst containing metal and bis-phosphine compound; chemical intermediates
04/24/2002EP1199301A1 Olefination process to itaconate and succinate derivatives
04/24/2002EP0912467B1 Asymmetric hydrogenation method of a ketonic compound and derivative
04/24/2002CN1346360A Phosphoramidate, and mono-di, and tri-phosphate esters of (1R, cis)-4-(6-amino-9H-purin-9-YL)-2-cyclopentene-1-methanol as antiviral agents
04/24/2002CN1346342A Method for hydrolyzing optically active amides
04/24/2002CN1083450C Processes for preparing intermediate product used in method of diastereoselective syntheses of nucleosides
04/23/2002US6376684 Chemical intermediate for oxybutynin-type compounds
04/18/2002WO2002030919A1 SYNTHESIS OF R(+)α-LIPOIC ACID
04/18/2002WO2002030415A1 Pravastatin sodium substantially free of pravastatin lactone and epi-pravastatin, and compositions containing same
04/18/2002WO2002030356A2 Synthesis of epothilones and relates analogs
04/18/2002WO2002010095A3 Process for the cyanation of aldehydes
04/18/2002CA2425828A1 Synthesis of epothilones and related analogs
04/18/2002CA2422744A1 Pravastatin sodium substantially free of pravastatin lactone and epi-pravastatin, and compositions containing same
04/17/2002EP1196364A1 Process for the synthesis of (r)-1-(3,5-bis(trifluoromethyl)-phenyl)ethan-1-ol by asymmetric transfer hydrogenation
04/16/2002US6372940 Mixing at room temperature l(-)-carnitine inner salt, fumaric acid or l(+)-tartaric acid, 6-8% by weight of water, heating under stirring, cooling molten mass until completely solidified, grinding solidified mass to desired particle size
04/16/2002US6372906 Reacting camptothecin or homocamptothecin with silyl radical precursor under conditions to generate silyl radical
04/16/2002CA2358952A1 Novel olefination process to itaconate and succinate derivatives
04/11/2002WO2002028840A1 Process for preparation of integrin receptor antagonist intermediates
04/11/2002WO2001090055A3 A process for preparing biphenyl compounds
04/11/2002US20020042540 New 6,6'-bis-(1-phosphanorbornadiene) diphosphines, their preparation and their uses
04/11/2002US20020042356 (1S,6R)-2,2,6-Trimethylcyclohexyl methyl ketone and/or (1R,6S)-2,2,6-trimethylcyclohexyl methyl ketone, process for producing the same, and perfume composition containing the same
04/11/2002US20020042108 Process for preparing optically active 1-amino-4-(hydroxymethyl) cyclopent -2- ene derivatives
04/11/2002CA2424304A1 Process for preparation of integrin receptor antagonist intermediates
04/10/2002EP1194437A1 Diphosphine ligands for metal complexes
04/09/2002US6369243 Acid catalyst
04/09/2002US6369223 Using catalyst complex
04/04/2002WO2002026695A2 Preparation of enantiomerically-enriched cyclopropylalanine derivatives
04/04/2002US20020040164 For use in anxiolytic agents
04/04/2002US20020039961 Catalyst
04/04/2002DE10044793A1 Diphosphine Diphosphines
04/02/2002US6365605 Substituted hydrochromenopyrroles
04/02/2002CA2253906C Process for preparation of pyrimidine derivatives
03/2002
03/28/2002WO2002024705A1 Stereoselective process for preparing cyclohexyl amine derivatives
03/28/2002WO2002024671A1 Process for preparing optically active epoxides
03/28/2002WO2002004466A3 Catalyst for asymmetric (transfer) hydrogenation
03/28/2002WO2001090106A3 Tryasolyl tropane derivatives as ccr5 modulators
03/28/2002WO2001045484A3 An improved process for preparing simvastatin
03/28/2002US20020038053 For use in enantioselective reduction of prochiral ketones to chiral secondary alcohols
03/28/2002US20020038048 Catalytic asymmetric desymmetrization of meso compounds
03/28/2002US20020038042 Poly-beta-amino acids, preparation and use
03/28/2002CA2420210A1 Stereoselective process for preparing cyclohexyl amine derivatives
03/28/2002CA2400514A1 Process for preparing optically active epoxides
03/27/2002EP1191030A2 Phosphinite-oxazolines and metal complexes
03/27/2002EP0920410B1 Preparation of cyclohexene carboxylate derivatives
03/27/2002CN1342135A Preparation of carvone
03/26/2002CA2023645C Process for the enantioselective preparation of phenylisoserin derivatives
03/21/2002WO2002022623A1 4-cyclohexyl-1,3,2-oxazaborolidine chiral accessories
03/21/2002WO2002022529A2 1,4-diaryl-2,3-difluoro-2-butene insecticidal and acaricidal agents
03/21/2002US20020035285 Hydrogenation catalyst
03/21/2002US20020035283 Using hydrogenation catalyst complex containing ruthenium
03/21/2002CA2421861A1 1,4-diaryl-2,3-difluoro-2-butene insecticidal and acaricidal agents
03/21/2002CA2421777A1 4-cyclohexyl-1,3,2-oxazaborolidine chiral accessories
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