Patents
Patents for C40B 50 - Methods of creating libraries, e.g. combinatorial synthesis (5,219)
11/2001
11/29/2001US20010046682 Presence of a target reactant is determined by measuring the amount of material bound to an immobilized reactant
11/28/2001EP1156879A1 Multi-well array with adjustable plenum
11/28/2001CN1324450A Cobalamin assay
11/28/2001CN1324366A Solid phase synthesis, whereby the solid phase consists of two different substrates
11/27/2001US6322971 Generating preferential genetically engineered products; provide immobilized oligonucleotides, hybridize single stranded nucleotide sequences to immobilized nucleotide sequences, recover products
11/22/2001WO2001087351A1 Method for treatment of tumors using nucleic acid ligands to pdgf
11/22/2001WO2000056681A9 Thiourea and urea liquid-phase combinatorial libraries: synthesis and apoptosis induction
11/21/2001EP1154849A1 Bead picking apparatus and method
11/15/2001WO2000047540A9 Method and apparatus for synthesizing, purifying and characterizing combinatorial libraries
11/14/2001EP1153127A1 Method for producing polymers
11/13/2001US6316616 Parallel combinatorial approach to the discovery and optimization of catalysts and uses thereof
11/08/2001WO2001083826A2 Methods and reagents for assembling molecules on solid supports
11/08/2001WO2001083825A2 Colloid compositions for solid phase biomolecular analytical systems
11/08/2001US20010039020 Bead distributor detector
11/08/2001CA2408094A1 Colloid compositions for solid phase biomolecular analytical, preparative and identification systems
10/2001
10/31/2001EP1149291A1 Apparatus and method for concurrent chemical synthesis
10/31/2001EP1149110A2 Method for the light-controlled synthesis of biochips
10/31/2001EP1148947A1 Fibre array for contacting chemical species and methods for using and making same
10/30/2001US6309831 Method of manufacturing biological chips
10/25/2001WO2001079481A2 Methods of constructing display libraries of genetic packages for members of a diverse family of peptides
10/25/2001WO2001078895A2 Container and method for high volume treatment of samples on solid supports
10/25/2001US20010033375 Optical systems and methods for rapid screening of libraries of different materials
10/25/2001CA2798625A1 Novel methods of constructing libraries of genetic packages that collectively display the members of a diverse family of peptides, polypeptides or proteins
10/24/2001EP1147214A1 A novel method for designing protein kinase inhibitors
10/24/2001CN1319141A Enzyme activity screen with substrate replacement
10/23/2001US6306975 Radiation-grafted solid supports for chemical synthesis
10/23/2001US6306612 Methods of facilitating vascular growth
10/18/2001WO2001077684A2 Proteomic analysis using activity-based probe libraries
10/18/2001WO2001077668A2 Proteomic analysis using active-site directed probes
10/18/2001WO2001077315A1 Signal sequence trapping
10/18/2001CA2403296A1 Proteomic analysis using activity-based probe libraries
10/18/2001CA2402195A1 Signal sequence trapping
10/17/2001EP1146030A2 Combinatorial synthesis and analysis of organometallic compounds and catalysts
10/17/2001EP1144375A2 Synthesis of oligoketides
10/17/2001EP1144092A1 Integrated portable biological detection system
10/11/2001WO2001075097A2 Improvements to ribosome display
10/11/2001WO2001074849A2 Binding peptides for carcinoembryonic antigen (cea)
10/11/2001WO2001074130A2 A computer based method for identifying conserved invariant peptide motifs
10/11/2001CA2403242A1 Binding peptides for carcinoembryonic antigen (cea)
10/11/2001CA2402452A1 Improvements to ribosome display
10/11/2001CA2376710A1 A computer based method for identifying conserved invariant peptide motifs
10/10/2001EP1141712A1 Composite arrays utilizing microspheres
10/10/2001EP1141323A1 Mammalian lysophosphatidic acid acyltransferase
10/10/2001EP1140737A2 System and method for structure-based drug design that includes accurate prediction of binding free energy
10/10/2001EP0923590B1 Combinatorial method of identifying potential polymerisation catalysts of the organometallic type
10/09/2001US6300137 Method for synthesizing a specific, surface-bound polymer uniformly over an element of a molecular array
10/04/2001WO2001072771A2 Insulin and igf-1 receptor agonists and antagonists
10/04/2001WO2000017655A9 Water-soluble fluorescent semiconductor nanocrystals
10/04/2001EP1137805A1 Methods of facilitating vascular growth
10/04/2001EP1137802A1 Method for determining the activity of a substance using a functional test in vitro
10/04/2001EP1137690A2 Peg-based macromonomers, chemically inert polymers prepared therefrom and the use of these polymers for organic synthesis and enzyme reactions
10/04/2001EP1137661A1 Procollagen c-proteinase inhibitors
10/04/2001CA2402780A1 Insulin and igf-1 receptor agonists and antagonists
10/02/2001US6296810 Apparatus for DNA sequencing
09/2001
09/27/2001WO2001071346A2 Binding compounds for cc chemokine receptor 5 and methods for identifying them
09/27/2001WO2001070768A2 Receptor-binding compounds and method for identifying them
09/27/2001WO2001070765A1 Receptor-binding compounds and methods for identifying them
09/27/2001US20010024789 Identifying nucleic acid molecules which encode enzymes using nucleic acid-protein fusions
09/27/2001US20010024465 Communication system for automatic synthesis apparatus
09/27/2001DE10012615A1 Polymer/support solid phase reactants, useful for a range of organic reactions and purification processes comprise funtionalized polymer particles in the pores of a porous support
09/27/2001CA2404139A1 Binding compounds and methods for identifying binding compounds
09/27/2001CA2403788A1 Receptor-binding compounds and methods for identifying them
09/27/2001CA2403784A1 Binding compounds and methods for identifying binding compounds
09/26/2001EP1135413A2 Proteins that bind angiogenesis-inhibiting proteins, compoisitions and methods of use thereof
09/20/2001WO2001069211A1 Multi-wavelength array reader for biological assay
09/20/2001WO2001068805A2 Human olfactory receptors and genes encoding same
09/20/2001WO2001068599A2 Dosing form for reagents, use of said dosing form in organic chemical synthesis and production of said dosing form
09/20/2001CA2402746A1 Dosing form for reagents, use of said dosing form in organic chemical synthesis and production of said dosing form
09/20/2001CA2401406A1 Human olfactory receptors and genes encoding same
09/19/2001EP1133565A2 Generation of specific binding partners binding to (poly)peptides encoded by genomic dna fragments or ests
09/19/2001CN1313907A Process for preparing peptide nucleic acid probe using polymeric photoacid generator
09/18/2001US6290915 Apparatus for combinatorial chemistry for the synthesis of potential drug candidate molecules.
09/13/2001WO2001066244A1 Materials with silicon-containing layers for use in miniaturized arrays and methods of manufacturing
09/13/2001CA2401414A1 Materials with silicon-containing layers for use in miniaturized arrays and methods of manufacturing
09/12/2001EP1131471A2 A system for cell-based screening
09/12/2001EP1131440A2 Process for oxidising terpenes
09/07/2001WO2001034290A9 Array for generating combinatorial libraries
09/05/2001EP1129773A2 Methods for the in situ synthesis of a combinatorial library of supported catalyst materials
09/05/2001EP1128902A1 Sample sorting, conveying and receiving device for microspheres and method for operating the same
09/04/2001US6284538 Oligonucleotide used for diabetes and cancer treatment
08/2001
08/30/2001WO2001062983A1 Improved methods for generating catalytic proteins
08/30/2001US20010018512 For biopolymer
08/30/2001CA2399241A1 Improved methods for generating catalytic proteins
08/29/2001EP1127161A1 Method for making complementary oligonucleotide tag sets
08/29/2001EP1126912A1 Method and device for carrying out biochemical reactions with a high throughput
08/23/2001WO2001061332A1 Reaction and separation methods
08/23/2001WO2001061041A2 Multiple-site reaction device and method
08/23/2001CA2400439A1 Reaction and separation methods
08/23/2001CA2400207A1 Multiple-site reaction device and method
08/22/2001EP1124992A1 Methods for using co-regulated genesets to enhance detection and classification of gene expression patterns
08/22/2001EP1124991A1 Phytomics: a genomic-based approach to herbal compositions
08/21/2001US6277332 Apparatus for performing organic chemical reaction comprising liquid bath, transporting means for positioning reaction vessel containing paramagnetic bead therein, ultrasonic field means, magnetic field means, computer for controlling
08/16/2001WO2001058583A1 Apparatus for pre-determined mass sorting of positional-encoded solid phase synthesis supports
08/16/2001WO2001009389A3 Methods and apparatus for template capture and normalization for submicroliter reaction
08/16/2001EP1123390A2 Methods and reagents for isolating biologically active peptides
08/16/2001EP1123327A1 Solid supports containing scintillant
08/16/2001CA2366494A1 Apparatus for pre-determined mass sorting of positional-encoded solid phase synthesis supports
08/14/2001US6274091 Apparatus and process for multiple chemical reactions
08/09/2001WO2001057069A2 Targeting peptides
08/09/2001WO2001057067A1 Ligand for vascular endothelial growth factor receptor
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