Patents
Sitemap › C40 - Combinatorial technology › C40B - Combinatorial chemistry; Libraries, e.g. chemical libraries, in silico libraries › C40B 50 - Methods of creating libraries, e.g. combinatorial synthesis
Patents for C40B 50 - Methods of creating libraries, e.g. combinatorial synthesis (5,219)
05/1997
05/21/1997EP0774464A2 A template for solution phase synthesis of combinatorial libraries
05/14/1997EP0772623A1 Soluble combinatorial libraries
05/13/1997US5629177 Method for the enzymatic synthesis of oligonucleotides using thermostable 3'-phosphatase
05/02/1997EP0650393B1 Synthesis reaction column
04/1997
04/24/1997WO1997014706A1 Method for solution phase synthesis of oligonucleotides
04/24/1997CA2234159A1 Method for solution phase synthesis of oligonucleotides
04/02/1997EP0734397A4 Apparatus and method for polymer synthesis using arrays
04/01/1997US5616698 Reacting a saccharide having atleast one monosaccharide unit having hydroxyl group with polyoxyethylene glycol which is end capped both ends with methanol and a diol to form ether glycoside linkage, activation, glycosylation and capping
03/1997
03/27/1997WO1997010896A1 Apparatus and process for multiple chemical reactions
03/27/1997CA2232505A1 Apparatus and process for multiple chemical reactions
03/20/1997WO1997010363A1 Method for serial analysis of gene expression
03/18/1997US5612002 Apparatus and method for multiple simultaneous synthesis
03/13/1997CA2185379A1 Method for serial analysis of gene expression
03/12/1997EP0761822A2 Method for serial analysis of gene expression
03/11/1997US5609826 Methods and apparatus for the generation of chemical libraries
03/06/1997WO1997001755A3 High speed, automated, continuous flow, multi-dimensional molecular selection and analysis
02/1997
02/11/1997US5602000 Method for enzymatic synthesis of oligonucleotides
02/04/1997US5599695 Applying a print material onto a substrate for the biosynthesis of an oligonucleotide array
01/1997
01/16/1997WO1997001755A2 High speed, automated, continuous flow, multi-dimensional molecular selection and analysis
01/14/1997US5593642 Containment of solid support within a gas dispersion tube
01/02/1997EP0750629A1 Method and apparatus for performing multiple sequential reactions on a matrix
12/1996
12/19/1996WO1996040201A1 Combinatorial libraries of substrate-bound cyclic organic compounds
12/19/1996CA2221508A1 Combinatorial libraries of substrate-bound cyclic organic compounds
12/10/1996US5582801 Apparatus for multiple simultaneous synthesis
11/1996
11/12/1996US5574656 System and method of automatically generating chemical compounds with desired properties
10/1996
10/30/1996EP0739349A1 Polymer-supported solution synthesis of oligosaccharides
10/24/1996WO1996033010A1 Methods and apparatus for the generation of chemical libraries
10/24/1996CA2218359A1 Methods and apparatus for the generation of chemical libraries
10/22/1996US5567391 Multicompartment chemical reactors
10/15/1996US5565173 Apparatus and method for multiple simultaneous synthesis
10/02/1996EP0734397A1 Apparatus and method for polymer synthesis using arrays
08/1996
08/28/1996EP0728520A1 Printing molecular library arrays
08/13/1996US5545568 Solid phase and combinatorial synthesis of compounds on a solid support
07/1996
07/18/1996WO1996021859A1 Methods for production of large catalogued chemical libraries
07/18/1996CA2210071A1 Methods for production of large catalogued chemical libraries
06/1996
06/25/1996US5529756 Apparatus and method for polymer synthesis using arrays
05/1996
05/14/1996US5516664 Enzymatic synthesis of repeat regions of oligonucleotides
05/07/1996US5514569 Reducing inhibition of a nucleoside 5'-monophosphate on phosphodiesterase i by incubating the enzyme in the presence of a nucleoside 5'-monophosphate degrading enzyme
04/1996
04/03/1996EP0703825A1 Method and apparatus for conducting an array of chemical reactions on a support surface
03/1996
03/21/1996WO1996008781A1 System and method of automatically generating chemical compounds with desired properties
03/21/1996CA2199264A1 System and method of automatically generating chemical compounds with desired properties
03/05/1996US5496473 Apparatus for processing biopolymer-containing columns
02/1996
02/08/1996WO1996003418A1 Soluble combinatorial libraries
02/08/1996CA2195321A1 Soluble combinatorial libraries
12/1995
12/13/1995EP0686160A1 Solution and solid-phase formation of glycosidic linkages
12/12/1995US5474796 Immobilization
12/05/1995US5472672 Apparatus and method for polymer synthesis using arrays
11/1995
11/22/1995EP0682671A1 Methods and apparatus for dna sequencing
10/1995
10/31/1995US5463564 System and method of automatically generating chemical compounds with desired properties
10/24/1995US5460786 Cleaving peptied-solid support bond and removing side chain protecting groups
10/11/1995EP0675966A1 Novel oligonucleotide arrays and their use for sorting, isolating, sequencing, and manipulating nucleic acids
10/11/1995EP0675963A1 Method and apparatus for enzymatic synthesis of oligonucleotides
09/1995
09/21/1995WO1995025116A1 Method and apparatus for performing multiple sequential reactions on a matrix
09/21/1995CA2184589A1 Method and apparatus for performing multiple sequential reactions on a matrix
08/1995
08/31/1995WO1995018814A3 Polymer-supported solution synthesis of oligosaccharides
07/1995
07/26/1995EP0663856A1 Apparatus and method for multiple simultaneous synthesis
07/25/1995US5436143 Genetic engineering; one vessel; enzyme deactivation
07/13/1995WO1995018814A2 Polymer-supported solution synthesis of oligosaccharides
07/13/1995CA2180979A1 Polymer-supported solution synthesis of oligosaccharides
05/1995
05/31/1995EP0655135A1 Random generation and bio-specific selection of chemical compounds
05/30/1995US5419874 Synthesis reaction column
05/23/1995US5418944 Knowledge-based molecular retrieval system and method using a hierarchy of molecular structures in the knowledge base
05/03/1995EP0650393A1 Synthesis reaction column.
04/1995
04/27/1995WO1995011262A1 Apparatus and method for polymer synthesis using arrays
12/1994
12/22/1994WO1994029719A1 Random generation and bio-specific selection of chemical compounds
12/21/1994EP0624059A4 Combinatorial strategies for polymer synthesis.
12/08/1994WO1994027719A1 Method and apparatus for conducting an array of chemical reactions on a support surface
11/1994
11/17/1994EP0624059A1 Combinatorial strategies for polymer synthesis
10/1994
10/18/1994US5356596 Apparatus for isolation of synthetic peptide without mechanical loss
09/1994
09/01/1994WO1994019360A1 Solution and solid-phase formation of glycosidic linkages
09/01/1994DE4406491A1 Cleavage apparatus
08/1994
08/18/1994WO1994018218A1 Methods and apparatus for dna sequencing
08/18/1994CA2155186A1 Methods and apparatus for dna sequencing
08/03/1994EP0608779A1 Apparatus for peptide synthesis
07/1994
07/07/1994WO1994014972A1 Method and apparatus for enzymatic synthesis of oligonucleotides
07/07/1994CA2150670A1 Method and apparatus for enzymatic synthesis of oligonucleotides
06/1994
06/28/1994US5324483 Apparatus for multiple simultaneous synthesis
05/1994
05/11/1994EP0344177B1 Porous wafer for segmented synthesis of biopolymers
04/1994
04/28/1994WO1994008711A1 Apparatus and method for multiple simultaneous synthesis
03/1994
03/31/1994WO1994006291A1 Solid phase and combinatorial synthesis of compounds on a solid support
02/1994
02/22/1994US5288514 Linking a protected 2-aminobenzophenone to a substrate; deprotecting and reacting with an amino acid; cyclization; removal from substrate; screening
02/22/1994US5288464 Peptide synthesis
02/02/1994EP0580737A1 Heterodimeric receptor libraries using phagemids
01/1994
01/20/1994WO1994001213A1 Synthesis reaction column
11/1993
11/16/1993US5262530 Solid phase synthesis on polystyrene support, phosphoramidite chemistry
10/1993
10/14/1993WO1993020130A1 Apparatus for processing biopolymer-containing columns
10/05/1993CA1322745C Porous wafer for segmented synthesis of biopolymers
09/1993
09/02/1993WO1993017126A1 Novel oligonucleotide arrays and their use for sorting, isolating, sequencing, and manipulating nucleic acids
09/02/1993CA2130562A1 Novel oligonucleotide arrays and their use for sorting, isolating, sequencing, and manipulating nucleic acids
09/01/1993EP0558050A1 Apparatus and method for isolation of synthetic peptide without loss of reagents
08/1993
08/31/1993US5240680 Automated apparatus for use in peptide synthesis
07/1993
07/21/1993EP0551438A1 Surface expression libraries of randomized peptides
06/1993
06/24/1993WO1993012427A1 Automated apparatus for use in peptide synthesis
05/1993
05/27/1993WO1993009668A1 Combinatorial strategies for polymer synthesis
03/1993
03/03/1993EP0529573A1 Solid-phase synthesizer
12/1992
12/29/1992US5175209 Porous wafer for segmented synthesis of biopolymers
12/08/1992CA1311332C Bop reagent for solid phase peptide synthesis
10/1992
10/29/1992WO1992018619A1 Heterodimeric receptor libraries using phagemids
08/1992
08/05/1992EP0496902A1 Knowledge-based molecular retrieval system and method
03/1992
03/29/1992WO1992006176A1 Surface expression libraries of randomized peptides
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