Patents
Patents for C40B 50 - Methods of creating libraries, e.g. combinatorial synthesis (5,219)
08/2001
08/09/2001WO2001034290A3 Array for generating combinatorial libraries
08/09/2001CA2399058A1 Targeting peptides
08/09/2001CA2399022A1 Ligand for vascular endothelial growth factor receptor
08/08/2001EP1121196A2 Porous device
08/08/2001CN1307553A Process for solid phase synthesis of aldehyde ketone oxime, amine, hydroxamic acid and alpha, beta-unsaturated carboxylic acid and aldehyde compounds
08/02/2001WO2001055235A1 Molecularly imprinted polymer
08/02/2001DE10003631A1 New nucleoside derivatives with photolabile protecting groups, useful in oligonucleotide synthesis, particularly on solid phases, e.g. for hybridization testing
08/02/2001CA2398175A1 Molecularly imprinted polymer
07/2001
07/31/2001US6268177 An isolated polynucleotide; therapy and treatment of streptococcal infections, pneumonia, meningitis, sinusitis, conjunctivitis; screening for antibiotics
07/25/2001EP1117996A2 Method and device for producing and/or analyzing biochemical reaction supporting materials
07/25/2001EP1117678A1 Solid phase synthesis, whereby the solid phase consists of two different substrates
07/25/2001EP1117478A2 Support for a method for determining an analyte and a method for producing the support
07/25/2001CN1305443A Parallel combinatorial approach to discovery and optimization of catalysts and uses thereof
07/24/2001US6264891 For polymer; chemical libraries
07/19/2001WO2001051474A2 Polypharmacophoric agents
07/19/2001WO2001051206A1 Micro-titer plate with filter inserts and related fabrication method
07/19/2001US20010008759 Contacting target cells with member of antibody phage display library
07/18/2001EP1116036A1 Water-soluble fluorescent semiconductor nanocrystals
07/18/2001EP1116028A1 Ndp
07/18/2001EP1115887A1 Parallel selex
07/18/2001EP1115424A1 Method and measuring device for determining a plurality of analytes in a sample
07/17/2001US6262251 Product anchored sequencial synthesis (pass); an anchor group attached to the 5' end of the growing oligonucleotide product allows the coupled product to be separated from unreacted starting materials
07/12/2001WO2001050124A1 High efficiency mapping of molecular variations to functional properties
07/12/2001WO2001002588A3 Generation of specific binding partners binding to (poly)peptides encoded by genomic dna fragments or ests
07/11/2001EP1114323A1 Cobalamin assay
07/11/2001EP1114320A2 A system for cell-based screening
07/11/2001EP1113991A2 Formation of combinatorial arrays of materials using solution-based methodologies
07/11/2001EP1113986A2 Inventory control
07/05/2001WO1999064045A9 Novel therapeutic agents for membrane transporters
07/04/2001EP1112379A1 NOVEL AMPLICON IN THE 20q13 REGION OF HUMAN CHROMOSOME 20 AND USES THEREOF
07/03/2001US6255053 Detecting migratory nucleic acids; provide surface with dried bound nucleic acids, incubate with migratory nucleic acid, wash and detect bound migratory nucleotide sequences
06/2001
06/28/2001WO2001046693A2 Screening under isothermal denaturing conditions
06/28/2001WO2000076662A3 Microenabled chemical reaction in microfluidic chips
06/28/2001WO2000053744A9 End selection in directed evolution
06/28/2001US20010005588 A solid carrier where nucleotides are fixed by covalent bonding by a reaction of a reactive group on the carrier and a reactive group on the nucleotide using a transition metal catalyst; no blocking procedure; hydbridization;
06/28/2001CA2392777A1 Methods of identifying compounds that bind to target species under isothermal denaturing conditions
06/27/2001EP1110610A1 Micro-titer plate with filter inserts and method of making same
06/27/2001EP1110090A1 Multihued labels
06/27/2001EP1110086A1 Production of motif-specific and context-independent antibodies using peptide libraries as antigens
06/27/2001EP1109805A1 Inhibitors of bacterial nad synthetase
06/21/2001WO2001044472A1 Tnfr/opg-like molecules and uses thereof
06/21/2001WO2001043870A2 Column and row addressable high density biochip array
06/21/2001CA2394536A1 Tnfr/opg-like molecules and uses thereof
06/21/2001CA2393766A1 Column and row addressable high density biochip array
06/20/2001EP1107969A2 Collections of compounds
06/19/2001US6248540 Preparing array of activated metal-ligand compounds by providing different metal-binding ligands to different regions on substrate, providing metal ions to regions, then providing activators which are cocatalysts for polymerization
06/14/2001WO2001042501A1 Method for immobilisation
06/14/2001WO2001041931A2 Multilayered microfluidic devices for analyte reactions
06/14/2001WO2001041929A1 Device for binding a target molecule
06/14/2001WO2001041918A2 Oligonucleotide synthesizer using centrifugal force
06/14/2001WO2000032631A3 Proteins that bind angiogenesis-inhibiting proteins, compositions and methods of use thereof
06/14/2001CA2394374A1 Oligonucleotide synthesizer
06/14/2001CA2393690A1 Multilayered microfluidic devices for analyte reactions
06/14/2001CA2392830A1 Device for binding a target molecule
06/13/2001EP1105525A1 A process for preparing peptide nucleic acid probe using polymeric photoacid generator
06/13/2001EP1105521A1 Enzyme activity screen with substrate replacement
06/13/2001EP1105359A1 Solid phase synthesis of compounds by carbon-carbon bond forming mitsunobu reactions
06/07/2001WO2001040148A2 Systems and methods to facilitate multiple order combinatorial chemical processes
06/07/2001CA2392919A1 Systems and methods to facilitate multiple order combinatorial chemical processes
05/2001
05/31/2001WO2001038268A1 Apparatus and method for synthesizing combinatorial libraries
05/29/2001US6240374 Further method of creating and rapidly searching a virtual library of potential molecules using validated molecular structural descriptors
05/29/2001US6239273 Printing molecular library arrays
05/29/2001US6238929 Systems and methods for the synthesis of organic compounds
05/29/2001CA2156717C Solution and solid-phase formation of glycosidic linkages
05/25/2001WO2001036682A2 Long oligonucleotide arrays
05/25/2001WO2001036087A1 Examining chemical reactions
05/25/2001WO2000017413B1 Formation of combinatorial arrays of materials using solution-based methodologies
05/25/2001CA2388703A1 Long oligonucleotide arrays
05/23/2001EP1100885A1 Rapid subcloning using site-specific recombination
05/23/2001EP1100429A2 Apoptosis proteins
05/22/2001US6235469 Generation of transcriptional sequences associated with phage envelope protein; incubate and insert nucleotide sequences into expression vector, express gene coded in vector and recover polypeptides
05/17/2001WO2001034622A1 Combinatorial library synthesis and pharmaceutically active compounds produced thereby
05/17/2001WO2001034291A2 High-throughput synthesis, screening and characterization of combinatorial libraries
05/17/2001WO2001034290A2 Array for generating combinatorial libraries
05/17/2001CA2390441A1 Combinatorial library synthesis and pharmaceutically active compounds produced thereby
05/16/2001EP0859661B1 Apparatus and process for multiple chemical reactions
05/10/2001WO2000037718A9 Electrode array for development and testing of materials
05/09/2001EP1098004A2 Fixation of nucleotide derivatives to solid carrier
04/2001
04/26/2001WO2000078444A3 Method and device for carrying out biochemical reactions with a high throughput
04/12/2001WO2001025486A1 Methods for identifying rna binding compounds
04/12/2001WO2001025188A1 Novel carbamates and ureas
04/12/2001WO2000047540A3 Method and apparatus for synthesizing, purifying and characterizing combinatorial libraries
04/12/2001WO2000012123A3 Method and measuring device for determining a plurality of analytes in a sample
04/12/2001WO1999063939A9 Multibinding inhibitors of cyclooxygenase-2
04/12/2001CA2386540A1 Novel carbamates and ureas
04/12/2001CA2386239A1 Methods for identifying rna binding compounds
04/11/2001EP1089958A2 Process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and alpha,beta-unsaturated carboxylic acid and aldehyde compounds
04/11/2001EP1089749A1 Novel therapeutic agents for membrane transporters
04/05/2001CA2811455A1 Highly conserved genes and their use to generate species-specific, genus-specific, family-specific, group-specific and universal nucleic acid probes and amplification primers to rapidly detect and identify algal, archaeal, bacterial, fungal and parasitical microorganisms from clinical specimens for diagnosis
04/04/2001EP1088585A2 Method for automated chemical synthesis
04/04/2001EP1088029A1 Geminally substituted amines
04/04/2001EP1087929A1 Method for producing combinatory amine libraries
04/03/2001US6210894 Method and apparatus for conducting an array of chemical reactions on a support surface
03/2001
03/28/2001EP1086742A1 Combinatorial strategies for polymer synthesis
03/28/2001EP1086066A1 Muscarinic receptor antagonists
03/28/2001EP1085943A1 Three-dimensional array of supports for solid-phase parallel synthesis and method of use
03/28/2001EP1085941A2 Combinational method for microgram-scale production and characterization of crystalline and amorphous libraries of materials
03/28/2001EP1085890A1 Novel sodium channel drugs and uses
03/28/2001EP1085879A2 Multibinding agents that modulate the 5-ht transporter
03/28/2001EP1085845A2 Multibinding inhibitors of cyclooxygenase-2
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