| Patents for C40B 50 - Methods of creating libraries, e.g. combinatorial synthesis (5,219) |
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| 03/28/2001 | CN1289271A Method and apparatus for high-speed dot array dispensing |
| 03/22/2001 | WO2001019484A1 Purification device and purification method |
| 03/22/2001 | CA2388747A1 Purification device and purification method |
| 03/21/2001 | EP1083980A2 Modulation of molecular interaction sites on rna and other biomolecules |
| 03/20/2001 | US6203758 An arrangement of individually addressable micro-electrodes for performing biological, synthetic and diagnostic reactions such as nucleic acid hybridization, or antibody-antigen reactions; preperation of carbonhydrate polymers |
| 03/13/2001 | US6201104 Amino acid sequences of angiogenesis-inhibiting protein receptor; drug screening; isolation of angiogenesis related proteins |
| 03/08/2001 | WO2001015800A1 Method and device for performing operations at charged microlocations |
| 03/08/2001 | WO2000017655A8 Water-soluble fluorescent semiconductor nanocrystals |
| 03/07/2001 | EP1080435A1 Graphic design of combinatorial material libraries |
| 03/07/2001 | CN1286691A Oligonucleotide synthesis using high boiling point solvents |
| 03/01/2001 | WO2001013958A2 Drug conjugates and methods of designing the same |
| 03/01/2001 | CA2382202A1 Drug conjugates and methods of designing the same |
| 02/28/2001 | EP1077993A1 Generation of combinatorial libraries of compounds corresponding to virtual libraries of compounds |
| 02/27/2001 | US6194612 Template for solution phase synthesis of combination libraries |
| 02/27/2001 | US6194393 A glycoside containing an anomeric sulfoxide and nucleophilic functional groups and having potential glycosyl accepting/donating characteristics and an activating agent; rapid construction oligosaccharides; glycosylation; library |
| 02/22/2001 | WO2001013112A1 Melanocortin metallopeptide constructs, combinatorial libraries and applications |
| 02/22/2001 | WO2001012817A1 Evolution and use of enzymes for combinathorial and medicinal chemistry |
| 02/22/2001 | CA2380948A1 Evolution and use of enzymes for combinathorial and medicinal chemistry |
| 02/22/2001 | CA2379647A1 Melanocortin metallopeptide constructs, combinatorial libraries and applications |
| 02/14/2001 | EP1075455A2 Method and device for nonsynthetic deconvolution |
| 02/13/2001 | US6187164 Method for creating and testing a combinatorial array employing individually addressable electrodes |
| 02/08/2001 | WO2001009389A2 Methods and apparatus for template capture and normalization for submicroliter reaction |
| 02/08/2001 | WO2001008802A1 Low volume chemical and biochemical reaction system |
| 02/08/2001 | WO2000044717A3 Synthesis of oligoketides |
| 02/08/2001 | CA2380794A1 Methods and apparatus for template capture and normalization for submicroliter reaction |
| 02/08/2001 | CA2379969A1 Low volume chemical and biochemical reaction system |
| 02/07/2001 | EP1073905A1 Methods of selecting internalizing antibodies |
| 02/06/2001 | US6182499 Systems and methods for characterization of materials and combinatorial libraries with mechanical oscillators |
| 02/01/2001 | WO2001007457A1 Antisense modulation of pten expression |
| 02/01/2001 | WO2001007161A1 Method and apparatus for transferring small volume liquid samples |
| 02/01/2001 | WO2000021658A3 Porous device |
| 02/01/2001 | CA2693274A1 Peptide acceptor ligation methods |
| 02/01/2001 | CA2379659A1 Antisense modulation of pten expression |
| 02/01/2001 | CA2379275A1 Method and apparatus for transferring small volume liquid samples |
| 01/31/2001 | EP1071826A1 Identification of genetic targets for modulation by oligonucleotides and generation of oligonucleotides for gene modulation |
| 01/31/2001 | CN1282271A Method and apparatus for chemical synthesis |
| 01/25/2001 | WO2001005497A1 Method and apparatus for rapid screening of multiphase reactions |
| 01/24/2001 | EP1070254A1 Compositions and methods for detecting ligand-dependent nuclear receptor and coactivator interactions |
| 01/23/2001 | US6177558 During solid phase synthesis of nucleic acids, peptides and peptide nucleic acids on an open environment solid support, the polar aprotic solvent selected from mono- and dinitriles, glymes, diglymes, triglymes, and trimethylphosphates |
| 01/23/2001 | US6177248 Detecting expression of at least one gene down-stream from wt1 and comparing to wild type cells; a difference suggests mutation; diagnosis of cancer/tumor |
| 01/18/2001 | WO2000053744A3 End selection in directed evolution |
| 01/17/2001 | EP1068216A2 Libraries of oligomers labelled with different tags |
| 01/16/2001 | US6175006 Automated system for polynucleotide synthesis and purification |
| 01/11/2001 | WO2001002588A2 Generation of specific binding partners binding to (poly)peptides encoded by genomic dna fragments or ests |
| 01/11/2001 | WO2001002538A1 Substrates for nucleic acid immobilization onto solid supports |
| 01/10/2001 | EP1066295A2 Synthesis of compounds and libraries of compounds |
| 01/10/2001 | EP1066228A1 Parallel combinatorial approach to the discovery and optimization of catalysts and uses thereof |
| 01/09/2001 | US6171555 Reaction block docking station |
| 01/04/2001 | WO2000039751A3 System and method for structure-based drug design that includes accurate prediction of binding free energy |
| 01/02/2001 | US6168913 Coding combinatorial libraries with fluorine tags |
| 12/28/2000 | WO2000078444A2 Method and device for carrying out biochemical reactions with a high throughput |
| 12/21/2000 | WO2000077262A1 Synthetic ligation reassembly in directed evolution |
| 12/21/2000 | WO2000077194A1 A structured peptide scaffold for displaying turn libraries on phage |
| 12/21/2000 | WO2000076662A2 Microenabled chemical reaction in microfluidic chips |
| 12/21/2000 | CA2376232A1 A structured peptide scaffold for displaying turn libraries on phage |
| 12/20/2000 | EP1061128A1 Method and device for carrying out high throughput biochemical reactions |
| 12/14/2000 | WO2000075372A1 A process for preparing peptide nucleic acid probe using polymeric photoacid generator |
| 12/14/2000 | WO2000075175A1 Peptide having for fibrinogen fragment e activity, analogs, antibodies and uses thereof |
| 12/14/2000 | WO2000063419B1 Combinatorial chemical library supports having indicia at coding positions and methods of use |
| 12/14/2000 | CA2376078A1 Peptide having for fibrinogen fragment e activity, analogs, antibodies and uses thereof |
| 12/12/2000 | US6159681 Light-mediated method and apparatus for the regional analysis of biologic material |
| 12/06/2000 | EP1056726A1 Solid phase synthesis of 1-aminohydantoins |
| 11/30/2000 | WO2000071569A1 Minimal isolation peptide synthesis process using ion-exchange resins as scavenging agents |
| 11/30/2000 | WO2000071242A1 Synthesizer apparatus |
| 11/30/2000 | WO2000035931A3 Method for the light-controlled synthesis of biochips |
| 11/30/2000 | CA2373816A1 Minimal isolation peptide synthesis process using ion-exchange resins as scavenging agents |
| 11/29/2000 | EP1054727A1 Method for the combinatorial production and testing of heterogeneous catalysts |
| 11/29/2000 | EP1054726A2 Method and apparatus for chemical and biochemical reactions using photo-generated reagents |
| 11/28/2000 | US6151973 Bead picking apparatus and method |
| 11/23/2000 | WO2000007545A3 Apoptosis proteins |
| 11/16/2000 | WO2000023921A9 Graphic design of combinatorial material libraries |
| 11/15/2000 | EP1051245A1 Method of quality control in manufacturing processes |
| 11/09/2000 | WO2000067086A1 Synthesizing combinatorial libraries of materials |
| 11/09/2000 | WO2000066360A1 Multiple fluid sample processor with single well addressability |
| 11/09/2000 | CA2370573A1 Synthesizing combinatorial libraries of materials |
| 11/07/2000 | US6143252 Apparatus for multiple and parallel synthesis of different oligonucleotides |
| 10/26/2000 | WO2000063695A1 Encoding of microcarriers |
| 10/26/2000 | WO2000063419A1 Combinatorial chemical library supports having indicia at coding positions and methods of use |
| 10/26/2000 | WO2000013018B1 Support for a method for determining analytes and a method for producing the support |
| 10/26/2000 | CA2366093A1 Combinatorial chemical library supports having indicia at coding positions and methods of use |
| 10/25/2000 | EP1045819A1 Method for producing mass-coded combinatorial libraries |
| 10/24/2000 | US6136274 Matrices with memories in automated drug discovery and units therefor |
| 10/24/2000 | US6136269 Combinatorial kit for polymer synthesis |
| 10/19/2000 | WO2000061594A2 Nucleoside derivatives with photo-unstable protective groups |
| 10/19/2000 | WO2000061281A1 Encoding scheme for solid phase chemical libraries |
| 10/19/2000 | DE19915867A1 New nucleoside derivatives with photolabile protecting groups, useful in oligonucleotide synthesis, particularly on solid phases, e.g. for hybridization testing |
| 10/19/2000 | CA2367541A1 Encoding scheme for solid phase chemical libraries |
| 10/18/2000 | EP1044072A1 Method and apparatus for high-speed dot array dispensing |
| 10/17/2000 | US6133409 Reacting a solid support-bound n-alkylated hydroxamic acid with a carbon-nitrogen cleaving organometallic compund to liberate the product ketone |
| 10/17/2000 | US6132953 Combinatorial synthesis on soluble polyvalent supports having a discrete architecture |
| 10/17/2000 | CA2163781C Method and apparatus for conducting an array of chemical reactions on a support surface |
| 10/12/2000 | WO2000060345A1 Method for screening crystallization conditions in solution crystal growth |
| 10/12/2000 | WO2000017643A3 A system for cell-based screening |
| 10/12/2000 | CA2369935A1 Method for screening crystallization conditions in solution crystal growth |
| 10/11/2000 | EP1042337A2 Oligonucleotide synthesis using high boiling point solvents |
| 10/11/2000 | EP1042060A1 Method and apparatus for chemical synthesis |
| 10/05/2000 | WO2000058504A1 High throughput screening method for determining enantioselectivity |
| 10/05/2000 | DE10011400A1 Targeted photolytic deprotection of nucleoside derivatives, useful for synthesis of DNA chips, includes coating with a gel or viscous liquid before illumination |
| 10/05/2000 | CA2368749A1 High-throughput-screening method for determining enantioselectivity |
| 10/03/2000 | US6126904 Apparatus and methods for the preparation of chemical compounds |