Patents
Sitemap › C40 - Combinatorial technology › C40B - Combinatorial chemistry; Libraries, e.g. chemical libraries, in silico libraries › C40B 50 - Methods of creating libraries, e.g. combinatorial synthesis
Patents for C40B 50 - Methods of creating libraries, e.g. combinatorial synthesis (5,219)
12/1998
12/02/1998EP0880558A1 Combinatorial process for preparing substituted indane libraries
11/1998
11/17/1998US5837858 Method for polymer synthesis using arrays
11/12/1998WO1998050344A1 Substituted 3,3-diamino-2-propenenitriles, their preparation and use
11/12/1998CA2289099A1 Substituted 3,3-diamino-2-propenenitriles, their preparation and use
11/11/1998EP0876206A1 Method and apparatus for producing position-addressable combinatorial libraries
11/05/1998WO1998049187A1 Apparatus for synthesis of oligomers, especially peptoids, with reagent recycling
11/04/1998EP0874625A1 Indane derivatives for antipsychotic compositions
11/03/1998US5831070 Applying print material on substrate for biosynthesis of oligonucleotides
10/1998
10/28/1998CN1197413A Appts. and process for multiple chemical reactions
10/22/1998WO1998046786A1 Combinatorial libraries of peptidomimetic aminothioether acids
10/22/1998CA2286862A1 Combinatorial libraries of peptidomimetic aminothioether acids
09/1998
09/29/1998US5814700 Method for polymer synthesis in a reaction well
09/24/1998WO1998041534A2 Multifunctional ceramic particles as supports for solid phase and combinatorial synthesis
09/24/1998WO1998041531A2 Solvent for biopolymer synthesis, solvent microdroplets and methods of use
09/24/1998CA2284211A1 Solvent for biopolymer synthesis, solvent microdroplets and methods of use
09/22/1998US5810989 Photoelectric synthesis of DNA or protein probe arrays
09/16/1998EP0863910A1 Method for solution phase synthesis of oligonucleotides
09/11/1998WO1998039099A1 Apparatus and methods for the preparation of chemical compounds
09/02/1998CN1192154A Combinatorial libraries of substrate-bound cyclic organic compounds
08/1998
08/27/1998WO1998036829A1 Reaction apparatus for solid phase synthesis and method of using the same
08/26/1998EP0859661A1 Apparatus and process for multiple chemical reactions
08/20/1998WO1998035753A1 Automated chemical synthesis device
08/11/1998US5792839 Reacting glcosyl donor having anomeric sulfoxide group and glycosyl acceptor at low temperature
08/11/1998US5792430 Solid phase organic synthesis device with pressure-regulated manifold
08/06/1998WO1998033586A1 Apparatus and method for diverse chemical synthesis using multi-dimension movable arrays
08/06/1998CA2280484A1 Apparatus and method for diverse chemical synthesis using multi-dimension movable arrays
07/1998
07/30/1998WO1998015825A3 Matrices with memories in automated drug discovery and units therefor
07/23/1998WO1998032017A2 Modulators of insulin receptor activity
07/23/1998WO1998031732A2 Methods for radiation grafting to polymeric surfaces
07/23/1998CA2278023A1 Modulators of insulin receptor activity
07/16/1998WO1998030578A1 Method for solution phase synthesis of oligonucleotides and peptides
07/16/1998CA2277415A1 Method for solution phase synthesis of oligonucleotides and peptides
07/14/1998US5779985 For performing chemical synthesis reaction on paramagnetic bead
06/1998
06/25/1998WO1998015501A3 Systems and methods for characterization of materials and combinatorial libraries with mechanical oscillators
06/25/1998CA2589337A1 Methods and compositions for polypeptide engineering
06/23/1998US5770157 Methods and apparatus for the generation of chemical libraries
06/16/1998US5766556 Apparatus and method for multiple simultaneous synthesis
06/09/1998US5763263 Method and apparatus for producing position addressable combinatorial libraries
06/02/1998US5759817 Heterodimeric receptor libraries using phagemids
06/02/1998US5759779 Detecting mutations in a polynucleotide analyte, combinatorial chemistry, array of capillary tubes with position addressable oligonucleotides adhered to inner wall
05/1998
05/22/1998WO1998020967A1 Chemical amplification for the synthesis of patterned arrays
05/14/1998CA2702219A1 High density immobilization of nucleic acids
04/1998
04/30/1998WO1998017382A1 System and methods for parallel synthesis of organic compounds
04/16/1998WO1998015969A2 Mass spectrometers and methods for rapid screening of libraries of different materials
04/16/1998WO1998015825A2 Matrices with memories in automated drug discovery and units therefor
04/16/1998WO1998015813A1 Infrared spectroscopy and imaging of libraries
04/16/1998WO1998015805A1 Optical systems and methods for rapid screening of libraries of different materials
04/16/1998WO1998015501A2 Systems and methods for characterization of materials and combinatorial libraries with mechanical oscillators
04/16/1998CA2267769A1 Matrices with memories in automated drug discovery and units therefor
04/15/1998EP0835446A2 High speed, automated, continuous flow, multi-dimensional molecular selection and analysis
04/09/1998WO1998014641A1 Potential masking systems and methods for combinatorial library synthesis
04/02/1998WO1998013137A1 Systems and methods for the synthesis of organic compounds
03/1998
03/26/1998WO1998012559A1 Spatially addressable combinatorial chemical arrays in cd-rom format
03/26/1998WO1998012156A1 Combinatorial approach for generating novel coordination complexes
03/26/1998CA2301230A1 Spatially addressable combinatorial chemical arrays in cd-rom format
03/25/1998EP0750629A4 Method and apparatus for performing multiple sequential reactions on a matrix
02/1998
02/19/1998WO1998006490A1 Solid phase organic synthesis device with pressure-regulated manifold
02/18/1998CN1173921A Methods for prodn. ef large catalogued chemical libraries
02/04/1998EP0821619A1 Methods and apparatus for the generation of chemical libraries
02/03/1998US5714127 System for multiple simultaneous synthesis
01/1998
01/29/1998WO1998003521A1 Combinatorial synthesis and analysis of organometallic compounds and catalysts
01/29/1998WO1998003452A1 Polymers as a support for combinatorial synthesis
01/29/1998CA2261051A1 Polymers as a support for combinatorial synthesis
01/14/1998EP0818744A2 Process for selecting candidate drug compounds
01/14/1998EP0682671A4 Methods and apparatus for dna sequencing.
12/1997
12/30/1997US5703792 Three dimensional measurement of molecular diversity
12/30/1997US5702672 Apparatus and method for multiple simultaneous synthesis
12/23/1997US5700916 Solution and solid-phase formation of glycosidic linkages
12/04/1997WO1997045115A1 Pharmaceutical for treatment of neurological and neuropsychiatric disorders
12/04/1997WO1997041139A3 A combinatorial protecting group strategy for multifunctional molecules
12/04/1997CA2619901A1 Pharmaceutical for treatment of neurological and neuropsychiatric disorders
11/1997
11/27/1997WO1997044134A1 Jet droplet device and method
11/06/1997WO1997041139A2 A combinatorial protecting group strategy for multifunctional molecules
11/04/1997US5684711 System, method, and computer program for at least partially automatically generating chemical compounds having desired properties
10/1997
10/29/1997EP0803063A1 Methods for production of large catalogued chemical libraries
10/14/1997US5677195 Forming oligonucleotides or peptides by forming flow channels in substrate surface, each of flow channels comprising walls which form fluid-tight seals with surface and a flow intake and outlet, flowing nucleic acids through channels to bind
10/07/1997US5674743 Cleaving single nucleotide from dna strand; incorporating in fluorescence-enhancing matrix; irradiating; identifying; repeating
09/1997
09/25/1997WO1997035198A1 Methods for spatially-dispersed positionally-encoded combinatorial library synthesis
09/25/1997CA2249419A1 Methods for spatially-dispersed positionally-encoded combinatorial library synthesis
09/10/1997EP0794001A2 Automated system for polynucleotide synthesis and purification
08/1997
08/28/1997WO1997031127A1 Technique for representing combinatorial chemistry libraries resulting from selective combination of synthons
08/28/1997CA2247106A1 Technique for representing combinatorial chemistry libraries resulting from selective combination of synthons
08/19/1997US5658802 Method and apparatus for making miniaturized diagnostic arrays
08/19/1997US5658727 Filamentous phage encapsulating genome encoding ligand-binding antibody comprising first and second polypeptides where first polypeptide is fused to carboxy terminal phage membrane anchor domain
08/12/1997US5656741 Process and reagents for processing synthetic oligonucleotides
07/1997
07/31/1997WO1997027559A1 Method of creating and searching a molecular virtual library using validated molecular structure descriptors
07/31/1997DE19602464A1 Apparatus for multiple, simultaneous and parallel synthesis of chemicals
07/30/1997EP0703825B1 Method and apparatus for conducting an array of chemical reactions on a support surface
07/24/1997WO1997026540A1 Minifiltration method and apparatus
07/24/1997WO1997026300A1 Combinatorial process for preparing substituted indane libraries
07/24/1997WO1997025983A1 Indane derivatives for antipsychotic compositions
07/24/1997CA2243717A1 Indane derivatives for antipsychotic compositions
07/24/1997CA2243500A1 Combinatorial process for preparing substituted indane libraries
07/15/1997US5648271 Method for evaporating solvent using filter
07/02/1997EP0781436A1 System and method of automatically generating chemical compounds with desired properties
06/1997
06/17/1997US5639866 Single-step formation of multiple glycosidic linkages
06/11/1997EP0777492A1 Combinatorial libraries of substrate-bound cyclic organic compounds
06/05/1997WO1997019749A1 Method and apparatus for producing position-addressable combinatorial libraries
06/05/1997CA2238303A1 Method and apparatus for producing position-addressable combinatorial libraries
06/03/1997US5635612 Method of forming multiple glycosidic linkages in a single step
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