Patents
Sitemap › C40 - Combinatorial technology › C40B - Combinatorial chemistry; Libraries, e.g. chemical libraries, in silico libraries › C40B 50 - Methods of creating libraries, e.g. combinatorial synthesis
Patents for C40B 50 - Methods of creating libraries, e.g. combinatorial synthesis (5,219)
10/2003
10/23/2003US20030198948 Synthetic nucleic acid double strands of optional sequence
10/23/2003CA2481355A1 Hydrophobic zone device
10/22/2003EP1354079A2 Methods of searching for solid forms and screening a sample according to its forms
10/22/2003EP1353955A2 High affinity antibodies
10/22/2003EP0963246B1 Automated chemical synthesis device
10/21/2003US6635470 Fiber array and methods for using and making same
10/16/2003WO2003033127A3 Methods of patterning a monolayer
10/16/2003WO2003012042A3 Ratio-based oligonucleotide probe selection
10/16/2003US20030194741 Three blocking groups are independently removable under 3 different conditions; using new protection schemes and solid phase synthesis, oligonucleotides are obtained in 5' to 3' direction using phosphoamidites and avoiding depurination
10/16/2003US20030194715 Photoactivatable silane compounds and methods for their synthesis and use
10/16/2003US20030194709 A genetic analysis chip having a hydrophobic zone, bounding a hydrophilic zone in which a genetic sample can be analyzed
10/15/2003EP1352243A2 Perfluoro sulfonyl halides and related species as polymer support modifiers
10/09/2003WO2003083475A1 Gel having biosubstance fixed thereto and microarray utilizing the gel
10/09/2003WO2003083440A2 Methods and compositions for detection and quantitation of nucleic acid analytes
10/09/2003WO2003083063A2 Common ligand mimics: naphtoates
10/09/2003US20030190758 Detecting sampling in capillary tube; solidification; analyzing, classification
10/09/2003US20030190260 Useful for rapidly making, screening and characterizing an array of reaction materials in which process conditions are monitored and controlled
10/09/2003CA2481323A1 Biological substance-immobilized gel and microarray using the same
10/09/2003CA2480673A1 Methods and compositions for detection and quantitation of nucleic acid analytes
10/08/2003EP1350855A2 Array based hybridization assays
10/08/2003EP1350214A2 Methods and apparatus for designing high-dimensional combinatorial experiments
10/02/2003WO2002099003A3 Parallel reactor system and method
10/02/2003US20030186427 Apparatus for selectively converting photogenerated reagent precursors to photogenerated reagents associated with parallel synthesis of molecular sequence arrays on solid surfaces
10/02/2003US20030186252 Array based hybridization assays employing enzymatically generated labeled target nucleic acids and compositions for practicing the same
10/02/2003US20030186223 Modular recombinatorial display libraries
10/01/2003EP1348482A2 Modified solid carrier and DNA detection device
10/01/2003EP1348113A2 Nanoscale molecular arrayer
10/01/2003CN1446264A Method and device of testing nudein hybride pair on gene chip by four-dimensional paramerter
09/2003
09/25/2003WO2003078583A2 Optimization of crossover points for directed evolution
09/25/2003WO2003078045A2 Microcapillary hybridization chamber
09/24/2003EP0655135B1 Random generation and bio-specific selection of chemical compounds
09/23/2003US6623860 Multilevel flow structures
09/23/2003US6623659 Separation of olefins from paraffins using ionic liquid solutions
09/18/2003WO2003076940A2 Acyl fluoride activation of carboxysilyl-coated glass substrates
09/18/2003WO2002099382A3 Multiplexing method
09/18/2003US20030176980 System, method, and product for dynamic noise reduction in scanning of biological materials
09/18/2003US20030175750 Identifying one or more of a plurality of sequences differing by one or more single-base changes; restriction fragment length polymorphisms
09/18/2003US20030175409 Printing molecular library arrays
09/18/2003US20030175164 Devices, systems, and methods of manifolding materials
09/18/2003US20030175157 Fluid handling methods and systems
09/17/2003EP1266035A4 Improved methods for generating catalytic proteins
09/17/2003CN1443201A Arrays of N aqueous polymer dispersions and M formulations of aqueous polymer dispersions
09/16/2003US6620796 Combinatorial library synthesis and pharmaceutically active compounds produced thereby
09/12/2003WO2003074678A2 Modular recombinatorial display libraries
09/12/2003WO2002082080A3 Method for producing a plurality of identical copies of a two-dimensional test array of probe molecules
09/12/2003WO2001046693A3 Screening under isothermal denaturing conditions
09/12/2003CA2477947A1 Modular recombinatorial display libraries
09/11/2003US20030170640 Immobilization; fluorination
09/11/2003US20030170622 Generation of specific binding partners binding to (poly)peptides encoded by genomic dna fragments or ests
09/11/2003US20030170146 Liquid handling system for crystallization of macromolecules, such as proteins
09/10/2003EP1341598A2 Process for applying material layers to shaped bodies
09/04/2003WO2003072240A1 Apparatus for treatment of light-sensitive biopolymers
09/04/2003US20030166002 Formed by reductively aminating triazine, then adding amine to cyanuric chloride; for proteomics and sensors
08/2003
08/28/2003WO2003048314A3 Direct write nanolithographic deposition of nucleic acids from nanoscopic tips
08/28/2003US20030162210 Novel oligonucleotide arrays and their use for sorting, isolating, sequencing, and manipulating nucleic acids
08/27/2003EP1337342A1 Microsystem for the dielectric and optical manipulation of particles
08/27/2003EP1110086A4 Production of motif-specific and context-independent antibodies using peptide libraries as antigens
08/21/2003WO2003069319A2 Automated macromolecular crystallization screening
08/21/2003WO2003068982A1 Bio-cell chip
08/21/2003WO2002077772A3 Method and system for high-throughput screening
08/21/2003US20030157566 Combinatorial processes for preparing an array of multi aqueous polymer dispersions by emulsion polymerization
08/21/2003US20030157529 Methods for determining transcriptional activity
08/19/2003US6608192 Collections of compounds
08/14/2003WO2003067515A1 Apparatus and method for designing proteins and protein libraries
08/14/2003WO2003066678A1 Common protein surface shapes and uses therefor
08/14/2003WO2003066217A1 Arrays of capillary tubes for chemical and biological use
08/14/2003WO2003066212A2 Microarray synthesis instrument and method
08/14/2003US20030153523 Screening library of test compounds, each of which is attached to a solid support, with a dye-labeled RNA molecule to form a dye-labeled target RNA:support-attached test compound complex
08/14/2003US20030153006 Immersion particle carrier in unsaturated monomer; addition polymerization
08/14/2003US20030150739 Electrospraying solutions of substances for mass fabrication of chips and libraries
08/14/2003US20030150375 Automated macromolecular crystallization screening
08/14/2003CA2476274A1 Common protein surface shapes and uses therefor
08/13/2003EP1334768A2 Multi-directional deposition in array fabrication
08/12/2003US6605449 Saturation mutagenesis to produce progenitor polynucleotide library
08/12/2003CA2348132C A system for cell-based screening
08/07/2003WO2003065040A1 Method of fixing biomolecule to carrier
08/07/2003WO2003065038A2 Apparatus for synthesis or arrays of dna probes using micromirrors, prism and k aleidoscopic element
08/07/2003WO2003065030A1 Fluid handling methods and systems
08/07/2003WO2003064585A1 Devices, systems, and methods of manifolding materials
08/07/2003WO2003064027A2 Correction for illumination non-uniformity during the synthesis of arrays of oligomers
08/07/2003WO2003064026A1 Pre-patterned substrate, device and method for optical synthesis of dna probes
08/07/2003US20030149533 Method of superposing molecular structures of compounds
08/07/2003US20030148502 Comprises flow cell container for synthesizing immobilized oligomer probes
08/07/2003US20030148304 Method for immobilisation
08/07/2003US20030148269 Centrifugally-enhanced method of determining ligand/target affinity
08/07/2003CA2474091A1 Method of fixing biomolecule to carrier
08/06/2003EP1331998A1 Combinatorial synthesis system
08/05/2003US6602714 Viscosity and mass sensor for the high-throughput synthesis, screening and characterization of combinatorial libraries
07/2003
07/31/2003US20030143756 Multi-directional deposition in array fabrication
07/31/2003US20030143724 Prepatterned substrate for optical synthesis of DNA probes
07/31/2003US20030143630 Apparatus and method for synthesizing
07/31/2003US20030143550 Correction for illumination non-uniformity during the synthesis of arrays of oligomers
07/31/2003US20030143132 For constructing arrays of DNA sequences using image of a micromirror array projected on a reaction site
07/31/2003US20030143131 Device for chemical and biochemical reactions using photo-generated reagents
07/30/2003EP1105525A4 A process for preparing peptide nucleic acid probe using polymeric photoacid generator
07/30/2003EP1054726B1 Apparatus for chemical and biochemical reactions using photo-generated reagents
07/24/2003WO2003059516A1 Reaction vessel for carrying out array processes
07/24/2003US20030138829 Comprises flow channels formed within an elastomeric material for use in thermocycling applications such as nucleic acid amplification, genotyping and gene expression analysis; high throughput assays
07/24/2003US20030138376 A compressed tablets comprising an embedded polymer matrix, insoluble and disintegrable in the solvents, removed by filtration, separation from a formed soluble product
07/24/2003US20030138363 Device for chemical and biochemical reactions using photo-generated reagents
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