| Patents for C40B 50 - Methods of creating libraries, e.g. combinatorial synthesis (5,219) |
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| 09/15/2004 | EP1456668A2 Protein arrays for allelic variants and uses thereof |
| 09/15/2004 | EP1165834B1 High throughput screening method for determining enantioselectivity |
| 09/14/2004 | US6790620 Small volume chambers |
| 09/10/2004 | WO2004076059A2 System and process for the synthesis of polymers |
| 09/09/2004 | US20040175760 Analysis of chemical data from images |
| 09/09/2004 | US20040175734 Support for analyte determination methods and method for producing the support |
| 09/09/2004 | US20040174171 Fast characterizing method for triboelectrical properties |
| 09/09/2004 | DE10308857A1 Apparatus for the synthesis in situ of oligonucleotides on a substrate, as individual libraries on chips, uses a four-stage phosphor amidite synthesis cycle |
| 09/08/2004 | EP1454177A1 Multi-substrate biochip unit |
| 09/08/2004 | EP1453973A1 Methods for determining transcriptional activity |
| 09/08/2004 | EP1077993A4 Generation of combinatorial libraries of compounds corresponding to virtual libraries of compounds |
| 09/07/2004 | US6789040 System, method, and computer software product for specifying a scanning area of a substrate |
| 09/07/2004 | US6787313 Dry deposit nondestructive particles on preferential surface; for use in the generation biochip microarrays |
| 09/07/2004 | US6787141 Peptide having for fibrinogen fragment E activity, analogs, antibodies and uses thereof |
| 09/02/2004 | WO2004073988A2 Printing method and apparatus |
| 09/02/2004 | WO2003083440A3 Methods and compositions for detection and quantitation of nucleic acid analytes |
| 09/02/2004 | US20040171142 Method for producing a plurality of identical copies of a two-dimensional test array of probe molecules |
| 09/02/2004 | US20040170988 Modified solid carrier and DNA detection device |
| 09/02/2004 | CA2824150A1 Expression of class 2 mannosidase and class iii mannosidase in lower eukaryotic cells |
| 09/02/2004 | CA2824126A1 Expression of class 2 mannosidase and class iii mannosidase in lower eukaryotic cells |
| 09/02/2004 | CA2731504A1 Combinatorial dna library for producing modified n-glycans in lower eukaryotes |
| 09/02/2004 | CA2714863A1 Methods of constructing biodiverse gene fragment libraries and biological modulators isolated therefrom |
| 09/01/2004 | CN1164769C Method and device of testing nudein hybride pair on gene chip by four-dimensional paramerter |
| 08/26/2004 | WO2004073048A2 Apparatus and methods for forming films on substrates |
| 08/26/2004 | US20040166516 Providing a candidate catalytic protein fusion molecule, including a catalytic protein linked to both its nucleic acid coding sequence and a substrate; determining whether candidate catalytic protein catalyzes a reaction of the substrate by assaying for an alteration in molecular size, charge etc. |
| 08/26/2004 | US20040166494 Preparing optically clear, solid, two-dimensional (2D) nitrocellulose matrix assay for genomic and protein analysis |
| 08/26/2004 | DE10304855A1 Vorrichtung und Verfahren zum simultanen Agitieren von Reaktionsmischungen Device and method for the simultaneous agitation of the reaction mixtures |
| 08/25/2004 | CN1524181A Perfluoro sulfonyl halides and related species as polymer support modifiers |
| 08/24/2004 | US6780981 Making a set of labelled compounds by the use of particulate support, comprises dividing the support into lots, performing a different chemical reaction on each lot of the support |
| 08/19/2004 | WO2004069401A2 Device and process for the simultaneous agitation of reaction mixtures |
| 08/19/2004 | WO2004043588A3 Production of polymeric microarrays |
| 08/19/2004 | WO2003087166A3 Photoactivatable silane compounds and methods for their synthesis and use |
| 08/19/2004 | US20040161741 Microarray comprising immobilized nucleotide sequences and/or derivatives for quantifying RNA expression products |
| 08/18/2004 | CN1521275A Multiple arrays with surface energy transition to maintain separation of samples on the arrays |
| 08/12/2004 | WO2004015133A3 Combinatorial synthesis system |
| 08/12/2004 | US20040157788 production of antibodies containing K light chains, in order to provide high affinity reproducibly |
| 08/12/2004 | US20040157318 Device for automatically dispensing microscopic amounts of liquid |
| 08/12/2004 | US20040157291 expressed sequence tag (EST); of fusion proteins comprising the first N-terminal domain of the geneIII protein of filamentous phage as fusion partner for the expression of a fused (poly)peptide/protein |
| 08/12/2004 | US20040155668 High throughput mechanical property testing of materials libraries using capacitance |
| 08/11/2004 | EP1445015A1 Fast characterizing method for triboelectrical properties |
| 08/11/2004 | EP1444235A1 Reverse-turn mimetics and method relating thereto |
| 08/11/2004 | EP1116036B1 Water-soluble fluorescent semiconductor nanocrystals |
| 08/10/2004 | US6774209 Synthetic, isolated polypeptides overexpressed in adenocarcinomas of endodermally derived digestive system epithelia and fetal colon; for imaging |
| 08/10/2004 | US6773888 Photoactivatable silane compounds and methods for their synthesis and use |
| 08/05/2004 | WO2004065000A1 Chemical reaction monitor |
| 08/05/2004 | US20040152083 Multiple arrays with surface energy transition to maintain separation of samples on the arrays |
| 08/05/2004 | US20040152081 Viscosity control during polynucleotide synthesis |
| 08/05/2004 | US20040151635 Biopolymer detector; computer control |
| 08/04/2004 | EP1443328A2 Cobalamin assay |
| 08/04/2004 | EP1442790A1 Viscosity control during polynucleotide synthesis |
| 08/04/2004 | EP1442789A1 Multiple arrays |
| 08/04/2004 | EP1442134A2 Method for producing and identifying soluble protein domains |
| 08/03/2004 | US6770754 Functionalized polymeric or silica base material; do not include a pre-attached nucleoside, and therefore can be used universally for any na or rna synthesis; fast cleavage and dephosphorylation at relatively low temperatures |
| 08/03/2004 | US6770482 Comprises providing a reaction substrate having a plurality of substrate reservoirs adapted to receive a reactant system partially embodied in a liquid |
| 08/03/2004 | US6770436 Radiation-activated catalysts (racs), autocatalytic reactions, and protective groups are employed to achieve a highly sensitive, high resolution, radiation directed combinatorial synthesis of pattern arrays of diverse polymers |
| 07/22/2004 | WO2004060550A1 Batch reactor with injection system |
| 07/22/2004 | US20040142355 Methods, compositions and libraries pertaining to PNA dimer and PNA oligomer synthesis |
| 07/21/2004 | EP1438435A2 Methods for blocking nonspecific hybridizations of nucleic acid sequences |
| 07/21/2004 | EP1438433A2 Detection of dna hybridization on surfaces |
| 07/21/2004 | EP1438128A2 Methods of patterning a monolayer |
| 07/20/2004 | CA2245935C Method of creating and searching a molecular virtual library using validated molecular structure descriptors |
| 07/15/2004 | WO2004059010A1 Releasable polymer arrays |
| 07/15/2004 | WO2003087391A3 Hydrophobic zone device |
| 07/15/2004 | US20040137606 Apparatus for preparing high density DNA or bipolymer microarrays by irradiating specific cells with ultraviolet light |
| 07/15/2004 | US20040137543 Bacteriotoxin adsorbents and method of screening the same |
| 07/15/2004 | US20040137469 Peptide Nucleic Acids (PNA); an acid forming cleavable linker and a PNA dimer comprising an N-terminal base labile protecting group, cleavably linked to the solid support through the cleavable linker |
| 07/15/2004 | CA2510645A1 Releasable polymer arrays |
| 07/14/2004 | EP1437416A1 Method and equipment to monitor nucleic acid hybridization on a dna chip using four-dimensional parameters |
| 07/08/2004 | WO2002077772B1 Method and system for high-throughput screening |
| 07/08/2004 | US20040131505 For liquid sample; discharging means; high speed, accuracy |
| 07/07/2004 | CN1156584C Methods and apparatus for template capture and normalization for submicroliter reaction |
| 07/07/2004 | CN1156583C Parallel ligand index concentration system generating method |
| 07/06/2004 | US6759510 Useful for rapid identification of biologically active compounds ;include cell-growth affecting peptides and peptides which enhance or inhibit production of cellular proteins |
| 07/01/2004 | WO2003093785B1 Biochips with surfaces coated with polysaccharide based hydrogels |
| 06/30/2004 | EP1432989A1 Randomly ordered arrays and methods of making and using |
| 06/30/2004 | EP1432980A2 Protein design automation for protein libraries |
| 06/30/2004 | EP1432527A2 Biological control of nanoparticles |
| 06/30/2004 | EP1127161A4 Method for making complementary oligonucleotide tag sets |
| 06/29/2004 | US6756492 Used for sequencing nucleic acids efficiently; photolabile group contains 2-nitrophenyl moiety |
| 06/29/2004 | US6756195 Polymerization method from the combinatorial synthesis and analysis of organometallic compounds and catalysts |
| 06/29/2004 | US6756109 Combinatorial electrochemical deposition and testing system |
| 06/24/2004 | US20040121448 Apparatus for discharging one or more chemical components into a reaction chamber and screening two or more samples under controlled condition; high throughput assay; screening data libraries |
| 06/17/2004 | US20040116685 Method for solution phase synthesis of oligonucleotides |
| 06/17/2004 | US20040115098 Multi-well apparatus |
| 06/16/2004 | EP1428810A2 Libraries of oligomers labelled with different tags |
| 06/16/2004 | EP1427805A2 Surface assembly for immobilizing dna capture probes in genetic assays using enzymatic reactions to generate signal in optical bio-discs and methods relating thereto |
| 06/16/2004 | EP1268566B1 Porous polymer/carrier solid phase reactants, method for producing same and the use thereof |
| 06/16/2004 | EP0580737B1 Heterodimeric receptor libraries using phagemids |
| 06/15/2004 | US6750064 Detecting sampling in capillary tube; solidification; analyzing, classification |
| 06/15/2004 | US6749756 Tagging series of pure compounds with alkylfluorosilanes of varied fluorine content; preforming combined synthesis and chromatographing |
| 06/10/2004 | WO2004031366A3 Manufacturing method and readout system for biopolymer arrays |
| 06/10/2004 | US20040110211 Microarray with hydrophobic barriers |
| 06/10/2004 | US20040110133 Using a chemically amplified polymer matrix and a photo carboxylic acid generator; exposing to patterned radiation to expose acid labile groups in reaction areas, coupling a monomer to a biopolymer to said reaction areas |
| 06/10/2004 | US20040109935 Biosynthesis of polymer array using acid generator; exposure substrate to patterned radiation |
| 06/09/2004 | EP1113991B1 Formation of combinatorial arrays of materials using solution-based methodologies |
| 06/09/2004 | CN1152749C Method and apparatus for distributing liquid reagent on substrate |
| 06/08/2004 | US6746845 Oligonucleotide for use as diagnostic tool in genetic engineering |
| 06/03/2004 | US20040106151 support-bound moieties and activated supports; utility in solid phase or solution phase synthesis, biosynthesis, catalysis, purification, analysis, and identification and screening; each moiety and activated support includes activator and linker |
| 05/27/2004 | WO2004043588A2 Production of polymeric microarrays |
| 05/27/2004 | WO2002079393A3 Dynamic action reference tools |