Patents for C40B 50 - Methods of creating libraries, e.g. combinatorial synthesis (5,219) |
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05/27/2004 | US20040100290 Method of using an array of electrodes for high throughput development and testing of materials |
05/27/2004 | CA2813515A1 T cell receptor display |
05/26/2004 | EP1421216A1 Method for manufacturing hydrogel biochip by using star-like polyethylene glycol derivative having epoxy group |
05/21/2004 | WO2002041179A3 Method for generating a database of molecular fragments |
05/20/2004 | US20040094407 Spatially addressable electrolysis platform and methods of use |
05/19/2004 | EP1419272A1 Method and apparatus for three label microarrays |
05/18/2004 | US6738529 Analysis of chemical data from images |
05/18/2004 | US6737236 Derivatizing oligonucleotides and proteins using cycloaddition reactions including diels-alder reaction or 1,3-dipolar cycloaddition reactions |
05/13/2004 | WO2003093785A3 Biochips with surfaces coated with polysaccharide based hydrogels |
05/13/2004 | WO2003003014A9 Methods and compositions for determining the purity of and purifying chemically synthesized nucleic acids |
05/13/2004 | US20040092736 Collections of compounds |
05/13/2004 | US20040092003 Heat resistance, stability, porosity; support for solid phase synthesis |
05/12/2004 | EP1418004A2 Method for producing a microtiter plate |
05/11/2004 | US6733755 Ligand for vascular endothelial growth factor receptor |
05/06/2004 | US20040087540 Combinatorial library synthesis and pharmaceutically active compounds produced thereby |
05/06/2004 | US20040087009 Array substrates having protective layer |
05/06/2004 | US20040087008 Composite flexible array substrate having flexible support |
05/06/2004 | US20040086869 Multi-array apparatus comprising flexible substrates for diagnostic screening of polynucleotide sequences |
05/06/2004 | EP1415715A1 Device having multiple molecular arrays |
05/06/2004 | EP1415710A1 Composite flexible array substrate |
05/06/2004 | EP1415709A1 Array substrates having protective layer |
05/05/2004 | CN1148580C Cobalamin assay nd reagent kit |
05/05/2004 | CN1148456C Process for preparing peptide nucleic acid probe using polymeric photoacid generator |
04/29/2004 | US20040081974 Method and equipment to monitor nucleic acid hybridization on a dna chip using four-dimensional parameters |
04/29/2004 | US20040081966 Chemical array linking layers |
04/28/2004 | EP1413353A1 Chemical array linking layers |
04/28/2004 | EP1413352A1 Linking to chemical array assemblies with metal layers |
04/28/2004 | EP1412752A1 Methods and compositions for determining the purity of and purifying chemically synthesized nucleic acids |
04/28/2004 | EP1412530A2 Ratio-based oligonucleotide probe selection |
04/28/2004 | EP1412519A2 Configurable dynamic three dimensional array |
04/28/2004 | EP1159064B1 Method for photolytically deprotecting immobilized nucleoside derivatives, especially in the production of dna chips |
04/24/2004 | WO2004038042A1 A 4-dimensional method and equipment of detecting nucleic acid hybrid pair on the gene chip |
04/24/2004 | CA2429101A1 Method and equipment to monitor nucleic acid hybridization on a dna chip using four-dimensional parameters |
04/22/2004 | WO2004016349A3 Method and device for the intermolecular transport of bond cleavage activation energy through space |
04/22/2004 | US20040077826 Randomly generated glycopeptide combinatorial libraries |
04/22/2004 | US20040077006 Methods for manufacturing arrays |
04/22/2004 | US20040076964 Methods for in situ generation of nucleic acid arrays |
04/22/2004 | US20040076963 Contacting the functionalized front surface of a metal substrate with linker molecules each having a group which binds to the surface (e.g., an alkoxysilane) and contacting the surface with probes to bind them to the front surface |
04/21/2004 | EP1117678B1 Solid phase synthesis, whereby the solid phase consists of two different substrates |
04/15/2004 | WO2004031366A2 Manufacturing method and readout system for biopolymer arrays |
04/15/2004 | WO2003083063A3 Common ligand mimics: naphtoates |
04/15/2004 | US20040072831 Reverse-turn mimetics and method relating thereto |
04/15/2004 | US20040072364 Method for high-speed dot array dispensing |
04/15/2004 | US20040071893 Process for applying material layers to shaped bodies |
04/15/2004 | US20040071888 For the rapid formation of liquid samples and thin films therefrom, as well as to the rapid screening of these films to identify those having desirable properties |
04/15/2004 | DE10246740A1 Catalyst composition, useful for metal-catalyzed reactions e.g. asymmetric hydrogenation, comprises protein and interacting catalytic unit that includes a transition metal |
04/08/2004 | WO2004029586A1 Microarray with hydrophobic barriers |
04/08/2004 | WO2003020978B1 Method for manufacturing hydrogel biochip by using star-like polyethylene glycol derivative having epoxy group |
04/07/2004 | EP1405666A2 Substrate for methods to determine analytes and methods to manufacture such substrates |
04/07/2004 | EP1404695A2 Universal supports for oligonucleotide synthesis |
04/07/2004 | EP1404631A1 Method of functionalising solid supports |
04/01/2004 | US20040063196 Microfluidic apparatus for dielectric and optical manipulation of suspended particles, such as, proteins, DNA and cells |
04/01/2004 | US20040063098 Peptide or nucleic acid display; surface hydroxyl number by hydrolysis |
04/01/2004 | US20040062941 Mixture of porous polymer and solid phase support; fine particle sizes; anchoring organic compounds |
03/31/2004 | EP1401569A2 Device for simultaneous multiple and high parallel synthesis |
03/30/2004 | US6713260 Methods of identifying compounds that bind to target species under isothermal denaturing conditions |
03/30/2004 | US6713023 Apparatus for use in monitoring activity associated with the biosynthesis of biopolymers |
03/25/2004 | WO2003078045A3 Microcapillary hybridization chamber |
03/25/2004 | US20040058391 Microarray comprising layered frameworks for use in parallel synthesis of libraries of peptides, oligonucleotides and general organic compounds; drug screening |
03/23/2004 | US6711046 Programmable optical array |
03/23/2004 | US6709824 Screening sample for catalyst; generate library of catalyst, screen library, recover catalyst |
03/18/2004 | WO2004022578A2 Methods, compositions and libraries pertaining pna dimer and pna oligomer synthesis |
03/18/2004 | WO2003078583A3 Optimization of crossover points for directed evolution |
03/18/2004 | WO2003052053A3 Nucleoside libraries and compounds by mcc combinatorial strategies on solid support |
03/18/2004 | WO2003008927A3 Methods and substrates for monitoring binding to a solid phase using proximity based signal generation assays |
03/18/2004 | US20040053354 Methods for optically immobilizing very small objects and their use |
03/18/2004 | CA2495895A1 Methods, compositions and libraries pertaining pna dimer and pna oligomer synthesis |
03/17/2004 | EP1397216A2 Method for parallel synthesis and transfer of molecules to a substrate |
03/17/2004 | CN1483083A Process for producing hydrogel biochip by using epoxy-contained radial polyethylene glycol derivative |
03/16/2004 | US6706244 Apparatus and methods for evaluating the quality of a combinatorial library of compounds |
03/11/2004 | US20040048907 Amines that inhibit a mammalian anandamide transporter, and methods of use thereof |
03/11/2004 | DE10237704A1 Verfahren und Vorrichtung zum intermolekularen Transfer von Aktivierungsenergie zur Bindungsspaltung durch den Raum Method and apparatus for intermolecular transfer of activation energy to the bond cleavage through the space |
03/09/2004 | US6704104 Multi-wavelength array reader for biological assay |
03/04/2004 | WO2004018500A1 Coded nucleic acid carriers |
03/04/2004 | US20040043494 Apparatus for studying arrays |
03/04/2004 | CA2496483A1 Coded nucleic acid carriers |
03/03/2004 | EP1392868A1 Method for the synthesis of dna sequences |
03/02/2004 | US6699843 Method for treatment of tumors using nucleic acid ligands to PDGF |
02/26/2004 | WO2004016349A2 Method and device for the intermolecular transport of bond cleavage activation energy through space |
02/26/2004 | US20040038309 Method and device for nonsynthetic deconvolution |
02/26/2004 | US20040035690 For parallel synthesis and assay of biopolymers using light-directed generation of photo-generated reagents on microarray biochips |
02/25/2004 | EP1390741A1 Structure-based construction of human antibody library |
02/25/2004 | EP1390732A1 Overlying electrode for electrochemical microarrays |
02/19/2004 | WO2004015133A2 Combinatorial synthesis system |
02/19/2004 | WO2003004147A8 Compound libraries |
02/12/2004 | WO2004012856A1 Hybrid chip for the miniaturization of chemical, biomedical, and biological processes and method of application |
02/12/2004 | WO2003066212A3 Microarray synthesis instrument and method |
02/12/2004 | WO2003014325A3 Protein design automation for protein libraries |
02/12/2004 | US20040029259 Method and system for the detection of cardiac risk factors |
02/12/2004 | US20040029172 Generation of combinatorial libraries and assessment thereof by deconvolution |
02/12/2004 | US20040029113 Cleaving single-stranded nucleic acid sequences by contacting with a oligonucleotide; restriction endonuclease recognition site; fab fragments |
02/12/2004 | US20040028804 Production of polymeric microarrays |
02/10/2004 | US6690179 High throughput mechanical property testing of materials libraries using capacitance |
02/10/2004 | US6689478 Substrate with a charged surface coated with one or more bilayers of oppositely charged polyelectrolytes. subsequent bilayers of polyelectrolytes must bear alternating opposite charges; the outer layer is aminated |
02/10/2004 | US6689324 Communication system for automatic synthesis apparatus |
02/05/2004 | WO2003064027A3 Correction for illumination non-uniformity during the synthesis of arrays of oligomers |
02/05/2004 | US20040023368 Apparatus for light controlled parallel synthesis of molecular sequence arrays on solid surfaces |
02/05/2004 | US20040023302 Method and apparatus for screening combinatorial libraries of semiconducting properties |
02/05/2004 | US20040023247 Using fourier transformed infrared imaging to analyze surface properties of solid supports; diagnostic tools for medicinal drug screening and discovery |
02/05/2004 | US20040023224 Maintaining scale factor in an instrument for reading a biopolymer array |