Patents
Patents for C40B 50 - Methods of creating libraries, e.g. combinatorial synthesis (5,219)
02/2004
02/05/2004DE10329928A1 Verfahren zur Aufbereitung von Biochips und Biochip A process for the preparation of biochips and biochip
02/04/2004EP1385821A2 Novel anti-adhesive compounds and uses thereof
01/2004
01/29/2004US20040018614 Biochip preparation method
01/29/2004US20040018498 Peptide and nucleic acid arrays; used in gene expression analysis, drug screening, nucleic acid sequencing, mutation analysis, and the like
01/28/2004EP1384999A1 Bacteriotoxin adsorbents and method of screening the same
01/28/2004EP1384504A2 Methods for producing ligand arrays
01/28/2004EP1383793A2 Insulin and igf-1 receptor agonists and antagonists
01/28/2004EP1383598A2 Method for conducting solid phase synthesis of molecule libraries using combinatorial sealing matrices
01/27/2004US6684161 Combinatorial experiment design method and system
01/27/2004US6683446 Analysis apparatus comprising electrodes and power sources, used for electrodeposition, testing or combinational chemistry; redox systems
01/22/2004WO2004007710A1 Solid support having electrostatic layer and use thereof
01/21/2004EP1382386A2 Novel oligonucleotide arrays and their use for sorting, isolating, sequencing, and manipulating nucleic acids
01/21/2004EP1381857A2 Method and system for planning, performing, and assessing high-throughput screening of multicomponent chemical compositions and solid forms of compounds
01/15/2004US20040009506 Methods and compositions for detection and quantitation of nucleic acid analytes
01/15/2004US20040009487 Comprises applying a blocking reagent to the microarray, the blocking reagent comprises modified nucleotide bases, preferably LNA (Locked Nucleic Acid-modified bicyclic monomeric units with a 2'-O-4'-C methylene bridge)
01/14/2004EP1379329A2 A continuous process for the production of combinatorial libraries of materials
01/13/2004US6678619 Method, system, and computer program product for encoding and building products of a virtual combinatorial library
01/08/2004WO2002044398A3 Universal supports for oligonucleotide synthesis
01/06/2004US6673544 Method for the light-controlled synthesis of biochips
01/02/2004EP1372852A1 Multi-well apparatus
01/02/2004EP1372849A2 Device for automatically dispensing microscopic amounts of liquid
01/02/2004EP1372841A2 Method for producing a plurality of identical copies of a two-dimensional test array of probe molecules
01/01/2004US20040002103 Synthetic ligation reassembly in directed evolution
01/01/2004US20040002085 Apparatus, systems and method for assaying biological materials using an annular format
01/01/2004US20040002078 Arrays
01/01/2004US20040002057 Cloning vectors and methods for producing a library of DNA molecules capable of expressing a fusion polypeptide on the surface of a filamentous phage particle
12/2003
12/31/2003WO2003065038A3 Apparatus for synthesis or arrays of dna probes using micromirrors, prism and k aleidoscopic element
12/31/2003WO2003057858A3 Nucleic acid hybridization-based biosensing devices and methods utilizing intelligently-designed oligonucleotide probe sets
12/31/2003WO2002087769A3 Method for parallel synthesis and transfer of molecules to a substrate
12/30/2003US6670298 Providing different, asymmetric first and second metal-binding ligands to first and second regions of substrate, delivering first metal ion to first region and second metal ion to second region, forming first and second metal-ligand compounds
12/24/2003WO2003106413A2 Process for the preparation of oxazolidinones and method of use thereof
12/24/2003WO2003069319A3 Automated macromolecular crystallization screening
12/24/2003CA2464109A1 Process for the preparation of oxazolidinones and method of use thereof
12/23/2003US6667394 Printing oligonucleotide arrays
12/18/2003US20030232381 Fiber array and methods for using and making same
12/18/2003US20030232343 Test elements bound to a support introduced into a chamber, each test elment containing reaction and detection domains, a fluid reactive with reaction domains is introduced, analyzing locations fluid has not interacted with reaction domain
12/18/2003US20030232140 Applying to a support surface a biopolymers or precursors of the biopolymers, removing support and positioning reagent for conducting synthesis into flow chamber, removing liquid reagent and then support, repeating above steps
12/18/2003US20030232123 Manufacture of arrays with reduced error impact
12/17/2003EP1109805B1 Inhibitors of bacterial nad synthetase
12/16/2003US6664057 Hybridization of probe; diagnosis of breast cancer
12/16/2003US6664051 Fixation of nucleotide derivatives to solid carrier
12/16/2003US6663832 Oligonucleotide synthesizer
12/11/2003WO2003102231A1 Method for parallelly sequencing a nucleic acid mixture by using a continuous flow system
12/11/2003WO2003076940A3 Acyl fluoride activation of carboxysilyl-coated glass substrates
12/11/2003WO2003029481A3 Detection of dna hybridization on surfaces
12/11/2003WO2003020902A3 Methods for blocking nonspecific hybridizations of nucleic acid sequences
12/11/2003WO1999065855A3 Combinatorial libraries of geminally substituted amines
12/11/2003US20030228597 Identification of genetic targets for modulation by oligonucleotides and generation of oligonucleotides for gene modulation
12/11/2003CA2487534A1 Method for parallelly sequencing a nucleic acid mixture by using a continuous flow system
12/10/2003EP1369496A2 Method of making random array of microspheres using enzyme digestion
12/10/2003EP1068216B1 Libraries of oligomers labelled with different tags
12/10/2003CN1460723A Method for preparing biomolecule chip flat-plate with hydrophilic and lipophilic area
12/09/2003US6660479 Process for preparing peptide nucleic acid probe using polymeric photoacid generator
12/04/2003WO2003090605A3 Method and system for the detection of cardiac risk factors
12/04/2003WO2003026590A3 Biological control of nanoparticles
12/04/2003WO2001072771A3 Insulin and igf-1 receptor agonists and antagonists
12/04/2003US20030224361 Method of making random array of microspheres using enzyme digestion
12/04/2003US20030223059 Multi-wavelength array reader for biological assay
11/2003
11/27/2003WO2003097573A1 Amines that inhibit a mammalian anandamide transporter, and methods of use thereof
11/27/2003WO2002072020A3 Novel anti-adhesive compounds and uses thereof
11/27/2003US20030219906 Formation of combinatorial arrays of materials using solution-based methodologies
11/27/2003US20030219196 Microarray system and method of use thereof
11/27/2003US20030218130 Biochips with surfaces coated with polysaccharide-based hydrogels
11/26/2003EP1364702A2 Process for producing array plate for biomolecules having hydrophilic and hydrophobic regions
11/26/2003EP1364213A2 Screening under isothermal denaturing conditions
11/26/2003CN1459022A Nanoscale molecular matrix arrayer
11/25/2003US6653468 Universal support media for synthesis of oligomeric compounds
11/25/2003US6653068 Generation of specific binding partners binding to (poly)peptides encoded by genomic DNA fragments or ESTs
11/20/2003WO2003050237A3 Triazine library with linkers
11/20/2003WO2003048768A3 Protein arrays for allelic variants and uses thereof
11/20/2003US20030215876 Solid phase synthesis with benzylidene linker attaching compound on glass slide; microarrays; drug screening
11/18/2003US6650411 System, method, and product for pixel clocking in scanning of biological materials
11/18/2003US6649662 Methods for optimizing fischer-tropsch synthesis of hydrocarbons in the distillate fuel and/or lube base oil ranges
11/18/2003US6649404 Detecting binding between a immobilized and mobile chemical species (oligonucleotides); signals; use in diagnosis and gene/drug discovery
11/18/2003US6649348 Methods for manufacturing arrays
11/13/2003WO2003093785A2 Biochips with surfaces coated with polysaccharide based hydrogels
11/13/2003WO2003093286A1 Disaccharides for drug discovery
11/13/2003WO2003092892A1 Device for protein crystallisation
11/13/2003WO2003092881A1 Method for producing patterns of physical, chemical or biochemical structures on carriers
11/13/2003WO2003040391A3 Method for producing and identifying soluble protein domains
11/13/2003US20030211539 Apparatus for automated simultaneous chemical synthesis and optional purification of oligonucleotide and/or peptides on solid supports
11/12/2003EP1361285A2 Protein kinase peptide substrate determination using peptide libraries
11/06/2003WO2003090605A2 Method and system for the detection of cardiac risk factors
11/06/2003CA2523626A1 Method and system for the detection of cardiac risk factors
11/05/2003EP1359422A2 Microarray with structured and unstructured probes
11/05/2003EP1359136A2 Polymeric resin compounds and their preparation
11/04/2003US6643015 Consistent sampling of emission signals regardless of scanning direction
11/04/2003US6642014 Enzyme activity screen with direct substrate replacement
10/2003
10/30/2003WO2002087754A3 Method for conducting solid phase synthesis of molecule libraries using combinatorial sealing matrices
10/30/2003US20030203415 Comprises polypeptide for, diagnosis, detection and treatment of cancer
10/30/2003US20030203369 Apparatus and method for determining a signal produced by a micro array device by comparing a signal produced by an unstructured probe to a second signal produced by a structured probe
10/30/2003CA2830864A1 Methods of creating modified promoters resulting in varying levels of gene expression
10/29/2003CN1452631A Computer based method for identifying conserved invariant peptide motifs
10/23/2003WO2003087391A2 Hydrophobic zone device
10/23/2003WO2003087166A2 Photoactivatable silane compounds and methods for their synthesis and use
10/23/2003WO2003086630A1 Microfabricated two-pin system for biomolecule crystallization
10/23/2003WO2003086612A1 Method of producing dynamic combinatorial libraries
10/23/2003WO2001068805A3 Human olfactory receptors and genes encoding same
10/23/2003US20030198999 Apparatus and method for synthesizing combinatorial libraries
10/23/2003US20030198988 Optimization of crossover points for directed evolution
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