Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892) |
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01/11/1984 | EP0097805A2 Nucleoside phosphite compounds |
01/04/1984 | EP0097373A2 Modified labeled nucleotides and polynucleotides and methods of preparing, utilizing and detecting same |
01/03/1984 | CA1159823A1 Alkyl substituted fluorescent compounds and conjugates |
12/21/1983 | EP0096491A2 Eukaryotic metallothionein promoter system |
12/20/1983 | CA1159052A1 Process for making oligonucleotides |
12/08/1983 | WO1983004311A1 Process for preparing fucose antigen and antibody for distinguishing it, measurement of tumor-associated sugar chain utilizing the same, and kit for the measurement |
12/07/1983 | EP0095947A2 Partition proficiency encoded DNA and plasmids incorporating the same for transforming gram-positive organisms |
12/07/1983 | EP0095702A1 Microbially prepared interferon alpha2(Arg), DNA sequence coding for said interferon, microorganisms containing this genetic information and process for their production |
12/07/1983 | EP0095665A1 Labelled conjugates of ethosuximide, ethosuximide immunogens, antibodies thereto, immunoassay method employing the antibodies and reagent means, test kit and test device for the immunoassay method |
12/07/1983 | EP0095639A2 Propranolol immunogens, antibodies thereto, test device and compounds for propranolol immuno assay |
12/06/1983 | US4419509 Process for de-cyanoethylating blocked nucleotides |
11/30/1983 | EP0095452A2 Preparation of DNA sequences and DNA recombinant molecules coding for the cholera toxine units A and B, the products obtained and compositions containing the unit(s) obtained |
11/30/1983 | EP0095361A1 Cloning vectors for expression of exogenous protein |
11/30/1983 | EP0095351A2 A precursor of a C-terminal amidated peptide and production thereof |
11/30/1983 | EP0095350A2 A method of producing human gamma-interferon-like polipeptide |
11/24/1983 | WO1983004053A1 The manufacture and expression of large structural genes |
11/24/1983 | WO1983004030A1 The manufacture and expression of genes for urogastrone and polypeptide analogs thereof |
11/24/1983 | WO1983004029A1 The manufacture and expression of structural genes |
11/24/1983 | WO1983004028A1 The manufacture and expression of genes for calcitonin and polypeptide analogs thereof |
11/24/1983 | WO1983003971A1 Hybrid proteins |
11/23/1983 | EP0094797A2 Novel cloning vehicles for polypeptide expression in microbial hosts |
11/23/1983 | EP0094428A1 Control of dna sequence transcription. |
11/22/1983 | US4417046 Adding solvent ethers to precipitate the polynucleotide while the coupler remains in solution |
11/22/1983 | US4416994 Plasmid pEL7 and related cloning vectors for use in streptomyces and related organisms |
11/22/1983 | US4416988 Detection and isolation of enkephalin mRNA using a synthetic oligodeoxynucleotide |
11/22/1983 | CA1157406A1 Purification of nucleotide sequences suitable for expression in bacteria |
11/15/1983 | US4415732 Phosphoramidite compounds and processes |
11/01/1983 | CA1156145A1 Pharmaceutical composition comprising modified polyriboinosinic-polyribocytidylic acid, for induction of interferon in primates |
10/27/1983 | WO1983003623A1 CODING DNA FRAGMENTS FOR POLYPEPTIDES CONTAINING AT LEAST ONE ANTIGENIC DETERMINANT OF THE PAPILLOMAVIRUS PARTICULARLY OF THE 1a HPV TYPE AND CORRESPONDING POLYPEPTIDES |
10/26/1983 | EP0092456A1 DNA fragments encoding for polypeptides containing at least an antigenic determinant of Papilloma viruses, notably of the HPV 1A-type, and corresponding polypeptides |
10/26/1983 | EP0092182A2 Preparation of functional human urokinase polypeptides |
10/19/1983 | EP0091723A2 Vector system |
10/19/1983 | EP0091527A2 DNA sequences, recombinant DNA molecules and processes for producing human serum albumin-like polypeptides |
10/18/1983 | CA1155442A1 Nucleosidic coupling agent and methods |
10/05/1983 | EP0090789A1 Chemical DNA synthesis |
10/05/1983 | EP0090505A2 Human antithrombin III, DNA sequences therefor, expression vehicles and cloning vectors containing such sequences and cell cultures transformed thereby, a process for expressing human antithrombin III, and pharmaceutical compositions comprising it |
09/28/1983 | EP0089692A2 Alpha-interferon Gx-1 |
09/28/1983 | EP0089666A2 Human growth hormone variants |
09/21/1983 | EP0089233A2 Plasmid pSAN 81 and a process for its extraction from a cell culture |
09/21/1983 | EP0088994A2 Hybrid DNA, binding composition prepared thereby and processes therefor |
09/15/1983 | WO1983003098A1 Polynucleotide synthesis |
09/14/1983 | EP0088632A2 Expression, processing and secretion of heterologous protein by yeast |
09/14/1983 | EP0088622A2 Animal interferons, processes involved in their production, compositions containing them, DNA sequences coding therefor and expression vehicles containing such sequences and cells transformed thereby |
09/14/1983 | EP0088195A2 Messenger RNA, production and use thereof |
09/13/1983 | US4404368 Using dioxane solvent; storage stability; polynucleotides; supports; genetic engineering |
09/13/1983 | US4404109 Aqueous micro-emulsions of organic substances |
09/07/1983 | EP0087735A2 Recombinant DNA, microorganism transformed therewith and their use |
08/30/1983 | US4401796 Phosphorylation of a nucleoside to obtain a monotriazolide; reacting with a modified resin support; hydrolysis |
08/24/1983 | EP0086649A2 Molecular cloning and characterization of the gene sequence coding for porcine relaxin |
08/24/1983 | EP0086548A2 A method of cleaving double stranded DNA |
08/23/1983 | US4400375 Tobramycin-double stranded RNA complex suitable for inducing interferon |
08/23/1983 | CA1152491A1 Flavin adenine dinucleotide-labeled protein and polypeptide conjugates |
08/23/1983 | CA1152490A1 Beta-galactosyl-umbelliferone-labeled protein and polypeptide conjugates |
08/17/1983 | EP0086139A2 Expression vectors for catechol-2,3-dioxygenase, enzymes obtained and their uses |
08/10/1983 | EP0085548A2 Cloning vectors |
08/04/1983 | WO1983002616A1 COMPOSITION AND METHOD FOR FORMING A<5'>p<5'>p<n3'>p (AppNp) |
08/03/1983 | EP0084796A2 HLA typing method and cDNA probes used therein |
07/19/1983 | US4394487 Adsorbent for the affinity-specific separation of macromolecular materials |
07/19/1983 | US4394443 Method for cloning genes |
07/19/1983 | CA1150169A1 Broad host range small plasmid rings as cloning vehicles |
07/12/1983 | US4393137 Genetic engineering |
07/12/1983 | US4393010 Nucleosidic phosphorylating agent and methods |
07/07/1983 | WO1983002277A1 Dna fragments marked at least at one of the ends thereof by modified ribonucleotides recognizable by related molecules and method for analyzing such dna fragments |
07/07/1983 | WO1983002276A1 Modified adenosine 5'-triphosphoric acid and method for dosing biological substances capable of fixing degradation products of adenosine 5'-triphosphoric acid |
07/06/1983 | EP0083286A2 Modified vaccinia virus and methods for making and using the same |
07/06/1983 | EP0083069A2 Recombinant plasmid containing human interferon-beta gene |
06/29/1983 | EP0082485A2 Novel vector plasmids |
06/21/1983 | US4389396 Immunostimulating preparations based on ribosomal RNA's and a process for the preparation of the RNA's |
06/21/1983 | US4389395 Low molecular weight complex of polyriboinosinic-polyribocytidylic acid and method of inducing interferon |
06/15/1983 | EP0081099A2 Capped oligonucleotide anti-viral agents |
06/14/1983 | US4388306 Pharmaceutical composition comprising modified polyriboinosinic-polyribocytidylic acid, for induction of interferon in primates |
06/08/1983 | EP0080848A2 Stabilizing & selecting cells |
06/01/1983 | EP0080357A1 Composition for treating tumor cells |
05/26/1983 | WO1983001783A1 Control of dna sequence transcription |
05/25/1983 | EP0079739A2 Albumin-based nucleotides, their replication and use, and plasmids for use therein |
05/24/1983 | US4385112 Cultures, pseudomonas, quantitative nucleoside assay, making nucleoside-5-carboxylic acids |
05/11/1983 | EP0078537A2 Plasmid pHM 1519 |
05/10/1983 | US4383033 Radioiodine labeling during protein synthesis |
05/10/1983 | CA1146169A1 Pyridocarbazoles oligomers and therapeutic use thereof |
05/04/1983 | EP0078154A2 Plasmids and cells for heterologous expression of metallothioneins and processes for producing and using the metallothionein |
04/28/1983 | WO1983001451A1 Oligonucleotide therapeutic agent and methods of making same |
04/27/1983 | EP0077670A2 Human immune interferon |
04/27/1983 | EP0077650A2 Cloning vectors |
04/27/1983 | EP0077569A2 DNA gene |
04/27/1983 | EP0077557A2 Process for the production of plasmid pAC 1 |
04/27/1983 | EP0077548A2 Plasmid |
04/20/1983 | EP0077109A2 DNA molecules comprising the genes for preprochymosin and its maturation forms, and microorganisms transformed thereby |
04/12/1983 | US4379843 Immobilization of polynucleotides and polypeptides with tritylated polysaccharides |
04/06/1983 | EP0075885A1 Microorganisms for the microbiol degradation of obnoxious organic wastes into innocuous materials |
03/30/1983 | EP0075444A2 Methods and products for facile microbial expression of DNA sequences |
03/30/1983 | EP0075395A2 Products displaying the antigenicity of hepatitis B virus E antigens and methods of producing those antigens |
03/30/1983 | EP0075392A1 Process for de-cyanoethylating blocked nucleotides |
03/30/1983 | EP0075262A2 Process for the preparation of 5-ribo nucleotides |
03/29/1983 | US4378458 A 3-furyl phosphate derivative having a nucleotide base substituent in the 2 position |
03/29/1983 | US4378352 (2'-5')Oligo-isoadenylate pharmaceutical compositions and method of use |
03/23/1983 | EP0074808A2 Recombinant method and materials |
03/16/1983 | EP0073826A1 Rapid solid phase synthesis of oligonucleotides using phosphorus oxychloride activation |
03/15/1983 | US4376821 Production of human IFN-gamma (immune) interferon |
03/09/1983 | EP0073657A1 Preparation of hepatitis B surface antigen in yeast |
03/09/1983 | EP0073656A2 Preparation of polypeptides in vertebrate cell culture |