Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892) |
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08/22/2000 | CA2160784C Ligase chain reaction with endonuclease iv correction and contamination control |
08/22/2000 | CA1341088C Inhibition of htlv-iii by exogenous oligonucleotides |
08/17/2000 | WO2000047777A1 Protection probes |
08/17/2000 | WO2000047775A1 Selection of proteins using rna-protein fusions |
08/17/2000 | WO2000047601A1 Shortened-chain polynucleotides and process for the preparation thereof |
08/17/2000 | WO2000047599A1 Novel nucleosides and oligonucleotide analogues |
08/17/2000 | WO2000047598A1 Method and apparatus for compound library preparation using optical modulator |
08/17/2000 | WO2000047593A1 Compounds, processes and intermediates for synthesis of mixed backbone oligomeric compounds |
08/17/2000 | CA2359674A1 Chain-shortened polynucleotide and method for preparation thereof |
08/16/2000 | EP1028124A2 Improved process for the synthesis of oligomeric compounds |
08/16/2000 | EP1027437A1 Wnt-1 induced secreted polypeptides: wisp-1, -2 and -3 |
08/16/2000 | EP1027366A2 Synthesis of polynucleotides having random sequences |
08/16/2000 | EP1027364A2 Pyrimidine derivatives for labeled binding partners |
08/16/2000 | EP1027160A1 Pressure-enhanced extraction and purification |
08/16/2000 | EP1027145A1 Apparatuses and methods for isolating nucleic acid |
08/16/2000 | EP1027121A1 Improved liquid chromatographic media for polynucleotide separation |
08/16/2000 | CN1263560A Methods for diagnosis and treating cancers, and methods for identifying pathogenic markers in sample of normal cells |
08/16/2000 | CN1055478C Method of fast recovery of DNA segments by glass screen column |
08/15/2000 | US6103891 Efficient process by reacting a nucleotide or oligonucleotide having a phosphate or phosphite linkage with a (halophenoxy)dihalophosphorane, contacting product with a secondary amine to produce a phosphoramidite linkage |
08/15/2000 | US6103509 Modified glucose dehydrogenase |
08/15/2000 | US6103476 Detectably labeled, dual conformation oligonucleotide probes, assays and kits |
08/15/2000 | CA2202280C Sugar modified nucleosides and their use for synthesis of oligonucleotides |
08/10/2000 | WO2000046231A1 Method for deprotecting oligonucleotides |
08/10/2000 | WO2000045957A1 System, method and computer program product for automated fluid or gas delivery |
08/10/2000 | WO2000033084A3 Arrays of organic compounds attached to surfaces |
08/10/2000 | WO2000026368A3 Therapeutic antiangiogenic endostatin compositions |
08/10/2000 | DE19903507A1 Verfahren zur Herstellung endotoxinfreier oder an Endotoxin abgereicherter Nukleinsäuren und deren Verwendung Process for the preparation endotoxin or endotoxin-depleted nucleic acids and their use |
08/09/2000 | EP1026259A1 Dna chip and its preparation |
08/09/2000 | EP1026253A2 Expression of exogenous polynucleotide sequences in a vertebrate |
08/09/2000 | EP1025902A2 Apparatus and method for polymer synthesis using arrays |
08/09/2000 | EP1025263A2 Labelling of polymers and sequencing of nucleic acids |
08/09/2000 | EP1025244A2 NOVEL MODIFIED MSP-1 NUCLEIC ACID SEQUENCES AND METHODS FOR INCREASING mRNA LEVELS AND PROTEIN EXPRESSION IN CELL SYSTEMS |
08/09/2000 | EP1025233A2 Novel modified nucleic acid sequences and methods for increasing mrna levels and protein expression in cell systems |
08/09/2000 | EP1025115A1 Novel nucleoside or nucleotide fluorescent conjugates, preparation method and uses |
08/09/2000 | EP1025113A1 Improved process for performing polynucleotide separations |
08/09/2000 | EP1024821A1 Novel prokaryotic polynucleotides, polypeptides and their uses |
08/09/2000 | EP0863912B1 Novel polymer supports for nucleic acid synthesis |
08/09/2000 | EP0690914B1 Allergenic protein and peptides from house dust mite and uses therefor |
08/09/2000 | EP0640133B1 Recombinant dna molecules encoding aminopeptidase enzymes and their use in the preparation of vaccines against helminth infections |
08/08/2000 | US6100390 Nucleotide sequences coding nematode protein; for the prevention of nematode infection of animals |
08/08/2000 | US6100040 Methods and compositions for detection of specific nucleotide sequences |
08/08/2000 | US6099803 Devices containing active electrodes especially adapted for electrophoretic transport of nucleic acids, their hybridization and analysis |
08/08/2000 | CA1341073C Vectors and methods for expression of human protein c activity |
08/03/2000 | WO2000044759A1 Method for producing endotoxin-free nucleic acids and the use thereof |
08/03/2000 | WO2000044491A2 Centrifuging apparatus and method for separation of liquid phases and organic synthesis |
08/03/2000 | WO2000017320A3 Methods and reagents for inactivating ribonucleases |
08/03/2000 | WO2000009689A9 A single gene encoding aortic-specific and striated-specific muscle cell isoforms, its regulatory sequences and uses thereof |
08/03/2000 | CA2361223A1 Centrifuging apparatus and method for separation of liquid phases and organic synthesis |
08/02/2000 | EP1024198A2 Pseudo-adenoviral vectors for the gene therapy of haemophiliae |
08/02/2000 | EP1024192A2 Clot-specific streptokinase proteins possessing altered plasminogen activation characteristics and a process for the preparation of said proteins |
08/02/2000 | EP1023463A1 Modifying double stranded dna to enhance separations by matched ion polynucleotide chromatography |
08/02/2000 | EP1023460A1 Method of isolating rna |
08/02/2000 | EP1023316A2 Methods and compositions for lipidization of hydrophilic molecules |
08/02/2000 | EP1023313A1 Inhibition of stress activated protein kinase (sapk) pathway and sensitization of cells to cancer therapies |
08/02/2000 | EP1023310A1 Improved synthesis of sulfurized oligonucleotides |
08/02/2000 | EP1023309A2 High surface density covalent immobilization of oligonucleotide monolayers |
08/02/2000 | EP1023308A1 Inhibitors of nucleoside metabolism |
08/02/2000 | EP1023306A1 System and method for performing polynucleotide separations using liquid chromatography |
08/02/2000 | CN1261893A 3'-monophosphorylating oligonucleotides |
08/01/2000 | US6096899 Cylic imidazole compounds having relatively low hydrogen content and relatively high nitrogen content and polymers formed therefrom |
08/01/2000 | US6096881 Sulfur transfer reagents for oligonucleotide synthesis |
08/01/2000 | US6096875 Nucleoside/nucleotide including base, rigid linker, spacer and member of linkage pair or label; for terminators and chain-extenders in sanger-type dna sequencing or polymerase chain reactions |
08/01/2000 | US6096723 4,7-dichlorofluorescein dyes as molecular probes |
08/01/2000 | US6096722 Non-steroidal treatment/prophylaxis |
08/01/2000 | US6096551 Methods for producing antibody libraries using universal or randomized immunoglobulin light chains |
08/01/2000 | US6096527 Nucleic acids encoding protein tryosine kinases |
08/01/2000 | US6096516 cDNAs encoding murine antibody against human plasma apolipoprotein B-100 |
08/01/2000 | US6096515 Nucleotide sequence of polypeptide associated with transcription factor, nuclear factor of activated t cells; hybridization probes; polymerase chain reaction primers;screening for immunomodulators; therapy of related |
08/01/2000 | US6096513 Amino acid sequences; for screening agonists and antagonists; for analgesics |
08/01/2000 | US6096506 Antibodies specific for growth differentiation factor-8 and methods of using same |
08/01/2000 | US6096319 Peptides with amino acid sequences |
08/01/2000 | US6096273 Site-selective modification of nucleic acids with electron transfer moieties and electrodes, for gene probes, medical diagnosis, tissue compatibility evaluations before transplantation, forensics |
08/01/2000 | CA2006322C Recombinant dna molecules, hosts, processes and human somatomedin carrier protein-like polypeptides |
07/27/2000 | WO2000043547A1 Dna mobility modifier |
07/27/2000 | WO2000043515A2 Methods of monitoring hiv drug resistance |
07/27/2000 | WO2000043493A2 Metalloproteinase adam 22 |
07/27/2000 | WO2000017401A3 Method and apparatus for effecting and monitoring nucleic acid amplification |
07/27/2000 | DE19926457A1 Verfahren zur elektrochemischen Detektion von Nukleinsäure-Oligomer-Hybridisierungsereignissen A process for electrochemically detecting nucleic acid oligomer hybridization events |
07/26/2000 | EP1021558A1 Surface-bound, double-stranded dna protein arrays |
07/26/2000 | EP1021549A2 SENSE mRNA THERAPY |
07/26/2000 | EP1021464A1 Cellular receptor for hiv-1 vpr essential for g2/m phase transition of the cell cycle |
07/26/2000 | EP1021201A1 Use of growth differenciation factor-9 (gdf-9) as a contraceptive |
07/26/2000 | EP1021176A1 Cobalt schiff base compounds |
07/26/2000 | EP0836612B1 Novel synthons for stereoselective oligonucleotide synthesis |
07/26/2000 | EP0720615B1 Elongation, amplification and sequence determination using a chimeric oligonucleotide |
07/26/2000 | CN1261105A Human gene pRb-BP125 reacting on anticancer gene coding resultant pRB |
07/25/2000 | US6093811 Oligonucleotide modulation of cell adhesion |
07/25/2000 | US6093560 The polypeptide has ability to induce cell cycle arrest; being activated by oxidant stress not by epidermal growth factor, platelet-derived growth factor (pdgf), tumor necrosis factor-alpha, anisomycin, heat shock, or osmolar stress |
07/25/2000 | US6093559 Producing low binding hydrophobic surfaces by treating with a low HLB number non-ionic surfactant |
07/25/2000 | US6093555 Amido and peptido modified enzymatic nucleic acid molecules |
07/25/2000 | US6093550 Unique associated Kaposi's sarcoma virus sequences and uses thereof |
07/25/2000 | US6093540 Method for diagnosing a disorder characterized by expression of a BAGE tumor rejection antigen precursor |
07/25/2000 | US6093538 Nucleotide sequences of 10 to 100 nucleotides in length for rapid detection of urogenital bacteria linked to disorders |
07/25/2000 | US6093537 Detecting target sequence in sample by mixing with pair of nucleotide sequences, hybridizing, attaching nucleotide sequences together, adding nucleotide sequence specific binding proteins, and detecting binding |
07/25/2000 | US6093393 Methods for preparing and using clonogenic fibroblasts and transfected clonogenic fibroblasts |
07/25/2000 | US6092764 Interface seal for an aircraft |
07/20/2000 | WO2000042217A2 Method for electrochemically detecting nucleic acid-oligomer hybridisation events |
07/20/2000 | WO2000042069A1 Bone stimulating factor |
07/20/2000 | WO2000041731A1 Reverse gene therapy |
07/20/2000 | WO2000024885A3 p53 MORPHOLINO-BASED ANTISENSE |