Patents
Patents for C07D 217 - Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems (11,865)
10/2012
10/02/2012US8278334 Cyclic amine BACE-1 inhibitors having a benzamide substituent
10/02/2012US8278325 Nitrogen-containing heteroaryl compounds and methods of use thereof
09/2012
09/27/2012US20120245163 TRPV1 Antagonists
09/26/2012CN101896462B Process for the resolution of isoquinoline derivatives
09/26/2012CN101808992B 1,1,1-trifluoro-2-hydroxy-3-phenylpropane derivatives
09/26/2012CN101508682B Novel organic electroluminescent compounds and organic electroluminescent device using the same
09/25/2012US8273891 Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, pyrazolopyridines, isothiazolopyridines, and preparation and uses thereof
09/25/2012US8273767 Bicyclic-substituted amines as histamine-3 receptor ligands
09/25/2012US8273766 Tetrahydroisoquinoline compound
09/25/2012US8273733 Tetrahydroisoquinoline sulfonamide derivatives, the preparation thereof, and the use of the same in therapeutics
09/25/2012CA2560071C Lysine based compounds
09/20/2012WO2012124825A1 Sulfonamide compounds having trpm8 antagonistic activity
09/20/2012WO2012124744A1 Nitrogen-containing condensed heterocyclic compound
09/20/2012WO2012124696A1 Guanidine compound
09/20/2012US20120238749 Inhibitors of interleukin-1 beta converting enzyme
09/20/2012CA2830157A1 Guanidine compound
09/20/2012CA2826678A1 Sulfonamide compounds having trpm8 antagonistic activity
09/19/2012EP2498599A1 Analgesic that binds filamin a
09/19/2012CN102675031A Beta-dinaphthyl anthracene and derivative thereof and preparation method
09/18/2012US8269010 3-amino-pyridine derivatives for the treatment of metabolic disorders
09/18/2012US8268885 Entry inhibitors of the HIV virus
09/18/2012US8268842 Fused ring 4-oxopyrimidine derivative
09/18/2012US8268833 Inhibitors of histone deacetylase
09/13/2012WO2012120398A1 Aryl substituted carboxamide derivatives as trpm8 modulators
09/12/2012CN102659676A Process for purifying yuzirine
09/12/2012CN102659675A Synthetic method for 6- bromo-2-methyl sulfonyl-1,2,3,4,-tetrahydroisoquinoline
09/12/2012CN102659674A Process for extracting salsoline from Common Russianthistle Herb
09/12/2012CN102659630A Hydroxamic acid compound and preparation method as well as application thereof
09/11/2012US8263607 1-substituted tetrahydroisoquinoline compound
09/11/2012US8263604 Pyridyl- and pyrimidinyl-substituted pyrrole-, thiophene- and furane-derivatives as kinase inhibitors
09/07/2012WO2012117421A1 Histone deacetylase inhibitors
09/07/2012WO2012080284A3 Substituted 6,6-fused nitrogenous heterocyclic compounds and uses thereof
09/05/2012EP2493571A1 Alkynyl derivatives useful as dpp-1 inhibitors
09/05/2012CN101952254B Isoquinoline modulators of ATP-binding cassette transporters
09/05/2012CN101466683B Inhibitors of AKT (protein kinase B)
09/04/2012US8258302 Method for producing benzazepinone
08/2012
08/30/2012US20120220774 Process for Synthesizing Substituted Isoquinolines
08/29/2012EP2492276A1 Metal complex, polymer, and element obtained using same
08/29/2012EP2491019A1 Methods and compositions for panic disorders
08/29/2012CN101443315B Bicycloheteroaryl compounds as P2X7 modulators and uses thereof
08/28/2012US8252811 Indazoles, benzothiazoles, and benzoisothiazoles, and preparation and uses thereof
08/23/2012WO2012112946A1 Substituted 6,7-dialkoxy-3-isoquinolinol derivatives as inhibitors of phosphodiesterase 10 (pde10a)
08/23/2012WO2012090177A3 Cannabinoid receptor modulators
08/23/2012US20120214837 Substituted 6,7-dialkoxy-3-isoquinolinol derivatives as inhibitors of phosphodiesterase 10 (pde10a)
08/23/2012CA2827724A1 Substituted 6,7-dialkoxy-3-isoquinolinol derivatives as inhibitors of phosphodiesterase 10 (pde10a)
08/22/2012EP2488544A1 Affinity ligands and methods for protein purification
08/22/2012EP2181095B1 Novel bronchodilating alpha, beta-unsaturated isoquinoline amides
08/22/2012CN102643231A Preparation method for isoquinoline alkaloid
08/22/2012CN101268054B Substituted 4-phenyltetrahydroisoquinolines, process for their preparation, pharmaceutical compositions and therapeutic use
08/21/2012US8247560 Trisubstituted 3,4-dihydro-1H-isoquinolin compound, process for its preparation, and its use
08/21/2012US8247413 e.g. N-[2-(3-fluorophenyl)ethyl]-N'-isoquinolin-5-ylurea; opioid receptor inhibitor; analgesic, antiinflammatory agent; inflammatory thermal hyperalgesia, urinary incontinence and bladder overactivity
08/21/2012US8246854 Organic catalyst with enhanced solubility
08/16/2012WO2012109544A1 Novel 1-(1-oxo-1,2,3,4-tetrahydroisoquinolin-7-yl)urea derivatives as n-formyl peptide receptor like-1 (fprl-1) receptor modulators
08/16/2012WO2012108490A1 Isoquinoline amide derivative
08/16/2012US20120208842 Novel 1-(1-OXO-1,2,3,4-TETRAHYDROISOQUINOLIN-7-YL)Urea Derivatives As N-FORMYL Peptide Receptor Like-1 (FPRL-1) Receptor Modulators
08/16/2012CA2827005A1 Novel 1-(1-oxo-1,2,3,4-tetrahydroisoquinolin-7-yl)urea derivatives as n-formyl peptide receptor like-1 (fprl-1) receptor modulators
08/15/2012EP2485728A1 Wnt pathway antagonists
08/14/2012US8242277 Preparation of tetrahydroisoquinolines from dihydroisoquinolines
08/14/2012US8242134 Isoquinolinone derivatives as NK3 antagonists
08/09/2012WO2012105588A1 Tetrahydroisoquinoline derivative
08/09/2012WO2012104659A1 Novel ether linked compounds and improved treatments for cardiac and cardiovascular disease
08/09/2012US20120202847 Novel Tetrahydroisoquinoline Compounds
08/09/2012US20120202800 Dual small molecule inhibitors of cancer and angiogenesis
08/09/2012US20120202795 Substituted pyridones as inhibitors of poly(adp-ribose) polymerase (parp)
08/09/2012CA2828570A1 Tetrahydroisoquinoline derivative
08/08/2012EP1838296B1 Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases
08/08/2012CN102627604A Two types of isoquinoline compounds and application thereof to preparing anti-cancer medicaments
08/08/2012CN102627518A Preparation method of N-nitrosamine
08/08/2012CN101921229B Synthesis method of stepholidine or derivative optical isomer thereof and intermediate thereof
08/07/2012US8236796 Aryl- and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
08/02/2012WO2012101197A1 Substituted 3-heteroaroylamino-propionic acid derivatives and their use as pharmaceuticals
08/02/2012WO2012078593A3 Lysophosphatidic acid receptor antagonists and their use in the treatment fibrosis
08/02/2012CA2822120A1 Substituted 3-heteroaroylamino-propionic acid derivatives and their use as pharmaceuticals
08/01/2012EP1753421B1 Arylsulfonamides and uses as hydroxysteroid dehydrogenase
08/01/2012CN102617557A Compositions and methods for treatment of eye disorders
08/01/2012CN102617464A fused compounds that inhibit vanilloid receptor subtype 1 (vr1) receptor
08/01/2012CN102617456A Electron transporting-injection compound and organic electroluminescent device using the same
07/2012
07/31/2012US8232400 Preparation of 3,4-dihydroisoquinolines in the synthesis of morphinans
07/31/2012US8232399 Chiral ligands, their preparation and uses thereof in asymmetric reactions
07/26/2012WO2012097683A1 Bicyclic inhibitors of alk
07/26/2012US20120190845 Fused compounds that inhibit vanilloid receptor subtype 1 (vr1) receptor
07/26/2012CA2824332A1 Bicyclic inhibitors of alk
07/25/2012CN102603675A Piperazine compound and application thereof
07/25/2012CN102603630A O-aminobenzoic acid sulfonylation derivative as well as preparation method and application thereof
07/25/2012CN102603629A Dihydroisoquinoline compounds and application of dihydroisoquinoline compounds for preparing antibacterial agents for plants
07/25/2012CN102603552A Preparation method of alpha-keto amide
07/25/2012CN102600844A Ni-NiO/gamma-Al2O3 catalyst for preparing pyridine and pyridine byproducts as well as preparation method
07/24/2012US8227611 Process for the preparation of hexahydroisoquinolines from 1,2,3,4-tetrahydroisoquinolines
07/24/2012US8227486 Aryl- and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
07/24/2012US8227480 Indazole derivative having spiro ring structure in side chain
07/24/2012CA2690226C Novel malonic acid sulfonamide derivative and pharmaceutical use thereof
07/24/2012CA2476065C Inhibitors of histone deacetylase
07/18/2012EP2476669A1 Cyanoisoquinoline compounds and methods of use thereof
07/18/2012CN102596978A Metal complex, polymer, and element obtained using same
07/18/2012CN102596321A Alkynyl derivatives useful as dpp-1 inhibitors
07/18/2012CN102584699A Method for manufacturing 3-acetyl-iso-quinoline and its derivatives
07/18/2012CN101747269B Purification method of isoquinoline
07/17/2012CA2643493C 1-naphtholyl tetrahyroisoquinoline derivatives and use thereof as chiral ligands in asymmetric synthesis
07/12/2012WO2012093271A1 A new palladium catalyst, method for its preparation and its use
07/11/2012CN102575155A Novel organic electroluminescent compounds and organic electroluminescent device using the same
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