Patents for C07D 217 - Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems (11,865) |
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07/11/2012 | CN102558173A Compound inhibiting conduction of WNT signal, and composition and application thereof |
07/11/2012 | CN101602725B Synthetic method of hexahydroisoquinoline-1-keto compound |
07/10/2012 | CA2444704C Synthesis and evaluation of phthalimide mimics as anti-angiogenic agents |
07/10/2012 | CA2407675C Combretastatin a-1 phosphate and combretastatin b-1 phosphate prodrugs |
07/05/2012 | WO2012090179A2 Isoquinoline derivatives as cannabinoid receptor modulators |
07/05/2012 | WO2012090177A2 Cannabinoid receptor modulators |
07/05/2012 | US20120172392 Amine-based and amide-based inhibitors of semicarbazide-sensitive amine oxidase (ssao) enzyme activity and vap-1 mediated adhesion useful for treatment of diseases |
07/05/2012 | US20120171119 Pegylated fluorobenzamide analogues, their synthesis and use in diagnostic imaging |
07/04/2012 | EP2471777A1 Novel tetrahydroisoquinoline compounds |
07/04/2012 | CN202289495U 高纯度异喹啉生产的蒸发器 Production of high purity isoquinoline evaporator |
07/04/2012 | CN102532021A Preparation method of 2-alkoxy-3,4-disubstituted isoquinoline-1(2H)-one derivatives |
07/04/2012 | CN102532020A 5, 6, or 7-substituted -3-(hetero) arylisoquinolinamine derivatives and therapeutic use thereof |
07/04/2012 | CN102532019A Method for preparing multi-substituted isoquinoline and analogues thereof |
07/04/2012 | CN102532018A Method for purifying Michellamine C |
07/04/2012 | CN101898982B Npy y5 antagonists |
07/04/2012 | CN101851199B Substituted piperazine N-ethyl sulfonamide derivative and preparation and application thereof |
07/04/2012 | CN101454289B Substituted tetrahydroisoquinoline compounds, their preparation and use in medicaments |
07/03/2012 | US8212040 Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and thereof |
07/03/2012 | CA2671904C Intermediate duration neuromuscular blocking agents and antagonists thereof |
06/28/2012 | WO2012086727A1 Novel substituted isoquinoline derivative |
06/28/2012 | WO2012085003A1 2-hydroxyisoquinoline-1,3(2h,4h)-diones and related compounds useful as hiv replication inhibitors |
06/28/2012 | US20120165322 Rho kinase inhibitors |
06/28/2012 | CA2822787A1 Novel substituted isoquinoline derivative |
06/27/2012 | EP2007729B1 Substituted tetrahydroisoquinoline compounds, their preparation and use in medicaments |
06/27/2012 | EP1389611B1 20-hydroxyeicosatetraenoic acid production inhibitors |
06/27/2012 | CN102516170A Amide derivatives |
06/27/2012 | CN102516169A Method for preparing polysubstituted isoquinoline and heterocyclic pyridine derivants |
06/26/2012 | US8207341 Process or synthesizing substituted isoquinolines |
06/26/2012 | CA2511970C Urea derivatives useful in the treatment of heart failure |
06/21/2012 | WO2012081031A1 Process for preparing tetrabenazine |
06/21/2012 | WO2012080284A2 Substituted 6,6-fused nitrogenous heterocyclic compounds and uses thereof |
06/21/2012 | US20120157454 Isoquinolin-1 (2h) -one derivatives as parp-1 inhibitors |
06/21/2012 | CA2817460A1 Substituted 6,6-fused nitrogenous heterocyclic compounds and uses thereof |
06/20/2012 | EP2464616A1 Organic compound and organic light-emitting device using the same |
06/20/2012 | EP2144881B1 Isoquinolinone derivatives, processes for their preparation and their use in the treatment of chronic obstructive pulmonary disease ( copd ) and asthma |
06/20/2012 | CN102503888A 2-aryl-1,3-isoquinoline diketone anti-tumor compound and synthesis method and application thereof |
06/20/2012 | CN102503887A Method for preparing 1-(N-substituted amino)isoquinoline compounds |
06/20/2012 | CN102503883A Method for selectively preparing isoindoline-1-ketone derivative or isoquinoline-1-ketone derivative |
06/19/2012 | US8202996 Crystalline forms of N-(tert-butoxycarbonyl)-3-methyl-L-valyl-(4R)-4-((7-chloro-4-methoxy-1-isoquinolinyl)oxy)-N- ((1R,2S)-1-((cyclopropylsulfonyl)carbamoyl)-2-vinylcyclopropyl)-L-prolinamide |
06/19/2012 | US8202885 Bridged six-membered ring compounds |
06/14/2012 | WO2012078593A2 Lysophosphatidic acid receptor antagonists and uses thereof |
06/14/2012 | CA2820817A1 Lysophosphatidic acid receptor antagonists and uses thereof |
06/13/2012 | EP2463276A1 Nitrogenous-ring acylguanidine derivative |
06/13/2012 | EP2461683A1 Bicyclic aryl sphingosine 1-phosphate analogs |
06/13/2012 | EP1776119B9 Tetrahydro-naphthalene derivatives as glucocorticoid receptor modulators |
06/13/2012 | EP1618087B1 Antibacterial agents |
06/13/2012 | CN102491945A Method for recovering S-shaped tetrahydroisoquinoline |
06/07/2012 | US20120142727 Nitrogenous-ring acylguanidine derivative |
06/06/2012 | EP2459529A1 Substituted phenoxypropylcycloamine derivatives as histamine-3 (h3) receptor ligands |
06/06/2012 | CN101213187B Isoquinoline derivatives as inhibitors of RHO-kinase |
06/05/2012 | US8193360 Radiolabelled fluorobenzamide analogues, their synthesis and use in diagnostic imaging |
05/31/2012 | WO2012070701A1 Quinoline derivative compound, method for preparing same, and pharmaceutical composition containing same |
05/31/2012 | WO2012069566A1 Synthesis of n-heterocycles by reductive alkylation of cyan derivatives |
05/31/2012 | US20120136002 Protease inhibitors |
05/31/2012 | US20120135984 Dual-action inhbitors and methods of using same |
05/31/2012 | US20120135968 Tetracycline Compounds |
05/30/2012 | CN102482220A 含氮环酰基胍衍生物 Acyl derivatives of nitrogen-containing cyclic guanidine |
05/30/2012 | CN102477001A Benzamide histone deacetylase inhibitor |
05/29/2012 | US8188115 5-HT7 receptor antagonists |
05/29/2012 | CA2318731C Ppar-gamma modulators |
05/24/2012 | WO2012067963A1 Nampt inhibitors |
05/24/2012 | US20120129818 Compositions and Methods for Treatment of Cardiovascular Disease |
05/24/2012 | CA2817093A1 Nampt inhibitors |
05/23/2012 | EP2453895A1 (+) - morphinans as antagonists of toll-like receptor 9 and therapeutic uses thereof |
05/23/2012 | CN102471276A 新型四氢异喹啉化合物 Novel tetrahydroisoquinoline compounds |
05/23/2012 | CN102471275A SMAC mimetic |
05/23/2012 | CN102471261A 新型二芳基胺化合物、以及抗老化剂、聚合物组合物、橡胶交联物及其成型品、以及二芳基胺化合物的制备方法 Novel diaryl amine compounds, and anti-aging agent, a polymer composition, the rubber composition and the crosslinked molded article, and a method for preparing a diaryl amine compound |
05/23/2012 | CN102464615A 芳基异喹啉类衍生物及其药物组合物、制备方法和用途 Aryl isoquinoline derivatives and pharmaceutical compositions thereof, preparation and use |
05/23/2012 | CN102040556B Optical isomers of indene quinazoline, preparation method and medicinal application thereof |
05/23/2012 | CN101490006B Biarylcarboxyarylamides as vanilloid-1 receptor modulators |
05/23/2012 | CN101061098B Novel pyridinone derivatives and their use as positive allosteric modulators of mglur2-receptors |
05/22/2012 | US8183378 Ligands, their preparation and uses thereof in asymmetric reactions |
05/17/2012 | US20120122924 Nampt inhibitors |
05/16/2012 | EP2044028B1 Cyanoisoquinoline compounds that stabilize hypoxia inducible factor (hif) |
05/16/2012 | CN102453001A Sulfomorpholine compounds, preparation method thereof and purpose thereof |
05/15/2012 | US8178678 Bis-quaternary ammonium salts and methods for modulating neuronal nicotinic acetylcholine receptors |
05/15/2012 | US8178557 Compounds and methods of use |
05/15/2012 | US8178550 Hydrochloride salts of 8-[{1-(3,5-Bis-(trifluoromethyl)phenyl)-ethoxy)-methyl]-8-phenyl-1,7-diaza-spiro[4.5]decan-2-one and preparation process therefor |
05/15/2012 | US8178545 Dual small molecule inhibitors of cancer and angiogenesis |
05/09/2012 | EP2450348A1 Novel diarylamine compound, and anti-aging agent, polymer composition, crosslinked rubber product and molded article thereof, and method for producing diarylamine compound |
05/09/2012 | CN102448941A Substituted isoquinoline derivative |
05/09/2012 | CN102442965A PAR-1 (protease-activated receptor-1) antagonists for treating thrombotic diseases, as well as preparation and application thereof |
05/09/2012 | CN101522633B 6-substituted isoquinoline derivatives as ROCK-I inhibitors |
05/08/2012 | US8173682 Substituted pyridones as inhibitors of poly(ADP-ribose) polymerase (PARP) |
05/08/2012 | US8173673 Biofilm-inhibiting effect and anti-infective activity of N,C-linked aryl isoquinolines and the use thereof |
05/08/2012 | US8173648 1,2,3,4-tetrahydroisoquinoline derivatives, preparation process therefor and pharmaceutical composition containing the same |
05/08/2012 | US8173639 Isoquinolinone derivatives as NK3 antagonists |
05/08/2012 | CA2507027C Isoquinoline compounds and medicinal use thereof |
05/03/2012 | US20120108629 New use of neferine |
05/03/2012 | US20120108603 Aminocarbonyl-derivatives as novel inhibitors of histone deacetylase |
05/02/2012 | EP1955697B1 2-aminobenzamide derivatives as vanilloid receptor 1 (vr1) inhibitors useful for the treatment of pain or bladder function disorder |
05/02/2012 | EP1724262B1 1-(2h)-isoquinolone derivative |
05/02/2012 | CN102438986A Isoquinolin-1 (2h) -one derivatives as parp-1 inhibitors |
04/26/2012 | US20120101125 Substituted isoquinoline derivatives, pharmaceutical compositions, and methods of use as beta-secretase inhibitors |
04/26/2012 | US20120101115 Compounds For Inducing Cellular Apoptosis |
04/26/2012 | US20120101097 Aryl sulfonamides |
04/25/2012 | EP2444395A1 Substituted isoquinoline derivative |
04/25/2012 | EP2101772B1 Intermediate duration neuromuscular blocking agents and antagonists thereof |
04/25/2012 | EP1745024B1 1-aryl-4-substituted isoquinolines |
04/25/2012 | CN102427853A Protease Inhibitors |