Patents
Patents for C07D 217 - Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems (11,865)
02/2012
02/02/2012US20120028956 Bicyclic mglur5 positive allosteric modulators and methods of making and using same
02/02/2012US20120028955 Bicyclic mglur5 positive allosteric modulators and methods of making and using same
02/02/2012CA2806821A1 Fused ring pyridine compound
02/01/2012EP2411361A1 1,1,1-trifluoro-2-hydroxypropyl compounds
02/01/2012CN101759637B N-芳基-3,4-二氢异喹啉盐及其作为制备杀螨和抗菌药物的应用 N- aryl-3,4-dihydro isoquinoline salts and their use as antimicrobial agents in the preparation and application of acaricidal
02/01/2012CN101668747B 四氢异喹啉-1-酮衍生物或其盐 Tetrahydro-isoquinoline-1-one derivative or a salt thereof
01/2012
01/31/2012US8106066 Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, pyrazolopyridines, isothiazolopyridines, and preparation and uses thereof
01/26/2012WO2012012543A1 Methods of use cyclic amide derivatives to treat sigma receptor-mediated disorders
01/26/2012WO2012012542A1 Methods of use of cyclic amide derivatives to treat schizophrenia
01/26/2012WO2012010843A1 Salt and solvates of a tetrahydroisoquinoline derivative
01/26/2012US20120022101 Salt and solvates of a tetrahydroisoquinoline derivative
01/26/2012US20120022080 Plasminogen Activator Inhibitor-1 Inhibitor
01/26/2012CA2803699A1 Salt and solvates of a tetrahydroisoquinoline derivative
01/25/2012EP2408744A1 Bicyclic compounds as inhibitors of diacylglycerol acyltransferase
01/25/2012CN102333759A Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders
01/25/2012CN102329266A Preparation method of dauriciline
01/24/2012US8101749 Process for the preparation of onium salts with a tetrafluoroborate anion having a reduced halide content
01/24/2012US8101640 Antibacterial agents
01/19/2012WO2012008984A1 (+)-morphinans as antagonists of toll-like receptor 9 and therapeutic uses thereof
01/19/2012US20120015993 Novel Pharmaceutical Forms, and Methods of Making and Using the Same
01/19/2012US20120015928 Amido Compounds And Their Use As Pharmaceuticals
01/19/2012CA2800971A1 Chemical compounds
01/19/2012CA2768199A1 (+)-morphinans as antagonists of toll-like receptor 9 and therapeutic uses thereof
01/18/2012EP2406257A1 A new method for the preparation of solifenacin and new intermediate thereof
01/18/2012EP1776119B1 Tetrahydro-naphthalene derivatives as glucocorticoid receptor modulators
01/18/2012CN102325754A Cyclic compound having hetero atom
01/18/2012CN102325750A Sulfonamides as trpm8 modulators
01/17/2012US8097758 Isoserine derivatives for use as coagulation factor IXa inhibitors
01/17/2012US8097636 Heterocyclic derivatives as modulators of ion channels
01/17/2012US8097627 Multiply-substituted tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents
01/17/2012CA2559611C Pyrrolidine compounds
01/12/2012WO2012006203A1 N-cyclyl-3 - (cyclylcarbonylaminomethyl) benzamide derivatives as rho kinase inhibitors
01/12/2012WO2012006202A1 Rho kinase inhibitors
01/12/2012WO2012004722A1 1-phenyl-substituted heterocyclyl derivatives and their use as prostaglandin d2 receptor modulators
01/12/2012CA2805452A1 1-phenyl-substituted heterocyclyl derivatives and their use as prostaglandin d2 receptor modulators
01/11/2012EP2150534B1 Isoquinolinone derivatives as nk3 antagonists
01/11/2012EP1994005B9 Tetrahydronaphthaline derivatives, methods for the production and use thereof as anti-inflammatory agents
01/11/2012EP1794128B1 Substituted 4-phenyltetrahydroisoquinolines, method for the production thereof, their use as a medicament, and a medicament containing them
01/11/2012EP1566380B1 Isoquinoline compounds and medicinal use thereof
01/11/2012CN101600698B Quinazolinone and isoquinolinone acetamide derivatives
01/11/2012CN101346353B Sulfonamide derivatives and use thereof for the modulation of metalloproteinases
01/10/2012US8093392 Caspase inhibitors and uses thereof
01/10/2012US8093266 Rho kinase inhibitors
01/10/2012US8093265 Bicycloheteroaryl compounds as P2X7 modulators and uses thereof
01/05/2012US20120003330 Benzoquinolone inhibitors of vmat2
01/04/2012EP2402322A1 1,2,3,4-tetrahydroisoquinoline derivative and its use as orexin receptor antagonist
01/04/2012EP1339663B1 Naphthalene derivatives
01/04/2012CN102307872A BCL-2-selective apoptosis-inducing agents for the treatment of cancer and immune diseases
01/04/2012CN102304110A Hydroxamates as therapeutic agents
01/03/2012US8088924 Pyridone derivatives having a binding activity to the cannabinoid type 2 receptor
01/03/2012US8088793 Certain chemical entities, compositions, and methods
12/2011
12/29/2011WO2011163610A2 Antimicrobial agents
12/29/2011WO2011162274A1 Isoquinoline derivative
12/29/2011US20110319622 Process of producing bleach boosters
12/29/2011US20110319390 6-Aminoisoquinoline Compounds
12/29/2011CA2803890A1 Antimicrobial agents
12/28/2011EP2398773A2 Novel polymorphs of saquinavir
12/28/2011EP1993560B1 Cannabinoid receptor antagonists/inverse agonists useful for treating obesity
12/28/2011CN101759636B 一种异喹啉的精提纯方法 Fine purification method isoquinoline
12/28/2011CN101550103B 1,2,3,4-四氢异喹啉衍生物及其合成方法和用途 1,2,3,4-tetrahydroisoquinoline derivatives and synthetic method and use
12/27/2011US8084615 Antibacterial agents
12/27/2011US8084464 Tetrahydroisoquinoline derivatives
12/22/2011US20110311482 Hepatitis C Virus Inhibitors
12/21/2011EP2397462A2 Compounds, compositions and methods of treatment for heart failure
12/21/2011EP1774968B1 Psycothropic agent and health food containing neferine
12/20/2011US8080562 Crystalline pharmaceutical and methods of preparation and use thereof
12/15/2011WO2011156626A1 Antimicrobial agents
12/15/2011WO2010095142A3 Novel polymorphs of saquinavir
12/15/2011US20110306624 Glucagon receptor antagonist compounds, compositions containing such compounds and methods of use
12/15/2011US20110306621 Acylguanidine derivatives
12/15/2011CA2810162A1 Antimicrobial agents
12/14/2011EP2394992A2 Substituted piperidine compounds and methods of their use
12/14/2011CN102276529A 一种猪毛菜碱的制备方法 Preparation of a salsoline
12/08/2011WO2011151423A1 Substituted isoquinolines and their use as tubulin polymerization inhibitors
12/08/2011CA2799653A1 Substituted isoquinolines and their use as tubulin polymerization inhibitors
12/07/2011EP2391623A1 Inhibitors of akt activity
12/07/2011CN1494425B 用作治疗剂的羧酰胺衍生物 As therapeutic agents carboxamide derivatives
12/07/2011CN102267944A 磷酸二甲啡烷中间体的制备方法 Preparation dimemorfan phosphate intermediates
12/07/2011CN102267924A 抗菌剂 Antibacterial agents
12/06/2011US8071762 Fused compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor
12/06/2011US8071650 Vanilloid receptor modulators; analgesic, antiinflammatory and antiulcer effects; such as 1-(1H-indol-5-ylmethyl)-3-phenethylthiourea
12/06/2011US8071618 Caspase inhibitors and uses thereof
12/06/2011US8071617 Modulators of cellular adhesion
12/06/2011US8071616 Pyridine, quinoline, and isoquinoline N-oxides as kinase inhibitors
12/06/2011US8071615 Carbonylamino-derivatives as novel inhibitors of histone deacetylase
12/06/2011CA2485430C Process for the preparation of a hydrate of an anthranilic acid derivative
12/06/2011CA2483662C Heterocyclic derivatives as opioid receptor modulators
11/2011
11/30/2011EP2389226A1 Bridged and fused heterocyclic antidiabetic compounds
11/30/2011CN102264704A 异喹啉衍生物 Isoquinoline derivatives
11/29/2011US8067600 Histone deacetylase inhibitors and methods of use thereof
11/29/2011US8067592 N-alkyny-2-(substituted aryloxy) alkylthioamine derivatives as fungicides
11/24/2011US20110288293 Isoquinoline derivative
11/24/2011US20110288120 Isoquinolinone derivatives as nk3 antagonists
11/24/2011US20110286922 Imaging and radiotherapy methods
11/24/2011US20110284832 Compound for organic optoelectronic device, organic light emitting diode including the same and display including the organic light emitting diode
11/23/2011EP2268617B1 Process for the resolution of isoquinoline derivatives
11/23/2011EP1951674B1 Sulfonamide derivatives and use thereof for the modulation of metalloproteinases
11/23/2011EP1671649B1 Dipeptidyl peptidase IV inhibitors for treating diabetic patients with sulfonylurea secondary failure
11/23/2011CN102256948A Isoquinolinone derivatives as nk3 antagonists
11/23/2011CN102256947A Substituted 4-(1,2,3,4-tetrahydroisochinolin-2-yl)-4-oxo-butyric acid amide as kcnq2/2 modulators
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