Patents
Sitemap › C07 - Organic chemistry › C07D - Heterocyclic compounds › C07D 217 - Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
Patents for C07D 217 - Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems (11,865)
01/2013
01/03/2013US20130004518 Cyclic amine bace-1 inhibitors having a benzamide substituent
01/03/2013CA2833824A1 Fluorinated arylalkylaminocarboxamide derivatives
01/02/2013CN102850271A Synthesis of 3-(1-aminoethyl)-2-cyclobutyl-2-hydro-isoquinolin-1-one compound
01/02/2013CN102358731B 2-substituted-6,7-dimethoxy tetralin isoquinoline derivative, preparation method thereof, medicinal composition and application thereof
01/02/2013CN101781247B New method for synthesizing substituted 3-quinoline carboxylic acid and analogue
01/01/2013US8343988 Inhibitors of histone deacetylase
12/2012
12/27/2012WO2012177782A1 Compounds and therapeutic uses thereof
12/27/2012WO2012175520A1 Hydroxy substituted isoquinolinone derivatives
12/27/2012WO2012175487A1 Cyclohexyl isoquinolinone compounds
12/27/2012WO2012174730A1 Preparative method and use of zyj-d08a and its epimers as histone deacetylase inhibitors
12/27/2012US20120330019 Hepatitis C Virus Inhibitors
12/26/2012CN102844305A Antibacterial isoquinolin-3-ylurea derivatives
12/25/2012US8338606 Crystalline forms of N-(tert-butoxycarbonyl)-3-methyl-L-valyl-(4R)-4-((7-chloro-4-methoxy-1-isoquinolinyl)oxy)-N-((1R,2S)-1-((cyclopropylsulfonyl)carbamoyl)-2-vinylcyclopropyl)-L-prolinamide
12/25/2012US8338449 Isoquinolinone potassium channel inhibitors
12/20/2012WO2012173983A1 Hepatitis c virus inhibitors
12/20/2012WO2012171506A1 Compounds, their pharmaceutical compositions and their uses as idh1 mutants inhibitors for treating cancers
12/20/2012US20120323003 Tetrahydroisoquinoline sulfonamide derivatives, the preparation thereof, and the use of the same in therapeutics
12/20/2012US20120322785 Substituted 6,6-fused nitrogenous heterocyclic compounds and uses thereof
12/20/2012CA2839616A1 Therapeutically active compositions and their methods of use
12/20/2012CA2839400A1 Hepatitis c virus inhibitors
12/19/2012EP2533782A1 PIPERAZINE DERIVATIVES FOR BLOCKING Cav2.2 CALCIUM CHANNELS
12/19/2012CN102827170A Active treatment compositions and use method thereof
12/19/2012CN101790514B 1-oxo-isoindoline-4-carboxamide and 1-oxo-1,2,3,4-tetrahydroisoquinoline-5-carboxamide derivatives, preparation and therapeutic use thereof
12/18/2012US8334316 Substituted organosulfur compounds and methods of using thereof
12/18/2012CA2719721C Tetrahydroisoquinoline derivative
12/18/2012CA2536576C Derivatives of hydroxamic acid as metalloproteinase inhibitors
12/13/2012US20120316337 Method for preparing chemical compounds of interest by nucleophilic aromatic substitution of aromatic carboxylic acid derivatives supporting at least one electro-attractive group
12/13/2012US20120316198 Hydrazone and diacyl hydrazine compounds and methods of use
12/12/2012EP2532643A1 IRE-1A Inhibitors
12/12/2012EP2531024A1 Derivatives of 4-(n-azacycloalkyl) aniilides as potassium channel modulators
12/12/2012CN102219737B Preparation process for key intermediate 1-(4-methoxyl)benzyl-1,2,3,4,5,6,7,8-octahydro isoquinoline (mixed isomer) of dextromethorphan hydrobromide serving as cough relieving medicine
12/11/2012CA2570942C Substituted tetrahydro-2h-isoquinolin-1-one derivatives, method for the production thereof, and use of the same as medicament
12/06/2012WO2012162814A1 Novel antibacterial combination therapy
12/06/2012CA2837759A1 Novel antibacterial combination therapy
12/05/2012EP2530075A2 Modulators of ATP-binding cassette transporters
12/05/2012CN102807526A Preparation method and application of histone deacetylase inhibitor ZYJ-D08a and epimer thereof
12/04/2012US8324384 Glucagon receptor antagonist compounds, compositions containing such compounds and methods of use
12/04/2012US8324203 Azadecalin glucocorticoid receptor modulators
11/2012
11/29/2012WO2012162513A2 Alcohol-, diol-, and carbohydrate-substituted indenoisoquinolines as topoisomerase i inhibitors
11/29/2012US20120299474 Light emitting tetraphenylene derivatives, its method for preparation and light emitting device using the same derivatives
11/28/2012EP2527328A1 Tetrahydroisoquinolines, pharmaceutical compositions containing them, and their use in therapy
11/28/2012EP2527315A1 Compounds, compositions and methods for the treatment of amyloid diseases and synucleinopathies such as Alzheimer's disease, type 2 diabetes and Parkinson's disease
11/28/2012EP2526948A1 RHO kinase inhibitors
11/28/2012EP2526947A1 Use of at least one isoquinoline compound of formula i, pharmaceutical composition for treating or preventing neurodegenerative diseases and method for treating or preventing neurodegenerative diseases
11/28/2012CN102803223A Cyclic compound having substituted phenyl group
11/28/2012CN101667626B Organic electroluminescent devices and metal complex compounds
11/28/2012CN101258130B Isoquinolines as igf-1r inhibitors
11/27/2012US8318941 Pyridone/hydroxypyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors
11/27/2012US8318768 Bronchodilating alpha, beta-unsaturated isoquinoline amides
11/27/2012CA2531766C Entry inhibitors of the hiv virus
11/27/2012CA2449830C New heterocyclic compounds, their preparation and their use as medicaments, in particular as anti-bacterial agents
11/22/2012WO2011109675A3 Process for the preparation of 2-(cyclohexylmethyl)-n-{2- [(2s)-1-methylpyrrolidin-2-yl]ethyl}-1, 2, 3, 4- tetrahydroisoquinoline-7-sulfonamide
11/22/2012US20120295856 Fredericamycin derivatives
11/21/2012CN102786482A Akt蛋白激酶抑制剂 Akt protein kinase inhibitor
11/20/2012US8314238 Process for the preparation of an enantiomeric trisubstituted 3,4-dihydro-isoquinoline derivative
11/20/2012US8314123 5, 6, or 7-substituted -3-(hetero) arylisoquinolinamine derivatives and therapeutic use thereof
11/20/2012US8314120 Small molecule potentiators of metabotropic glutamate receptors
11/14/2012CN1668721B Immunoadhesin comprising a glycoprotein VI domain
11/14/2012CN101611012B Cycloalkylamine substituted isoquinoline derivatives
11/13/2012US8309596 Kallikrein 7 modulators
11/13/2012US8309573 Salt of isoquinoline compound and crystal thereof
11/08/2012US20120283216 Fungicidal 2-(bicyclic aryloxy)carboxamides
11/07/2012EP2520561A1 IRE-1A Inhibitors
11/07/2012CN102770182A Substituted isoquinolinones and quinazolinones
11/07/2012CN101747262B Electron transporting-injection material and organic electroluminescent device using the same
11/07/2012CN101597259B Organic material and application thereof in organic electroluminescence device (OELD)
10/2012
10/31/2012EP2516009A1 Substituted isoquinolinones and quinazolinones
10/31/2012CN102757386A Peptide derivative and pharmaceutical composition and application thereof
10/31/2012CN102757370A Derivatives of p-aminobenzoic acid and applications thereof
10/31/2012CN101723896B Tyrosine derivative histone deacetylases inhibitor and application thereof
10/30/2012US8299253 Tris-quarternary ammonium salts and methods for modulating neuronal nicotinic acetylcholine receptors
10/30/2012US8299091 Aminoisoquinoline thrombin inhibitor with improved bioavailability
10/30/2012US8298512 Methods of determining β-III tubulin expression
10/30/2012CA2565293C Tetrahydroisoquinoline sulfonamide derivatives, the preparation thereof, and the use of the same in therapeutics
10/25/2012US20120270858 Isoquinoline, quinoline, and quinazoline derivatives as inhibitors of hedgehog signaling
10/24/2012EP2514743A1 Immunosuppressant Compounds and Compositions
10/24/2012CN102746225A Preparation method of 2-alkyl-3,4-disubstituted isoquinolyl-1(2H)-ketone derivative
10/24/2012CN102746224A Preparation method of 2-aryl-3,4-disubstituted isoquinolyl-1(2H)-ketone derivative
10/23/2012US8293912 Process for producing cisatracurium compounds and associated intermediates
10/23/2012US8293911 Derivatives of 4-(n-azacycloalkyl) anilides as potassium channel modulators
10/23/2012CA2566526C Naphthaline derivatives useful as histamine-3-receptor ligands
10/18/2012US20120263670 Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders
10/17/2012CN101747271B Method for preparing polysubstituted isoquinoline compounds
10/16/2012US8288537 Caspase inhibitors and uses thereof
10/16/2012CA2527396C Method for the treatment or prevention of lower urinary tract symptoms
10/16/2012CA2526884C P2x7 receptor antagonists and their use
10/11/2012US20120259094 Affinity ligands and methods for protein purification
10/11/2012US20120258929 Agent that modulates physiological condition of pests, involved in insect peptidyl-dipeptidase a activity
10/10/2012EP2507229A1 Sulfonamide derivatives as bcl-2-selective apoptosis-inducing agents for the treatment of cancer and immune diseases
10/10/2012CN102718708A Novel nitrogen-containing heteroaryl compounds and methods of use thereof
10/10/2012CN101450934B Sulfonyl-derivatives as novel inhibitors of histone deacetylase
10/10/2012CN101228132B Cyclohexylamin isoquinolone derivatives as rho-kinase inhibitors
10/04/2012WO2012131588A1 3-ureidoisoquinolin-8-yl derivatives
10/04/2012WO2012090179A3 Isoquinoline derivatives as cannabinoid receptor modulators
10/04/2012US20120252839 Gain-of-function bcl-2 inhibitors
10/04/2012US20120252790 Amino-Derivatives As Novel Inhibitors Of Histone Deacetylase
10/04/2012CA2828423A1 3-ureidoisoquinolin-8-yl derivatives
10/03/2012EP2504316A1 Heterocylic compounds as antagonists of the orexin receptors
10/03/2012CN101556990B Organic electroluminescent device using organic electroluminescent compounds
10/02/2012US8278442 Bicyclic aryl and heteroaryl compounds for the treatment of metabolic disorders
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