| Patents for C12P 35 - Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin (1,082) |
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| 08/16/1995 | EP0667396A1 Enzymatic acylation of 3-hydroxymethyl cephalosporins |
| 08/15/1995 | US5441874 Method for the acylation of the 7-amino group of the cephalosporanic ring |
| 08/04/1995 | CA2141008A1 Enzymatic acylation of 3-hydroxymethyl cephalosporins |
| 07/19/1995 | EP0663445A1 Process for producing 7beta-(4-carboxybutanamido)-cephalosporanic acid acylase ("GA) enzyme |
| 07/18/1995 | US5434259 Process for isolation of cefaclor after enzymatic acylation |
| 06/28/1995 | CN1104255A Method for preparation of 7-amino cephaloalkyl acid by one step and two enzyme method |
| 06/13/1995 | US5424203 Method for selectively deactivating catalase while retaining D-amino acid oxidase activity with a solution having a pH of about 11 to 12 |
| 06/13/1995 | US5424196 Enzymatic process for preparing 7-aminocephalosporanic acid and derivatives |
| 06/07/1995 | EP0465600B1 Enzymatic production of 7-amino cephalosporanic acid |
| 05/11/1995 | WO1995012680A1 A new cephalosporin c acylase |
| 05/11/1995 | CA2175338A1 A new cephalosporin c acylase |
| 04/26/1995 | EP0649899A1 Novel method for culturing filamentous fungi, carrier for immobilizing filamentous fungi and immobilized fungus composition for culturing |
| 04/04/1995 | US5403929 Treating zinc salt of cephalosporin c with metal halide, ion exchanging |
| 03/01/1995 | EP0640014A1 Separation method |
| 02/21/1995 | CA2006144C Microbial process for the production of immunosuppressive antibiotics |
| 02/15/1995 | EP0638649A2 New use of alcaligenes faecalis penicillin G acylase |
| 02/09/1995 | WO1995004149A1 Process for the efficient production of 7-adca via 3-(carboxyethylthio)propionyl-7-adca |
| 02/09/1995 | WO1995004148A1 Process for the efficient production of 7-adca via 2-(carboxyethylthio)acetyl-7-adca and 3-(carboxymethylthio)propionyl-7-adca |
| 02/09/1995 | CA2168431A1 Process for the efficient production of 7-adca via 2-(carboxyethylthio)acetyl-7-adca and 3(carboxymethylthio)propionyl-7-adca |
| 02/09/1995 | CA2168004A1 Process for the efficient production of 7-adca via 3-(carboxyethylthio)propionyl-7-adca |
| 02/02/1995 | WO1995003420A1 Process for the enzymatic preparation of a beta-lactam derivative |
| 10/12/1994 | EP0618979A1 AN IMPROVED METHOD FOR THE PREPARATION OF CERTAIN $g(b)-LACTAM ANTIBIOTICS |
| 10/11/1994 | US5354667 Process for the enzymatic preparation of 7-aminocephalosporanic acid |
| 09/28/1994 | CN1026015C Recombinant DNA expression vectors and DNA compounds that encode deacetoxycephalosporinc synthetase and deacetylcephalosporinc synthetase |
| 09/15/1994 | DE4407699A1 Verfahren zur Überführung von Cephalosporin C in Glutaryl-7-aminocephalosporansäure Process for the conversion of cephalosporin C to glutaryl-7-aminocephalosporanic |
| 08/18/1994 | WO1994018209A1 Improved process for isolation of cefaclor after enzymatic acylation |
| 08/18/1994 | CA2155530A1 Improved process for isolation of cefaclor after enzymatic acylation |
| 08/16/1994 | US5338676 Genetically engineered protein or enzyme |
| 08/16/1994 | US5338667 Microbiological process for the production of malonyl-7-amino-cephalosporanic acid derivatives using Sphingomonas sp. DSM 7007 |
| 08/09/1994 | US5336613 Cephalosporin C acylase |
| 07/26/1994 | US5332663 In the presence of microorganisms |
| 07/12/1994 | US5328839 Oxido reductase enzyme system obtained from P. chrysogenum |
| 06/15/1994 | EP0601996A1 Improved enzymatic oxidation of ceph C to glutaryl-7-amino-cephalosporanic acid |
| 06/14/1994 | US5320948 Cephalosporin C acylase |
| 06/07/1994 | US5318896 In situ expression of expandase gene; ring expansion of adipoyl-6-amino penicillanic acid; cleavage of adipoyl side chain |
| 05/25/1994 | CN1087118A A transformant capable of producing d-amino acid oxidase |
| 05/17/1994 | US5312750 Genetic engineering for glucose detection |
| 05/10/1994 | US5310659 GL-7ACA acylase |
| 04/13/1994 | CN1085252A A new cephalosporin C acylase |
| 03/22/1994 | US5296358 Process for the enzymatic preparation of cephalosporanic derivatives using a D-amino acid oxidase from Rhodotorula glutinis NCIMB 40412 |
| 02/23/1994 | EP0583817A2 A transformant capable of producing D-amino acid oxidase |
| 02/23/1994 | CN1082610A A method for the acylation of the 7-amino group of the cephalosporanic ring |
| 02/22/1994 | CA1327170C Recombinant dna expression vectors and dna compounds that encode deacetoxycephalosporin c synthetase and deacetylcephalosporin c synthetase |
| 02/16/1994 | CN1081929A Separation method |
| 02/09/1994 | EP0582102A2 A method for the acylation of the 7-amino group of the cephalosporanic ring |
| 02/08/1994 | US5284754 Process for the continuous conversion of cephalosporin derivatives into glutaryl-7-aminocephalosporanic acid derivatives |
| 02/08/1994 | CA2103696A1 A method for the acylation of the 7-amino group of the cephalosporanic ring |
| 01/25/1994 | US5281525 Cephalosporin acetylhydrolase gene from Bacillus subtilis |
| 01/19/1994 | EP0578761A1 Enzymatic process for the production of cefonicid |
| 12/15/1993 | EP0573849A2 7-amino-3-methoxymethyl-3-cephem-4-carboxy acid ester-hydrolase, method of its production and its utilization |
| 12/07/1993 | US5268271 Method for the synthesis of semi-synthetic antibiotics in thermodynamically controlled water-cosolvent organic miscible apolar systems by using penicillin G acylase |
| 12/07/1993 | CA2097770A1 7-amino-3-methoxymethyl-3-cephem-4-carboxylic ester hydrolase, process for its preparation, and its use |
| 11/25/1993 | WO1993023164A1 Separation method |
| 11/18/1993 | EP0569462A1 Process for separation of two solid components |
| 11/03/1993 | EP0568004A2 Microbiological process for the preparation of malonyl-7-aminocephalosporanic acid derivatives |
| 11/03/1993 | CN1077989A Microbiological process for preparation of malonyl-7-aminocephalosporansaur-derivative |
| 10/30/1993 | CA2095166A1 Microbiological process for the production of malonyl-7-aminocephalosporanic acid derivatives |
| 10/27/1993 | EP0567323A2 Improved process for preparing cephalosporins |
| 10/27/1993 | EP0566897A2 The complete gene (cefG) encoding the acetyl-CoA: deacetylcephalosporin C acetyltransferase of Cephalosporium acremonium, its isolation and use |
| 10/27/1993 | CN1077749A Improved process for preparing cephalosporins |
| 10/25/1993 | CA2094686A1 Process for preparing cephalosporins |
| 10/08/1993 | CA2093498A1 Complete gene (cefg) encoding the acetyl-coa: deacetylcephalosporin c acetyltransferase of cephalosporium acremonium, its isolation and use |
| 09/01/1993 | EP0558241A2 A new cephalosporin C acylase |
| 08/28/1993 | CA2090571A1 Cephalosporin c acylase |
| 08/18/1993 | CN1075336A Novel bioprocess for preparing 7-ADCA |
| 07/21/1993 | EP0551750A2 Recombinant DNA compounds and expression vectors encoding para-nitrobenzyl esterase activity from bacillus |
| 07/21/1993 | CN1074484A Novel bioprocesses for preparing 7-ACA and 7-ADAC |
| 07/20/1993 | US5229274 Gene encoding one step cephalosporin C amidase and expression thereof in recombinant bacillus |
| 06/30/1993 | EP0549264A1 Purified para-nitrobenzyl esterase from bacillus |
| 06/24/1993 | WO1993012250A1 AN IMPROVED METHOD FOR THE PREPARATION OF CERTAIN β-LACTAM ANTIBIOTICS |
| 06/21/1993 | CA2085803A1 Purified para-nitrobenzyl esterase from bacillus |
| 06/20/1993 | CA2085806A1 Recombinant dna compounds and expression vectors encoding para-nitrobenzyl esterase activity from bacillus |
| 05/12/1993 | CN1071953A Process for fermentative production of cephalosporin c using acremonium chrysogenum |
| 05/05/1993 | EP0540210A1 Novel bioprocesses for preparing 7-aca and 7-adac |
| 05/04/1993 | CA1317246C Process for the enzymatic hydrolysis of -aminoadipinyl-monoamino compounds |
| 04/29/1993 | WO1993008287A1 Novel bioprocesses for preparing 7-aca and 7-adac |
| 04/21/1993 | EP0537255A1 PROCESS FOR PREPARATION OF $g(b)-LACTAMS |
| 04/07/1993 | EP0311640B1 Higher alkyl pyrrolidone extractants for water soluble phenolic or carboxylic antibiotics |
| 03/18/1993 | WO1993005158A1 Novel bioprocess for preparing 7-adca |
| 03/17/1993 | EP0532341A1 Novel bioprocess for preparing 7-ADCA |
| 03/09/1993 | US5192678 Hydrolysis, antibiotics |
| 03/04/1993 | WO1993004188A1 Method for the fermentative production of cephalosporin c using acremonium chrysogenum |
| 03/04/1993 | CA2116019A1 Process for the fermentative production of cephalosporin c using acremonium chrysogenum |
| 02/03/1993 | EP0525861A1 Process for the enzymatic preparation of 7-amino-cephalosporanic acids |
| 01/25/1993 | CA2074032A1 Process for the enzymatic preparation of 7-amino-cephalosporanic acids |
| 12/09/1992 | EP0517200A2 Process for the enzymatic production of cephalosporane derivatives |
| 12/04/1992 | CA2070083A1 Process for the enzymatic preparation of cephalosporanic derivatives |
| 11/10/1992 | US5162228 Gylceraldehyde-3-phosphate dehydrogenase gene and promoter |
| 10/20/1992 | US5156960 Microbial process for the production of immunosuppressive antibiotics |
| 10/15/1992 | WO1992017600A1 Enzymatic process for the production of cefonicid |
| 10/15/1992 | WO1992017496A1 Isolation and sequence of the acetyl coa:deacetylcephalosporin acetyltransferase gene |
| 10/15/1992 | CA2107661A1 Enzymatic process for the production of cefonicid |
| 08/05/1992 | EP0496993A1 Enzymatic process for preparing 7-aminocephalosporanic acid and derivatives |
| 07/26/1992 | WO1992012782A1 Process for separation of two solid components |
| 07/26/1992 | CA2101256A1 Process for separation of two solid components |
| 07/01/1992 | EP0492495A2 Immobilized D-amino acid oxidase and its use for the production of drugs |
| 06/25/1992 | CA2058194A1 Immobilized d-amino acid oxidase and its use for the preparation of medicaments |
| 05/19/1992 | CA1301098C Purified enzyme and process therefor |
| 04/29/1992 | EP0482844A2 GL-7ACA acylase |
| 04/14/1992 | US5104800 A bacillus megaterium culture product; cleavage of the aminoadipoyl side chain |