| Patents for C12P 35 - Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin (1,082) |
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| 05/20/1998 | EP0843013A2 Novel bioprocess for preparing 7-ADCA |
| 05/19/1998 | US5753458 Acylation method for penicillins and cephalosporins |
| 05/14/1998 | WO1998020120A1 Mutant penicillin g acylases |
| 05/13/1998 | EP0841338A1 Process for purifying 7-substituted-amino-desacetoxy-cephalosporines through the use of filtration membranes |
| 04/23/1998 | WO1998016648A2 Isopenicillin n synthetase and deacetoxycephalosporin c synthetase enzymes and methods |
| 04/22/1998 | CN1179795A Process for preparation of 'beta'-lactam antibiotic |
| 04/22/1998 | CN1179779A Process for recovery of cephalexin |
| 04/21/1998 | US5741657 Measuring gene expression |
| 04/08/1998 | CN1178220A Process for producing cefazolin |
| 04/01/1998 | EP0832892A1 Process for purifying cephalexin |
| 03/24/1998 | US5731165 Process for the production of 7-ADCA via expandase activity on penicillin G |
| 03/18/1998 | EP0828850A1 Process for the production of 7-adca via expandase activity on penicillin g |
| 03/10/1998 | US5726032 Process for the efficient production of 7-ADCA via 2-(carboxyethylthio)acetyl-7-ADCA and 3-(carboxymethylthio)propionyl-7-ADCA |
| 02/19/1998 | WO1998002567A3 PROCESS FOR THE PREPARATION OF CEPHALOSPORINS USING $i(ACREMONIUM CHRYSOGENUM) |
| 02/19/1998 | WO1998002551A3 Process for the production of adipoyl cephalosporins |
| 02/11/1998 | EP0822981A1 Enzymatic production of halogenated cephalosporin |
| 02/05/1998 | WO1998004732A1 SYNTHESIS OF β-LACTAM ANTIBACTERIALS USING SOLUBLE SIDE CHAIN ESTERS AND ENZYME ACYLASE |
| 02/05/1998 | CA2253521A1 Synthesis of .beta.-lactam antibacterials using soluble side chain esters and enzyme acylase |
| 02/03/1998 | US5714363 Polypeptide synthetase having the catalytic hydrolysis activity, changing 3-exomethylenecephalosporin c to deacetylcephalosporin c |
| 01/22/1998 | WO1998002567A2 PROCESS FOR THE PREPARATION OF CEPHALOSPORINS USING $i(ACREMONIUM CHRYSOGENUM) |
| 01/22/1998 | WO1998002551A2 Process for the production of adipoyl cephalosporins |
| 01/14/1998 | EP0817785A2 Substrates for beta-lactamase and uses thereof |
| 01/07/1998 | EP0815256A1 Process for the preparation of a beta-lactam antibiotic |
| 12/09/1997 | US5695951 Chlorination of cephalexin with chloroperoxidase from Rathayibacter biopuresis |
| 11/26/1997 | EP0712443B1 Process for the enzymatic preparation of a beta-lactam derivative and separation of d-phenylglycine amide |
| 10/30/1997 | WO1997040171A1 Process for producing the enzyme d-aminoacido oxydase of rhodotorula gracilis in host cells |
| 10/22/1997 | EP0801686A1 Process for preparing cyclosporin a |
| 10/15/1997 | CN1162337A Process of producing beta-lactam antibiotics applying microorganisms with increased ligase activity |
| 10/14/1997 | US5677141 Process for producing 7-aminocephem compound or salts thereof |
| 09/25/1997 | WO1997034902A1 Process for purifying 7-substituted-amino-desacetoxy-cephalosporines through the use of filtration membranes |
| 09/03/1997 | CN1158638A Mutated penicilling acylase Genes |
| 08/05/1997 | US5654425 Having an easily hydrolyzible phenylacetyl- or phenoxyacetyl-blocking group on the amino group of an 7-(2-aminothiazol-4-yl)acetylcephalosporin; chemical intermediates |
| 07/30/1997 | EP0786006A2 Cephalosporin c amidohydrolase, production and use |
| 07/29/1997 | US5652132 Oxido reductase enzyme system obtainable from P. chrysogenum, the set of genes encoding the same and the use of oxido reductase enzyme systems or genes encoding the same for increasing antibiotic production |
| 07/17/1997 | WO1997020053A3 Improved process for the production of semi-synthetic cephalosporins via expandase activity on penicillin g |
| 07/16/1997 | EP0783582A1 PROCESS OF PRODUCING $g(b)-LACTAM ANTIBIOTICS APPLYING MICROORGANISMS WITH INCREASED LIGASE ACTIVITY |
| 06/26/1997 | WO1997022610A1 Process for the preparation of an antibiotic |
| 06/25/1997 | CN1152945A Process for preparation of beta-lactams at constantly high concentration of reactants |
| 06/05/1997 | WO1997020053A2 Improved process for the production of semi-synthetic cephalosporins via expandase activity on penicillin g |
| 05/28/1997 | EP0775210A1 Mutated penicillin g acylase genes |
| 05/28/1997 | CN1150823A A new cephalosporin C acylase |
| 05/13/1997 | US5629171 Recombinant bioprocess for the preparation of 7-amino cephalosporanic acid (7-ACA) |
| 05/07/1997 | EP0771357A1 PROCESS FOR PREPARATION OF $g(b)-LACTAMS AT CONSTANTLY HIGH CONCENTRATION OF REACTANTS |
| 04/08/1997 | US5618687 Production of 7-amino cephalosporanic acid with D-amino oxidase and deacylase |
| 03/19/1997 | EP0763129A1 Dna encoding cephamycin biosynthesis late enzymes |
| 03/18/1997 | US5612210 Culture of escherichia to produce enzyme |
| 03/05/1997 | CN1144274A Improved enzymatic process for producing penicillins and cephalosporins |
| 02/11/1997 | US5602016 D-amino acid oxidase from F. solani and DNA therefor |
| 02/04/1997 | US5599702 D-amino acid oxidase from Trigonopsis variabilis immobilized on porous copolymer beads |
| 01/28/1997 | US5597704 Bioconversion of cephalosporin C to glutaryl-7-aminocephalosporanic acid |
| 01/09/1997 | WO1996030540A3 Substrates for beta-lactamase and uses thereof |
| 12/31/1996 | US5589354 Halogenation of cephalexin with haloperoxidase from Rathayibacter biopuresis |
| 12/11/1996 | CN1137568A Process for enzymatic synthesis of beta-lactam antibiotics in presence of enzyme inhibitor |
| 12/05/1996 | WO1996038580A1 Process for the production of 7-adca via expandase activity on penicillin g |
| 12/05/1996 | WO1996016174A3 Cephalosporin c amidohydrolase, production and use |
| 12/05/1996 | CA2223105A1 Process for the production of 7-adca via expandase activity on penicillin g |
| 10/03/1996 | WO1996030540A2 Substrates for beta-lactamase and uses thereof |
| 10/02/1996 | EP0734452A1 Improved acylation method for penicillins and cephalosporins |
| 09/24/1996 | US5559006 Method for selectively deactivating catalase while retaining damino acid oxidase activity |
| 09/24/1996 | US5559005 Bioprocess for preparing 7-ACA and 7-ADAC |
| 09/11/1996 | CN1130506A Pharmaceutical formulations of cefaclor |
| 09/04/1996 | EP0730036A1 Process for the enzymatic synthesis of beta-lactam antibiotics in the presence of an enzyme inhibitor |
| 09/04/1996 | EP0730035A1 Improved enzymatic process for producing penicillins and cephalosporins |
| 08/29/1996 | CA2167118A1 Enzymatic process for producing penicillins and cephalosporins |
| 08/21/1996 | EP0726958A1 A new cephalosporin c acylase |
| 08/08/1996 | WO1996023897A1 PROCESS FOR THE PREPARATION OF A β-LACTAM ANTIBIOTIC |
| 08/08/1996 | WO1996023797A1 PROCESS FOR THE RECOVERY OF A β-LACTAM ANTIBIOTIC |
| 08/08/1996 | WO1996023796A1 Process for the recovery of cephalexin |
| 08/07/1996 | CN1128545A Process for the efficient production of 7-ADCA VIA 3-(carboxyethylthio)propionyl-7-ADCA |
| 07/31/1996 | CN1128045A Process for the efficient production of 7-ADCA via 2-(carboxyethylthio)acetyl-7-ADCA and 3-(carboxymethylthio)propionyl-7-ADCA |
| 07/24/1996 | CN1127531A Process for the enzymatic preparation of a beta-lactam derivative |
| 06/27/1996 | WO1996019569A1 Enzymatic production of halogenated cephalosporin |
| 06/19/1996 | EP0716852A1 Pharmaceutical formulations of cefaclor |
| 06/19/1996 | EP0716698A1 Process for the efficient production of 7-ADCA via 2-(carboxyethylthio)acetyl-7-ADCA and 3-(carboxymethylthio)propionyl-7-ADCA |
| 06/18/1996 | US5527697 An esterase prepared by cultivation of microorganism of streptomyces, amycolatopsis or nocardia |
| 06/14/1996 | CA2158511A1 Pharmaceutical formulations of cefaclor |
| 06/11/1996 | US5525483 By enzymatic reaction with parent amino beta-lactam |
| 05/30/1996 | WO1996016174A2 Cephalosporin c amidohydrolase, production and use |
| 05/22/1996 | EP0712443A1 Process for the enzymatic preparation of a beta-lactam derivative and separation of d-phenylglycine amide |
| 05/15/1996 | EP0711348A1 Process for the efficient production of 7-adca via 3-(carboxyethylthio)propionyl-7-adca |
| 04/30/1996 | US5512454 Enzymatic acylation of 3-hydroxymethyl cephalosporins |
| 04/25/1996 | WO1996012031A1 Process for preparing cyclosporin a |
| 04/10/1996 | EP0682669A4 Improved process for isolation of cefaclor after enzymatic acylation. |
| 04/04/1996 | WO1996010085A1 PROCESS OF PRODUCING β-LACTAM ANTIBIOTICS APPLYING MICROORGANISMS WITH INCREASED LIGASE ACTIVITY |
| 04/04/1996 | CA2201485A1 Process of producing .beta.-lactam antibiotics applying microorganisms with increased ligase activity |
| 03/27/1996 | CN1119439A Improved process for isolation of cefaclor after enzymatic acylation |
| 02/22/1996 | WO1996005318A1 Mutated penicillin g acylase genes |
| 02/01/1996 | WO1996002663A1 PROCESS FOR PREPARATION OF β-LACTAMS AT CONSTANTLY HIGH CONCENTRATION OF REACTANTS |
| 12/21/1995 | WO1995034675A1 Improved acylation method for penicillins and cephalosporins |
| 12/12/1995 | US5474912 Method for increasing production of microbial metabolites by genetic engineering |
| 12/06/1995 | CN1112927A Enzymatic acylation of 3-hydroxymethyl cephalosporins |
| 12/05/1995 | US5472853 Enzymatic process for cephalosporins |
| 11/28/1995 | US5470717 Method for the preparation of certain β-lactam antibiotics |
| 11/22/1995 | EP0682669A1 Improved process for isolation of cefaclor after enzymatic acylation |
| 11/21/1995 | US5468632 Recombinant DNA compounds and expression vectors encoding para-nitrobenzyl esterase activity from bacillus |
| 11/14/1995 | US5466598 Deacetylcephalosporin C acetyltransferase from Acremonium chrysogenum |
| 11/08/1995 | EP0599891B1 Method for the fermentative production of cephalosporin c using acremonium chrysogenum |
| 11/02/1995 | WO1995029253A1 Dna encoding cephamycin biosynthesis late enzymes |
| 11/02/1995 | CA2188257A1 Dna encoding cephamycin biosynthesis late enzymes |
| 09/26/1995 | US5453374 Trigonopsis transformant producing D-amino acid oxidase |