| Patents for C12P 35 - Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin (1,082) |
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| 02/15/2006 | EP0537255B1 Process for preparation of beta-lactams |
| 02/08/2006 | CN1732256A Process for protection of insoluble enzymatic biocatalysts, biocatalyst obtained thereof and bioreactor with the immobilized biocatalyst |
| 02/07/2006 | US6995003 Altering the consensus C-terminal targeting sequence of desacetoxycephalosporin C synthetase, a modified enzymes expressed from recombinant DNA in host cell Penicillium chrysogenum; improve cephalosporins production |
| 12/14/2005 | CN1706963A Process for the fermentative production of deacylated cephalosporins |
| 11/30/2005 | CN1703514A Fermentation of pentose sugars |
| 11/23/2005 | EP1322751B1 Glutaryl cephalosporin amidase from pseudomonas diminuta bs-203 |
| 11/15/2005 | US6964865 Host cells comprising Streptomyces clavuligerus chromosomal DNA fragments encoding enzymes for β-lactam antibiotic biosynthesis |
| 10/19/2005 | CN1685059A Method for producing cephalexin |
| 10/12/2005 | CN1681841A Process for production of cephalosporin C |
| 10/12/2005 | CN1680583A Use of recommbined D-amino acid oxidase |
| 09/28/2005 | EP0786006B1 Cephalosporin c amidohydrolase, production and use |
| 09/27/2005 | US6949356 Methods for improving secondary metabolite production in fungi |
| 09/21/2005 | EP1576102A2 Amidases, nucleic acids encoding them and methods for making and using them |
| 09/14/2005 | CN1667116A Microorganism strain and method for converting cephalosporin C into deacetylate cephalosporin C by using same |
| 09/13/2005 | US6942990 Glutaryl cephalosporin amidase from Pseudomonas diminuta BS-203 |
| 09/08/2005 | US20050196828 Bioreactor with expandable surface area for culturing cells |
| 08/18/2005 | WO2005075652A1 Process for producing modified ϝ-glutamyltranspeptidase (modified ggt) having enhanced glutaryl-7-aminosephalosporanic acid (gl-7-aca) acylase activity |
| 08/03/2005 | CN1213144C Recombination nucleic acid molecule and application thereof |
| 07/27/2005 | EP1556500A1 Simple enzymatic process for preparing cefazolin |
| 07/21/2005 | US20050158818 Recombinant hydrolase for use in the preparation of 7-amino-cephalosporanic acid; bioreactors |
| 07/20/2005 | CN1641019A Cephalosporin C acylases |
| 07/13/2005 | EP1553175A1 Cephalosporin C acylase mutants |
| 06/22/2005 | EP1543027A1 Process for production of cephalosporin c |
| 06/16/2005 | WO2005054452A2 Glutaryl amidases and their uses |
| 06/15/2005 | EP1539923A2 Bioreactor with expandable surface area for culturing cells |
| 06/14/2005 | US6905854 Mutated penicillin expandase and process for preparing 7-ADCA using the same |
| 06/09/2005 | WO2004062558A3 Process for enzymatic synthesis of βετα-lactam antibiotics |
| 06/08/2005 | EP1538205A1 Glutaryl amidases and their uses |
| 05/26/2005 | WO2005003367A3 Process for the preparation of cephradine |
| 04/21/2005 | US20050084925 Method for producing cephalexin |
| 03/10/2005 | US20050054031 Method for producing novel beta-lactam antibiotic from protoplast fusion strain |
| 03/03/2005 | WO2005019468A1 Modified dacs/daoc enzymes |
| 03/02/2005 | EP0783582B1 PROCESS OF PRODUCING $g(b)-LACTAM ANTIBIOTICS APPLYING MICROORGANISMS WITH INCREASED LIGASE ACTIVITY |
| 02/17/2005 | WO2005014821A1 Cephalosporin c acylase mutant and method for preparing 7-aca using same |
| 02/17/2005 | WO2004020572A3 Bioreactor with expandable surface area for culturing cells |
| 02/10/2005 | US20050032151 Using radio frequency identification to improve database storage and information retrieval/sharing; libraries and information management |
| 01/13/2005 | WO2005003367A2 Process for the preparation of cephradine |
| 12/29/2004 | WO2004113508A1 Production of cephalosporin intermediates in penicillium chrysogenum |
| 12/29/2004 | CN1557962A Production method of 7-amino cephalosporanic acid |
| 12/23/2004 | WO2004111241A1 Penicillin acylase |
| 12/23/2004 | US20040259191 having higher activity on penicillin G; use to produce phenylacetyl-7-aminodeacetoxycephalosporanic acid (7-ADCA) |
| 11/18/2004 | WO2004020650A3 An enzymatic process for preparing beta-lactams |
| 11/10/2004 | CN1544620A Method for producing 7-amino cephalosporanic acid and its specific recombinase |
| 11/09/2004 | US6815189 For the synthesis of deacetylated derivatives; gene expression inhibition |
| 11/03/2004 | CN1174096C Spherical particles containing microorganism cells having enzyme activity, preparation method and use thereof |
| 10/20/2004 | EP1468093A1 Fermentation of pentose sugars |
| 10/13/2004 | EP1466006A1 Method for producing cephalexin |
| 10/12/2004 | US6803460 Acidification; carbonation |
| 09/29/2004 | EP0912754B1 Process for the fermentative production of deacylated cephalosporins |
| 09/22/2004 | EP0716698B1 Process for the efficient production of 7-ADCA via 2-(carboxyethylthio)acetyl-7-ADCA and 3-(carboxymethylthio)propionyl-7-ADCA |
| 09/22/2004 | CN1531598A Enzymatic process for preparing cephalosporanic acid derivatives |
| 09/22/2004 | CN1531539A Enzymatic process for preparing cephalosporanic acid derivatives using 2-ketoacid derivatives |
| 09/16/2004 | US20040181056 using an enzyme system that comprises co-immobilised D-Amino acid oxidase and catalase; chemical intermediates for Cephalosporin C and derivatives |
| 09/09/2004 | US20040175783 Generating 3-cephalosporin C derivatives which are used in the preparation of beta -lactam antibiotics using immobilized biocatalyst; solid phase synthesis |
| 09/08/2004 | CN1165626C Process for preparation of beta-lactam antibiotic |
| 08/19/2004 | WO2004069848A2 Amidases, nucleic acids encoding them and methods for making and using them |
| 08/04/2004 | CN1517442A Method for purifying cephalosporin C broth using adsorbent |
| 07/29/2004 | WO2004062558A2 Process for enzymatic synthesis of βετα-lactam antibiotics |
| 07/28/2004 | CN1515679A Enzyme no-containing esterase |
| 07/28/2004 | CN1159444C Mutated penicilling acylase genes |
| 07/22/2004 | WO2003076640A8 A process for the preparation of cephalosporan acid derivatives from cephalosporin c |
| 07/14/2004 | CN1511956A Crystallizing method for 7-amino cephalo phytanic acid |
| 06/30/2004 | CN1155712C Process for preparing enzyme encoded by cephalosporin acetylthydrolase gene |
| 06/24/2004 | US20040121425 having higher activity on penicillin G; phenylacetyl-7-aminodeacetoxycephalosporanic acid (7-ADCA); genetic engineering |
| 06/23/2004 | EP1009849B1 Improvements in or relating to the preparation of lactam compounds |
| 06/17/2004 | WO2004050893A1 Method for producing cephalexin |
| 06/17/2004 | DE10256656A1 Verfahren zur Herstellung von Cephalexin A process for the production of Cephalexin |
| 05/26/2004 | CN1151261C Double gene coexpression plasmid, construction method and application thereof |
| 05/19/2004 | DE10251747A1 Gentechnisch veränderte Penicillinamidase und Verfahren zu ihrer Herstellung Genetically modified penicillin and process for their preparation |
| 05/13/2004 | WO2004039997A1 Simple enzymatic process for preparing cefazolin |
| 05/12/2004 | EP1418230A2 Genetically modified penicillin amidase and methods of producing it |
| 05/12/2004 | CN1495259A Production of valuable compound by using chemically defined culture medium and adopting industrial scal fermentation process |
| 05/06/2004 | WO2004020652A3 An enzymatic process for preparing beta-lactams |
| 05/06/2004 | US20040087000 Isopenicillin N synthetase and deacetoxycephalosporin C synthetase enzymes and method |
| 05/06/2004 | EP1416054A1 Simple enzymatic process for preparing cefazolin |
| 05/04/2004 | US6730497 Enzymatically converting a 3-thiolated cephalosporin c into a 3-thiolated-alpha-ketoadipyl-7-aminocephalosporanic acid derivative of use in the preparation of cephalosporin c antibiotics and derivatives thereof |
| 04/22/2004 | US20040077039 By fungi through genetic manipulation of such fungi |
| 04/22/2004 | US20040077035 Mutated penicillin expandase and process for preparing 7-ADCA using the same |
| 04/22/2004 | US20040077034 Mutated penicillin expandase and process for preparing 7-ADCA using the same |
| 04/21/2004 | EP1409530A2 Modulation of secondary metabolite production by zinc binuclear cluster proteins |
| 04/14/2004 | CN1145703C Process for fermentative production of deacylated cephaloporins |
| 04/08/2004 | US20040067549 A process for the preparation of 3-thiolated derivatives of 3-acetoxy-methyl-7-amino-ceph-3-em-carboxylic acid; antibiotics |
| 04/07/2004 | EP1405922A2 Substrates for beta-lactamase and uses thereof |
| 04/01/2004 | WO2004026902A1 Process for production of cephalosporin c |
| 03/23/2004 | US6709859 Chromosomal DNA Fragments Encoding Enzymes for Encoding B-Lactam Biosynthesis Enzymes, and Vector and Transformants for Their Expression |
| 03/18/2004 | US20040053912 An enzymatic deacylation of a beta -lactam compound ( containing a beta-lactam nucleus with a side chain coupled to it via an amide bond) in presence of organic solvent, and leads to a beta-lactam nucleus and a carboxylic acid |
| 03/11/2004 | WO2004020652A2 An enzymatic process for preparing beta-lactams |
| 03/11/2004 | WO2004020651A1 An enzymatic process for preparing beta-lactams |
| 03/11/2004 | WO2004020650A2 An enzymatic process for preparing beta-lactams |
| 03/11/2004 | WO2004020649A1 AN ENZYMATIC PROCESS FOR PREPARING β-LACTAMS |
| 03/11/2004 | WO2004020572A2 Bioreactor with expandable surface area for culturing cells |
| 03/11/2004 | CA2496950A1 Bioreactor with expandable surface area for culturing cells |
| 03/03/2004 | EP1394262A1 An enzymatic process for preparing beta-lactams |
| 03/02/2004 | US6699699 Having a better substrate specificity to penicillin g, wherein the mutated penicillin expandase comprises an amino acid substitution at one or more residual positions corresponding to those of a wild-type |
| 02/26/2004 | WO2002024865A3 Modulation of secondary metabolite production by zinc binuclear cluster proteins |
| 02/18/2004 | CN1138781C Process for recovery cephalosporin from fermentative liquid |
| 02/05/2004 | US20040023257 Comprises nucleotide sequences coding proteolytic enzymes for increasing flavor in food, promoting microbiocidal activity, modifying and deprotecting chemical intermediates, synthesis and hydrolysis of cephalosporins |
| 02/04/2004 | CN1137271C Improved process for fermentative production of cephalosporin |
| 02/04/2004 | CN1136852C Pharmaceutical formulations of cefaclor |
| 01/21/2004 | EP1381690A2 Enzymatic process for preparing cephalosporin derivatives |