Patents for C12P 35 - Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin (1,082)
03/1992
03/18/1992EP0475652A2 Cephalosporin C acylase
03/11/1992EP0474211A2 Process for the continuous transformation of cephalosporin derivatives in glutaryl-7-amino-cephalosporin derivatives
03/10/1992CA1297056C Cephem compounds and their production
03/06/1992CA2050615A1 Process for the continuous conversion of cephalosporin derivatives into glutaryl-7-aminocephalosporanic acid derivatives
03/04/1992EP0473008A2 Improved process for preparing penicillins and cephalosporins
02/1992
02/05/1992EP0469919A2 A process for the enzymatic preparation of 7-aminocephalosporanic acid
01/1992
01/23/1992WO1992001061A1 PROCESS FOR PREPARATION OF β-LACTAMS
01/22/1992CN1058045A Cephalosporin acetylhydrolase gene and protein encoded by said gene
01/21/1992US5082772 Process for preparing deacetylcephalosporin c
01/07/1992US5079146 Penicillinacylase is used to remove ester protecting group
12/1991
12/27/1991EP0462674A1 An oxido reductase enzyme system obtainable from P. chrysogenum, the set of genes encoding the same and the use of oxido reductase enzyme systems or genes encoding the same for increasing antibiotic production
12/26/1991WO1991019788A1 An oxido reductase enzyme system obtainable from p. chrysogenum, the set of genes encoding the same and the use of oxido reductase enzyme systems or genes encoding the same for increasing antibiotic production
12/04/1991EP0458932A1 Method for the synthesis of semi-synthetic antibiotics in thermodynamically controlled water-cosolvent organic miscible apolar systems by using penicillin g acylase
10/1991
10/30/1991EP0454478A1 Cephalosporin acetylhydrolase gene and protein encoded by said gene
10/30/1991CN1014528B Process for producing compounds of the kind of cephalosporin
10/09/1991EP0450758A1 An acetyltransferase gene-containing DNA
09/1991
09/25/1991EP0448180A2 A method of modulating the production of secondary metabolites
09/11/1991EP0445868A1 A method for influencing beta-lactam antibiotic production and for isolation of large quantities of ACV synthetase
09/04/1991EP0444758A1 Method for modification of ACV synthetase and use of the modified enzyme for production of beta-lactam antibiotics
07/1991
07/17/1991EP0211033B1 A d-amino acid oxidase and method for isolation thereof
07/10/1991EP0436355A2 Process for producing 7-aminocephem compound or salts thereof
06/1991
06/27/1991WO1991009136A1 Method for the synthesis of semi-synthetic antibiotics in thermodynamically controlled water-cosolvent organic miscible apolar systems by using penicillin g acylase
04/1991
04/30/1991CA1283614C D-amino acid oxidase and method for isolation thereof
04/17/1991EP0422790A2 Recombinant DNA expression vectors and DNA compounds that encode acyltransferase activity of aspergillus
04/03/1991EP0420562A1 Deacetoxycephalosporin C hydroxylase
03/1991
03/28/1991CA2026262A1 Recombinant dna expression vectors and dna compounds that encode acyltransferase activity of aspergillus
02/1991
02/05/1991US4990444 γ-glutamyltranspeptidase, its preparation and its use
01/1991
01/23/1991EP0409521A2 Improved enzymatic oxidation of ceph C to glutaryl-7-amino-cephalosporanic acid
01/02/1991EP0405846A1 One-step cephalosporin C amidase enzyme, a gene encoding the same, and expression thereof in a suitable host
01/01/1991US4981789 One-step enzymatic conversion of cephalosporin C and derivatives to 7-aminocephalosporanic acid and derivatives
12/1990
12/27/1990CA2019625A1 One-step cephalosporin c amidase enzyme a gene encoding the same, and expression thereof in a prokaryotic host
10/1990
10/05/1990WO1990012110A1 Enzymatic production of 7-amino cephalosporanic acid
10/05/1990CA2049958A1 Enzymatic production of 7-amino cephalosporanic acid
08/1990
08/01/1990EP0379708A1 Fungi strain Tolypocladiam varium and process for obtaining complexes of antibiotic cyclosporin and/or its components
07/1990
07/04/1990EP0376226A1 Promoter of glyceraldehyde-3-phosphate dehydrogenase gene and its use
06/1990
06/28/1990CA2005861A1 Promoter of glyceraldehyde-3-phosphate dehydrogenase gene and its use
05/1990
05/02/1990EP0366354A2 Purified deacetoxycephalosporin C synthase
04/1990
04/18/1990EP0364275A2 D-amino acid oxidase
04/17/1990CA1267858A1 Microorganism immobilization
03/1990
03/13/1990US4908443 7-Beta-substituted 3-lower alkanoylacetoxy-methyl-7-alpha-methoxy-3-cephem-4-carboxylic acid
02/1990
02/06/1990US4898817 Microorganism immobilization
10/1989
10/11/1989EP0336511A2 Method of protection of the carboxy groups in the chemistry of beta-lactam compounds
07/1989
07/11/1989US4847200 Enzyme cyclization of dipeptides
06/1989
06/28/1989EP0322032A2 One-step enzymatic conversion of cephalosporin C and derivatives to 7-aminocephalosporanic acid and derivatives
06/28/1989EP0321849A2 Method for the enzymatic hydrolysis of alpha-aminoadipinyl monoamino compounds
12/1988
12/28/1988EP0296642A2 Biosynthesis of unnatural cephalosporins
12/28/1988EP0296641A2 Biosynthesis of unnatural cephalosporins
12/21/1988EP0295724A2 Biosynthesis of unnatural cephalosporins
12/20/1988CA1247029A1 Cephem compounds and their production
11/1988
11/23/1988CN88101644A Container using for storing an injector, which can be picked off, stored safely and be treated endly within it
11/09/1988EP0290136A2 7-Beta-substituted-3-lower alkanoylacetoxymethyl-7-alpha-methoxy-3-cephem-4-carboxylic acid and process for production of same
09/1988
09/27/1988US4774179 Process for preparing a 7-aminocephalosporanic acid compound
09/21/1988EP0283218A2 One-step enzymatic conversion of cephalosporin C and derivatives to 7-aminocephalosporanic acid and derivatives
09/07/1988EP0281391A1 Recombinant DNA expression vectors and DNA compounds that encode deacetoxycephalosporin C synthetase and deacetylcephalosporin C synthetase
08/1988
08/31/1988EP0280051A1 ACV synthetase
08/16/1988US4764606 Chemical intermediated
07/1988
07/27/1988EP0275901A2 Use of gamma-glutamyl-transpeptidase
06/1988
06/28/1988US4753881 Purified enzyme and process therefor
05/1988
05/25/1988EP0268343A2 Enzymatic process for 3-substituted cephalosporins
05/17/1988US4745061 Novel d-aminoacid transaminase and its use
03/1988
03/23/1988EP0260778A1 Enzymatic process for B-Lactams
03/16/1988EP0260072A2 Purified enzyme and process therefor
02/1988
02/02/1988US4723004 Antimicrobial agents
01/1988
01/14/1988WO1988000203A1 Higher alkyl pyrrolidone extractants for water soluble phenolic or carboxylic antibiotics
01/12/1988US4719287 Solvent extraction
09/1987
09/15/1987US4693977 Enzyme immobilization for producing cephalosporin antibiotics
08/1987
08/26/1987EP0233715A2 Isolation and expression of genes involved in the biosynthesis of beta-lactams
08/25/1987CA1225954A1 Process for the preparation of cephem compounds
08/04/1987CA1225052A1 Cephalosporins and their production
05/1987
05/19/1987US4667027 Cephem compounds and their production
04/1987
04/07/1987US4656262 7-methoxy cephalosporin derivative
04/01/1987EP0216636A2 Process for producing oganomycin E
03/1987
03/04/1987EP0212893A2 7-Formylaminocephalosporin compounds and microorganism and process for their production
02/1987
02/25/1987EP0211033A1 A d-amino acid oxidase and method for isolation thereof.
01/1987
01/14/1987CN85104867A Process for producing compounds of the kind of cephalosporin
08/1986
08/05/1986CA1209072A1 Production of cephalosporin c
07/1986
07/17/1986WO1986004087A1 A d-amino acid oxidase and method for isolation thereof
07/02/1986EP0186035A2 D-amino acid transaminase and its use
07/02/1986CA1206901A Biosynthesis of unnatural cephalosporins
05/1986
05/06/1986US4587333 Cephalosporins and their production
05/06/1986CA1204070A1 Biosynthesis of unnatural cephalosporins
04/1986
04/01/1986US4579818 Biosynthesis of unnatural cephalosporins
03/1986
03/05/1986EP0173206A1 Immobilized cells of Bacillus subtilis, process for their immobilization and use of the preparation for separating the 3-acetoxy group from 7-beta-acylamide cepholosporan acids
01/1986
01/15/1986EP0167651A1 Process for producing 3-cephem-4-carboxylic acid derivatives substituted in 3-position
11/1985
11/13/1985EP0160745A2 Cephem compounds and their production
08/1985
08/20/1985US4536476 From prokaryotic beta-lactam producing organism
08/13/1985US4535155 Adsorpiton on activated carbon and solvent extraction
08/07/1985EP0150378A2 Cephem compounds and their production
08/06/1985US4533632 Conversion to deacetyl cephalosporin c by an acetylesterase enzyme
06/1985
06/12/1985EP0144170A1 Biosynthesis of unnatural cephalosporins
05/1985
05/28/1985US4520101 Production of cephalosporin C
05/14/1985US4517299 Acetylesterases
04/1985
04/24/1985EP0138338A1 Penicillinamidase
04/17/1985EP0137365A2 Cephalosporins and their production
04/09/1985US4510246 Isolation of cyclase, epimerase and a ring expansion enzyme for producing unnatural cephalosporins
03/1985
03/19/1985US4506014 Plasmid pAC 1, a process for obtaining it and its use
12/1984
12/04/1984US4486549 Process for preparing an amino group-containing polyacrylonitrile polymer
11/1984
11/06/1984CA1177423A1 Enzymatic deesterification of cephalosporin methyl ester
10/1984
10/30/1984CA1177067A1 METHOD FOR CONCENTRATING .beta.-LACTAM ANTIBIOTIC SOLUTION
07/1984
07/10/1984US4459405 Chemical intermediates for 1-oxa-b-lactam antibiotics
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