Patents for C12P 35 - Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin (1,082) |
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03/18/1992 | EP0475652A2 Cephalosporin C acylase |
03/11/1992 | EP0474211A2 Process for the continuous transformation of cephalosporin derivatives in glutaryl-7-amino-cephalosporin derivatives |
03/10/1992 | CA1297056C Cephem compounds and their production |
03/06/1992 | CA2050615A1 Process for the continuous conversion of cephalosporin derivatives into glutaryl-7-aminocephalosporanic acid derivatives |
03/04/1992 | EP0473008A2 Improved process for preparing penicillins and cephalosporins |
02/05/1992 | EP0469919A2 A process for the enzymatic preparation of 7-aminocephalosporanic acid |
01/23/1992 | WO1992001061A1 PROCESS FOR PREPARATION OF β-LACTAMS |
01/22/1992 | CN1058045A Cephalosporin acetylhydrolase gene and protein encoded by said gene |
01/21/1992 | US5082772 Process for preparing deacetylcephalosporin c |
01/07/1992 | US5079146 Penicillinacylase is used to remove ester protecting group |
12/27/1991 | EP0462674A1 An oxido reductase enzyme system obtainable from P. chrysogenum, the set of genes encoding the same and the use of oxido reductase enzyme systems or genes encoding the same for increasing antibiotic production |
12/26/1991 | WO1991019788A1 An oxido reductase enzyme system obtainable from p. chrysogenum, the set of genes encoding the same and the use of oxido reductase enzyme systems or genes encoding the same for increasing antibiotic production |
12/04/1991 | EP0458932A1 Method for the synthesis of semi-synthetic antibiotics in thermodynamically controlled water-cosolvent organic miscible apolar systems by using penicillin g acylase |
10/30/1991 | EP0454478A1 Cephalosporin acetylhydrolase gene and protein encoded by said gene |
10/30/1991 | CN1014528B Process for producing compounds of the kind of cephalosporin |
10/09/1991 | EP0450758A1 An acetyltransferase gene-containing DNA |
09/25/1991 | EP0448180A2 A method of modulating the production of secondary metabolites |
09/11/1991 | EP0445868A1 A method for influencing beta-lactam antibiotic production and for isolation of large quantities of ACV synthetase |
09/04/1991 | EP0444758A1 Method for modification of ACV synthetase and use of the modified enzyme for production of beta-lactam antibiotics |
07/17/1991 | EP0211033B1 A d-amino acid oxidase and method for isolation thereof |
07/10/1991 | EP0436355A2 Process for producing 7-aminocephem compound or salts thereof |
06/27/1991 | WO1991009136A1 Method for the synthesis of semi-synthetic antibiotics in thermodynamically controlled water-cosolvent organic miscible apolar systems by using penicillin g acylase |
04/30/1991 | CA1283614C D-amino acid oxidase and method for isolation thereof |
04/17/1991 | EP0422790A2 Recombinant DNA expression vectors and DNA compounds that encode acyltransferase activity of aspergillus |
04/03/1991 | EP0420562A1 Deacetoxycephalosporin C hydroxylase |
03/28/1991 | CA2026262A1 Recombinant dna expression vectors and dna compounds that encode acyltransferase activity of aspergillus |
02/05/1991 | US4990444 γ-glutamyltranspeptidase, its preparation and its use |
01/23/1991 | EP0409521A2 Improved enzymatic oxidation of ceph C to glutaryl-7-amino-cephalosporanic acid |
01/02/1991 | EP0405846A1 One-step cephalosporin C amidase enzyme, a gene encoding the same, and expression thereof in a suitable host |
01/01/1991 | US4981789 One-step enzymatic conversion of cephalosporin C and derivatives to 7-aminocephalosporanic acid and derivatives |
12/27/1990 | CA2019625A1 One-step cephalosporin c amidase enzyme a gene encoding the same, and expression thereof in a prokaryotic host |
10/05/1990 | WO1990012110A1 Enzymatic production of 7-amino cephalosporanic acid |
10/05/1990 | CA2049958A1 Enzymatic production of 7-amino cephalosporanic acid |
08/01/1990 | EP0379708A1 Fungi strain Tolypocladiam varium and process for obtaining complexes of antibiotic cyclosporin and/or its components |
07/04/1990 | EP0376226A1 Promoter of glyceraldehyde-3-phosphate dehydrogenase gene and its use |
06/28/1990 | CA2005861A1 Promoter of glyceraldehyde-3-phosphate dehydrogenase gene and its use |
05/02/1990 | EP0366354A2 Purified deacetoxycephalosporin C synthase |
04/18/1990 | EP0364275A2 D-amino acid oxidase |
04/17/1990 | CA1267858A1 Microorganism immobilization |
03/13/1990 | US4908443 7-Beta-substituted 3-lower alkanoylacetoxy-methyl-7-alpha-methoxy-3-cephem-4-carboxylic acid |
02/06/1990 | US4898817 Microorganism immobilization |
10/11/1989 | EP0336511A2 Method of protection of the carboxy groups in the chemistry of beta-lactam compounds |
07/11/1989 | US4847200 Enzyme cyclization of dipeptides |
06/28/1989 | EP0322032A2 One-step enzymatic conversion of cephalosporin C and derivatives to 7-aminocephalosporanic acid and derivatives |
06/28/1989 | EP0321849A2 Method for the enzymatic hydrolysis of alpha-aminoadipinyl monoamino compounds |
12/28/1988 | EP0296642A2 Biosynthesis of unnatural cephalosporins |
12/28/1988 | EP0296641A2 Biosynthesis of unnatural cephalosporins |
12/21/1988 | EP0295724A2 Biosynthesis of unnatural cephalosporins |
12/20/1988 | CA1247029A1 Cephem compounds and their production |
11/23/1988 | CN88101644A Container using for storing an injector, which can be picked off, stored safely and be treated endly within it |
11/09/1988 | EP0290136A2 7-Beta-substituted-3-lower alkanoylacetoxymethyl-7-alpha-methoxy-3-cephem-4-carboxylic acid and process for production of same |
09/27/1988 | US4774179 Process for preparing a 7-aminocephalosporanic acid compound |
09/21/1988 | EP0283218A2 One-step enzymatic conversion of cephalosporin C and derivatives to 7-aminocephalosporanic acid and derivatives |
09/07/1988 | EP0281391A1 Recombinant DNA expression vectors and DNA compounds that encode deacetoxycephalosporin C synthetase and deacetylcephalosporin C synthetase |
08/31/1988 | EP0280051A1 ACV synthetase |
08/16/1988 | US4764606 Chemical intermediated |
07/27/1988 | EP0275901A2 Use of gamma-glutamyl-transpeptidase |
06/28/1988 | US4753881 Purified enzyme and process therefor |
05/25/1988 | EP0268343A2 Enzymatic process for 3-substituted cephalosporins |
05/17/1988 | US4745061 Novel d-aminoacid transaminase and its use |
03/23/1988 | EP0260778A1 Enzymatic process for B-Lactams |
03/16/1988 | EP0260072A2 Purified enzyme and process therefor |
02/02/1988 | US4723004 Antimicrobial agents |
01/14/1988 | WO1988000203A1 Higher alkyl pyrrolidone extractants for water soluble phenolic or carboxylic antibiotics |
01/12/1988 | US4719287 Solvent extraction |
09/15/1987 | US4693977 Enzyme immobilization for producing cephalosporin antibiotics |
08/26/1987 | EP0233715A2 Isolation and expression of genes involved in the biosynthesis of beta-lactams |
08/25/1987 | CA1225954A1 Process for the preparation of cephem compounds |
08/04/1987 | CA1225052A1 Cephalosporins and their production |
05/19/1987 | US4667027 Cephem compounds and their production |
04/07/1987 | US4656262 7-methoxy cephalosporin derivative |
04/01/1987 | EP0216636A2 Process for producing oganomycin E |
03/04/1987 | EP0212893A2 7-Formylaminocephalosporin compounds and microorganism and process for their production |
02/25/1987 | EP0211033A1 A d-amino acid oxidase and method for isolation thereof. |
01/14/1987 | CN85104867A Process for producing compounds of the kind of cephalosporin |
08/05/1986 | CA1209072A1 Production of cephalosporin c |
07/17/1986 | WO1986004087A1 A d-amino acid oxidase and method for isolation thereof |
07/02/1986 | EP0186035A2 D-amino acid transaminase and its use |
07/02/1986 | CA1206901A Biosynthesis of unnatural cephalosporins |
05/06/1986 | US4587333 Cephalosporins and their production |
05/06/1986 | CA1204070A1 Biosynthesis of unnatural cephalosporins |
04/01/1986 | US4579818 Biosynthesis of unnatural cephalosporins |
03/05/1986 | EP0173206A1 Immobilized cells of Bacillus subtilis, process for their immobilization and use of the preparation for separating the 3-acetoxy group from 7-beta-acylamide cepholosporan acids |
01/15/1986 | EP0167651A1 Process for producing 3-cephem-4-carboxylic acid derivatives substituted in 3-position |
11/13/1985 | EP0160745A2 Cephem compounds and their production |
08/20/1985 | US4536476 From prokaryotic beta-lactam producing organism |
08/13/1985 | US4535155 Adsorpiton on activated carbon and solvent extraction |
08/07/1985 | EP0150378A2 Cephem compounds and their production |
08/06/1985 | US4533632 Conversion to deacetyl cephalosporin c by an acetylesterase enzyme |
06/12/1985 | EP0144170A1 Biosynthesis of unnatural cephalosporins |
05/28/1985 | US4520101 Production of cephalosporin C |
05/14/1985 | US4517299 Acetylesterases |
04/24/1985 | EP0138338A1 Penicillinamidase |
04/17/1985 | EP0137365A2 Cephalosporins and their production |
04/09/1985 | US4510246 Isolation of cyclase, epimerase and a ring expansion enzyme for producing unnatural cephalosporins |
03/19/1985 | US4506014 Plasmid pAC 1, a process for obtaining it and its use |
12/04/1984 | US4486549 Process for preparing an amino group-containing polyacrylonitrile polymer |
11/06/1984 | CA1177423A1 Enzymatic deesterification of cephalosporin methyl ester |
10/30/1984 | CA1177067A1 METHOD FOR CONCENTRATING .beta.-LACTAM ANTIBIOTIC SOLUTION |
07/10/1984 | US4459405 Chemical intermediates for 1-oxa-b-lactam antibiotics |