Patents for C12P 35 - Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin (1,082)
06/2009
06/03/2009EP2064331A1 Process for preparation of optically active n-protected 3 -aminopyrrolidine or optically active n-protected 3-aminopiperidine and the corresponding ketones by optical resolution of the racemic amine mixtures employing a bacterial omega-transaminase
05/2009
05/13/2009CN101429538A Process for producing 7-alpha-methoxy-3-deacetyled cefoxitin benzathine
04/2009
04/29/2009CN101418331A Process for producing 7-methoxy-3-desacetylcefalotin
04/15/2009EP2048240A2 Process for producing 7-methoxy-3-desacetylcefalotin
04/02/2009WO2009013611A3 Modified esterase and its applications
03/2009
03/19/2009US20090075327 Methods for improving secondary metabolite production in fungi
03/18/2009CN101389635A Improved cephalosporin production
02/2009
02/05/2009WO2009016642A1 Process for the preparation of immobilized recombinant penicillin acylase catalyst from achromobacter sp. ccm 4824 expressed in e. coli bl 21 ccm 7394 and its use for the synthesis of beta-lactam antibiotics
01/2009
01/28/2009CN101353660A Improved in vivo production of cephalosporins
01/07/2009CN100448996C Fermentation of pentose sugars
12/2008
12/24/2008EP1468093B1 Fermentation of pentose sugars
12/10/2008CN101319246A Process for preparing cefixime
11/2008
11/05/2008EP1987041A1 Improved cephalosporin production
10/2008
10/15/2008CN101287827A Amidases, nucleic acids encoding them and methods for making and using them
10/08/2008CN101280022A Fused protein of D-aminoacid oxidase, carrier and application thereof
09/2008
09/18/2008WO2008110527A1 Process for the preparation of beta-lactam compounds
08/2008
08/14/2008US20080193969 Using microorganismal bioreactor to ferment oxygen-binding protein
08/13/2008CN101240285A Cephalosporin C acrylase and its vector and application
08/06/2008EP1953230A1 Improved in vivo production of cephalosporins
07/2008
07/30/2008EP0961825B1 Mutant penicillin g acylases
07/15/2008US7399624 Recombinant hydrolase for use in the preparation of 7-amino-cephalosporanic acid; bioreactors
05/2008
05/28/2008EP1925670A1 Escherichia coli expression vector and the uses thereof
05/28/2008EP1925663A1 Two-steps enzyme method for preparing 7-aminocephalosporanic acid
05/28/2008CN100390285C Improved i(in vivo) production of cephalosporins
05/07/2008CN100386440C Use of recommbined D-amino acid oxidase
04/2008
04/29/2008US7365431 Semiconductor device having multilayer structure and method for manufacturing thereof
03/2008
03/19/2008EP0920527B1 SYNTHESIS OF beta-LACTAM ANTIBACTERIALS USING SOLUBLE SIDE CHAIN ESTERS AND ENZYME ACYLASE
03/05/2008CN100372931C Process for immobilization of glutaryl-7-amino cephalosporanic acid acylase
02/2008
02/28/2008US20080050771 Process for the Synthesis of Cefaclor
02/27/2008CN101130804A Method for enzymatically synthesizing beta-lactam antibiotic in mixed system of water and organic medium
02/27/2008CN101130803A Method for enzymatically synthesizing beta-lactam antibiotic in organic solvent
02/13/2008EP1078069B1 Improved in vivo production of cephalosporins
01/2008
01/17/2008US20080014620 Fermentation of pentose sugars
01/02/2008CN101098963A Production of beta-lactam antibiotics by genetically modified non-naturally producing microorganisms
12/2007
12/21/2007WO2004069848A3 Amidases, nucleic acids encoding them and methods for making and using them
12/21/2007WO2003064613A3 Amidases, nucleic acids encoding them and methods for making and using them
12/19/2007CN101090978A Process for the synthesis of cefaclor
12/06/2007WO2003076640A3 A process for the preparation of cephalosporan acid derivatives from cephalosporin c
11/2007
11/28/2007CN100351386C Production of valuable compound by using chemically defined culture medium and adopting industrial scal fermentation process
11/20/2007CA2263653C Energy absorbing elastomers
09/2007
09/19/2007CN101040043A Mutant expandases
09/13/2007WO2007038169A3 Multi-valent guanidinium compounds for molecular translocation across cellular membranes and epithelial tissues
09/12/2007EP1831390A2 Process for the synthesis of cefaclor
09/06/2007US20070207519 Cephalosporin C Acylase Mutant and Method for Preparing 7-ACA Using Same
09/04/2007US7264943 Preparing penicillin amidase coated beads comprised of cephalexin via inverse bead polymerization; contacting 7-aminodeacetoxycephalosporanic acid,D-phenylglycinamide and penicillin amidase in aqueous solution
08/2007
08/30/2007WO2007096419A1 Improved cephalosporin production
08/22/2007EP1819813A2 Production of beta-lactam antibiotics by genetically modified non-naturally producing microorganisms
08/09/2007US20070184513 Substrates for beta-lactamase and uses thereof
07/2007
07/10/2007US7241588 Method for producing novel β-lactam antibiotic from protoplast fusion strain
06/2007
06/27/2007EP1799817A2 Mutant expandases
06/12/2007US7229784 By fungi through genetic manipulation of such fungi
05/2007
05/10/2007WO2007051355A1 The use of recombinant d-amino acid oxidase
05/09/2007EP1656450A4 Cephalosporin c acylase mutant and method for preparing 7-aca using same
05/01/2007US7211377 Using electromagnetic radiation to detect and quantify viable bacteria, fungi, protozoa and rickettsiae, spores on non-living surfaces, in air and in liquids; detecting microorganisms in food
04/2007
04/26/2007US20070093465 Cephem compound
04/26/2007US20070092955 Fermentative production of lipids on an industrial scale using chemically defined media
04/18/2007EP1226266B1 Method for enhancing secretion of beta-lactam compounds
04/12/2007WO2006069984A3 Process for the synthesis of cefaclor
03/2007
03/27/2007US7195892 Acylase gene
03/07/2007CN1303217C Process for the preparation of a beta-lactam nucleus and the application thereof
03/01/2007WO2007023369A1 Modified expandase-hydroxylase and its applications
02/2007
02/15/2007WO2007016861A1 Two-steps enzyme method for preparing 7-aminocephalosporanic acid
02/15/2007WO2007016860A1 Escherichia coli expression vector and the uses thereof
02/14/2007CN1912130A Two-step enzyme method for preparing 7-aminocephalosporanic acid
01/2007
01/03/2007CN1293200C Method for producing cephalexin
01/02/2007US7157575 Measuring gene expression
12/2006
12/28/2006US20060292665 Glutaryl amidases and their uses
12/27/2006CN1292064C Microorganism strain and method for converting cephalosporin C into deacetylate cephalosporin C by using same
12/20/2006CN1291033C Crystallizing method for 7-amino cephalo phytanic acid
11/2006
11/16/2006US20060259993 Amidases, nucleic acids encoding them and methods for making and using them
10/2006
10/19/2006WO2006040313A3 Mutant expandases
10/18/2006CN1280423C Production method of 7-amino cephalosporanic acid
10/11/2006CN1844383A Process for immobilization of glutaryl-7-amino cephalosporanic acid acylase
10/04/2006CN1840687A Method for fermentation preparation of 7-amino-3-deacetoxy cephalosporanic acid
09/2006
09/20/2006CN1836044A Cephalosporin c(CPC) acylase mutant having improved reactivity at cpc substrate and improved resistance to 7-aca productand method for preparing 7-aca using same
08/2006
08/30/2006CN1272445C Method for purifying cephalosporin C broth using adsorbent
08/24/2006US20060189802 Reacting 7-aminodesacetoxy cephalosporanic acid (7-ADCA) with D-dihydrophenylglycine in activated form (DHa) in the presence of acylase
08/23/2006CN1271208C Process of producing beta-lactam antibiotics applying microorganisms with increased ligase activity
08/16/2006EP1690945A2 Fermentative production of valuable compounds on an industrial scale using chemically defined media
08/16/2006EP1690593A1 Use of aerogels as adsorption material
08/03/2006WO2006061425A3 Production of beta-lactam antibiotics by genetically modified non-naturally producing microorganisms
08/02/2006CN1813069A Process for the preparation of cephradine
07/2006
07/27/2006US20060166308 Stereoisomerically enriched beta-lactams using candida antarctica
07/26/2006CN1807581A Engineered bacteria producing penicillium chrysogenum and its uses in producing 7-amido -3-deacetoxy cefaeicosanoic acid
06/2006
06/15/2006WO2006061425A2 Production of beta-lactam antibiotics by genetically modified non-naturally producing microorganisms
06/15/2006US20060127972 In vivo production of cephalosporins
06/15/2006US20060127971 Use of bioreactor for the enzymatic synthesis of beta -lactam antibiotics, which have a primary matrix for immobilization involved by a secondary matrix, which is able to preserve 100% of the catalyst physical integrity
05/2006
05/31/2006EP0861321B1 Phosphopantetheinyl transferases and uses thereof
05/24/2006EP0970236B1 Fermentative production of valuable compounds on an industrial scale using chemically defined media
05/24/2006CN1257269C Method for producing 7-amino cephalosporanic acid and its specific recombinase
05/18/2006US20060105424 Nucleic acids which code for protein from Acremonium chrysogenum; host cells
05/17/2006EP1656450A1 Cephalosporin c acylase mutant and method for preparing 7-aca using same
04/2006
04/20/2006WO2006040313A2 Mutant expandases
04/13/2006DE19924632B4 Verfahren zur Verzögerung der Desaktivierung von Glutarylamidase während einer Enzymkatalyse Method of delaying the deactivation of glutaryl amidase during enzyme catalysis
04/06/2006WO2005054452A3 Glutaryl amidases and their uses
04/05/2006EP1641933A2 Process for the preparation of cephradine
04/04/2006CA2128570C High density high surface area adsorbents
03/2006
03/29/2006EP0975405B1 Use of aerogels as adsorption agents
03/08/2006CN1244400C Use of aerogels as adsorption agents
02/2006
02/17/2006CA2573130A1 Isolated fungal promoters and gene transcription terminators and methods of protein and chemical production in a fungus
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