C12P 35 - Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin

Patents for C12P 35 - Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin (1,082)
02/2015
02/11/2015	CN103184182B 青霉素酰化酶、其高产菌株及应用 Penicillin, the high-yield strains and application
01/2015
01/29/2015	US20150031076 Transformed cells that ferment pentose sugars and methods of their use
01/21/2015	CN103160561B 一种用于发酵生产头孢菌素c的方法 A fermentation method for cephalosporin c
01/14/2015	CN104278071A 头孢菌素c的提取方法 Extraction of cephalosporin c
01/07/2015	CN104263792A 制备头孢菌素c的发酵方法和该方法中使用的发酵培养基 Fermenting the fermentation medium was prepared cephalosporin c and the method used
12/2014
12/25/2014	US20140377813 Pentose fermenting microorganisms
12/10/2014	CN103014114B 一种酶法制备7-氨基头孢烷酸的方法 One kind of Enzymatic Preparation of 7-ACA method
11/2014
11/20/2014	US20140342396 Fermentative production of lipids on an industrial scale using chemically defined media
08/2014
08/06/2014	CN102925423B 一种突变头孢菌素c酰化酶 A cephalosporin acylase mutant c
07/2014
07/23/2014	CN103937764A 头孢菌素类抗生素原料物质（7-aca）生产用变异酶 Cephalosporins raw material (7-aca) enzyme production variability
07/16/2014	CN102952787B 一种乙酰木聚糖酯酶及其应用 An acetylated xylan esterase and its Applications
07/16/2014	CN101631872B 制备β-内酰胺化合物的工艺 Process for preparing the compound β- lactam
07/09/2014	CN102505035B 一种3-去乙酰基-7-氨基头孢烷酸的制备工艺 Preparation of 3-desacetyl-7-aminocephalosporanic acid
07/02/2014	CN103060298B 一种头孢菌素c酰化酶突变体及其编码基因与应用 Body and its coding gene and Application of a cephalosporin acylase mutant c
06/2014
06/25/2014	CN102827912B 两酶一步法制备医药中间体d-7-aca的工艺 Pharmaceutical intermediates d-7-aca-step process for the preparation of the two enzymes
06/18/2014	CN103865911A Penicillin G acylation enzyme mutant, and application thereof in synthesis of cephalosporin antibiotics
06/12/2014	US20140162312 Pentose sugar fermenting cell
06/04/2014	CN103834631A Penicillin G acylase mutant, and coding gene and application thereof
06/04/2014	CN103834607A Method for producing l-amino acids from d-amino acids
06/04/2014	CN102925525B Method for producing cefoxitin acid
05/2014
05/28/2014	CN101040043B 突变型扩环酶 Mutant expandase enzyme
05/21/2014	CN103805671A 一种制备头孢氨苄的方法 A process for the preparation of cephalexin
04/2014
04/30/2014	EP2723882A1 Process for preparing 3'-thiosubstituted cephalosporins employing a penicillin g acylase
04/30/2014	EP2723881A2 Novel crystalline cefoperazone intermediate
04/30/2014	CN103757085A Cefaclor and synthetic method thereof
04/02/2014	CN103695522A Preparation method of cefditoren pivoxil cephalosporins intermediate
04/02/2014	CN103695447A Novel lactam antibiotic synthetase, coding gene and application thereof
03/2014
03/19/2014	CN103642780A Mutant penicillin G acylases
03/12/2014	CN103635586A Crystalline cefoperazone intermediate, preparing method and application thereof
03/12/2014	CN103635585A Process for preparing 3'-thiosubstituted cephalosporins employing a penicillin G acylase
03/12/2014	CN103627773A Fermentation technology of cephalosporin
02/2014
02/12/2014	CN103571907A Separation and purification method for cefaclor by enzymatic synthesis
02/05/2014	CN103555807A Method for preparing 7-ACA (aminocephalosporanic acid) and obtaining alpha-aminoadipic acid by one-step enzymatic reaction
01/2014
01/22/2014	CN103525893A Method of preparing 7-amino-cephalsporanic acid under catalysis of cephalosporin acylase
01/22/2014	CN103525800A Preparation method and application of polyvinyl alcohol immobilized acylase
01/22/2014	CN103525796A Recombinase with activity of glutaryl-7-aminocephalosporanic acid acylase and D-amino acid oxidase as well as preparation method and application thereof
01/01/2014	EP2679686A1 Nucleic acid molecule encoding xylose isomerase and xylose isomerase encoded thereof
12/2013
12/25/2013	CN101525603B Immobilized alpha-amino-acid ester hydrolase, preparation and application thereof
12/18/2013	CN103451259A Method for enzymatic synthesis of cefprozil in recyclable aqueous two-phase system by using immobilized penicillin acylase
12/04/2013	CN103421727A Genetically engineered bacterium for converting cephalosporin C and preparation method thereof
12/04/2013	CN102719473B Acremonium-chrysogenum engineering bacterium and construction method thereof
11/2013
11/27/2013	CN102605033B Method for preparing cefazolin intermediate TDA
11/19/2013	US8586336 Nucleic acid molecule encoding xylose isomerase and xylose isomerase encoded by the nucleic acid molecule
10/2013
10/30/2013	CN103374595A Method for preparing beta-lactam derivative through enzymatic reaction
10/30/2013	CN103374558A Acylase for producing 7-ACA (Aminocephalosporanic acid) by splitting CPC (Cephalosporin C) by utilizing a one-step method and polynucleotide encoding same
10/23/2013	CN102264904B Mutant penicillin G acylases
10/16/2013	CN102808013B Method for preparing cephalosporin C through fermentation
10/16/2013	CN102808012B Method for preparing cephalosporin C through fermentation, and cephalosporium acremonium fermentation medium
10/16/2013	CN102808011B Fermentation method for cephalosporin C
10/16/2013	CN102533920B Method for reducing decomposition of cephalosporin C
10/15/2013	US8557978 Cross-linked glycopeptide-cephalosporin antibiotics
09/2013
09/11/2013	CN103289908A Metabolic engineering of arabinose- fermenting yeast cells
09/11/2013	CN102703559B Preparation method for 7 beta-amino-3-[4-(1-methyl-4-pyridinium)-2-thiazole sulfenyl]-3-cephem-4-carboxylate acidification matter
08/2013
08/28/2013	CN101970654B Stable biocatalysts of penicillin acylase as gel aggregates and the process of manufacture thereof
08/28/2013	CN101802212B Process for the preparation of immobilized recombinant penicillin acylase catalyst from Achromobacter sp. CCM 4824 expressed in E. coli BL 21 CCM 7394 and its use for the synthesis of beta-lactam antibiotics
08/08/2013	WO2013113646A1 Mbth-like proteins in the production of semi synthetic antibiotics
07/2013
07/18/2013	WO2013105030A1 Mutated cephalosporin hydroxylase and its application in deacetylcephalosporanic acid synthesis
07/03/2013	CN103184182A Penicillin acylase, as well as high-yield strain and application thereof
06/2013
06/19/2013	CN103160561A Method for fermentation production of cephalosporin C
06/04/2013	CA2474033C Fermentation of pentose sugars
05/2013
05/08/2013	CN102653726B Colibacillus containing alpha-amino-acid ester hydrolase gene
05/01/2013	EP2585608A1 Air bubble fermentation process
04/2013
04/24/2013	CN103060417A Preparation method of 7-amino-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
04/24/2013	CN103060298A Cephalosporin C acylase mutant as well as coding gene and application thereof
04/04/2013	US20130084617 Transformed cells that ferment-pentose sugars and methods of their use
04/03/2013	CN103014114A Method for preparing 7-aminocephalosporanic acid via enzymic method
03/2013
03/28/2013	WO2012175587A3 Crystalline cefoperazone intermediate, process for its preparation and pharmaceutical use thereof
03/27/2013	CN103003439A Air bubble fermentation process
03/27/2013	CN102321603B Cephalosporin acylase mutant and encoding gene and application thereof
03/20/2013	CN102978192A Mutant cephalosporin C acylase, method for preparing same and method for converting 7-aminocephalosporin acid (ACA)
03/13/2013	CN102533695B Alpha-amino ester hydrolase mutant
03/07/2013	US20130059331 Cell suitable for fermentation of a mixed sugar composition
03/06/2013	CN102952787A Acetylxylan esterase and application thereof
03/06/2013	CN102220403B Method for preparing 7-ACCA
03/06/2013	CN101389635B Improved cephalosporin production
02/2013
02/20/2013	CN102936614A Synthesis method of 7-alpha-methoxy-3-deacetylcephalothin benzathine
02/14/2013	US20130040297 Process for the production of cells which are capable of converting arabinose
02/13/2013	CN102925525A Method for producing cefoxitin acid
02/13/2013	CN102925423A Mutated cephalosporin C acylase
02/05/2013	US8367396 Transformed yeast cells that ferment pentose sugars
01/2013
01/16/2013	CN102876766A Fermentation process of cephalosporin C
12/2012
12/27/2012	WO2012175587A2 Novel crystalline cefoperazone intermediate
12/27/2012	WO2012175585A1 Process for preparing 3'-thiosubstituted cephalosporins employing a penicillin g acylase
12/26/2012	CN102030762B Preparation method of cefprozil
12/19/2012	CN102827912A Technology for preparing medicine intermediate D-7-ACA by two enzyme carriers one-step method
12/05/2012	CN102808013A Method for preparing cephalosporin C through fermentation
12/05/2012	CN102808012A Method for preparing cephalosporin C through fermentation, and cephalosporium acremonium fermentation medium
12/05/2012	CN102808011A Fermentation method for cephalosporin C
10/2012
10/31/2012	CN102757999A Fermentation medium for production of 7-aminocephalosporanic acid and fermentation method of fermentation medium
10/24/2012	EP2513327A2 Production process for cephradine
10/10/2012	CN102719473A Acremonium-chrysogenum engineering bacterium and construction method thereof
10/10/2012	CN102174549B Nucleic acid molecules for coding xylose isomerase and xylose isomerase coded by same
10/03/2012	CN102703559A Preparation method for 7 beta-amino-3-[4-(1-methyl-4-pyridinium)-2-thiazole sulfenyl]-3-cephem-4-carboxylate acidification matter
09/2012
09/06/2012	US20120225452 nucleic acid molecule for encoding xylose isomerase and xylose isomerase encoded by the nucleic acid molecule
09/06/2012	US20120225451 Metabolic engineering of xylose-fermenting eukaryotic cells
09/05/2012	CN102656274A Production process for cephradine
09/05/2012	CN102653726A Colibacillus containing alpha-amino-acid ester hydrolase gene
08/2012
08/30/2012	WO2012113120A1 Nucleic acid molecule encoding xylose isomerase and xylose isomerase encoded thereof
08/16/2012	US20120208231 Metabolic engineering of arabinose-fermenting yeast cells
08/01/2012	EP2173892B8 Process for the preparation of immobilised recombinant Penicillin Acylase biocatalyst from Achromobacter sp CCM 4824 expressed in E. coli BL21 CCM 7394 and its use for the synthesis of beta-lactam antiobiotics

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