Patents
Patents for C07D 401 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom (107,979)
01/2005
01/05/2005EP1493735A1 Pyrimidine derivatives useful as selective cox-2 inhibitors
01/05/2005EP1492787A2 (condensed) pyrimidone and (condensed) pyridone compounds, processes for their preparation, and pharmaceutical compositions containing them
01/05/2005EP1492786A1 Pyridinoylpiperidines as 5-ht1f agonists
01/05/2005EP1492785A1 New compounds
01/05/2005EP1492784A2 Substituted 2,3-diphenyl pyridines
01/05/2005EP1492777A1 Thiazolidine-4-carbonitriles and analogues and their use as dipeptidyl-peptidase inhibitors
01/05/2005EP1492775A2 Oxo-azabicyclic compounds
01/05/2005EP1492773A2 4-(heterocyclyl)-benzenesulfoximine compounds for the treatment of inflammation
01/05/2005EP1492772A1 Farnesyl protein transferase inhibitors as antitumor agents
01/05/2005EP1492765A2 Novel gamma secretase inhibitors
01/05/2005EP1492571A2 Radiolabelled quinoline and quinolinone derivatives and their use as metabotropic glutamate receptor ligands
01/05/2005EP1492568A1 Cancer treatment method comprising administration of an erb-family inhibitor and a raf and/or ras inhibitor
01/05/2005EP1492536A1 4-(n-phenylamino)-quinazolines / quinolines as tyrosine kinase inhibitors
01/05/2005EP1492533A1 N-substituted pyridinone and pyrimidinone derivatives for use as lp-pla2 inhibitors in the treatment of artherosclerosis
01/05/2005EP1492526A2 Improved prodrugs of cc-1065 analogs
01/05/2005EP1492487A2 Mitotic kinesin inhibitors
01/05/2005EP1274687B1 1,2,3,4- tetrahydroisoquinoline derivatives
01/05/2005EP1226126B1 Pyrimidine derivatives
01/05/2005EP1015449B1 (hetero)aryl-sulfonamide derivatives, their preparation and their use as factor xa inhibitors
01/05/2005EP1006110B8 Derivatives of acyl-piperazinil-pyrimidins, preparation thereof and application as medicaments
01/05/2005DE10328036A1 New N-benzyl-anthranilic acid (hetero)arylamide derivatives and analogs, are tyrosine kinase KDR and FLT inhibitors and angiogenesis inhibitors, useful e.g. for treating tumors, psoriasis or restenosis
01/05/2005DE10327428A1 Preparation of pyrrolidine-1,2-dicarboxanilide derivatives for use as factor Xa inhibiting antithrombotic agents, comprises reacting pyrrolidine-2-carboxylic acid with phenyl isocyanate then aniline derivative
01/05/2005CN1561393A Inhibitors of glycogen synthase kinase-3 (GSK-3) for treating glaucoma
01/05/2005CN1561340A Novel 1, 2, 4-triazole compound
01/05/2005CN1561339A Process for preparing pyridyl-alkylsulfonyl pyrazole derivatives
01/05/2005CN1561246A Compositions of cyclooxygenase-2 selective inhibitors and radiation for inhibition or prevention of cardiovascular disease
01/05/2005CN1561212A Benzimidazolidinone derivatives as muscarinic agents
01/05/2005CN1561211A Nociceptin analogs
01/05/2005CN1560052A Derivant of electrophosphorescence 1, 8-naphthimide and luminous ligand thereof
01/05/2005CN1560051A 取代吡唑化合物 A substituted pyrazole compound
01/05/2005CN1560050A Derivative of phenylamide pyrimidine and application thereof
01/05/2005CN1560041A Compounds and methods for treatment of asthma, allergy and inflammatory disorders
01/05/2005CN1183128C N-(heterocyclic)-benzene or pyridine sulphozmides as antithrombotic agents and anticoagulants
01/05/2005CN1183127C Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
01/05/2005CN1183119C Arylpiperzines as metalloproteinase inhibiting agents (MMP) and their use
01/05/2005CN1183116C Substituted isoquinoline derivatives and pharmaceutical composition containing them, its preparation method and use
01/05/2005CN1183115C 5-amino-8-methoxy quinolone carboxylic acid derivatives and its preparation
01/05/2005CN1183114C Quinoline derivatives and quinazoline derivatives
01/05/2005CN1183113C Tri-aryl acid derivatives as PPAR receptor ligands
01/04/2005US6838565 Factor x inhibitor; anticoagulants
01/04/2005US6838564 Substituted pyridine herbicides
01/04/2005US6838559 Such as 2-((6-(((4-(3,4-dimethoxyphenyl)methyl)amino)-7-ethyl-7H-purin-2-yl)amino) -4,5-methyl-N-phenyl-5-thiazole-carboxamide for treatment of lymphocyte mediated diseases such as transplant rejection and graft versus host disease
01/04/2005US6838479 Amidine inhibitors of serine proteases
01/04/2005US6838478 Use as anticoagulants; competitive inhibitors of thrombin; for example, 1-(phenyl-2-hydroxyethane-1,1-diylcarbonyl), 2-((4-amidinophenyl)-alkylaminocarbonyl)azetidine
01/04/2005US6838476 Imidazoles with anti-inflammatory activity
01/04/2005US6838471 Inhibition of inflammatory cytokine production by cholinergic agonists and vagus nerve stimulation
01/04/2005US6838468 4-(phenyl-piperdin-4-ylidene methyl)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
01/04/2005US6838467 Dosing regimen
01/04/2005US6838466 Compounds for the treatment of inflammatory disorders
01/04/2005US6838465 N-acyltetrahydroisoquinoline derivatives
01/04/2005US6838464 Inhibitor of cyclin-dependent kinase
01/04/2005US6838458 5-(alkylidene-cycloalkyl)-and 5-(alkylidene-heterocyclyl)-pyrazoles
01/04/2005US6838455 Inhibiting beta -amyloid peptide release and/or its synthesis in a cell by administering deoxyamino acid compound
01/04/2005US6838454 Carboxylic acid substituted heterocycles, derivatives thereof and methods of use
01/04/2005US6837908 For dyeing hair; efficiency
01/04/2005CA2350854C 1,4-dihydropyridine derivatives and methods of producing the same
01/04/2005CA2340999C 5-arylindole derivatives
01/04/2005CA2293834C Substituted naphthopyrans
01/04/2005CA2186015C Nicotinic acid derivatives and herbicides
01/04/2005CA2124696C Vasopressin antagonist and oxytocin antagonist
01/04/2005CA2116632C Process for the preparation of 6-alkyl-4-(pyridin-3-yl-methyleneamino)-4,5-dihydro-1,2,4-triazin-3(2h)-one
12/2004
12/30/2004US20040267028 Such as 2-amino-1-(2-chlorophenyl)-5-(4-chlorophenyl)-N-cyclohexyl-1H-pyrrole-3-carboxamide hydrochloride
12/30/2004US20040267021 Preparation of terpyridines
12/30/2004US20040267020 Process for production cilostazol
12/30/2004US20040267017 3-pyridyl or 4-isoquinolinyl thiazoles as c17, 20 lyase inhibitors
12/30/2004US20040267016 Piperidine derivatives and their use as modulators of chemokine receptor activity (especially ccr5)
12/30/2004US20040267010 For therapy of central nervous system disorders
12/30/2004US20040266855 Effective against Src family; cancer, osteoporosis
12/30/2004US20040266828 Gastrointestinal disorders; facilitating healing and decreasing recurrence of ulcers; low dosage, reduced side effects
12/30/2004US20040266823 Such as N-[1-(3-phenyl-3-benzoylamino]propyl)-4-piperidinyl]-N-ethylmethanesulfonylphenylacetamide; autoimmune and inflammatory diseases; rheumatoid arthritis; synthesis
12/30/2004US20040266821 Obesity, diabetes, sexual dysfunction
12/30/2004US20040266818 Histone deacetylase inhibitors; antiproliferative agents; autoimmune, allergic and inflammatory diseases; central nervous system disorders; potency, bioavailability
12/30/2004US20040266810 Metabolites of tricyclic amides useful for inhibition of G-protein function and methods of treatment of proliferative diseases
12/30/2004US20040266801 Use of tyrosine kinase inhibitors for treating inflammatory bowel diseases (ibd)
12/30/2004US20040266797 Use of potent,selective and non toxic c-kit inhibitors for treating tumor angiogensis
12/30/2004US20040266784 Calcium channel inhibitors comprising benzhydril spaced from piperazine
12/30/2004US20040266782 Cyclic amine derivatives-CCR-3 receptor antagonists
12/30/2004US20040266781 Novel piperazinyl-aryloxy and piperazinyl-heteroaryloxy-n-aryl lactams
12/30/2004US20040266775 for human, veterinary, or phytoprotective use, e.g., inhibiting the cellular sodium-proton antiporter activity, for the treatment of cardiovascular diseases, metabolic diseases, cancerous diseases or fibrotic diseases
12/30/2004US20040266773 Such as 4-(3-methoxyphenyl)-5-methyl-6-(2-fluorobenzyl)-2-(N-(2-pyridyl)ethyl-N -methyl)ethyl-pyridazin-3-one; drugs/prodrugs for treatment of sex-hormone related conditions in men/women
12/30/2004US20040266771 Use of tyrosine kinase inhibitors for treating bone loss
12/30/2004US20040266770 treating diseases that are triggered by persistent angiogenesis; inhibition of the VEGF receptor
12/30/2004US20040266768 Substituted benzoylureidopyridylpiperidine-and-pyrrolidinecarboxylic acid derivatives, processes for preparing them and their use
12/30/2004US20040266764 Hydroxamic acid derivatives
12/30/2004US20040266763 3-(heteroaryl) alanine derivatives-inhibitors of leukocyte adhesion mediated by VLA-4
12/30/2004US20040266762 Indole derivatives having an apoptosis-inducing effect
12/30/2004US20040266760 5-hydroxyindoles with N-oxide groups and the use thereof as therapeutic agents
12/30/2004US20040266759 Possess antithrombotic and anticoagulant properties; example compound: 1-(5-Chlorobenzo[b]furan-2-ylsulphonyl)-4-[4-(4-pyridyl)benzoyl]piperazine
12/30/2004US20040266755 Prodrugs of 1-(1-hydroxy-5-isoquinolinesulfonyl) homopiperazine
12/30/2004US20040266751 Lactam derivatives as inhibitors of matrix metalloproteinases and/or TNF-alpha converting enzyme
12/30/2004US20040266750 Beta-lactamyl vasopressin v1aantagonists
12/29/2004WO2004113331A1 Novel compounds that modulate pparϝ type receptors, and use thereof in cosmetic or pharmaceutical compositions
12/29/2004WO2004113324A1 Chinazoline derivatives as aurora kinase inhibitors
12/29/2004WO2004113323A1 Quinolyl amide derivatives as ccr-5 antagonists
12/29/2004WO2004113322A1 Processes for the preparation of 1-[(benzoimidazole-1yl) quinolin-8-yl] piperidin-4-ylamine derivatives
12/29/2004WO2004113321A1 Method of selectively introducing amino substituent
12/29/2004WO2004113306A1 6-arylamino-5-cyano-4-pyrimidinones as pde9a inhibitors
12/29/2004WO2004113297A2 Aza-ring derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
12/29/2004WO2004113290A1 Substituted alkylamides
12/29/2004WO2004113286A2 Mucin synthesis inhibitors