Patents
Patents for C07D 401 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom (107,979)
11/2004
11/11/2004US20040224925 Method and compositions for treating persistent pulmonary hypertension using aralkyl ester soft drugs
11/11/2004US20040224924 Programming a specific course and rate for a parent drug compound's metabolism that leads to an inactive or weakly active and non-toxic metabolite when the parent drug compound is administered, comprising modifying the parent drug compound by forming one or more of a predetermined chemical arrangement
11/11/2004DE10318611A1 4-, 6- oder 7-Hydroxyindole mit N-Oxidgruppen und deren Verwendung als Therapeutika 4-, 6- or 7-hydroxyindoles with N-oxide groups, and their use as therapeutic agents
11/11/2004DE10318609A1 5-Hydroxyindole mit N-Oxidgruppen und deren Verwendung als Therapeutika 5-Hydroxyindole with a N-oxide groups, and their use as therapeutic agents
11/11/2004CA2536964A1 C-fms kinase inhibitors
11/11/2004CA2523426A1 Aza spiro alkane derivatives as inhibitors of metalloproteases
11/11/2004CA2523336A1 8-(3-biaryl)phenylquinoline phosphodiesterase-4-inhibitors
11/11/2004CA2523102A1 Substituted indoline and indole derivatives
11/11/2004CA2523020A1 Use of derivatives of 2, 4-dihydro-[1,2,4]triazole-3-thione as inhibitors of the enzyme myeloperoxidase (mpo)
11/11/2004CA2522817A1 Imidazolin-2-ylaminophenyl amides as ip antagonists
11/11/2004CA2522431A1 Inhibitors of akt activity
11/11/2004CA2522262A1 Inhibitors of akt activity
11/11/2004CA2521962A1 Anti-diabetic agents
11/11/2004CA2521158A1 Derivatives of 2-acylamino-4-phenylthiazole, preparation method thereof and application of same in therapeutics
11/11/2004CA2520839A1 Quinoxalinone-3- one derivatives as orexin receptor antagonists
11/10/2004EP1475377A1 Derivatives of indole and their use as phosphodiesterase 4 inhibitors
11/10/2004EP1475376A1 Hair composition containing a pyrimidine-n-oxide derivative and its use to stimulate keratinic fiberes growth and/or preventing their loss
11/10/2004EP1475371A1 1-substituted-1-aminomethyl-cycloalkane derivatives (= gabapentin analogues), their preparation and their use in the treatment of neurological disorders
11/10/2004EP1475368A1 N-carbamoyl nitrogen-containing fused ring compounds and drugs containing these compounds as the active ingredient
11/10/2004EP1474420A1 Quinazoline compounds
11/10/2004EP1474416A1 Dihydrobenzodiazepin-2-one-derivatives for the treatment of neurological disorders
11/10/2004EP1474415A1 1-phenyl-2-heteroaryl-substituted benzimidazole derivatives, the use thereof for producing drugs used in the treatment of immunological diseases
11/10/2004EP1474408A1 N-phenyl-2-pyrimidine-amine derivatives
11/10/2004EP1474401A2 Novel aryl- and heteroarylpiperazines
11/10/2004EP1474399A1 Benzenesulfonamide derivatives as antipsychotic agents
11/10/2004EP1474398A1 N-allyloxyethyl-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocines and the use of the same as pharmaceuticals
11/10/2004EP1474396A2 N-substituted3-hydroxy-4-pyridinones and pharmaceuticals containing thereof
11/10/2004EP1474395A1 Nicotinamide derivates useful as p38 inhibitors
11/10/2004EP1474389A2 Delta1-pyrrolines
11/10/2004EP1474148A1 Treatment of neuroblastoma
11/10/2004EP1474147A1 Pyrimidine-based compounds useful as gsk-3 inhibitors
11/10/2004EP1474145A1 Quinoline derivatives as npy antagonists
11/10/2004EP1474139A2 11-beta-hydroxysteroid dehydrogenase 1 inhibitors useful for the treatment of diabetes, obesity and dyslipidemia
11/10/2004EP1474136A1 Use of indole-3-acetic acids in the treatment of asthma, copd and other diseases
11/10/2004EP1474133A2 Crystalline solids of carvedilol and processes for their preparation
11/10/2004EP1473995A1 Derivatives of (1-benzyl-piperidine-4-yl)-diphenyl-methanol and their use as pesticide
11/10/2004EP0929544B1 Tricyclic antitumor compounds being farnesyl protein transferase inhibitors
11/10/2004CN1545520A Ligands and catalyst systems thereof for ethylene oligomerisation to linear alpha olefins
11/10/2004CN1545510A Quinazoline derivatives as alpha-1 adrenergic antagonists
11/10/2004CN1545509A Piperidine derivatives useful as modulators of chemokine receptor activity
11/10/2004CN1544442A 3,6-double(3-methyl pyridine-2yl)-S-tetrazine and transition metal complex, and its preparation and uses
11/10/2004CN1544420A Inhibition of raf kinase using substituted heterocyclic ureas
11/10/2004CN1174978C Heterocyclic compound as inhibitors of rotamase enzymes
11/09/2004US6815547 Quinolylpropylpiperidine derivatives, their preparation, and compositions containing them
11/09/2004US6815460 Process for preparing prodrugs of benzenesulfonamide-containing cox-2 inhibitors
11/09/2004US6815458 Nervous system disorders
11/09/2004US6815456 Antiserotonine agents; central nervous system disorders
11/09/2004US6815455 Benzimidazole compounds and drugs containing the same
11/09/2004US6815451 1,2,3,4-Tetrahydroisoquinolines derivatives as urotensin II receptor antagonists
11/09/2004US6815447 N-type calcium channel antagonists for the treatment of pain
11/09/2004US6815442 Quinoxalinones for enhancing chemotherapy
11/04/2004WO2004094408A1 Substituted pyrimidinones and pyrimidinthiones as crf antagonists
11/04/2004WO2004094407A1 Five-membered heterocyclic derivative
11/04/2004WO2004094406A1 5-hydroxyindoles with n-oxide groups and use thereof as a phosphodiesterase 4 inhibitor
11/04/2004WO2004094405A1 4-, 6- o 7-hydroxyindoles having n-oxide groups and the use thereof as therapeutic agents
11/04/2004WO2004094404A1 4-imidazolin-2-one compounds
11/04/2004WO2004094389A1 Quinoxaline derivatives, and organic semiconductor devices, electroluminescent devices and electronic appliances, made by using the derivatives
11/04/2004WO2004094388A2 Indazole derivatives as jnk inhibitors
11/04/2004WO2004094380A1 (piperidinyloxy)phenyl, (piperidinyloxy)pyridinyl, (piperidinylsulfanyl)phenyl and (piperidinylsulfanyl)pyridinyl compounds as 5-ht1f agonists
11/04/2004WO2004094379A2 3-phenyl-4- (pyrimidin-2-yl) -6- (piperidin-4-yl) derivatives and related compounds as tnf-alpha and il-1 inhibitors for the treatment of inflammations
11/04/2004WO2004093880A1 4-anilino-quinazoline derivatives as antiproliferative agents
11/04/2004WO2004093873A1 2-phenyl-benzimidazol and 2-phenyl-imidazo-`4,5!-pyridine derivatives as checkpoint kinase cds1 (chk2) inhibitors for the treatment of cancer
11/04/2004WO2004093856A2 Combination of a cox-2 inhibitor and an alkylating-type antineoplastic agent for treatment of neoplasia
11/04/2004WO2004093817A2 Chemokine receptor binding heterocyclic compounds with enhanced efficacy
11/04/2004WO2004093798A2 Quinoxalinyl macrocyclic hepatitis c serine protease inhibitors
11/04/2004WO2004093789A2 Use of galr3 receptor antagonists for the treatment of depression and/or anxiety and compounds useful in such methods
11/04/2004WO2004080423A3 7-amino- isoindolyl compounds amd their pharmaceutical uses
11/04/2004WO2004078747A8 Novel cyanopyridine derivatives useful in the treatment of cancer and other disorders
11/04/2004WO2004074812A3 Library of biphenyl derivatives useful for identifying compounds having both beta2 adrenergic receptor agonist and muscarinic receptor antagonist activity
11/04/2004WO2004072062A3 Indolylmaleimide derivatives
11/04/2004WO2004071454A3 Substituted azetidine compounds as inhibitors of dipeptidyl peptidase iv
11/04/2004WO2004069794A3 New arylpiperazinyl compounds
11/04/2004WO2004069792A8 Quinoline-derived amide modulators of vanilloid vr1 receptor
11/04/2004WO2004067703A3 5ht7 antagonists and inverse agonists
11/04/2004WO2004062613A3 Hiv integrase inhibitors
11/04/2004WO2004061084A3 Modulation of protein functionalities
11/04/2004WO2004060865A3 N-(substituted arylmethyl)-4-(disubstituted methyl)piperidines and piperazines
11/04/2004WO2004057960A3 Compounds useful as pesticides
11/04/2004WO2004056774A3 Substituted biphenyl-4-carboxylic acid arylamide analogues as capsaicin receptor modulators
11/04/2004WO2004055001A3 Rabeprazole calcium
11/04/2004WO2004052881A3 Process for preparing (s)-pantoprazole
11/04/2004WO2004050681A3 Kinase modulators
11/04/2004WO2004042351A3 Piperidinyl-alpha-aminoamide modulators of chemokine receptor activity
11/04/2004WO2004037797A3 2 - alkyl - (2 - amino - 3 - aryl - propionyl) - piperazine derivatives and related compounds as melanocortin receptor ligands for the treatment of obesity
11/04/2004WO2004004657A3 Hiv integrase inhibitors
11/04/2004WO2003077847A3 Substituted amides
11/04/2004WO1999029693A8 Imidazonaphthyridines and their use in inducing cytokine biosynthesis
11/04/2004US20040220412 Compositions and kits pertaining to analyte determination
11/04/2004US20040220408 As anti-proliferative agents, therapy
11/04/2004US20040220402 4-(substituted cycloalkylmethyl) imidazole-2-thiones, 4-(substituted cycloalkenylmethyl) imidazole-2-thiones, 4-(substituted cycloalkylmethyl) imidazol-2-ones and 4-(substituted cycloalkenylmethyl) imidazol-2-ones and related compounds
11/04/2004US20040220253 Synthesis of pyrrole amides
11/04/2004US20040220248 Indazole compounds and pharmaceutical compositions for inhibiting protein kinases, and methods for their use
11/04/2004US20040220247 N-[4-(4,5-Dihydro-1H-imidazol-2-yl-amino)-benzyl]-4-methoxy-benzamide and derivatives; prostaglandin inhibitors; urinary tract disease, disease related pain, neuropathic pain, respiratory asthma, allergy
11/04/2004US20040220232 Organometallic reagent reacted with an activated carboxylic acid to produce a ketone which is reacted with carbon disulfide and dihalomethane, further reacting the dithietane product with a secondary amine, and condensing the thioamide with hydrazine; useful as p38 kinase and COX-2 inhibitors
11/04/2004US20040220230 transfroming growth factor antagonist; therapy for urogenital disorders, cardiovascular disorders
11/04/2004US20040220229 insulin resistance; central nervous system disorders; vision defects; anticholesterol agents;antilipemic agents; antiischemic agents
11/04/2004US20040220226 Acid addition salt of optically active piperidine compound and process for preparing the same
11/04/2004US20040220223 Novel human NK3 receptor-selective antagonist compounds, method for obtaining them and pharmaceutical compositions containing them
11/04/2004US20040220222 Malonamide derivatives
11/04/2004US20040220216 controlling signal transduction; angiogenesis inhibitor; anticancer agents; antitumor agents; cardiovascular disorders; vision defects; antiinflammatory agents