Patents
Patents for C07D 217 - Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems (11,865)
01/2014
01/28/2014CA2535265C Compositions and methods for the treatment of disease associated with trp-p8 expression
01/23/2014WO2014014835A2 Crystalline forms of a prolyl hydroxylase inhibitor
01/23/2014WO2014014834A1 Process for making isoquinoline compounds
01/23/2014WO2014014270A1 Isoquinoline-5-carboxamide derivative having inhibitory activity for protein kinase
01/23/2014WO2014012934A1 Novel 5-aminotetrahydroquinoline-2-carboxylic acids and use thereof
01/23/2014US20140024676 Crystalline forms of a prolyl hydroxylase inhibitor
01/23/2014US20140024675 Crystalline forms of a prolyl hydroxylase inhibitor
01/22/2014EP2687507A1 Nitrogen-containing condensed heterocyclic compound
01/22/2014EP2686302A1 Sulfonamide compounds having trpm8 antagonistic activity
01/22/2014CN103524412A Isoquinolone derivative and synthetic method thereof
01/21/2014US8633182 Indanyloxyphenylcyclopropanecarboxylic acids
01/15/2014EP2684468A1 Salty taste enhancer
01/15/2014CN103508940A 6, 6-disubstituted-6-H-benzo[cd]pyrene derivatives and intermediates, and preparation methods and applications of derivatives and intermediates
01/15/2014CN102203067B Hedgehog pathway modulators
01/14/2014CA2623213C Piperazine derivatives as antimalarial agents
01/09/2014WO2014005968A1 Novel adamantyl derivatives as cannabinoid receptor 2 agonists
01/09/2014WO2014005601A1 A process for the preparation of solifenacin or a salt thereof
01/09/2014CA2876443A1 Novel adamantyl derivatives as cannabinoid receptor 2 agonists
01/07/2014US8624032 Compound libraries made through phosphine-catalyzed annulation/Tebbe/Diels-Alder reactions
01/07/2014US8623889 Substituted 6,6-fused nitrogenous heterocyclic compounds and uses thereof
01/07/2014US8623867 Cyclic amine BACE-1 inhibitors having a benzamide substituent
01/03/2014WO2014000694A1 Phendioxin heterocycle derivative
01/03/2014WO2013000651A8 Fluorinated arylalkylaminocarboxamide derivatives
01/02/2014US20140005393 Sulfonamide compounds having trpm8 antagonistic activity
01/02/2014US20140005382 Nitrogen-containing condensed heterocyclic compound
01/01/2014CN103483255A Fluorinated isoquinoline compounds and preparation method thereof
01/01/2014CN103483251A 病毒聚合酶抑制剂 Viral polymerase inhibitor
12/2013
12/31/2013US8618296 Arylethynyl derivatives
12/31/2013US8618295 Preparation of luminescent iridium complexes and precursors thereof
12/31/2013US8618129 Substituted 1-oxo-dihydroisoquinoline-3-carboxamides as KCNQ2/3 modulators
12/31/2013CA2666246C Methods, compounds, compositions and vehicles for delivering 3-amino-1-propanesulfonic acid
12/31/2013CA2643394C Ligands, their preparation and uses thereof in asymmetric reactions
12/31/2013CA2552565C Aryloxyalkylcarbamate-type derivatives, preparation method thereof and use of same in therapeutics
12/31/2013CA2544678C Modulators of cellular adhesion
12/27/2013WO2013189800A1 Cisatracurium and beta-cyclodextrin derivative compositions
12/26/2013US20130345313 Method for the treatment or prevention of lower urinary tract symptoms
12/25/2013EP2675791A1 Substituted 6,7-dialkoxy-3-isoquinolinol derivatives as inhibitors of phosphodiesterase 10 (pde10a)
12/25/2013EP2429295B1 Aryl, heteroaryl, and heterocycle substituted tetrahydroisoquinolines and use thereof
12/25/2013EP2152670B1 Bridged six-membered ring compounds
12/25/2013CN103476757A Substituted 6,7-dialkoxy-3-isoquinolinol derivatives as inhibitors of phosphodiesterase 10 (PDE10A)
12/25/2013CN103476756A 3-ureidoisoquinolin-8-yl derivatives
12/24/2013US8614227 Salt and solvates of a tetrahydroisoquinoline derivative
12/24/2013CA2605510C Inhibitors of microsomal triglyceride transfer protein and apo-b secretion
12/19/2013WO2013185353A1 Compound as wnt signaling inhibitor, composition, and use thereof
12/19/2013US20130338187 Novel 1-(1-OXO-1,2,3,4-TETRAHYDROISOQUINOLIN-7-YL)Urea Derivatives As N-FORMYL Peptide Receptor Like-1 (FPRL-1) Receptor Modulators
12/19/2013CA2875372A1 Compound as wnt signaling inhibitor, composition, and use thereof
12/18/2013EP2673263A1 Novel 1-(1-oxo-1,2,3,4-tetrahydroisoquinolin-7-yl)urea derivatives as n-formyl peptide receptor like-1 (fprl-1) receptor modulators
12/18/2013CN103459369A 胍化合物 Guanidine compound
12/18/2013CN103450079A Tetrahydroisoquinoline hydroxyl derivate, preparation method and medical application thereof
12/18/2013CN103449945A Visible light catalyzed cross-coupling hydrogen desorption method
12/17/2013US8609691 Cyclohexylamin isoquinolone derivatives
12/17/2013CA2749114C Heteroatom-containing cyclic compound
12/17/2013CA2733533C Hedgehog pathway modulators
12/11/2013EP2671869A1 Tetrahydroisoquinoline derivative
12/11/2013EP2670734A1 Novel ether linked compounds and improved treatments for cardiac and cardiovascular disease
12/11/2013CN103443080A Sulfonamide compounds having TRPM8 antagonistic activity
12/11/2013CN103442712A Substituted 3-heteroaroylamino-propionic acid derivatives and their use as pharmaceuticals
12/11/2013CN103435635A Preparation method of magnesium chloride (2,2,6,6-tetramethyl piperidine) lithium salt
12/11/2013CN103435595A Acetylenic heteroaryl compounds
12/11/2013CN103435546A Method for preparing isoquinoline compounds
12/11/2013CN103435545A Tetrahydroisoquinoline quaternary ammonium salt derivatives as well as preparation method and analgesia application thereof
12/11/2013CN102442965B PAR-1 (protease-activated receptor-1) antagonists for treating thrombotic diseases, as well as preparation and application thereof
12/11/2013CN101888999B Pyridylmethyl-sulfonamide compounds
12/10/2013US8604200 Diaza-spiro-{4,4}-nonane derivatives as neurokinin (NK1) antagonists
12/05/2013WO2013178816A1 Heterocycles capable of modulating t-cell responses, and methods of using same
12/05/2013US20130324718 Processes and reagents for making diaryliodonium salts
12/05/2013CA2874938A1 Heterocycles capable of modulating t-cell responses, and methods of using same
12/04/2013EP2667870A1 Substituted 3-heteroaroylamino-propionic acid derivatives and their use as pharmaceuticals
12/04/2013CN203319892U Novel carbon-11 multifunctional automatic synthesis module
12/03/2013US8598364 Oligomer-protease inhibitor conjugates
12/03/2013CA2599411C Enzyme inhibitors
11/2013
11/28/2013WO2013174736A1 N-[3-(2-carboxyethyl)phenyl]piperidin-1-ylacetamide derivatives and use thereof as activators of soluble guanylate cyclase
11/28/2013US20130317010 Tetrahydroisoquinoline derivative
11/28/2013DE102012208530A1 Substituierte Piperidinoacetamide und ihre Verwendung Substituted Piperidinoacetamide and their use
11/27/2013EP2665725A1 Bicyclic inhibitors of alk
11/27/2013CN102757370B Derivatives of p-aminobenzoic acid and applications thereof
11/26/2013US8592608 Triple reuptake inhibitors and methods of their use
11/26/2013US8592451 Reversible nondepolarizing neuromuscular blockade agents and methods for their use
11/26/2013US8592416 Isoquinolin-1 (2H)-one derivatives as PARP-1 inhibitors
11/21/2013US20130310565 Novel nitrogen-containing heteroaryl compounds and methods of use thereof
11/21/2013US20130310559 Isoprenyl compounds and methods thereof
11/21/2013US20130310555 Synthesis of therapeutic and diagnostic drugs centered on regioselective and stereoselective ring opening of aziridinium ions
11/20/2013EP2389226B1 Bridged and fused heterocyclic antidiabetic compounds
11/20/2013CN103402949A A new palladium catalyst, method for its preparation and its use
11/20/2013CN103396361A 3, 4-dihydroisoquinoline antitumor compounds as well as preparation method and application thereof
11/19/2013US8586570 Sox-based kinase sensor
11/14/2013US20130303522 Inhibitor compounds of 11-beta-hydroxysteroid dehydrogenase type 1
11/14/2013US20130303506 Amino-derivatives as novel inhibitors of histone deacetylase
11/12/2013US8580817 1-(1-OXO-1,2,3,4-tetrahydroisoquinolin-7-YL)urea derivatives as N-formyl peptide receptor like-1 (FPRL-1) receptor modulators
11/12/2013CA2621836C Isoquinolines as igf-1r inhibitors
11/12/2013CA2565184C Butanoic acid derivatives, processes for the preparation thereof, pharmaceutical compositions comprising them, and therapeutic applications threreof
11/12/2013CA2537093C Compound capable of binding s1p receptor and pharmaceutical use thereof
11/06/2013CN103384669A Bicyclic inhibitors of ALK
11/05/2013US8575193 N-substituted tetrahydroisoquinoline/isoindoline hydroxamic acid compounds
10/2013
10/31/2013US20130289280 Novel pharmaceutical forms, and methods of making and using the same
10/31/2013US20130289027 Isoquinoline Compounds And Methods For Treating HIV
10/30/2013EP2657227A1 Novel substituted isoquinoline derivative
10/30/2013CN103373971A Urea compounds serving as protein kinase inhibitors
10/30/2013CN103373959A Preparation method of cis-benzyl isoquinoline compound and application thereof
10/30/2013CN101578266B Cycloalkylamine substituted isoquinoline and isoquinolinone derivatives
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