Patents
Patents for C07D 217 - Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems (11,865)
07/2014
07/29/2014US8791263 Cortistatin A analog and use thereof
07/29/2014US8791159 Compound capable of binding S1P receptor and pharmaceutical use thereof
07/24/2014US20140206689 Modulators of atp-binding cassette transporters
07/24/2014US20140206673 Therapeutically active compositions and their methods of use
07/23/2014EP2755954A1 BI-AROMATIC AND TRI-AROMATIC COMPOUNDS AS NADPH OXIDASE 2 (Nox2) INHIBITORS
07/23/2014CN103946214A 作为parp-1抑制剂的3-苯基-异喹啉-1(2h)-酮衍生物 As parp-1 inhibitors of 3-phenyl - isoquinoline -1 (2h) - one derivatives
07/23/2014CN103936538A 一种催化氧化芳硼类化合物制备酚的方法 A catalytic oxidation of an aromatic boron compound of the preparation method of a phenol
07/22/2014US8785643 Substituted bicyclic aromatic compounds as S-nitrosoglutathione reductase inhibitors
07/22/2014US8785642 Process for preparing 6-substituted-1-(2H)-isoquinolinones and intermediate compound
07/22/2014US8785641 Synthesis of tripodal catechol derivatives having an adamantyl basic framework for functionalizing surfaces
07/22/2014US8785473 Plasminogen activator inhibitor-1 inhibitor
07/16/2014CN103930404A 用于抗疟疾治疗方法的取代的2-烷基-1-氧代-n-苯基-3-杂芳基-1,2,3,4-四氢异喹啉-4-酰胺 2-alkyl substituted-1-oxo antimalarial treatment method for -n- phenyl-3-heteroaryl-1,2,3,4-tetrahydro-isoquinoline-4-carboxamide
07/16/2014CN103929961A 化合物及其治疗应用 Compounds and their therapeutic applications
07/16/2014CN103923006A 构建异喹啉酮骨架的方法及生物碱8-oxypseudopalmatine的合成 Synthesis method for constructing isoquinolone skeleton and alkaloid 8-oxypseudopalmatine of
07/16/2014CN103923005A 手性胺类化合物的制备方法及其应用 Preparation of chiral amines and its application
07/15/2014US8779171 Hydroxamates as therapeutic agents
07/15/2014US8779144 Bicycloheteroaryl compounds as P2X7 modulators and uses thereof
07/15/2014US8778925 Pyridine and pyrimidine based compounds as Wnt signaling pathway inhibitors for the treatment of cancer
07/10/2014US20140193518 Kinase inhibitor compounds
07/09/2014CN103910725A 一类吡喹酮类似物、其制备方法和用途 A class of praziquantel analogs, their preparation and use
07/09/2014CN103910676A 一种多取代四氢异喹啉衍生物的合成方法 A multi-synthesis method to replace tetrahydroisoquinoline derivatives
07/08/2014US8772492 Substituted isoquinoline and isoquinolinone derivatives
07/08/2014CA2512582C Antibacterial agents
07/03/2014WO2014104235A1 1,2,4-tris-substituted benzene compound and method for producing same, and organic electroluminescent element
07/03/2014WO2014103644A1 Actinic-ray-sensitive or radiation-sensitive resin composition, resist film formed using said composition, method for forming pattern using said composition, process for producing electronic device, and electronic device
07/03/2014WO2013189800A9 Cisatracurium and beta-cyclodextrin derivative compositions
07/03/2014US20140187786 1,3,4-trisubstituted benzenes
07/02/2014EP2748147A1 Substituted 2-alkyl-1-oxo-n-phenyl-3-heteroaryl-1,2,3,4-tetrahydroisoquinoline-4-carboxamides for antimalarial therapies
07/02/2014CN102844305B 抗菌异喹啉-3-基脲衍生物 Antibacterial isoquinoline-3-yl urea derivatives
07/01/2014US8765956 Nitrogen-containing heteroaryl compounds and methods of use thereof
06/2014
06/26/2014WO2014100730A1 Prmt5 inhibitors containing a dihydro- or tetrahydroisoquinoline and uses thereof
06/26/2014WO2014100719A2 Prmt5 inhibitors and uses thereof
06/26/2014WO2014100695A1 Prmt5 inhibitors and uses thereof
06/25/2014EP2746254A2 Oxadiazole derivative active on sphingosine-1-phosphate (s1p)
06/25/2014CN103889969A 新方法 New Method
06/25/2014CN103880827A 芳基和杂芳基取代的四氢异喹啉及其阻断去甲肾上腺素、多巴胺和血清素的重摄取的应用 Aryl and heteroaryl substituted tetrahydroisoquinoline and its application to block reuptake of norepinephrine, dopamine and serotonin
06/25/2014CN103880745A 一种6-溴-1,2,3,4-四氢异喹啉-1-甲酸的化学合成方法 One kind of chemical synthesis of 6-bromo-1,2,3,4-tetrahydro-isoquinoline-1-carboxylic acid
06/25/2014CN103880744A 一种5'-甲氧基劳丹素的制备方法 Method for preparing 5'-methoxy 基劳丹 Pigment
06/25/2014CN101522614B 作为阿片样物质受体的拮抗剂或反向激动剂的化合物 Compounds as opioid receptor antagonists or inverse agonists of substance
06/24/2014US8759374 Certain chemical entities, compositions, and methods
06/19/2014WO2014091167A2 Cyclopropylboronic compounds, method for preparing same and use thereof
06/19/2014US20140171439 Inhibitors Of Histone Deacetylase
06/18/2014CN103864684A Synthesis of novel 3,4-dihydro-1(2H)isoquinoline derivatives and application in antitumor drugs
06/12/2014WO2014087298A1 Novel selective androgen receptor modulators
06/12/2014WO2014087165A1 Tankyrase inhibitors
06/12/2014US20140163061 Methods For Reducing Blood Pressure
06/12/2014US20140163042 Enzyme inhibitors
06/11/2014EP2739609A1 Novel estrogen receptor ligands
06/11/2014EP2739144A1 Compounds and therapeutic uses thereof
06/11/2014CN102863380B Preparation method of 1-alkynyl-2-aryl-1,2,3,4-tetrahydroisoquinoline compound
06/10/2014US8748614 Substituted isoquinoline and isoquinolinone derivatives
06/10/2014US8748582 Affinity ligands and methods for protein purification
06/04/2014CN103842341A Novel estrogen receptor ligands
06/04/2014CN103833729A Method using visible light catalyzed cross-coupling reaction to prepare coupling product and release hydrogen
06/04/2014CN103833631A Application of tetrahydroisoquinoline compound for preparing drug killing animal mites
06/04/2014CN103833544A 11-beta-hydroxysteroid dehydrogenase type i inhibitors
06/04/2014CN102264704B Isoquinoline derivative
06/04/2014CN102083797B Tetrahydroisoquinolines, pharmaceutical compositions containing them, and their use in therapy
06/03/2014US8741901 Aryl- and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
06/03/2014US8741259 Low molecular weight thyroid stimulating hormone receptor (TSHR) agonists
05/2014
05/30/2014WO2014081697A2 Anthelmintic compounds and compositions and method of using thereof
05/30/2014WO2014079504A1 Polycyclic ligands of 5-ht7 receptor and use thereof
05/28/2014EP2734504A1 Polymorphic forms of compounds as prolyl hydroxylase inhibitor, and uses thereof
05/28/2014CN103819403A 用于治疗与体液潴留或盐超负荷有关的病症和胃肠道病症的化合物和方法 Compounds and methods for the treatment of fluid overload or salt retention and gastrointestinal disorders associated disorders
05/28/2014CN102516169B 制备多取代异喹啉及杂环并吡啶衍生物的方法 Preparation of poly-substituted heterocyclic isoquinoline and pyridine derivatives and methods
05/28/2014CN102471275B Smac模拟物 Smac mimetics
05/27/2014US8735425 Tetrahydroisoquinoline derivative
05/22/2014US20140142136 Enhanced Erythropoiesis and Iron Metabolism
05/22/2014US20140142116 Method of Treatment or Prophylaxis of Inflammatory Pain
05/22/2014US20140141062 Compositions and methods for treatment
05/21/2014CN103814022A 3,4-二氢异喹啉衍生物的制造方法及它们的制造中间体 The method of producing 3,4-dihydro-isoquinoline derivatives and their production intermediates
05/21/2014CN103814014A 3,4-二氢异喹啉衍生物的制造方法 The method of producing 3,4-dihydro-isoquinoline derivatives
05/20/2014CA2518513C N-alkyl-hydroxamic acid-isoindolyl compounds and their pharmaceutical uses
05/15/2014WO2014074775A1 Heteroaryl derivatives and uses thereof
05/15/2014WO2014074365A1 Novel benzyl sulfonamide compounds useful as mogat-2 inhibitors
05/15/2014US20140135338 Quinolinyl glucagon receptor modulators
05/15/2014US20140135327 N- (2 -aminophenyl) benzamide derivatives as histone deacetylase inhibitors
05/15/2014US20140135325 Novel ezrin inhibitors and methods of making and using
05/15/2014US20140135306 Hdyroxy substituted isoquinolinone derivatives
05/14/2014EP2729450A1 N- (2 -aminophenyl) benzamide derivatives as histone deacetylase inhibitors
05/14/2014CN103787969A 一种(1s)-1-苯基-3,4-二氢-2(1h)-异喹啉甲酸酯的制备方法 One kind of (1s) -1- phenyl-3,4-dihydro -2 (1h) - isoquinoline carboxylate of Preparation
05/14/2014CN103787927A 递送3-氨基-1-丙磺酸的方法、化合物、组合物和载体 3-amino-1-propanesulfonic acid delivery methods, compounds, compositions, and vectors
05/14/2014CN102603552B 一种α-酮酰胺的制备方法 Method for preparing α- keto amide
05/13/2014US8722671 Isoquinoline derivatives
05/13/2014CA2758144C Cyclic compound having substituted phenyl group
05/08/2014WO2014069510A1 Novel amine derivative or salt thereof
05/08/2014WO2014067219A1 Preparation method of (1s)-1-phenyl-3,4-dihydro-2(1h)-isoquinoline carboxylate
05/08/2014US20140128428 Cold menthol receptor antagonists
05/08/2014US20140128365 Pyridone/hydroxypyridine 11-beta hydroxysteroid dehydrogenase type i inhibitors
05/08/2014US20140128361 Cyclic amide bace-1 inhibitors having a benzamide substituent
05/07/2014EP2727911A1 Novel means and methods for treating malaria and other parasitic disorders
05/07/2014CN103781759A 氟化的芳基烷基氨基甲酰胺衍生物 Fluorinated aryl alkyl amino carboxamide derivatives
05/07/2014CN103776932A 一种hplc法分析分离丁苯那嗪及其中间体的方法 One kind hplc analysis method for separating its intermediate tetrabenazine
05/07/2014CN103772279A 4-溴代异喹啉酮及其衍生物的制备方法 Preparation of 4-bromo-isoquinolone its derivatives
05/07/2014CN103772278A 一种重要四氢异喹啉衍生物中间体及其合成方法 An important intermediate tetrahydroisoquinoline derivatives and synthetic method
05/07/2014CN103772120A 新颖的有机电致发光化合物和使用该化合物的有机电致发光设备 Novel organic electroluminescent compounds and the use of the compound organic electroluminescent devices
05/06/2014US8716481 Process for the preparation of 6-substituted-1-(2H)-isoquinolinones
05/06/2014US8716302 Compounds for inducing cellular apoptosis
05/01/2014WO2014066613A2 Sphingolipid metabolite mimetics
05/01/2014WO2014064476A1 The synthesis of tetrahydroisoquinolines from 2-methyl-1-phenyl substituted indenes
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