Patents
Patents for C07D 217 - Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems (11,865)
11/2014
11/06/2014US20140329794 Prmt5 inhibitors and uses thereof
11/04/2014US8877929 Process for synthesizing substituted isoquinolines
11/04/2014US8877784 TRPA1 antagonists
10/2014
10/30/2014US20140323519 Heterocyclic compounds as b-raf inhibitors for treatment of cancer
10/30/2014US20140323518 Novel estrogen receptor ligands
10/30/2014US20140323487 Novel Compounds As Antagonists Or Inverse Agonists At Opioid Receptors
10/28/2014US8871935 Crystalline pharmaceutical and methods of preparation and use thereof
10/28/2014US8871757 6-and 7-amino isoquinoline compounds and methods for making and using the same
10/23/2014US20140315946 Nonpeptide hiv-1 protease inhibitors
10/23/2014US20140315939 Antimicrobial agents
10/21/2014US8865901 Gain-of-function Bcl-2 inhibitors
10/21/2014US8865898 Nucleoside analog or salt thereof, oligonucleotide analog, gene expression inhibitor, and nucleic-acid probe for detecting gene
10/21/2014US8865709 Aminooxazole inhibitors of cyclin dependent kinases
10/21/2014US8865704 Wnt pathway antagonists
10/21/2014US8865702 B1-antagonists
10/16/2014US20140309253 Substituted 6,7-dialkoxy-3-isoquinolinol derivatives as inhibitors of phosphodiesterase 10 (pde 10a)
10/16/2014US20140309190 Bicyclic aryl sphingosine 1-phosphate analogs
10/14/2014US8859814 Alpha-substituted N-sulfonyl gylcine amides antagonists of CCR10, compositions containing the same and methods for using them
10/14/2014US8859599 Androgen receptor modulating compounds, preparation and uses thereof
10/14/2014US8859586 Cyclohexyl isoquinolinone compounds
10/14/2014US8859541 6-alkynylpyridines
10/14/2014US8859535 Hydroxy substituted isoquinolinone derivatives
10/09/2014US20140303202 Crystalline forms of a prolyl hydroxylase inhibitor
10/09/2014US20140303170 Compounds for treating disease, for administering, and for pharmaceutical compositions
10/09/2014US20140301976 Novel hydroxamates as therapeutic agents
10/08/2014EP2785695A1 New bicyclic dihydroisoquinoline-1-one derivatives
10/07/2014US8853392 Benzamide mGluR5 positive allosteric modulators and methods of making and using same
10/07/2014US8853242 Nitrogenous-ring acylguanidine derivative
10/02/2014WO2014160723A1 Compounds for the treatment of glioma
10/02/2014WO2014159501A2 Processes for preparing tetrahydroisoquinolines
10/02/2014US20140296256 Plasminogen activator inhibitor-1 inhibitor
10/02/2014US20140296212 Substituted phenoxypropylcycloamine derivatives as histamine-3 (h3) receptor ligands
09/2014
09/30/2014US8846937 Mono quaternary ammonium salts and methods for modulating neuronal nicotinic acetylcholine receptors
09/25/2014WO2014146747A1 Piperazine derivatives as fasn inhibitors
09/25/2014US20140288309 Process of producing bleach boosters
09/25/2014US20140288059 Therapeutic compositions and methods
09/25/2014US20140288034 Compound capable of binding s1p receptor and pharmaceutical use thereof
09/24/2014EP2780324A1 Heterocyclic carboxamides useful as inhibitors of phosphodiesterase type 10a
09/18/2014WO2014142219A1 Guanidinobenzoic acid ester compound
09/18/2014WO2014139963A1 Cosmetic compositions with tricyclodecane amides
09/18/2014US20140275529 Subunit selective nmda receptor potentiators for the treatment of neurological conditions
09/18/2014US20140275160 Combination therapy
09/18/2014US20140275158 Cyclohexyl isoquinolinone compounds
09/18/2014US20140275061 Substituted tetrahydroisoquinoline compounds as factor xia inhibitors
09/17/2014EP2776396A2 Heteroaryl hydroxamic acid derivatives and their use in the treatment, amelioration or prevention of a viral disease
09/16/2014US8835472 Compounds, pharmaceutical compositions and uses thereof
09/11/2014US20140256767 Direct inhibitors of keap1-nrf2 interaction as antioxidant inflammation modulators
09/11/2014US20140256685 Use of agonists of formyl peptide receptor 2 for treating dermatological diseases
09/11/2014US20140256684 Use of agonists of formyl peptide receptor 2 for treating ocular inflammatory diseases
09/09/2014US8829204 Modulators of ATP-binding cassette transporters
09/09/2014US8829034 Compounds which modulate the CB2 receptor
09/09/2014US8829025 Anti-cancer compounds
09/04/2014WO2014134388A1 Phenylpyrazole derivatives as potent rock1 and rock2 inhibitors
09/03/2014EP2771331A1 Novel process
09/02/2014US8822467 Biaryl oxyacetic acid compounds
08/2014
08/28/2014WO2014066613A3 Sphingolipid metabolite mimetics
08/28/2014US20140243524 Aryl- and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
08/28/2014US20140243345 Selective hdac3 inhibitors
08/28/2014US20140243333 Synthesis of functionalized octahydro-isoquinolin-1-one-8-carboxylic esters and analogs, and therapeutic methods
08/26/2014US8816087 Hydroxybenzamide derivatives and their use as inhibitors of Hsp90
08/26/2014US8815898 6,7-disubstituted-sioquinoline derivatives and their use
08/26/2014US8815849 Hetero-bicyclic derivatives as HCV inhibitors
08/21/2014WO2014087298A4 Novel selective androgen receptor modulators
08/21/2014WO2014014835A3 Criystalline forms of the prolyl hydroxylase inhibitor [(4-hydroxy-1-methyl-7-phenoxy-isoquinoline-3-carbonyl)-amino]-acetic acid
08/20/2014EP2766347A1 Substituted tetrahydroisoquinoline compounds as factor xia inhibitors
08/20/2014EP2766346A1 Substituted tetrahydroisoquinoline compounds as factor xia inhibitors
08/20/2014EP2766345A1 Substituted tetrahydroisoquinoline compounds as factor xia inhibitors
08/19/2014US8809381 Highly selective sigma receptor ligands
08/19/2014US8809367 1-1-Oxo-1,2,3,4-tetrahydroisoquinolin-7-yl)urea derivatives as N-formyl peptide receptor like-1 (FPRL-1) receptor modulators
08/19/2014US8809326 Isoquinolinone Rho kinase inhibitors
08/19/2014CA2623462C Substituted 4-phenyltetrahydroisoquinolines, method of producing them, their use as medicament, and also medicament containing them
08/14/2014WO2014100719A3 Teatrahydro- and dihydro-isoquinoline prmt5 inhibitors and uses thereof
08/14/2014US20140228576 Method for producing 3,4-dihydroisoquinoline derivatives and production intermediates of same
08/14/2014US20140228343 Prmt5 inhibitors and uses thereof
08/13/2014CN103987697A 作为因子xia抑制剂的取代的四氢异喹啉化合物 As the substituted tetrahydroisoquinoline compounds factor inhibitors xia
08/13/2014CN103987696A 作为因子xia抑制剂的取代的四氢异喹啉化合物 As the substituted tetrahydroisoquinoline compounds factor inhibitors xia
08/13/2014CN103980195A 酰胺类苯基哌嗪衍生物及其盐与在制备治疗良性前列腺增生症药物中的应用 Amides phenyl piperazine derivatives and salts in the preparation and application of the treatment of benign prostatic hyperplasia medicine
08/13/2014CN103980151A 作为阿片样物质受体的拮抗剂或反向激动剂的新型化合物 Novel compounds as opioid receptor antagonists or inverse agonists of substance
08/12/2014US8802711 TRPV1 antagonists
08/12/2014US8802688 Substituted acetyl-coa carboxylase inhibitors
08/07/2014WO2014117919A1 Positive allosteric modulators of mglur3
08/07/2014WO2014091167A3 Cyclopropylboronic compounds, method for preparing same and use thereof
08/07/2014US20140221345 Prmt5 inhibitors and uses thereof
08/07/2014US20140220122 Methods, compounds, compositions and vehicles for delivering 3-amino-1-propanesulfonic acid
08/07/2014US20140219995 Inhibitors of bacterial type iii secretion system
08/07/2014US20140219989 Factor ixa inhibitors
08/06/2014EP2762474A1 Production methods for 3,4-dihydroisoquinoline derivatives, and production intermediates for same
08/06/2014CN103974938A 作为因子xia抑制剂的经取代的四氢异喹啉化合物 As inhibitors of factor xia substituted tetrahydroisoquinoline compound
08/06/2014CN103965109A 一种合成可旦民碱的方法 Once people can base a method for the synthesis of
08/06/2014CN103965108A 一种合成劳丹宁的方法 A synthetic method for Lao Danning
08/05/2014US8796458 Cyclohexylamine isoquinolone derivatives
08/05/2014CA2565238C Amido compounds and their use as pharmaceuticals
07/2014
07/31/2014WO2014116849A1 Crystalline forms of {[1-cyano-5-(4-chlorophenoxy)-4-hydroxy-isoquinoline-3-carbonyl]-amino}-acetic acid
07/31/2014US20140213785 Process for preparing aromatic and heteroaromatic amines
07/31/2014US20140212359 Photostable aie luminogens for specific mitochondrial imaging and its method of manufacturing thereof
07/30/2014CN103958478A 新双环二氢异喹啉-1-酮衍生物 New bicyclic dihydro-isoquinolin-1-one derivative
07/30/2014CN103958475A 杂芳基异羟肟酸衍生物及其在治疗、减轻或预防病毒疾病中的用途 Heteroaryl hydroxamic acid derivatives and their use in the treatment, alleviation or prevention of viral diseases in
07/30/2014CN103951671A 四氢异喹啉类化合物、制备方法及抗肿瘤用途 Tetrahydroisoquinoline compounds, preparation and use of anti-tumor
07/30/2014CN102348682B 1,1,1-三氟-2-羟基丙基化合物 1,1,1-trifluoro-2-hydroxy-propyl compound
07/30/2014CN101641013B 核受体结合剂 Nuclear receptor binding agent
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